Welcome to the "Beyond Limits" podcast with Justin Nyoni, where we explore the depths of personal development and leadership. Join us as we dive into the world of self-improvement, pushing past our limitations and reaching for greatness. Through audio recording of the world's greatest thinkers, conversations with experts and thought leaders in the field, we uncover valuable insights and practical tools to help you unleash your potential and achieve your goals. Whether you're an aspiring lead ...
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Exploring all things genetics. Dr Patrick Short, University of Cambridge alumnus and CEO of Sano Genetics, analyses the science, interviews the experts, and discusses the latest findings and breakthroughs in genetic research. To find out more about Sano Genetics and its mission to accelerate the future of precision medicine visit: www.sanogenetics.com
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Liquor, bars, cocktails: the people and companies who make them, sell them and drink them, plus everything & everyone in-between, with your host, globetrotting spirits guy and escaped bartender, Philip Duff.
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Interviewing top real estate professionals, gathering insight, inspiration, systems, tactics, and actionable business advice from the best and brightest minds industry wide!
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Welcome to Velocity Clients, where you learn and then remove the L. We go over history of mankind and find patterns that you can incorporate.
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The Authentic German Learning Podcast: Deutsch lernen wie ein Baby | Learn German online | Personal Development
Mark Rösler: deutscher Muttersprachler & Deutschlehrer, Genießer des Lebens und Philosoph
Learn German like a baby would by listening to the language and getting a "feel" for it. We're not only learning German here though: We are passionate about personal development of all kinds. Our motto: Improve your German. Improve your life. Listen to the podcast and let the German language wash over you, like music. Lerne Deutsch wie ein Baby, indem du der Sprache zuhörst und ein "Gefühl" für sie bekommst. Wir lernen hier aber nicht nur Deutsch: Persönliche Entwicklung jeder Art ist unsere ...
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EP 159: Engineering macrophages to tackle rare disease with Noam Baumatz of Noga Therapeutics
44:17
44:17
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0:00 Intro to The Genetics Podcast 01:00 Welcome to Noam and discussion of his motivation to drive rare disease forward 03:00 Noam’s daughter Noga’s experience of rare disease, including an 8 to 12 month journey to diagnosis 05:10 How the experience of his daughter receiving a genetic diagnosis motivated Noam to take change into his own hands 10:12…
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#87, Emily LaRuffa, New York hospitality veteran and founder of Oracle Hospitality Consultants
2:34:50
2:34:50
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Emily LaRuffa has scaled the dizzy heights of Manhattan hospitality business, from bartending to managing and being a GM at every kind of NY joint from rock 'n' roll bars in Hell's Kitchen to the five-star luxury of Loews Hotel, The Baccarat, Major Food Group (and cheerful pirate Brian Miller)'s The Polynesian, and Danny Meyer's Union Square Hospit…
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EP 158: Research Roundup with Dr Veera: Discoveries in neurogenetics, evolution, cardiac arrhythmias, and more!
1:11:31
1:11:31
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0:00 Invitation to The Genetics Podcast meetup 1:30 Intro to The Genetics Podcast 2:30 Welcome to Veera 3:20 The evolution on skin color in humans and their ancestors: Discussion on how a retrotransposon—often called a "jumping gene"—within the ASIP gene (agouti signaling protein) influenced the evolution of skin pigmentation in humans and their an…
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#86, Alice Lascelles, award-winning drinks writer and author of “The Martini: The Ultimate Guide To A Cocktail Icon”
1:03:48
1:03:48
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Alice, an old friend from way back when, is one of the best drinks writers based in the UK, has won multiple awards for her writing about spirits, wine, beer, cocktails and bars, is often to be found on UK radio & TV, and just published her new book "The Martini: The Ultimate Guide to a Cocktail Icon", so we sat down over a martini (or in my case, …
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EP 157: Bridging genomics, business, and equity in healthcare access with Mark Taylor of LGC Group
35:40
35:40
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0:00 Invitation to The Genetics Podcast meet up 1:30 Intro to The Genetics Podcast 2:25 Welcome to Mark 3:10 Introduction to the National Institute for Health Research (NIHR) 4:05 Mark’s roles with the NIHR in strategic partnerships 7:35 Challenges patients face in accessing NHS resources and the NIHR’s efforts to streamline availability 13:25 How …
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EP 156: The Genetics Podcast In-Person Event!
