Best Genome Editing Podcasts (2024)

1
Exploring Genome Editing Technologies in Drug Development 23:44

23h ago23:44

23:44

In this episode, host Dr. Katherine Bowen, is joined by Harriet Edwards, Associate Director in Regulatory Affairs, to explore the fascinating world of genome editing technologies. Together, they delve into the ethical considerations of editing somatic versus germline cells and trace the historical progression of these technologies from agriculture …

1
Extremophiles 1:00:53

3h ago1:00:53

1:00:53

Join us as we explore the fascinating world of extremophiles – the extraordinary organisms that thrive in the most inhospitable places on Earth. From the scorching hot springs to the icy depths of the Antarctic, these resilient creatures will blow your mind! What are extremophiles and why do they matter? What unique adaptations do they have and how…

1
EP 139: Rare disease breakthroughs using tRNA with Michelle Werner, CEO of Alltrna and CEO-Partner of Flagship Pioneering 44:42

12h ago44:42

44:42

0:00 Intro to The Genetics Podcast. 01:00 Welcome to Michelle. 02:00 Sstop codon diseases and how are they characterised 03:45 Diseases caused by premature stop codons in haploinsufficient genes. 04:35 The role of transfer RNA technology in finding solutions for premature stop codon diseases. 06:16 How Alltrna is engineering tRNAs which can bind to…

1
Special Feature - Pursuing Life Sciences Careers: Insights from Anderson MBA Students 50:07

21h ago50:07

50:07

To learn more about BCLA’s events and consulting visit https://www.bc-la.org/ To learn more about UCLA Anderson School of Management visit https://www.anderson.ucla.edu/ Follow our Instagram @insidebiotech for updates about episodes and upcoming guests! To learn more about BCLA’s events and consulting visit our website. Follow BCLA on LinkedIn…

1
Mysterious Mycology 1:05:46

6d ago1:05:46

1:05:46

Get ready to dive into the mysterious and marvellous world of Mycology (fungi) on this week's episode of The Information Entropy Podcast! Ever wondered what those mushrooms in your garden are really up to? Or how a slime mould could map the Tokyo subway system? Join us as we uncover the hidden secrets of fungi, from the incredible mycelium networks…

1
Morality 1:09:19

13d ago1:09:19

1:09:19

Morality! What is it? Where does it come from? And do we all have the same morals? Find out this week as the boys explore this deeply personal and subjective topic. Mitch defines morality for us and the key aspects that underpin it in the scientific community. Tom then explores four key areas of philosophical thought on morality: Kantian, Utilitari…

1
Will It Sequence? What grows on your food? 24:41

13d ago24:41

24:41

In this episode of Naked Genetics: What the latest genetics research has to say about restless leg syndrome; I put Illumina to the test and ask, 'what really grows on our food?'; And, what makes a tardigrade so tough? Like this podcast? Please help us by supporting the Naked ScientistsBy Will Tingle

1
EP 138: Personalised medicine using microbiome models with Dr. Almut Heinken 40:22

15d ago40:22

40:22

0:00 Introduction 1:45 Almut’s research experience, including two recent publications on genome-scale metabolic reconstruction human microorganisms Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple…

1
The Most Essential Tips for Biotechs Seeking Investment 23:17

19d ago23:17

23:17

Welcome to a special edition of Conversations in Drug Development, brought to you by the team at Boyds. In this episode, our host Harriet Edwards hands over the mic to two of her colleagues to discuss a critical topic for early-stage biotech companies: funding challenges and how to overcome them. Dr Nick Myers and Dr Neil Fish, share their extensiv…

1
Conservation 1:05:58

22d ago1:05:58

1:05:58

This week the boys are talking about Conservation! Mitch defines it for us and gives us knowledge on bees! Should we still care about them or are they doing well? Tom takes us on a tour of the IUCN and it’s red list of threatened species. How do we help species on the brink of extinction and what about those species that might go extinct before we …

1
EP 137: Mavis Machirori on promoting equity, diversity, and social justice in genomics research 41:40

21d ago41:40

41:40

0:00 Intro 1:30 Mavis’ career arc, from starting as a midwife to researching medical innovation and technology with an emphasis on advocacy and equity 7:00 Systemic issues that are easily overlooked in medical research and advancements Webinar: Participant Diversity: Increasing the Impact of Biomedical Research Webinar 10:00 Addressing Eurocentrici…

