Best Breakthrough Institute Podcasts (2024)

1
Predetermined Change Control Plans, Part 2 57:41

1h ago57:41

57:41

In this Medtech Matters podcast episode of Mike on Medtech with Mike Drues, president of Vascular Sciences, we continue speaking on the topic of predetermined change control plans. Potential scenarios for their use are discussed, examples are provided, and role of PCCPs for manufacturing processes are explored. If you haven’t yet listened to Part 1…

1
Predetermined Change Control Plans, Part 1 48:29

16m ago48:29

48:29

In this Medtech Matters podcast episode of Mike on Medtech with Mike Drues, president of Vascular Sciences, we examine the FDA’s recent guidance documents regarding predetermined change control plans (PCCP). The first guidance addresses PCCPs for artificial intelligence (AI) and/or machine learning (ML) based devices (click here to hear an earlier …

1
#116: Salesforce and HubSpot AI Launches, Enterprise AI Agents & First Major Hollywood Studio Embraces AI 58:14

21m ago58:14

58:14

After major conferences with Salesforce and HubSpot this week, it’s clear that companies are really getting on board with AI agents. Join Mike and Paul as they chat about the ups and downs of these AI agents and what they mean for the future of work. And that’s not all—our hosts also talk about Runway’s latest partnership with Lionsgate, Sam Altman…

1
EP 152: Unlocking the secrets of gene regulation with Nadav Ahituv, Director of the Institute of Human Genetics at UCSF 42:40

7h ago42:40

42:40

01:15 - Introductions 02:02 - How our understanding of the non-coding genome has evolved throughout Nadav’s career 04:56 - Our current understanding of non-coding genome grammar 07:40 - Is there a missing piece to the common variant, common disease paradigm? 10:25 - Introducing ultraconserved elements (UCEs) and human accelerated regions (HARs) 12:…

1
#115: OpenAI o1, Google’s Insane NotebookLM Update, MAICON 2024 & OpenAI’s $150B Valuation 1:12:38

7d ago1:12:38

1:12:38

Our annual gathering, MAICON (Marketing AI Conference) has wrapped, and Paul and Mike dive into a bit of the key event takeaways, including an impromptu closing keynote breaking down the Strawberry (OpenAI o1) launch. Also, OpenAI’s $150B valuation and Google’s Notebook LM update make for an exciting episode! 00:04:56 — OpenAI o1/Strawberry 00:24:4…

1
EP 151: Understanding cell ageing and its role in disease with Marco Quarta Co-founder and CEO of Rubedo Life Sciences 42:36

20h ago42:36

42:36

0:00 Intro to The Genetics Podcast 01:00 Welcome to Marco 02:00 The areas Marco focused on during his academic career and what motivated him to found his first company 03:18 How our understanding of ageing has changed over the past two decades and some of the current big questions in ageing biology 06:01 How to get a clearer picture of the ageing p…

1
#114: ProblemsGPT, The ROI of Generative AI, Andrej Karpathy on the Road to Automated Intelligence & Ilya Sutskever Raises $1B 1:08:13

3d ago1:08:13

1:08:13

It’s an exciting week here in Cleveland as MAICON kicks off, and we have just as exciting AI news and updates to share. Join Mike and Paul as they unveil SmarterX's newest tool, ProblemsGPT. The guys also break down use cases of Generative AI productivity benefits, plus, hear Karpathy's insights on the journey toward automated intelligence. 00:05:1…

1
EP 150: Cracking the biological code of aging with Martin Borch Jensen, Co-Founder and Chief Scientific Officer at Gordian Biotechnology 44:21

8d ago44:21

44:21

0:00 Intro to The Genetics Podcast 01:00 Welcome to Martin 01:35 How a particularly large Indian meal resulted in a book about intermittent fasting and the biology of ageing 05:10 The biological mechanisms behind intermittent fasting, and whether it’s been established to extend life expectancy in humans. 10:13 What we know (and what we don’t) about…

1
#113: OpenAI’s Upcoming “Strawberry” Launch and $100B Valuation, SB-1047 Passes, Oprah Gets Into AI & Viggle Scrapes YouTube Videos 1:08:31