1:32
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We hope you will join us at our first (of hopefully many!) in-person podcast event! Please use this link to sign up.By Sano Genetics
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#85, Kara Newman, award-winning drinks writer & author, New York City
1:40:10
1:40:10
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Kara defected to writing about spirits, cocktails and bars after starting out writing about matters financial, and finance's loss is cocktail's gain! A New York native and friend, Kara has written seven spirits- and cocktail-related books as well as her newest venture, The Cocktail Cabinet, decks of beautiful playing cards themed around a particula…
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EP 155: Adeno-associated virus as a delivery vector for genetic eye disease treatment, with Paul Wille of Abeona Therapeutics
32:18
32:18
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0:00 Invitation to our first in-person podcast event 1:30 Intro to The Genetics Podcast 2:20 Welcome to Paul 2:53 Adeno-associated virus (AAV) biology and its advantages over other viral vectors 5:20 The gene therapy landscape and options for therapy development and delivery 6:49 The limitations of working with AAV to deliver gene therapy, includin…
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#84, Chris Cardone, sober advocate, founder Continuous Beverage Solutions, Diageo World Class USA winner, NYC (flair) bartender & mixologist
2:13:10
2:13:10
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I've known New York (well, Long Island) native Chris for over two decades, since we met at a flair bartending contest in the Cayman Islands, and he's maintained his rep as a flair bartender while becoming an accomplished mixologist as well, getting sober, winning Diageo World Class USA in 2017, crafting the Via Carota range of bottled cocktails and…
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EP 154: Pioneering early disease detection through wearable devices and regular monitoring with Dr. Mike Snyder
41:03
41:03
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0:00 Introduction 1:00 Overview of Mike’s background and contributions to genomics and preventative medicine, as well as how he first became interested in deep data collection for health monitoring 4:20 The use of various tools, including smartwatches, blood tests, genetic testing, and more, to create a comprehensive view of an individual’s health …
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EP 153: How genomics is re-writing the taxonomy of disease with Lon Cardon, President and CEO of The Jackson Laboratory
40:25
40:25
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0:00 Intro to The Genetics Podcast 01:00 Welcome to Lon 01:51 Lon’s involvement in the very first GWAS and what drew him to large-scale genomics research 03:32 Was moving away from candidate genes towards GWAS and data sharing initially a controversial idea? 05:25 What Lon believes has driven collaboration and data sharing within research communiti…
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#83, Iain McPherson, owner, Panda & Sons, Hoot the Redeemer, Nauticus, Edinburgh.
2:02:04
2:02:04
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The Cocktail Panda himself comes on The Philip Duff Show! I've known Iain for years - he entered the G'Vin Gin Connoisseur Program which I used to run - and he's built a mini bar empire in Edinburgh so it was time to catch up on his adventures guest bartending for his uncle in Korea, celeb liquor, how he got his start in the bar business and what h…
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EP 152: Unlocking the secrets of gene regulation with Nadav Ahituv, Director of the Institute of Human Genetics at UCSF
42:40
42:40
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01:15 - Introductions 02:02 - How our understanding of the non-coding genome has evolved throughout Nadav’s career 04:56 - Our current understanding of non-coding genome grammar 07:40 - Is there a missing piece to the common variant, common disease paradigm? 10:25 - Introducing ultraconserved elements (UCEs) and human accelerated regions (HARs) 12:…
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EP 151: Understanding cell ageing and its role in disease with Marco Quarta Co-founder and CEO of Rubedo Life Sciences
42:36
42:36
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0:00 Intro to The Genetics Podcast 01:00 Welcome to Marco 02:00 The areas Marco focused on during his academic career and what motivated him to found his first company 03:18 How our understanding of ageing has changed over the past two decades and some of the current big questions in ageing biology 06:01 How to get a clearer picture of the ageing p…
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#82, Marshall Minaya, beverage director Valerie, Madame George and Lolita, New York City.
