Bitcoin pioneer Charlie Shrem peels back the layers on the lives and backgrounds of the world's most impactful innovators. Centering around intimate narratives, Shrem uncovers a detailed, previously unspoken story of the genesis and evolution of bitcoin, cryptocurrency, artificial intelligence, and the web3 movements. Join Shrem as he journeys through the uncharted territories of tech revolutions, revealing the human side of the stories that shaped the digital world we live in today.
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Recce Starts Phase 2 R327 Gel trial for bacterial skin infections
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Manage episode 425459990 series 2891889
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Recce Pharmaceuticals Ltd (ASX:RCE, OTC:RECEF) CEO James Graham joins Jonathan Jackson in the Proactive studio after the company obtained Human Research Ethics Committee (HREC) approval to initiate a Phase 2 clinical trial of RECCE® 327 (R327) Gel for acute bacterial skin and skin structure infections (ABSSSI). This trial aims to position R327 Gel as a broad-spectrum treatment for various bacterial skin infections, including complicated skin and soft tissue infections. The trial is an open-label efficacy study and exploratory evaluation designed to assess the systemic bioavailability of single and/or multiple doses of the R327 topical gel applied to ABSSSI, including diabetic foot infections, necrotising fasciitis, and post-operative wound infections. The study seeks to gather critical data on the gel's effectiveness in treating a wide range of ABSSSI conditions. Graham stated that obtaining HREC approval is a significant milestone for the company, highlighting their history of successful approvals and the dedication of their clinical and research teams. The company collaborates with Barwon Health to conduct the trial, enabling access to a diverse patient population and providing valuable insights into the gel's performance across various ABSSSI conditions. Site initiation has begun, with the first patients expected to be dosed in the third quarter of the year. This study builds on previous clinical results from testing R327 on infected burn wounds and diabetic foot infections, under the TGA Special Access Scheme Category A initiative. The centralised study approach aims to address a broad range of unmet medical needs in the topical bacterial infection landscape. ABSSSIs pose a significant challenge to the healthcare system, exacerbated by the rise of antimicrobial resistance, particularly methicillin-resistant Staphylococcus aureus (MRSA). Diabetic patients are at high risk of skin infections and poor outcomes from ABSSSI. The global ABSSSI treatment market was valued at US$7.3 billion in 2018 and is projected to reach US$26 billion by 2032, with a compound annual growth rate of 9.5% from 2019 to 2032. #ProactiveInvestors #ASX #ReccePharmaceuticals, #R327Gel, #ABSSSI, #ClinicalTrial, #Phase2, #HRECApproval, #BacterialInfections, #SkinInfections, #DiabeticFootInfections, #NecrotisingFasciitis, #WoundInfections, #BarwonHealth, #AntimicrobialResistance, #MRSA, #TopicalTreatment, #Healthcare, #PharmaceuticalResearch, #TGA, #InfectionTreatment, #MedicalResearch #invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews
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605 episodes
MP3•Episode home
Manage episode 425459990 series 2891889
Content provided by Proactive Investors. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Proactive Investors or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
Recce Pharmaceuticals Ltd (ASX:RCE, OTC:RECEF) CEO James Graham joins Jonathan Jackson in the Proactive studio after the company obtained Human Research Ethics Committee (HREC) approval to initiate a Phase 2 clinical trial of RECCE® 327 (R327) Gel for acute bacterial skin and skin structure infections (ABSSSI). This trial aims to position R327 Gel as a broad-spectrum treatment for various bacterial skin infections, including complicated skin and soft tissue infections. The trial is an open-label efficacy study and exploratory evaluation designed to assess the systemic bioavailability of single and/or multiple doses of the R327 topical gel applied to ABSSSI, including diabetic foot infections, necrotising fasciitis, and post-operative wound infections. The study seeks to gather critical data on the gel's effectiveness in treating a wide range of ABSSSI conditions. Graham stated that obtaining HREC approval is a significant milestone for the company, highlighting their history of successful approvals and the dedication of their clinical and research teams. The company collaborates with Barwon Health to conduct the trial, enabling access to a diverse patient population and providing valuable insights into the gel's performance across various ABSSSI conditions. Site initiation has begun, with the first patients expected to be dosed in the third quarter of the year. This study builds on previous clinical results from testing R327 on infected burn wounds and diabetic foot infections, under the TGA Special Access Scheme Category A initiative. The centralised study approach aims to address a broad range of unmet medical needs in the topical bacterial infection landscape. ABSSSIs pose a significant challenge to the healthcare system, exacerbated by the rise of antimicrobial resistance, particularly methicillin-resistant Staphylococcus aureus (MRSA). Diabetic patients are at high risk of skin infections and poor outcomes from ABSSSI. The global ABSSSI treatment market was valued at US$7.3 billion in 2018 and is projected to reach US$26 billion by 2032, with a compound annual growth rate of 9.5% from 2019 to 2032. #ProactiveInvestors #ASX #ReccePharmaceuticals, #R327Gel, #ABSSSI, #ClinicalTrial, #Phase2, #HRECApproval, #BacterialInfections, #SkinInfections, #DiabeticFootInfections, #NecrotisingFasciitis, #WoundInfections, #BarwonHealth, #AntimicrobialResistance, #MRSA, #TopicalTreatment, #Healthcare, #PharmaceuticalResearch, #TGA, #InfectionTreatment, #MedicalResearch #invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews
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