Best Actnet Podcasts (2024)

1
Frontiers in Clinical Tuberculosis Microbiology - New TBI Diagnostics with Prof Martineau 30:08

9h ago30:08

30:08

Professor Adrian Martineau from the Queen Mary University London talks to us about the limitations of current latent TB infection diagnosis and how we can do better. his research into whether we can use fragments of TB DNA found in bone marrow cells to better predict who should be treated with Tuberculosis Preventative Treatment. REFERENCES Martine…

1
MTBVAC - one of the most promising new TB Vaccines with Dr Carlos Martín Montañés 42:58

29d ago42:58

42:58

Today we discuss the MTBVAC with Dr Montañés. MTBVAC is an attenuated vaccine from a human mycobacterial isolate which has just progressed to a phase 3 trial and shown very promising results in the phase 2 study. Dr Montañés has been involved in this project for over a decade and has an incredible insight into the development and promise of this va…

1
TB Contact Tracing and Building Research in TB with Prof Philip Hill 30:13

2M ago30:13

30:13

Prof Greg Fox speaks with Prof Philip Hill about TB household contact tracing and building research capacity in TB. Prof Hill is an ID specialist and public health physician who did his PhD in TB Epidemiology. He is the current McAuley Chair in International Health as well as being Founding Direction & Co-Director of the Centre for International He…

1
END-TB Trial with Dr Guglielmetti 46:27

3M ago46:27

46:27

Today we speak with Dr Guglielmetti about the END-TB trial which looks at new all oral regimens for MDR-TB. REFERENCES 1) https://endtb.org/ 2) Nyang’wa, Bern-Thomas, et al. "A 24-week, all-oral regimen for rifampin-resistant tuberculosis." New England Journal of Medicine 387.25 (2022): 2331-2343. 3) Conradie, Francesca, et al. "Treatment of highly…

1
Tuberculosis Diagnostics & Emerging Technologies with Dr Morten Ruhwald 24:14

4M ago24:14

24:14

Today we delve into the world of TB diagnostics and the future of leveraged TB technologies with Dr Morten Ruhwald. Dr Ruhwald is a the head of the TB programme over at FIND, an institution dedicated to accelerating equitable access to reliable diagnosis around the world. Dr Ruhwald elaborates on the current state of TB diagnostics, new clinical st…

1
Tuberculosis Nursing Challenges in Australia's Northern Territory with Dr Chris Lowbridge 36:21

5M ago36:21

36:21

Today we speak with Dr Chris Lowbridge about the amazing work of the TB teams in the Northern Territory. Chris talks about the challenges of controlling tuberculosis across 1.42 million square kilometres, more than 100 local languages, and some very isolated communities. References Meumann, Ella M., et al. "Tuberculosis in Australia's tropical nort…

1
Drug Development with Dr Clifton Barry 42:02

6M ago42:02

42:02

Today we speak with Dr Clifton Barry from NIH in Bethesda, Maryland who is head of the most highly cited research group in the field of TB over the past year and has made extraordinary contributions to TB drug development. Dr Barry speaks about his involvement in the PREDICT TB study, the TB Drug Accelerator and some of the most exciting drug devel…

1
Where are we with TB Vaccines - with Prof Triccas 40:33

7M ago40:33

40:33

Today we get an update on where the TB Vaccine pipeline is up to, how TB vaccines work and what exciting candidates might be on the horizon. We speak with Professor Jamie Triccas from the University of Sydney about his work as the principal investigator on the Advancing Vaccine Adjuvant Research for Tuberculosis (AVAR-T) which is an NIH funded proj…

1
What does TB Elimination mean? 40:43

8M ago40:43

40:43

Today we have the pleasure of speaking with Professor Giovanni Migliori about TB Elimination. Professor Migliori is the director of the WHO collaborating centre for TB and lung disease and is the current chief editor for the international journal of TB and lung disease. He was formerly the secretary general of the ERS and president of the Union's E…