1
Episode 100: A Review 1:02:46

29d ago1:02:46

1:02:46

Welcome one and all to episode 100! We made it! On this weeks extra special episode the boys take time out to thank all of you amazing listeners who make this worthwhile. Mitch and Tom take a look back at some of their favourite moments, episodes, and topics. They provide some interesting updates to some old stories and tangent where their hearts d…

1
Episode 07 (Season 3) - Ice Cream & Cheese - Why VikingJersey Excels in USA 40:30

28d ago40:30

40:30

Jersey cow populations across the world are booming. Their cost-effectiveness, feed efficiency, good fertility, and high solids production make them highly desirable. In effect, it’s a cow built for the dairy industry of tomorrow. But what makes Jersey milk so desirable for cheese and ice cream production? And what do Nordic genetics have to offer …

1
EP 136: Developments in ring chromosome 20 research and advocacy with Allison Watson 40:57

28d ago40:57

40:57

0:00 Introduction 2:00 Allison’s personal journey to researching epilepsy and ring chromosome 20 syndrome 4:00 Biggest challenges families face with ring chromosome 20 syndrome 11:00 Incidence and prevalence of r(20) syndrome, and how we can improve data reliability 21:00 Applying next generation sequencing to r(20) syndrome gene research 29:00 Eng…

1
The Use of ATMPs in Oncology Clinical Trials 19:54

1M ago19:54

19:54

How can phase I studies with ATMPs address unmet needs in oncology and what are the challenges? In this episode of Conversations in Drug Development, Dr Katherine Bowen is joined by Pharmaceutical Physician, Dr Harriet Gray Stephens, to delve into the complexities of phase I oncology studies involving advanced therapy medicinal products (ATMPs). Jo…

1
The Science of Stories: Why do we tell them? 1:01:44

1M ago1:01:44

1:01:44

Storytelling! Why do we read books? Why do we tell each other stories of the past? Why is this, uniquely human behaviour, ubiquitous across the human race and prevalent in every single culture? Well, sit back and relax this week as we aim to explore just that! Tom explores the evolution of storytelling, was this a relatively new human tradition or …

1
EP 135: Integration of newborn sequencing programs into healthcare systems with Dr. Ingrid Holm 41:16

1M ago41:16

41:16

0:00 Introduction 1:30 Ingrid’s initial interests in genetics, paediatrics, and newborn screening 2:45 How the original BabySeq project, a pioneering newborn sequencing program got started, how it’s going, and the launch of BabySeq2 8:45 Lessons from BabySeq1 and goals for BabySeq2 10:30 Potential societal and long-term considerations for those inv…

1
Genetic Enieering: Should We Edit Our Genome? 1:05:45

1M ago1:05:45

1:05:45

GENETIC ENGINEERING! This week on the show Mitch and Tom explore how our DNA makes us who we are and the incredible ways in which scientists are able to hack into that system and edit our genes. To start the show Tom explores what genes are in the first place and how they are expressed before Mitch moves onto exploring the various methods of geneti…

1
EP 134: Prenatal genetic testing and the future of AI in genetic counselling with Kira Dineen, host of DNA Today 40:44

1M ago40:44

40:44

0:00 Introduction 1:00 The backstory of how Kira first started DNA Today in 2012, when she was still in high school! 3:30 Some of Kira’s favourite topics she has discussed on DNA Today, including the legacy of Henrietta Lacks, and the story of a Glee actress with down syndrome 10:00 Kira’s best practices for podcasting, from over 10 years of experi…

1
Dinosaurs and Fossils 1:05:43

2M ago1:05:43

1:05:43

DINOSAURS AND FOSSILS! This week on the show Mitch and Tom travel back to when reptiles held dominion over Earth. Tom explores the Mesozoic era and how flight developed in pterosaurs while Mitch explores how these beasts became things we find in the ground. The boys both explore their favourite dinosaurs and of course tangent along the way. Music: …