20d ago1:08:31

1:08:31

Less than a week remains until MAICON 2024, and the AI news keeps rolling in. Join Paul Roetzer and Mike Kaput as they look into the recent developments at OpenAI, including insights on their "Strawberry" system and their latest fundraising efforts. In our final main topic, listen in to our hosts as they dissect the implications of California's con…

1
Opioids in America: A Crisis Without End (with Jennifer Sharpe Potter, PhD, MPH, Vice President for Research; Professor of Psychiatry and Behavioral Sciences at the University of Texas Health San Antonio ... 31:48

14d ago31:48

31:48

In this episode of INNOVATORS, Dr. Jennifer Potter's talk offers an in-depth analysis of the enduring and deadly opioid crisis in America, exploring the factors that have sustained this epidemic for decades and assessing recent developments in overdose trends to understand their implications for the future. Originally from Canada, Dr. Potter earned…

1
What is a CAPA and How Do You Best Use It? 58:13

21d ago58:13

58:13

In this Medtech Matters podcast episode of Mike on Medtech with Mike Drues, president of Vascular Sciences, we’re focusing in on a regulatory piece that’s been mentioned numerous times with regard to other topics we’ve discussed. This episode is focused on CAPA or corrective and preventive action. We’re digging into the CAPA, what it is, its purpos…

1
EP 149: Sequencing 33 million samples to support the UK’s COVID-19 response with Tony Cox, CEO of UK Biocentre 34:16

15d ago34:16

34:16

0:00 Intro to The Genetics Podcast 01:00 Welcome to Tony 02:00 What Tony was expecting going into the role of CEO at UK Biocentre, and how the COVID-19 pandemic changed his plans 03:38 Receiving a phone call from the UK government in March 2020 asking the UK Biocentre to stop all of its projects and focus on sequencing COVID-19 samples 05:12 The UK…

1
#112: CampaignsGPT, Top 100 GenAI Tools, AI Agent Hype “Justified 100%” Says Cohere CEO & Amazon Saves “4,500 Developer Years” with AI 1:10:30

28d ago1:10:30

1:10:30

From AI assistants pulling pranks to companies taking bold anti-AI stances, join our hosts as they navigate the wild world of AI innovation, controversy, and Rick Astley-inspired shenanigans. This week, Paul Roetzer and Mike Kaput unveil CampaignsGPT, a cutting-edge tool from SmarterX for analyzing AI's impact on campaign tasks. Our hosts also exam…

1
EP 148: Advancing veteran health through the Million Veteran Program with Dr. Mike Gaziano, professor of medicine at Harvard Medical School 35:13

28d ago35:13

35:13

0:00 Intro 2:00 Mike’s career prior to the Million Veteran Program (MVP), how Mike got to work on MVP, and important milestones in the project's evolution 8:30 Future goals for the Million Veteran Program in expanding and diversifying the research cohort 11:00 The roles of various omics in advancing the project's development 14:30 The most meaningf…

1
You Got a 483 from the FDA. Now what? 58:43

29d ago58:43

58:43

In this Medtech Matters podcast episode of Mike on Medtech with Mike Drues, president of Vascular Sciences, we’re discussing what the process should be for a company once they receive a 483 or warning letter from the FDA. Best practices, first steps to take, who is responsible, and potential strategies for avoiding them are shared. Specifically, th…

1
#111: Grok-2 Controversy, Demis Hassabis: AI Is “Unreasonably Effective,” AI in Schools & Ex-Google CEO Says AI Can Steal IP 1:15:03

24d ago1:15:03

1:15:03

It’s that time of year again and as students head back to school, they're not just packing pencils and notebooks anymore… they're bringing AI. Join our hosts, Paul Roetzer and Mike Kaput, as they discuss the complexities of AI in education as the new school year begins, the recent Grok 2 update from Elon Musk's xAI, and the return of Google DeepMin…

1
EP 147: From research to delivering precision medicine in the clinic with Scott Weiss, Professor of Medicine at Harvard University 37:19