1
Papua New Guinean Challenges of TB in Pregnancy 34:15

9M ago34:15

34:15

Today we speak with Prof Mola, Dr Welch and Dr Visiliu about their amazing work tackling TB in pregnancy in Papua New Guinea. They talk about the epidemiological, geographical and social challenges of providing maternal TB care in PNG along with some insights into treatment and control. REFERENCES: Hamada, Yohhei, et al. "The safety of isoniazid tu…

1
How WGS is shaping the public health in Australia 40:32

10M ago40:32

40:32

Today we speak with Professor Justin Denholm about his work with the National TB Advisory Committee in Australia and the role whole genome sequencing (WGS) has in public health. Professor Denholm talks about how WGS is expanding the way we think about tuberculosis and how this WGS can bring us into a new age of TB elimination strategy. REFERENCES 1…

1
Discovery of tuberculosis - the life of Robert Koch 48:22

11M ago48:22

48:22

In this extraordinary episode we speak with renowned historian Professor Christoph Gradmann about the life and work of German physician Robert Koch. In this episode we look at how Koch came to discover tuberculosis and what it meant for the field of medicine in the late 19th century. REFERENCES: Gradmann, Christoph. "Robert Koch and the pressures o…

1
Differentiating TB from Sarcoid 32:03

1y ago32:03

32:03

Today we have the pleasure of speaking to both Professor Leonard (Respiratory physician and director of the sarcoidosis service for Manchester Foundation Trust) and Dr Montero (director of cellular pathology for Wythenshawe Hospital) about the complex interplay between these two illnesses and how best to approach complex patients with uncertain dia…

1
Mind the Gap - Update on Global TB Goals 45:13

1y ago45:13

45:13

Today I had the privilege of speak with Professor Christoph Lange, Secretary General of the Union, founding chairman of TBNet and is the clinical lead for the Unite4TB Consortium. Professor Lange spoke to us about where we're up to with our EndTB Goals. Professor Lange spoke about the significant barriers that remain, where our shortfalls have come…

1
Understanding TB Diagnostic Tests 40:07

1y ago40:07

40:07

Today I had the pleasure of speaking with Dr Emily MacLean about the exciting modern tests both commercially available and in research development for diagnosing tuberculosis. Emily talked to us about how GeneXpert has evolved and how we can get the most out of this amazing test but also about the extraordinary diagnostic tests being investigated a…

1
Understanding TB Screening Tests 32:50

1+ y ago32:50

32:50

Today I had the pleasure of speaking with Dr Geoff Eather from the Princess Alexandra Hospital in Brisbane about his work and research on TST and IGRA screening for tuberculosis. This was a fantastic experience to learn more about these incredibly common tests from an expert in this field of research. REFERENCES: Auguste, Peter, et al. "Comparing i…

1
Tuberculosis Modelling 30:39

1+ y ago30:39

30:39

Today I had the pleasure of speaking to Hojoon Sohn, an associate professor in infectious disease epidemiologist at the Seoul National University College of Medicine. Hojoon is an expert in TB modelling and speaks to us about his research in decentralised models of testing. This was a fascinating podcast about an area of Tuberculosis not often enco…

1
Therapeutic Drug Monitoring in TB 33:48

1+ y ago33:48

33:48

Today we speak to Professor Jan-Willem Alffenaar from Westmead Hospital and the University of Sydney about Therapeutic Drug Monitoring in Tuberculosis. Professor Alffenaar reviews the PK/PD issues with common TB medications, the strengths and weaknesses of TDM and how best to utilise TDM in the treatment of TB patients. REFERENCES 1) personalised d…

1
Predicting Side Effects in 3HP 18:09

1+ y ago18:09

18:09

Today we speak with Professor Jann-Yuan Wang, a clinician and researcher in Taiwan, about his work in latent tuberculosis. Professor Wang speaks about his experience using 3HP and the challenges of systemic drug reactions. Professor Wang talks about his research into predicting which patients will experience systemic drug reactions based on researc…