1
Will It Sequence? Hunting drug resistant bugs 22:37

2M ago22:37

22:37

In this month's edition of Naked Genetics: Why a genetic bottleneck created decades ago means some whales are in deep water; how wastewater is helping genetic sequencer track down deadly diseases; And, surf's up! how one beach dwelling creature is shredding the gnar in order to find food... Like this podcast? Please help us by supporting the Naked …

1
EP 133: Insights into pharmacogenomics and increasing diversity in genomics research with Dr. Emma Magavern 39:17

2M ago39:17

39:17

0:00 Introduction 2:00 The value of an English Literature degree in designing and analysing research studies in medicine 3:45 Emma’s entrance to pharmacogenomics and her transition from practising physician to genetics research 6:00 How the East London Genes and Health program is increasing representation of diverse populations, namely South Asians…

1
Ancient Civilisations: Japan II 54:53

2M ago54:53

54:53

Mitch and Tom return to where honour and tradition rules above all else, of course… it is Japan! What scientific innovations and technologies did the Japanese culture produce and how did they do it? Mitch looks at their time keeping system and production of intricate water clocks while Tom investigates the making of fabrics and the development of r…

1
EP 132: From mammoths to genome editing, trailblazing genetics with Dr. George Church 47:41

2M ago47:41

47:41

0:00 Introduction 1:00 George’s upcoming big projects, including developing full recycling, renewing energy, creating bioweather maps, and harnessing citizen science 6:45 Progress in engineering viral resistance in humans, including thoughts from pre- and post- pandemic 11:00 A swapped genetic code that prevents viral infections and gene transfer b…

1
How are GMO Regulations Impacting Clinical Development in Europe? 24:36

2M ago24:36

24:36

In this episode of Conversations in Drug Development, our host Harriet Edwards, is joined by Director of Regulatory Affairs, Dr Sabine Ruehle, to discuss the challenges of navigating genetically modified organism (GMO) regulations in clinical trials within Europe. This discussion helps decipher the nuanced environment of GMOs and their associated r…

1
Ancient Civilisations: Japan 1:01:39

2M ago1:01:39

1:01:39

This week your hosts take you back in time to where a sword on your hip decided your fate, where the art of calligraphy passed laws, and where tea ceremonies were the norm… Historic Japan! Tom explains why we do not refer to historic Japan as “ancient” before the boys launch into their research. Mitch reveals the impressive metallurgy skills develo…

1
EP 131: The potential of somatic genomics in drug discovery and development with Jake Rubens 44:57

2M ago44:57

44:57

0:00 Intro 0:40 Jake’s experiences as a serial entrepreneur starting five companies with a basis in genomic science 5:30 Opportunities for research and drug development in the realm of somatic science 9:20 Somatic evolution and how it provides valuable insights into disease mechanisms 12:30 Advantages and disadvantages of studying germline genome-w…

1
Where Biotech Meets the Business: Proteomics Product Management with Ivan Godinez from Proteintech 46:57

2M ago46:57

46:57

Ivan Godinez Director of Product Management at Proteintech (2:00) What does Ivan do for Proteintech? (4:10) Importance of single-cell level resolution and getting diverse data to answer scientific questions with different approaches (6:10) How did Ivan get to where he wanted? (8:12) Ivan's entrance into biotech, and subsequently, product management…

1
Ancient Civilisations: Ancient Egypt II 1:00:20

2M ago1:00:20

1:00:20

This week Mitch and Tom return to the land of the Nile and all that it touches: Ancient Egypt! This time your hosts actually discuss the making of the pyramids! How were the pyramids of Giza constructed? How were the rocks transported there? Was it Aliens or genius beyond its time? Tom speaks about solar eclipses in ancient times and the effect tha…

1
EP 130: Quarterly insights into noncoding variants and GWAS with Dr. Veera Rajagopal 51:56

2M ago51:56

51:56

Show Notes: 0:00 Introduction 1:20 How polydactyl mutations can inform research on non-coding variant mechanisms The importance of low-affinity binding between transcription factors and targets How these lessons can help us improve our understanding of drug and target discovery See Veera’s January round-up for more information: https://www.gwasstor…