1:49:15
1:49:15
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Marshall - and the three top-notch places he runs the beverage programs for, Valerie, Lolita and Madame George - is one of Manhattan's best-kept secrets. If you come to New York, I'll take you to one of these places (or all three, as they're conveniently located right next door to one another), and I guarantee you'll be blown away by the quality of…
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EP 150: Cracking the biological code of aging with Martin Borch Jensen, Co-Founder and Chief Scientific Officer at Gordian Biotechnology
44:21
44:21
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0:00 Intro to The Genetics Podcast 01:00 Welcome to Martin 01:35 How a particularly large Indian meal resulted in a book about intermittent fasting and the biology of ageing 05:10 The biological mechanisms behind intermittent fasting, and whether it’s been established to extend life expectancy in humans. 10:13 What we know (and what we don’t) about…
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#288: Real Estate Titans with Greg Fowler featuring special guest, Mark Davis Follow us on Facebook: @RealEstateTitansLive Watch this episode on YouTube: Real Estate Titans Channel Greg Fowler on Instagram: @gregfowlerco Sponsored by Lion Bolt Media. https://www.lionboltmedia.com/By Greg Fowler
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#81, Tim McKirdy, managing editor, VinePair, recovering chef, host of the Cocktail College podcast
2:33:23
2:33:23
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Myself and Tim have been threatening each other with a podcast taping for over a year, and we finally found time to sit down, beverages to hand, and make it happen! (This is a satisfyingly lengthy episode, clocking in at over 2.5 hours, and we'll do more of such chat fests in the future, too). We talk about Tim's path into the industry as a cook an…
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EP 149: Sequencing 33 million samples to support the UK’s COVID-19 response with Tony Cox, CEO of UK Biocentre
34:16
34:16
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0:00 Intro to The Genetics Podcast 01:00 Welcome to Tony 02:00 What Tony was expecting going into the role of CEO at UK Biocentre, and how the COVID-19 pandemic changed his plans 03:38 Receiving a phone call from the UK government in March 2020 asking the UK Biocentre to stop all of its projects and focus on sequencing COVID-19 samples 05:12 The UK…
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#287: Real Estate Titans with Greg Fowler featuring special guest, Jimmy Dulin Follow us on Facebook: @RealEstateTitansLive Watch this episode on YouTube: Real Estate Titans Channel Greg Fowler on Instagram: @gregfowlerco Sponsored by Lion Bolt Media. https://www.lionboltmedia.com/By Greg Fowler
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#80 Simone Caporale, co-owner Sips & Sips Esencia (#1, W50BB 2023), Amaro Santoni, Canaima Gin, MUYU Liqueurs & The Art of Shaking
1:15:10
1:15:10
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Simone has come a long way since his Italian childhood in Como: while part of a legendary double-act with Alex Kratena, he led London's Artesian Bar to an unprecedented four #1 listings in World's 50 Best Bars. Simone's post-Artesian career is even more impressive: Sips, his Barcelona bar together with business partner Marc Alvarez, was crowned #1 …
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EP 148: Advancing veteran health through the Million Veteran Program with Dr. Mike Gaziano, professor of medicine at Harvard Medical School
35:13
35:13
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0:00 Intro 2:00 Mike’s career prior to the Million Veteran Program (MVP), how Mike got to work on MVP, and important milestones in the project's evolution 8:30 Future goals for the Million Veteran Program in expanding and diversifying the research cohort 11:00 The roles of various omics in advancing the project's development 14:30 The most meaningf…
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#79, Mark Pascal & Francis Schott, hosts of The Restaurant Guys podcast, owners of Stage Left Steak and Catherine Lombardi restaurants, New Brunswick, New Jersey
1:37:07
1:37:07
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Francis, and, later Mark, have been friends of mine for a long time; we must have bumped into one another in Manhattan or at a Tales of the Cocktail event in New Orleans, but it was our mutual friend Dale de Groff who persuaded me to make the trek out to NJ to see their restaurants, which are incredibly successful and a mainstay of their community.…
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EP 147: From research to delivering precision medicine in the clinic with Scott Weiss, Professor of Medicine at Harvard University
37:19
37:19
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0:00 Intro to The Genetics Podcast 01:00 Welcome to Scott 01:55 Scott’s career highlights to date, ranging from epidemiology to the genetics of asthma and chronic obstructive pulmonary disease (COPD) 04:56 How and why Scott decided to transition into genetics 06:30 The advances in our understanding of the genetics of asthma and COPD over the past 2…
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#78 Erik Lorincz, owner Kwānt (London), Antique American Bar (Bratislava), BIRDY by Erik Lorincz bar tools, ex-head bartender The Savoy, former Diageo World Class global champion.
