The Filtrate: Joel Topf Josh Waitzman With Special Guest: Brad Rovin (@BradRovin) Chief of nephrology at The Ohio State University Wexner Medical Center, one of the authors of the Nefigard trial. Koyal Jain (@koyaljainMD) Program director of the GN Fellowship at University of North Carolina Roger Rodby (@NephRodby) Associate program director of the…

The Filtrate: Joel Topf Swapnil Hiremath Josh Waitzman Nayan Arora Sophia Ambruso With Special Guest: Brendon Neuen Super smart guy and clinical trialist Vlado Perkovic Lead author of FLOW and friend of NephJC Editor Joel Topf Show Notes The manuscript (NEJM): Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes The acr…

The Filtrate: Joel Topf Swapnil Hiremath AC Gomez Nayan Arora With Special Guest: Anuja Java, complement god and pre-eclampsia research (Twitter) Shannon M. Clark, MD, FACOG, an honest to god, true, maternal-fetal medicine specialist. (Website | Instagram) Editor Nayan Arora Show Notes CHIP Study from 2015 (NEJM | NephMadness 2015) CHAP study from …

Outline Chapter 15 — Clinical Use of Diuretics - Among most commonly used drugs - Block NaCl reabsorption at different sites along the nephron - The ability to induce negative balance has made them useful in multiple diseases - Edematous states - Hypertension - Mechanism of action - Three major classes - Loop - NaK2Cl - Up to 25% of filtered sodium…

The Filtrate: Joel Topf Swapnil Hiremath Priya Yenebere Nayan Arora With Special Guest: Brendon Neuen Super smart guy and clinical trialist Michelle Rheault Lead author of DUPLEX and friend of the pod Show Notes Sparsentan versus Irbesartan in Focal Segmental Glomerulosclerosis NephJC Summary | PubMed | NEJM KDIGO FSGS Guidelines 2021 (PDF) Charact…

Outline Chapter 14 — Treatment - Treatment - Both oral and IV treatment can be used for volume replacement - The goal of therapy are to restore normovolemia - And to correct associated acid-base and electrolyte disorders - Oral Therapy - Usually can be accomplished with increased water and dietary sodium - May use salt tablets - Glucose often added…

The Filtrate: Joel Topf Swapnil Hiremath Jordy Cohen AC Gomez With Special Guest: Tim Anderson @TimAndersonMD Editor: Priya Yenebere Show Notes Clinical Outcomes of Intensive Inpatient Blood Pressure Management in Hospitalized Older Adults NephJC Summary | PubMed | JAMA Internal Medicine The Jordy AC collab: An Interactive Ambulatory Nephrology Cur…

Animal House Region NephMadness description by Tiffany Truong Editorial by Kelly Hyndman @DrKeeksPhD They May Look Cute, But Are All Animals Sweet? The Filtrate: Joel Topf Swapnil Hiremath Sophia Ambruso Josh Waitzman With Special Guest: Kelly Hyndman Editor: Sophia Ambruso Show Notes Animal House 2018 with Mark Zeidel, MD (AJKDblog) Animal House 2…

How Medicine Works, and When It Doesn’t Amazon The Filtrate: Joel Topf Josh Waitzman Jennie Lin With Special Guest: Jade Teakell Perry Wilson Editor: Joel Topf Show Notes Understanding Medical Research: Your Facebook Friend is Wrong. Coursera Illusory truth effect (Wikipedia) Number needed to treat (Wikipedia) NNT at MedPage Today: NNT on NephJC De…

The Filtrate: Joel Topf Nayan Aurora Sophia Ambruso With Special Guest: Michael Collins Editor: Nayan Aurora Show Notes: Twitter is now X (NYT) Michael Collins (the astronaut, not the real one) PlasmaLyte by Baxter NephJC BEST Fluids summary Early Goal Directed Therapy for Sepsis NEJM manuscript which changed practice patterns and welcomed in an er…

Outline Chapter 14 - Hypovolemic States - Etiology - True volume depletion occurs when fluid is lost from from the extracellular fluid at a rate exceeding intake - Can come the GI tract - Lungs - Urine - Sequestration in the body in a “third space” that is not in equilibrium with the extracellular fluid. - When losses occur two responses ameliorate…

The Filtrate: Joel Topf Swapnil Hiremath Sophia Ambruso AC Gomez Josh Waitzman Jennie Lin Nayan Arora The Curbsiders Matt F. Watto (@DoctorWatto) Paul Nelson Williams, America’s primary care physician (@PaulNWilliamz) With Special Guest: JD Foster (@KidneyVet) Sayed Tabatabai (@TheRealDoctorT) Nephrologist in Austin and the author of These Vital Si…

The Filtrate: Joel Topf Swapnil Hiremath Sophia Ambruso AC Gomez With Special Guest: Amit Garg (@AmitXGarg) Nephrologist at Western University, London, and lead PI of the EnAKT LKD trial. Susan Q. McKenzie (LinkedIn) Co-Founder & Chair, Transplant Ambassador Program. President of the Kidney Patient and Donor Alliance of Canada. Editor: Joel Topf Sh…

By NephJC

Bicarbonate did not slow the loss of GFR in this well done Swiss, single-blind study of transplant patients. The Filtrate: Joel Topf Nayan Arora Swapnil Hiremath Pirya Yenebere With Special Guest: Nav Tangri nephrologist and epidemiology at the University of Manitoba Editor: Nayan Arora Show Notes: Arsenal FC The London study that kicked it all off…

References JC mentioned that the diagnostic accuracy of 24 hour urine collection increases with more collections! Metabolic evaluation of patients with recurrent idiopathic calcium nephrolithiasis We didn't refer to a particular study on sodium intake and the 24 hour urine but this meta-analysis Comparison of 24‐hour urine and 24‐hour diet recall f…