1
Ancient Civilisations: Ancient Egypt 1:05:57

3M ago1:05:57

1:05:57

This week your hosts elope to where gods rules amongst humankind: Ancient Egypt! The boys carry on their historical They discuss the bounds of the ancient Egyptian empire and one of their most famous acts: mummification and the advances in medicine it led to! Tom explores what Egyptian life was like in the cities and rural areas and it’s not what y…

1
ADHD advantages, and mining microbiomes 22:40

3M ago22:40

22:40

This episode of Naked Genetics: has the evolutionary advantage to ADHD been uncovered? Also, We look at the microbiome of mining. And, the only vertebrate in the world that would thank you for saying that it looked like crap... Like this podcast? Please help us by supporting the Naked ScientistsBy Will Tingle

1
EP 129: Patient advocacy for genetic ALS and FTD with Jean Swidler, Executive Director of End the Legacy 38:44

3M ago38:44

38:44

0:00 Introduction 0:45 Jean’s personal experiences with family members with genetic ALS 10:00 Jean’s thoughts on the barriers and facilitators to providing treatment for those with genetic ALS 13:20 Insights into C9orf72, a common genetic determinant of ALS, and how it can also be associated with FTD 16:10 Jean’s experiences as an active advocate f…

1
Episode Update 0:49

3M ago0:49

0:49

Update on where your episode is and why you cant get it this week!By Tom Jenks and Mitchell Gatting

1
EP 128: Parkinson’s disease and precision medicine with Drs. James Beck and Ignacio Mata 50:18

3M ago50:18

50:18

0:00 Introduction 1:05 Insights into the PD GENEration’s (a programme from the Parkinson's Foundation) milestones and progress points for the upcoming year 3:30 The shifting attitudes and perspectives of neurologists and healthcare workers at the PD GENEration 5:50 Insights into Nacho’s work with the genetics of Parkinson’s disease 10:20 Barriers a…

1
Ancient Civilisations: Ancient Rome 1:10:14

3M ago1:10:14

1:10:14

Ancient Rome! The boys start a historical journey this week of ancient civilisations! What technological and scientific innovations did the Roman civilisation give to the world? When was “Ancient Rome” in the first place and how far did it expand? The boys explore the ingenious aqueduct system used to transport water hundreds of kilometres as well …

1
EP 127: Insights into precision medicine, fatty liver disease, and minimally invasive diagnostic tools with Dr. Mazen Noureddin 39:10

3M ago39:10

39:10

0:00 Intro 0:25 Mazen’s lifelong commitment to furthering the field of precision medicine in liver disease research, fueled by a personal connection of his grandmother developing MASH cirrhosis 2:30 Breakthroughs in the field of metabolic dysfunction-associated steatotic liver disease (MASLD) since the beginning of Mazen’s career 5:30 The potential…

1
Navigating Career Transitions in Biotech - Next Generation Sequencing (NGS) Edition with Joyee Yao from Complete Genomics 46:10

3M ago46:10

46:10

To learn more about BCLA’s events and consulting visit https://www.bc-la.org/ Complete Genomics: https://www.completegenomics.com/company/about-us/ Joyee Yao’s LinkedIn: https://www.linkedin.com/in/joyee-yao-74901212/ Follow our Instagram @insidebiotech for updates about episodes and upcoming guests! To learn more about BCLA’s events and consulting…

1
US Drug Development: The Latest Regulatory Trends and Initiatives 22:38

3M ago22:38

22:38

In this episode of Conversations in Drug Development, host Dr Harriet Edwards is joined by Katy Rudnick and Dr Julie Warner from Boyds to discuss US regulatory trends and initiatives at the FDA. This episode explores the FDA's recent organizational changes, pilot programs, and focus on innovative clinical trials, including the use of AI in drug dis…

1
Stress and Anxiety 1:12:41

3M ago1:12:41

1:12:41

Stress and Anxiety! Feelings and emotions that we all experience on varying scales… but how does it actually impact us? The boys explore the physiological impacts of stress on the body and how your body forms the stress response. Mitch explores the fight or flight response which now been expanded to include two new actions in the stress response: f…