1M ago37:19

37:19

0:00 Intro to The Genetics Podcast 01:00 Welcome to Scott 01:55 Scott’s career highlights to date, ranging from epidemiology to the genetics of asthma and chronic obstructive pulmonary disease (COPD) 04:56 How and why Scott decided to transition into genetics 06:30 The advances in our understanding of the genetics of asthma and COPD over the past 2…

1
#110: OpenAI’s Secret Project “Strawberry” Mystery Grows, JobsGPT, GPT-4o Dangers, Groq Funding, Figure 02 Robot, YouTube AI Class Action Suit & Flux 1:18:19

1M ago1:18:19

1:18:19

We have had our minds on strawberry fields this week with all the latest happenings at OpenAI. Join our hosts as they discuss OpenAI’s secret project “Strawberry” and OpenAI's leadership changes, including Greg Brockman's sabbatical and John Schulman's move to Anthropic. They'll explore JobsGPT, Paul Roetzer's tool for understanding AI's impact on …

1
#109: 2024 State of Marketing AI Report Findings & Top AI Questions Answered 1:16:01

2M ago1:16:01

1:16:01

In this special edition episode of The Artificial Intelligence Show, we are jumping into the 2024 State of Marketing AI Report. Join us as we recap the top 10 key findings from our comprehensive report. With insights collected from almost 1,800 respondents between March and July 2024, this fourth-annual report offers a detailed look at the role of …

1
EP 146: The biology of aging with Austin Argentieri, Research Fellow at Harvard Medical School, Affiliate Member of the Broad Institute, and Research Fellow at Massachusetts General Hospital 43:05

1M ago43:05

43:05

0:00 Intro to The Genetics Podcast 01:00 Welcome to Austin 01:42 What is aging and how should we think about it? 03:50 Discussion of Austin’s recent breakthrough paper on aging, including the questions he set out to answer, and the outcomes of the research 06:32 How Austin’s work focuses on using large-scale population proteomics data to create acc…

1
#108: OpenAI Voice, AI Cloud Wars, Microsoft’s AI Revenue, Meta Earnings and AI, Perplexity Publishers Program & SB-1047 California AI Bill 1:08:38

2M ago1:08:38

1:08:38

ChatGPT finds its voice! Join Paul Roetzer and Mike Kaput as they discuss OpenAI's cautious rollout of voice features for ChatGPT, assess Chris Miller's insights on the emerging "cloud war," and examine Microsoft's latest AI-driven financial results. Our hosts also touch on Perplexity’s publishers program, concerns behind California’s AI Bill SB-10…

1
EP 145: Navigating rare disease drug development regulations with Daniel O’Connor 39:12

2M ago39:12

39:12

0:00 Intro to The Genetics Podcast 01:00 Welcome to Daniel 02:04 Defining rare disease in the age of personalized medicine 04:57 Key touchpoints with the Medicines and Healthcare products Regulatory Agency (MHRA) when developing a new medicine 09:27 Improvements over the course of Daniel’s career when it comes to incentivizing and making the path t…

1
#107: Llama 3.1, Runway Steals YouTube Videos, Is There an AI Bubble?, DeepMind AI Math Breakthrough, Altman Op-Ed & SearchGPT 1:15:20

2M ago1:15:20

1:15:20

AI models are getting more powerful, but they are also dealing with some big ethical and financial hurdles. Join Paul Roetzer and Mike Kaput as they unpack Meta's release of Llama 3.1, dive into the controversy surrounding Runway's AI training practices, and examine the potential AI bubble looming over the industry. Plus, take a look into the lates…

1
EP 144: Research Roundup with Dr. Veera: breakthroughs in developmental disorders, Parkinson's, SLE, and Alzheimer's 56:48

2M ago56:48

56:48

0:00 Introduction 1:40 A recurrent de novo mutation in a noncoding region of a small nucleolar RNA gene that has been identified as one of the most common causes of neurodevelopmental disorders This pathogenic variant escaped notice for years because it was not located in a protein coding region of the genome It now shows potential as a target for …

1
#106: Enterprise AI Adoption, GPT-4o Mini, New Research on Prompting, OpenAI “Strawberry,” & AI’s Impact on the Crowdstrike Outage 1:10:43