1:42:01
1:42:01
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Me and Erik go waaaaaay back, to when I taught a class on the IBA's elite John Whyte residential training course in Karlovy Vary, Czech Republic, before Erik moved to London to start his stratospheric ascent to the top of the bartending world. We sat down during Tales of the Cocktail to talk about all that: awards, scalpels vs. hammers, how cities …
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EP 146: The biology of aging with Austin Argentieri, Research Fellow at Harvard Medical School, Affiliate Member of the Broad Institute, and Research Fellow at Massachusetts General Hospital
43:05
43:05
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0:00 Intro to The Genetics Podcast 01:00 Welcome to Austin 01:42 What is aging and how should we think about it? 03:50 Discussion of Austin’s recent breakthrough paper on aging, including the questions he set out to answer, and the outcomes of the research 06:32 How Austin’s work focuses on using large-scale population proteomics data to create acc…
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#286: Real Estate Titans with Greg Fowler featuring special guest, Zachary Beach Follow us on Facebook: @RealEstateTitansLive Watch this episode on YouTube: Real Estate Titans Channel Greg Fowler on Instagram: @gregfowlerco Sponsored by Lion Bolt Media. https://www.lionboltmedia.com/By Greg Fowler
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#77 Simon Difford, founder Diffordsguide.com, creator Difford's Easy Jigger, chronicler of the Second Cocktail Golden Age
1:42:21
1:42:21
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Simon's been a mate since the late 1990s, when he created CLASS (standing for Cocktail Liqueur And Speciality Spirit) magazine, the print forerunner of Difford's Guide and, in a pre-Internet world, just about the only way to learn about the revolution in cocktails that began sweeping London in the mid-1990s, which we both agree dates to the opening…
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EP 145: Navigating rare disease drug development regulations with Daniel O’Connor
39:12
39:12
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0:00 Intro to The Genetics Podcast 01:00 Welcome to Daniel 02:04 Defining rare disease in the age of personalized medicine 04:57 Key touchpoints with the Medicines and Healthcare products Regulatory Agency (MHRA) when developing a new medicine 09:27 Improvements over the course of Daniel’s career when it comes to incentivizing and making the path t…
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#285: Real Estate Titans with Greg Fowler featuring special guest, Lisa Lippman Follow us on Facebook: @RealEstateTitansLive Watch this episode on YouTube: Real Estate Titans Channel Greg Fowler on Instagram: @gregfowlerco Sponsored by Lion Bolt Media. https://www.lionboltmedia.com/By Greg Fowler
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#76, Natasha Bahrami, The Gin Girl, The Gin Room (St. Louis, Missouri), Gin World festivals (everywhere), member The Gin Guild
1:19:14
1:19:14
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I've known Natasha for ages and it's no exaggeration to say she's changed the landscape of gin consumption in her native Missouri, and indeed in the wider USA as well. Much as Julio Bermejo built a dedicated band of fanatics drinking 100% Blue Agave tequila at Tommy's, a suburb of San Francisco, Natasha did the same with gin, in her family's restau…
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EP 144: Research Roundup with Dr. Veera: breakthroughs in developmental disorders, Parkinson's, SLE, and Alzheimer's
56:48
56:48
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0:00 Introduction 1:40 A recurrent de novo mutation in a noncoding region of a small nucleolar RNA gene that has been identified as one of the most common causes of neurodevelopmental disorders This pathogenic variant escaped notice for years because it was not located in a protein coding region of the genome It now shows potential as a target for …
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#75 Zev Glesta, spirits specialist Sotheby's New York, ex-bartender at The Modern, The Fat Duck/Dinner
1:47:20
1:47:20
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Zev's had one of the most interesting career arcs of any bartender I know, but when we finally sat down to tape an episode, it turned out to have even more twists and turns than I thought! From Brooklyn to Melbourne to Montreal and back to NY, and from bartending for Heston Blumenthal Down Under to manning the shakers in the Meyerverse* that is Uni…