1
Treatment of Drug Resistant TB 34:09

1+ y ago34:09

34:09

Drug Resistant TB is a growing problem with some exciting advances over the past decade. With the recent Rapid Communication from the WHO and the advent of the B-PALMS regimen, drug resistant TB is a changing and exciting field of tuberculosis around the world. In this episode Professor Greg Fox from the University of Sydney speaks with Dr Jack Cal…

1
Vaccination in Tuberculosis 24:03

1+ y ago24:03

24:03

BCG has long been the only widely used vaccination strategy since it's initial use over 100 years ago. In high TB burden settings it is still recommended in children to protect against disseminated disease though the lasting protection offered by BCG vaccination has been poor at best. Today, Emeritus Professor Warwick Britton AO FAHMS from the Cent…

1
Ethical Issues in Tuberculosis 38:26

2y ago38:26

38:26

How does stigma impact treatment in tuberculosis? Has the COVID-19 pandemic enabled high income countries to commiserate with lower middle income countries who have high infectious disease burden? Are antimicrobials impacting the way some countries treat tuberculosis? Dr Paul Mason explores these questions while addressing other ethical issues in t…

1
Child and Adolescent Tuberculosis 28:24

2+ y ago28:24

28:24

Tuberculosis is a global health priority and a major cause of child and adolescent morbidity and mortality. Approximately 1.5 million children and adolescents are infected with tuberculosis each year. Tuberculosis in children and adolescence is often overlooked by health providers and can be difficult to treat and diagnose. Professor Steve Graham w…

1
The TB Practecal Study 26:53

2+ y ago26:53

26:53

Philipp is the co-head of the Burnet Institute Tuberculosis Elimination and Implementation Science Group. He is an infectious diseases specialist with more than 15 years of extensive clinical and public health experience, and over 10 years’ experience in the management of TB/HIV programs. He has worked as a TB/HIV advisor, and supported program imp…

1
Rheumatoid Arthritis and Latent Tuberculosis Reactivation - Clinical Case 27:48

3y ago27:48

27:48

Dr Andrew Burke and Dr Ramdeep Bajwa discuss clinical cases consisting of rheumatoid arthritis, the risk of tuberculosis reactivation and management of tuberculosis.By Actnet

1
Tuberculosis Control 28:20

3+ y ago28:20

28:20

What are the broader issues for TB control at present? How has COVID-19 impacted TB programs? What are the longer term prospects for TB control over the coming decade in the post pandemic era? Dr James Trauer and Professor Guy Marks answer these questions and discuss the areas requiring focus. Guy Marks is a respiratory physician and epidemiologist…

1
Molecular Testing in Tuberculosis 37:46

3+ y ago37:46

37:46

Molecular testing in Tuberculosis (TB) is broad and complex. Dr Andrew Burke and Dr Chris Coulter discuss the utility/ advantages of Ultra GeneExpert, different types of line probe assays and WGS/ NGS in the future. Dr Chris Coulter uses his expertise to explain these diagnostic tools for physicians, nurses, policy makers and public health professi…

1
Active Case Finding 30:27

3+ y ago30:27

30:27

What are the issues with active case finding? What is the trajectory and the way forward to obtain tangible differences in reducing TB globally? Professor Greg Fox and Dr Kavi Velen explore the answers to these questions and discuss why active case finding has not shown the anticipated level of progress predicted by the literature and the World Hea…

1
Tuberculosis Clinical Presentation 24:32

4y ago24:32

24:32

TB clinical presentation is complex. This is because TB may involve any tissue or organ, the severity of symptoms range from none to overwhelming, the tempo of the illness ranges from indolent to rapid, symptoms/ findings may be local or systematic, the presentation varies in immunocompromised and diagnostic tests such as TST or IGRA cannot provide…