2M ago1:10:43

1:10:43

Join our hosts as they unpack Chevron CIO Bill Braun's candid insights on the challenges of implementing AI in large corporations, explore OpenAI's latest GPT-4o mini model, and discuss the latest findings in prompting research. Plus, get the latest on Apple’s AI training data, AI’s impact on the Crowdstrike Outage, and the latest developments in A…

1
EP 143: Harnessing human data in drug development with Jakob Steinfeldt, Co-Founder and Chief Scientific Officer at Pheiron 36:17

2M ago36:17

36:17

0:00 Intro to The Genetics Podcast 01:00 Welcome to Jakob and background on Pheiron 02:14 What made Jakob decide to start Pheiron, what the company does, and how his scientific background inspired him to found a start-up 5:24 Jakob’s excitement and inspiration around the power and potential of machine learning 07:07 Cardiology and heart failure as …

1
#105: What Economists Get Wrong About AI, The AI Agent Landscape, and the Urgent Need for AI Literacy 1:06:01

2M ago1:06:01

1:06:01

Explore a future where AI could turn one cent of electricity into hundreds of dollars worth of top-tier professional work. Join our hosts as they unpack Carl Shulman's provocative insights on superintelligence, explore the rising world of AI agents, and examine the importance of AI literacy for all. Plus, take a look into the latest from OpenAI, Go…

1
Empowering Women: Shaping the Future with Marianne Williamson, Candidate for the 2024 Democratic Nomination 1:02:29

2M ago1:02:29

1:02:29

Get ready for an exciting episode! Join Denise, her daughter Nia Harrington, and Marianne Williamson, a candidate for the Democratic Nomination for President of the United States, as they delve into the power of women to shape the future. This thought-provoking conversation will challenge norms, inspire authenticity, and empower you to reclaim your…

1
EP 142: From genome to bedside: How genetics is transforming modern medical practice with Dr. Andrea Gropman 42:45

2M ago42:45

42:45

0:00 Introduction 1:40 Andrea’s background and how she got into the field of genetics, neuroimaging, and metabolic disorders 4:00 Insights into Andrea’s clinical practice, including the diverse families and patients she serves and her approach to clinical decision-making 6:30 How genetics and genomics have changed the diagnostic journey in the last…

1
#104: Top Consulting Firms Bet Big on AI, Why AI Isn’t Making Money, and Zoom CEO’s Bizarre Plan for AI Clones in Meetings 1:19:57

3M ago1:19:57

1:19:57

Join Paul and Mike as they discuss the surge in demand for AI consultants from major firms like BCG and McKinsey, explore the growing disconnect between AI investments and economic impact, and examine Zoom CEO’s Eric Yuan's ambitious plans for AI-driven digital twins in Zoom meetings. 00:03:31 — AI Consultants Success from the AI Boom 00:16:04 — AI…

1
EP 141: Bringing genomics to the clinic with Lori Orlando, Associate Prof at Duke University 43:24

2M ago43:24

43:24

0:00 Intro to The Genetics Podcast 01:00 Welcome to Lori Orlando 03:00 Lori’s career: From mathematical modelling to genetics and family history 05:11 The study that revealed 20% of the general population is at a higher risk of disease than average and needs preventative care 07:36 The first five diseases that Lori started analysing through informa…

1
#103: Claude 3.5, Suno and Udio Get Sued, OpenAI’s Ex-NSA Board Member, Ilya’s New Company, and Perplexity’s Woes 1:55:22

3M ago1:55:22

1:55:22

Paul and Mike are back! After a two-week hiatus, the longest episode of The Artificial Intelligence Show has dropped! Paul Roetzer and Mike Kaput discuss changes at the big companies: Anthropic’s Claude 3.5 is released, Perplexity, Suno, and Udio are in legal troubles, Ilya Sutskever, co-founder and former chief scientist at OpenAI, launches a new …