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EP 143: Harnessing human data in drug development with Jakob Steinfeldt, Co-Founder and Chief Scientific Officer at Pheiron
36:17
36:17
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0:00 Intro to The Genetics Podcast 01:00 Welcome to Jakob and background on Pheiron 02:14 What made Jakob decide to start Pheiron, what the company does, and how his scientific background inspired him to found a start-up 5:24 Jakob’s excitement and inspiration around the power and potential of machine learning 07:07 Cardiology and heart failure as …
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#74, Anna Sebastian, UK-based hospitality consultant, founder of #CelebrateHer, ending homelessness with @underonesky
2:06:58
2:06:58
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Anna is brilliant and this episode - taped partly in a hotel lobby in London, and then on Zoom - is just like having a drink with her, which is always great. She's not afraid to say the things others won't, and her goal is to elevate anyone she works with, and especially to make bars better and get more women to embrace hospitality as a career opti…
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EP 142: From genome to bedside: How genetics is transforming modern medical practice with Dr. Andrea Gropman
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42:45
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0:00 Introduction 1:40 Andrea’s background and how she got into the field of genetics, neuroimaging, and metabolic disorders 4:00 Insights into Andrea’s clinical practice, including the diverse families and patients she serves and her approach to clinical decision-making 6:30 How genetics and genomics have changed the diagnostic journey in the last…
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#73, Ago Perrone, Director of Mixology, The Connaught, co-author, The Connaught Bar book
1:20:23
1:20:23
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Well, I've know Agostino since he was a fresh-faced young buck at Montgomery Place, one of London's best cocktail bars back in the day. I remember when he moved to take the reins at the Connaught when it reopened, and the dream opening duo that was him and Erik Lorincz. In the sixteen years since, Ago built a core around him with stunning professio…
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EP 141: Bringing genomics to the clinic with Lori Orlando, Associate Prof at Duke University
43:24
43:24
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0:00 Intro to The Genetics Podcast 01:00 Welcome to Lori Orlando 03:00 Lori’s career: From mathematical modelling to genetics and family history 05:11 The study that revealed 20% of the general population is at a higher risk of disease than average and needs preventative care 07:36 The first five diseases that Lori started analysing through informa…
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#72 Benji Cavagna, partner, Farmily Bars Group (Milan), co-founder, Bitter Fusetti
1:36:19
1:36:19
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Benji (whose actual name is Fabio), is a friend, and a tremendous host even among his fellow Italian bartenders, which is really saying something. After studing philosophy and being a professional soccer player (!), Benji went into bartending and is now a partner in the Farmily hospitality group that includes 1930 Bar, MAG Cafe and Tripstillery, al…
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EP 140: The future of Electronic Health Records and data analysis with Ben Goldacre
52:51
52:51
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0:00 Intro to The Genetics Podcast 1:00 Welcome to Ben Goldacre 02:22 Ben’s open data projects at the Bennett Institute and the challenges they aim to tackle 04:03 Using Electronic Health Records (EHR) to help the National Health Service improve care 06:18 The importance of software development within healthcare data and how to manage salary scales…
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#71, David Thomas Tao, Kentuckian, whisky writer, fitness commentator (!), voiceover actor, theatre investor
2:26:31
2:26:31
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I kept bumping into David at events (like Philip Duff Show stalwart Tony Sach's regular get-togethers for writers and other waifs and strays) and he was always good fun to chat with, so me and him sat down in a shady spot inside Central Park* on a hot-as-balls day, on camp chairs, with a nearby wheelie cooler bag full of ice cold Negra Modelo beers…