1
The similarities and differences between COVID-19 and TB 31:37

4y ago31:37

31:37

COVID-19 and TB respiratory illnesses share both significant similarities and differences. At first glance, the viruses appear to be very different infections. However, perhaps one of the most important similarities is how the infections affect communities epidemiologically. Dr James Trauer and Dr Anna Coussens discuss the similarities and differen…

1
Paediatric Tuberculoisis 27:29

4y ago27:29

27:29

TB is in the global top 10 leading causes of death in children under five. Migration and international travel have caused TB rates to have risen even in typically low burden countries. A child with infected TB may not have active disease. As a result, children are at risk of becoming reservoirs where TB may become reactivated in adulthood thus fuel…

1
Post TB Lung Disease 24:56

4y ago24:56

24:56

Post TB lung disease is am important yet, difficult area to research. The number of those affected by post TB lung disease is unknown however, is thought to be significant. Additionally, those affected by post TB lung disease are associated with an increased burden of symptoms along with an economic cost. Dr Anthony Bryne discusses the importance o…

1
Patient Support and TB Treatment Adherence 25:44

4+ y ago25:44

25:44

Dr Kerry Viney from the Australian National University and Mr Neil Heron a Clinical Nurse Consultant from NSW Health TB Program, discuss the controversial yet, important topic on patient TB treatment adherence.By Actnet

1
Latent Tuberculosis Infection 29:35

4+ y ago29:35

29:35

What is latent tuberculosis infection? How does it affect patients? How should we treat it? These questions are addressed by Associate Professor Justin Denholm and Dr James Trauer in this podcast. Associate Professor Justin Denholm is the Medical Director of the Victorian Tuberculosis Program. Justin is an infectious diseases physician and ethicist…

Podcasts Worth a Listen

Actnet Podcasts

Podcasts Worth a Listen

1
The TBPod

Actnet

1
Frontiers in Clinical Tuberculosis Microbiology - New TBI Diagnostics with Prof Martineau 30:08

1
MTBVAC - one of the most promising new TB Vaccines with Dr Carlos Martín Montañés 42:58

1
TB Contact Tracing and Building Research in TB with Prof Philip Hill 30:13

1
END-TB Trial with Dr Guglielmetti 46:27

1
Tuberculosis Diagnostics & Emerging Technologies with Dr Morten Ruhwald 24:14

1
Tuberculosis Nursing Challenges in Australia's Northern Territory with Dr Chris Lowbridge 36:21

1
Drug Development with Dr Clifton Barry 42:02

1
Where are we with TB Vaccines - with Prof Triccas 40:33

1
What does TB Elimination mean? 40:43

1
Papua New Guinean Challenges of TB in Pregnancy 34:15

1
How WGS is shaping the public health in Australia 40:32

1
Discovery of tuberculosis - the life of Robert Koch 48:22

1
Differentiating TB from Sarcoid 32:03

1
Mind the Gap - Update on Global TB Goals 45:13

1
Understanding TB Diagnostic Tests 40:07

1
Understanding TB Screening Tests 32:50

1
Tuberculosis Modelling 30:39

1
Therapeutic Drug Monitoring in TB 33:48

1
Predicting Side Effects in 3HP 18:09

1
Treatment of Drug Resistant TB 34:09

1
Vaccination in Tuberculosis 24:03

1
Ethical Issues in Tuberculosis 38:26

1
Child and Adolescent Tuberculosis 28:24

1
The TB Practecal Study 26:53

1
Rheumatoid Arthritis and Latent Tuberculosis Reactivation - Clinical Case 27:48

1
Tuberculosis Control 28:20

1
Molecular Testing in Tuberculosis 37:46

1
Active Case Finding 30:27

1
Tuberculosis Clinical Presentation 24:32

1
The similarities and differences between COVID-19 and TB 31:37

1
Paediatric Tuberculoisis 27:29

1
Post TB Lung Disease 24:56

1
Patient Support and TB Treatment Adherence 25:44

1
Latent Tuberculosis Infection 29:35

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