1
Windows to the Past and Future with the Sunners 50:31

3M ago50:31

50:31

Join us for a captivating episode of ABFI Table Talk as the Sunner family from Durabuilt Windows & Doors shares their personal and professional journey and how they built Durabuilt with grit, determination and passion. In Season 1, Episode 5, Joe, Harry, and Henny Sunner share their 29-year journey at Durabuilt and unpacking the layers of their exp…

1
EP 140: The future of Electronic Health Records and data analysis with Ben Goldacre 52:51

3M ago52:51

52:51

0:00 Intro to The Genetics Podcast 1:00 Welcome to Ben Goldacre 02:22 Ben’s open data projects at the Bennett Institute and the challenges they aim to tackle 04:03 Using Electronic Health Records (EHR) to help the National Health Service improve care 06:18 The importance of software development within healthcare data and how to manage salary scales…

1
EP 139: Rare disease breakthroughs using tRNA with Michelle Werner, CEO of Alltrna and CEO-Partner of Flagship Pioneering 44:42

3M ago44:42

44:42

0:00 Intro to The Genetics Podcast. 01:00 Welcome to Michelle. 02:00 Sstop codon diseases and how are they characterised 03:45 Diseases caused by premature stop codons in haploinsufficient genes. 04:35 The role of transfer RNA technology in finding solutions for premature stop codon diseases. 06:16 How Alltrna is engineering tRNAs which can bind to…

1
Revisiting Real-World Evidence 54:03

3M ago54:03

54:03

In this Medtech Matters podcast episode of Mike on Medtech with Mike Drues, president of Vascular Sciences, we’re revisiting real-world evidence (RWE), which is a topic that’s been getting some attention. So today, we’re going to look at what’s driving that attention and discuss the reasons behind it. We’ll also talk about how the FDA is seeking to…

1
Episode 3: Exploring Tick Myths and Realities in Australia 39:24

3M ago39:24

39:24

Any questions? Join us as we sit down with Stephen Doggett, a leading medical entomologist from Sydney, to explore the fascinating world of ticks. Stephen shares his journey from a nature-loving child to a renowned expert on ticks, discussing their ability to cause severe allergic reactions and paralysis. Learn about the proteins and toxins ticks i…

1
#102: Apple WWDC, Warnings of Superintelligence, and Adobe’s Controversial New Terms of Use 1:01:09

3M ago1:01:09

1:01:09

Some big company-driven controversies are at the front of this week's episode. Our hosts, Mike Kaput and Paul Roetzer, discuss Apple's introduction of "Apple Intelligence," a suite of generative AI features integrated into its devices, former OpenAI’s superalignment researcher Leopold Aschebrenner claims on the rapid approach of superintelligence a…

1
The Most Dangerous Devices to Hit the Market 40:42

3M ago40:42

40:42

In this Medtech Matters podcast episode of Mike on Medtech with Mike Drues, president of Vascular Sciences, we’re taking a look at several devices that unfortunately ended up being quite dangerous even though they made it to the market and were used by healthcare professionals. Some of these may have been brought up previously the Netflix documenta…

1
EP 138: Personalised medicine using microbiome models with Dr. Almut Heinken 40:22

3M ago40:22

40:22

0:00 Introduction 1:45 Almut’s research experience, including two recent publications on genome-scale metabolic reconstruction human microorganisms Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple…

1
#101: OpenAI’s Ex-Board Strikes Back, AI Job Fears, and Big Updates from Perplexity, Anthropic, and Showrunner 1:10:10

4M ago1:10:10

1:10:10

Following a week filled with controversy, drama, and updates in the AI world, hosts Mike and Paul are ready to bring you up to speed on all the latest happenings. Join us in Episode 101 of The Artificial Intelligence Show where we explore OpenAI's progress on GPT-5, the formation of its Safety and Security Committee, and criticism from former board…

1
EP 137: Mavis Machirori on promoting equity, diversity, and social justice in genomics research 41:40

4M ago41:40

41:40

0:00 Intro 1:30 Mavis’ career arc, from starting as a midwife to researching medical innovation and technology with an emphasis on advocacy and equity 7:00 Systemic issues that are easily overlooked in medical research and advancements Webinar: Participant Diversity: Increasing the Impact of Biomedical Research Webinar 10:00 Addressing Eurocentrici…