1
EP 126: Patient-led research for ultra-rare disease drug development with Julia Taravella, Executive Director of Rare Trait Hope Fund 39:41

3M ago39:41

39:41

0:00 Introduction 0:25 Julia’s personal experience with ultra-rare diseases within her family 10:25 The importance of increasing accessibility to genetic testing across populations to learn more about ultra-rare diseases 14:00 The origin story of Rare Trait Hope Fund 23:50 Current research and next steps in developing potential gene therapies for a…

1
Episode 06 (Season 03) - Genomic vs. Daughter-proven Bulls - What Are Their Merits? 28:04

3M ago28:04

28:04

Daughter-proven bulls have been a staple in cattle breeding for generations; they have bred many world-class bloodlines. However, with technological development, more reliable tools have become available. Today, more and more farmers use genomic solutions to fully understand their herd’s potential. So, is this why farmers are transitioning away fro…

1
The Body Plan 1:06:52

4M ago1:06:52

1:06:52

Welcome back to The Information Entropy Podcast! The body plan: how does your body know where to grow an arm? A nose? Or your legs? Find out here! Tom explores the homeobox genes and how stem cells are vital for growing into new body parts and the different kind of body plans that are exhibited in the animal kingdom. Meanwhile, Mitch takes us on a …

1
EP 125: The future of UK Clinical Trial Policy: Innovation, integration, and game-changing legislation with Lord James O’Shaughnessy 45:23

4M ago45:23

45:23

0:00 Introduction 1:25 How Lord O’Shaughnessy became involved in scientific policy making and his path to writing the UK Commercial Clinical Trials Review. 04:05 How Lord O’Shaughnessy pivoted from education to a focus on life sciences 06:38 The biggest challenges Lord O’Shaughnessy faced during his time as Parliamentary Under Secretary for Health …

1
Computation and AI: Building AI platforms with a deep tech approach 31:38

4M ago31:38

31:38

Building a sector-specific AI platform, and in particular in a complex field like agriculture, is an involved journey. In this episode, we discuss the nuances of building such a platform at Cropin, a global pioneer in ag-intelligence and a company we’ve been proud to back. Join this discussion with Sujit Janardanan, chief marketing & customer offic…

1
Conspiracy Theories 1:04:24

4M ago1:04:24

1:04:24

Welcome back to The Information Entropy Podcast! Put your tin foil hats on because this week we are investigating conspiracy theories! What makes something a conspiracy theory in the first place? What are the different types of conspiracy theories? Why do people tend to believe in conspiracy theories? Find out all this and more on this week’s episo…

1
EP 124: How ReCode Therapeutics is pioneering tissue specific delivery of gene therapies for Primary Ciliary Dyskinesia with John Matthews 42:00

4M ago42:00

42:00

0:00 Introduction 01:10 How growing up in Malawi planted the seeds for John’s career in medicine and transition to therapeutic development 04:35 Why John focuses on rare diseases and conditions such as asthma 06:01 What has changed over the last decade in terms of treating and understanding asthma and the progress that genetics has enabled 07:31 Wh…

1
The Regulatory Challenges of Rare Disease Drug Development 29:37

4M ago29:37

29:37

To celebrate Rare Disease Day, we are back with another Conversation in Drug Development, this time discussing the unique challenges of rare disease drug development. Dr Eric Hardter, Associate Director of Regulatory Affairs at Boyds, joins our host Harriet Edwards to explore the need for early stakeholder involvement, the complexities of pediatric…

1
The roamin' Roman Empire, and Charles Darwin's love life 28:36

4M ago28:36

28:36

In this edition of Naked Genetics: The surprising findings of a roman empire diversity study; Are hybrid animals the way out of the biodiversity crisis? And, was charles darwin as romantic as he was scientifically brilliant? Like this podcast? Please help us by supporting the Naked ScientistsBy Will Tingle

1
Animals: Big vs Small 1:04:00

4M ago1:04:00

1:04:00

Welcome back to The Information Entropy Podcast! Why are some animals so big but others so small? Join us this week as we explore the possible mechanisms behind it all! Tom explores whether the size of an animals determines their niche or the other way around. Mitch looks at the role of thermoregulation with Bergmann’s law and why species that arri…

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