The Filtrate: Joel Topf Nayan Arora Sophia Ambruso With Special Guest: Boback Ziaeian @boback Assistant Professor of Medicine David Geffen School of Medicine at UCLA. His Google Schoolar page is better than yours. And returning for her fourth time (why do we keep inviting her back?) Sadiya Khan @heartDocSadiya Assistant Professor of Medicine (Cardi…

Today we are joined by Dr. Brian Locke, recently graduated pulmonary-critical care fellow, who takes us on a journey of avoiding statistical fallacies. Does metformin reduce the likelihood of long COVID? Should we give platelet transfusions to thrombocytopenic patients before central line placement? Did the CANVAS trial change practice in cancer as…

The Filtrate: Joel Topf Swapnil Hiremath Josh Waitzman Nayan Arora Sophia Ambruso With Special Guest: Megan Prochaska Assistant professor of medicine at University of Chicago John Asplin Medical Director Consultant LithoLink (Twitter) Editor: Joel Topf Show Notes: The LithoLink website Stone Camp tweet Prevention of Repeated Episodes of Kidney Ston…

Today we have a special guest, Dr. Joel Topf, board-certified nephrologist and medical educator extraordinaire. Our listeners will likely recognize Dr. Topf from his prolific tweeting @Kidney_boy, as well as his numerous appearances on the Curbsiders podcast. He is a co-founder of the NephJC on Twitter, and host and founder of the NephJC podcast Fr…

References We considered the complexity of the machinery to excrete ammonium in the context of research on dietary protein and how high protein intake may increase glomerular pressure and contribute to progressive renal disease (many refer to this as the “Brenner hypothesis”). Dietary protein intake and the progressive nature of kidney disease: the…

The first assignment in the Podcast rotation is to record a short essay on why the NSMC Intern chose nephrology (or pediatrics, or nursing, or medical school, etc…). The intern then uses this recording to practice editing, adding music and finally publishing a podcast (if they want to). Here is Nyi Min Han’s audio essay. Subscribe…

The first assignment in the Podcast rotation is to record a short essay on why the NSMC Intern chose nephrology (or pediatrics, or nursing, or medical school, etc…). The intern then uses this recording to practice editing, adding music and finally publishing a podcast (if they want to). Here is Sadia Jahan’s audio essay. Subscribe…

The first assignment in the Podcast rotation is to record a short essay on why the NSMC Intern chose nephrology (or pediatrics, or nursing, or medical school, etc…). The intern then uses this recording to practice editing, adding music and finally publishing a podcast (if they want to). Here is Saumya Vishnoi’s audio essay. Subscribe…

The Filtrate: Joel Topf Swapnil Hiremath Josh Waitzman Jordy Cohen With Special Guest: Areef ishani lead author and Chief of Medicine VA Minneapolis Editor: Nayan Arora Show Notes: MRFIT switches diuretics and finds better outcomes. Swapnil shows how many studies he is familiar with by spewing out a string of them. Chlorthalidone wins: ALLHAT, MRFI…

This week we have special guest, Dr. Adam Spivak, to talk about the new study on doxycycline post-exposure prophylaxis for STIs. Dr. Spivak is an infectious disease expert and works in both an HIV clinic and a free PrEP clinic. I also review the latest COVID-19 anticoagulation trial and a paper looking at rates of fracture non-union in people who r…

The first assignment in the Podcast rotation is to record a short essay on why the NSMC Intern chose nephrology (or pediatrics, or nursing, or medical school, etc…). The intern then uses this recording to practice editing, adding music and finally publishing a podcast (if they want to). Here is Brammah R. Thangarajah’s audio essay. Subscribe…

The Channelers went where no nephrology podcasters have gone before, recording in front of a live audience at the National Kidney Foundation Clinical Meeting in Austin. We had all eight Channelers doing a live podcast. We did a Freely Filtered-inspired draft of the best diuretics. The draft order: Leticia Rolon Anna Gaddy Joel Topf Roger Rodby Josh…

The first assignment in the Podcast rotation is to record a short essay on why the NSMC Intern chose nephrology (or pediatrics, or nursing, or medical school, etc…). The intern then uses this recording to practice editing, adding music and finally publishing a podcast (if they want to). Here is Vishnu Reddy’s audio essay. Subscribe…

The first assignment in the Podcast rotation is to record a short essay on why the NSMC Intern chose nephrology (or pediatrics, or nursing, or medical school, etc…). The intern then uses this recording to practice editing, adding music and finally publishing a podcast (if they want to). Here is Sherry Wang’s audio essay. Subscribe…

Today we have special guest, Dr. Sarah Gilligan, a nephrologist, to talk about the new study of thiazides for kidney stones. We all learn in medical school that thiazides reduce urinary excretion of calcium, but does that really translate to fewer kidney stones? We also have Dr. Brian Locke on to talk about the CAPE COD trial, a big new critical ca…

The Filtrate: Joel Topf Swapnil Hiremath Josh Waitzman Sophia Ambruso With Special Guest: Anna Vinakova Associate Professor of Medicine at Virginia Commonwealth University. NephMadness Executive. Vanuja Java is a transplant nephrologist at Washington University in St. Louis, MO. Her research involves functional characterization of genetic variants …

By Channel Your Enthusiasm

Welcome to the NephMadness PodCrawl The idea behind a podcrawl is for a variety of podcasts to coordinate on timing and topic to push a theme and get each other’s listeners to explore all of the podcasts. One of the first goals behind NephMadness was to build a community and in the early years of Twitter, NephMadness was central to the formation of…