1
#100: Your Top AI Questions Answered: AI’s Impact on Business, Marketing, Jobs, Careers, Education and More 1:18:27

4M ago1:18:27

1:18:27

We've got a special bonus episode today, and it's all about celebrating our 100th episode! To mark this milestone, we have dedicated this episode to answering your questions. The Artificial Intelligence Show is much more than just a place for us to share content. It's our way of making sense of the AI world and putting it all into perspective. We a…

1
#99: Microsoft Build’s AI Announcement, OpenAI Scarlett Johansson Controversy, and Google’s Awful AI Overviews 1:10:36

4M ago1:10:36

1:10:36

In our first episode of the week, join Mike Kaput and Paul Roetzer as they explore Microsoft's new AI-infused PCs, Copilot AI agents, and Team Copilot. We also look into the controversy surrounding GPT-4o's Sky voice and its alleged similarity to Scarlett Johansson, and discuss Sundar Pichai's thoughts on AI's influence on search traffic and the ac…

1
EP 136: Developments in ring chromosome 20 research and advocacy with Allison Watson 40:57

4M ago40:57

40:57

0:00 Introduction 2:00 Allison’s personal journey to researching epilepsy and ring chromosome 20 syndrome 4:00 Biggest challenges families face with ring chromosome 20 syndrome 11:00 Incidence and prevalence of r(20) syndrome, and how we can improve data reliability 21:00 Applying next generation sequencing to r(20) syndrome gene research 29:00 Eng…

1
#98: Google I/O, GPT-4o, and Ilya Sutskever’s Surprise Departure from OpenAI 1:14:06

4M ago1:14:06

1:14:06

Get ready for a deep dive into Google's AI announcements from Google I/O 2024. Join Paul Roetzer and Mike Kaput as they explore Google's announcements, including Gemini 1.5 Pro's integration, Project Astra, Gems, and Veo. Episode 98 also examines the unveiling of OpenAI's latest cutting-edge model, GPT-4o, revolutionizing AI accessibility and the d…

1
EP 135: Integration of newborn sequencing programs into healthcare systems with Dr. Ingrid Holm 41:16

4M ago41:16

41:16

0:00 Introduction 1:30 Ingrid’s initial interests in genetics, paediatrics, and newborn screening 2:45 How the original BabySeq project, a pioneering newborn sequencing program got started, how it’s going, and the launch of BabySeq2 8:45 Lessons from BabySeq1 and goals for BabySeq2 10:30 Potential societal and long-term considerations for those inv…

1
#97: OpenAI’s Big Announcement, Google’s AI Roadmap, and Microsoft’s New AI Model MAI-1 50:27

4M ago50:27

50:27

Join us as we explore the latest AI developments, including OpenAI's anticipated announcement, Google's AI roadmap, and Microsoft's new in-house model, MAI-1. We break down the rumors, analyze the potential impact on the future of search and information access, and discuss what to expect from key players in the coming months. Don't miss this engagi…

1
EP 134: Prenatal genetic testing and the future of AI in genetic counselling with Kira Dineen, host of DNA Today 40:44

4M ago40:44

40:44

0:00 Introduction 1:00 The backstory of how Kira first started DNA Today in 2012, when she was still in high school! 3:30 Some of Kira’s favourite topics she has discussed on DNA Today, including the legacy of Henrietta Lacks, and the story of a Glee actress with down syndrome 10:00 Kira’s best practices for podcasting, from over 10 years of experi…

1
#96: Sam Altman Interview: “ChatGPT Is Mildly Embarrassing,” The Email Microsoft Doesn’t Want You to See, and Amazon Q 1:06:48

5M ago1:06:48

1:06:48

Sam Altman shares AI insights, Microsoft's rushed OpenAI decision comes to light, and Amazon Q hits the market. Join hosts Paul Roetzer and Mike Kaput as they explore Altman's thoughts on AI infrastructure, AGI dangers, and the gpt2-chatbot. Episode 96 also examines Microsoft's accelerated partnership with OpenAI, driven by fears of Google's AI cap…

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