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Mini Episode: Bridging the Gap- Bupropion's not your average wide QRS with Dr. Travis Olives
Manage episode 355440525 series 3382933
Content provided by Ryan Feldman and Ryan Feldman PharmD DABAT. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Ryan Feldman and Ryan Feldman PharmD DABAT or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
- Rohr 2004- Gap junction blockade can cause a wide QRS
- Vink 2004 Connexin 43 is the most important protein for connexon formation and cardiac signal transmission
- Callier 2012- Bupropion does not block sodium channels, and does exhibit similar effects on the cardiac action potential as known gap junction
- Burnham 2014 Bupropion has an IC50 for connexin 43 >50 uMol, larger than other drugs such as fluoextine and lamotrigine
- Shaikh Quereshi 2014 Bupropion interferes with connexin43 production and localization in chicken cardiac myoctes at concentration >50 uMol
56 episodes
Share
Manage episode 355440525 series 3382933
Content provided by Ryan Feldman and Ryan Feldman PharmD DABAT. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Ryan Feldman and Ryan Feldman PharmD DABAT or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
- Rohr 2004- Gap junction blockade can cause a wide QRS
- Vink 2004 Connexin 43 is the most important protein for connexon formation and cardiac signal transmission
- Callier 2012- Bupropion does not block sodium channels, and does exhibit similar effects on the cardiac action potential as known gap junction
- Burnham 2014 Bupropion has an IC50 for connexin 43 >50 uMol, larger than other drugs such as fluoextine and lamotrigine
- Shaikh Quereshi 2014 Bupropion interferes with connexin43 production and localization in chicken cardiac myoctes at concentration >50 uMol
56 episodes
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Similar to The Poison Lab
How can we, humans, look at our relationship to nature differently? In season three of Going Wild, on top of stories about animals, we invite you to journey through the entire ecological web — from the tiniest of life forms to apex predators — alongside the scientists, activists and adventurers who study it. Wildlife biologist and host Dr. Rae Wynn-Grant has been studying wild animals in their natural habitats all over the world for years. Our award-winning podcast takes you inside the hidde ...
…
continue reading
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…
continue reading
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…
continue reading
Deep in the back of your mind, you’ve always had the feeling that there’s something strange about reality. There is. Join Robert Lamb and Joe McCormick as they examine neurological quandaries, cosmic mysteries, evolutionary marvels and our transhuman future.
…
continue reading
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…
continue reading
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