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EP 139: Rare disease breakthroughs using tRNA with Michelle Werner, CEO of Alltrna and CEO-Partner of Flagship Pioneering
44:42
44:42
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0:00 Intro to The Genetics Podcast. 01:00 Welcome to Michelle. 02:00 Sstop codon diseases and how are they characterised 03:45 Diseases caused by premature stop codons in haploinsufficient genes. 04:35 The role of transfer RNA technology in finding solutions for premature stop codon diseases. 06:16 How Alltrna is engineering tRNAs which can bind to…
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#70, Gegam Kazarian, founder Yerevan Cocktail Week, Magika Cordials, champion bartender, renaisssance man
1:27:50
1:27:50
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What to say about my old mate Gegam Kazarian? In his native Armenia, he studied biochemistry, then floral design, then silversmithing, started bartending, followed his passion for Spanish classical guitar by emigrating to Spain, started several bars and a mixology lab, won the Havana Club Rum European championships, the G'Vine Gin Connoisseur Progr…
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#284: Real Estate Titans with Greg Fowler featuring special guest, Dani Hampton Follow us on Facebook: @RealEstateTitansLive Watch this episode on YouTube: Real Estate Titans Channel Greg Fowler on Instagram: @gregfowlerco Sponsored by Lion Bolt Media. https://www.lionboltmedia.com/By Greg Fowler
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#69 (nice!), Shannon Mustipher, tropical drinks guru, bartender, author, consultant
1:24:19
1:24:19
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Shannon, a Charleston native, is a powerhouse: an artist who left art due to its restrictions, a New York City bartender who championed rum when no-one cared about it (spoiler: a lot of people still don't care), the award-winning author of "Tiki: Modern Tropical Cocktails" and a consultant and ambassador for brands including Denizen Rum, Privateer …
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EP 138: Personalised medicine using microbiome models with Dr. Almut Heinken
40:22
40:22
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0:00 Introduction 1:45 Almut’s research experience, including two recent publications on genome-scale metabolic reconstruction human microorganisms Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple…
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#68 Jim Meehan, award-winning mixologist, bartender, author and consultant
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Me and Jim met in 2006, when he entered the Bols 200 contest I organised, and I dropped by Pegu Club to see him next time I was in New York (I was living in Holland at the time). He went on to open PDT (Please Don't Tell) in 2007, which almost immediately became the most famous cocktail bar in the world (and also served the best hot dogs to be had …
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EP 137: Mavis Machirori on promoting equity, diversity, and social justice in genomics research
41:40
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0:00 Intro 1:30 Mavis’ career arc, from starting as a midwife to researching medical innovation and technology with an emphasis on advocacy and equity 7:00 Systemic issues that are easily overlooked in medical research and advancements Webinar: Participant Diversity: Increasing the Impact of Biomedical Research Webinar 10:00 Addressing Eurocentrici…
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#67, Robb Jones, owner, Meteor bar, Minneapolis
1:09:35
1:09:35
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Robb's been a mate for a long time - I think we met when he was a Tales of the Cocktail Cocktail Apprentice (CAP) - and the first event we ever did after I launched Old Duff Genever in Minnesota was at his bar, Meteor, which he opened in late 2019. Timing, eh! Robb and his business partners and staff weathered the madness of the 'rona, and recently…
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EP 136: Developments in ring chromosome 20 research and advocacy with Allison Watson
40:57
40:57
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0:00 Introduction 2:00 Allison’s personal journey to researching epilepsy and ring chromosome 20 syndrome 4:00 Biggest challenges families face with ring chromosome 20 syndrome 11:00 Incidence and prevalence of r(20) syndrome, and how we can improve data reliability 21:00 Applying next generation sequencing to r(20) syndrome gene research 29:00 Eng…
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