Yes, these are popular science stories from the history of medicine. And no, this is not another retelling of biographies or 10,000ft. thematic reviews. Here we discuss specific events and talk about the unusual, intriguing, and often unbelievable life circumstances that accompanied this or that medical achievement. Craving more? Go to our Facebook page to view literary sources and texts. Laboraverum is brought to you by Meteor Production and narrated by its author Ed Kanalosh, MD, Ph.D., an ...
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Year of 1882 – How roses on a tangerine tree, dismissal from the university and marine larvae came together to make the discovery of immunity possible
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The year 1882 is marked by the discovery of immunity. It’s associated with many very non-trivial events that are not usually associated in our minds with the Nobel Prize. But in fact, this story is even more amazing.By Eduard Kanalosh
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Laboraverum News, 2024-06-18: strange bacteria create a completely new gene when infected with a virus
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Surprising facts have been discovered about Klebsiella pneumoniae: its cytoplasm contains a seemingly useless reverse transcriptase enzyme and equally useless tiny pieces of RNA, and these useless structures suddenly begin to interact in the event of a viral attack on the bacterium. As a result of their interaction, the bacterium synthesizes a gene…
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Laboraverum News, 2024-06-12: New findings about why autism is so much more common in men than women
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We don't know why mental disorders such as schizophrenia, bipolar disorder or autism spectrum disorder are so much more common in men than in women, but new research suggests this may be due to significantly greater variability in the way RNA is synthesised on genes in women's brains. The researchers analysed 2,160 brain samples from patients with …
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Laboraverum News, 2024-06-05: First male contraceptive candidate offers hope of giving men better control over conception
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Contraceptive options for men are limited to condoms and coitus interruptus, which reduce pleasure, and vasectomy, which permanently sterilises the man. A non-hormonal inhibitor of a serine/threonine-protein kinase 33 (STK33) has just been shown to cause reversible male infertility without noticeable toxicity. At this stage it has only been tested …
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Year 1686: how the knife that cut the king's anus made surgeons doctors
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In the autumn of 1686, Paris was full of rumours. It was said that at dawn, corpses were discovered in cemeteries, again and again. Not one or two, but already seventy five! With their anuses pierced with a knife! There were also other rumours - that le Roi Soleil, our Sun King, was seriously ill, that an endless stream of doctors and healers tried…
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Laboraverum News, 2024-05-03: When was the last time in evolution that a new cellular organelle was formed? Incredibly, this is happening right now!
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The cyanobacterium UCYN-A lives inside single-celled algae as an endosymbiont. The researchers discovered that the cyanobacterium now imports from the host cell not only nutrients, which is typical for symbionts, but also unchanged proteins to build its own body, including proteins essential for biosynthesis, growth, and division. An isolated cyano…
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Laboraverum News, 2024-05-01: we have cells that, even after their own death, continue to kill invaders. How?
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The life of neutrophils, the most common white blood cells, is measured in hours. They fight against attackers that invade our body and then die, but they continue to fight after death. In the process of their death, neutrophils can cause their DNA to unwind. The pores of their nuclei open and strands of DNA leave the nuclei. These threads shoot ou…
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Laboraverum News, 2024-04-24: we've all heard of computer hacking, but what about to hack the mosquito?
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In the city of Yogyakarta, Indonesia, the number of dengue fever cases has decreased by 77%. Even more impressive results were achieved in northern Queensland, Australia. The reduction in dengue cases here was 96%. While the results themselves are impressive, what is stunning is not what was achieved, but how it was achieved!…
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Laboraverum News, 2024-04-03: Are our advanced nerves a deformation caused by an ancient infection?
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Researchers have demonstrated that myelin, a key element of our nerve fibres, can be a deformation caused by a virus that infected some jawed fish 360 million years ago, and thus who we are, including to some extent our intelligence, originates from that infection.By Eduard Kanalosh
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Laboraverum, year 1774: Establishing your medical practice, tobacco smoke enema and good deeds
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In April 1774, William Hawes, a 38-year-old medical practitioner, sat with 33 other gentlemen in Chapter Coffee House in St. Paul's Churchyard in London. The group was concerned about the number of people mistaken for dead who could still be resuscitated. What Hawes and this group decided to do suddenly brought them recognition not only from the pe…
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Year 1683: how shogun, the energy of Qi and the Iceman Ötzi brought acupuncture to Europe
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The Age of Exploration gave birth to truly great hopes in Europe. Each ship returning from distant worlds brought something new, unheard of, unseen. In medicine, hopes were about new medicines, new methods, new knowledge. In 1683, the Dutch physician Willem ten Rhijne published a book about what he had learned in Japan, a country unknown to most Eu…
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Year 1966: How did a meteorite, clean room and five deaths 40 years ago make lead illegal?
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In 1966, the first witness at the hearings on lead pollution was a university professor hired by a fuel additive company. The main opponent at that time was in Antarctica, conducting his research. However, he suddenly entered the room and immediately jumped into the discussion. Many wondered why this man named Patterson was so passionate about figh…
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Year 1545, ten interesting facts to the main story
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If you liked our story about Ambroise Pare, four frostbitten noses that no one wanted to cut off, boiling oil, poisonous gunpowder and deep secrets that should never be revealed, then these 10 facts will definitely be of interest to you.By Eduard Kanalosh
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Year 1545: how four frostbitten noses helped medical science move away from the writings of antiquity
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It was in this year that the development of modern medical science began. No exaggeration. 1545 was the first year. In the medical world of that time, where everything began and ended with the works of ancient authors, barber-surgeon Ambrois Paré proposed three innovative ideas: testing everything through experience, learning through comparison, an…
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Laboraverum News, 2024-03-13: are epigenetic treatments coming? And specifically, for high blood cholesterol?
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The researchers used proteins called “zinc-finger proteins”. These proteins can attach to the DNA strand in very specific points. In the experiment, these proteins were designed to bind to the PCSK9 gene, which is known to increase blood cholesterol levels. The cholesterol levels in experimental mice dropped within a month of the procedure and rema…
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Year 300 B.C.: Was the first autopsy performed on a living person?
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Today we’ll talk about autopsies - an indispensable tool for studying the body. Autopsies for scientific purposes, as the title of this story suggests, began to be performed sometime around 300 BC. However, it is said that the first autopsies were performed on living people. Is that really true? Could this be true? Dissect a living person?…
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2900 B.C.: who killed 78 people at once and why this mass death is important for human history?
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Today we are investigating the mysterious death of 78 people. This happened about 5000 years ago, in 2900 BC. In the summer of 2018, archaeologists discovered a mass grave in a prehistoric passage tomb near Falbügden in western Sweden. All those buried died at the same time. There were no visible damages to the bones, not a single scratch. Toxicolo…
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Laboraverum News, 2024-02-28: How the X chromosome might provoke autoimmune diseases
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Researchers bioengineered male mice to produce a special nucleoprotein “sleeve” that envelopes one of two X chromosomes in women but is absent in men. These experimental animals developed autoimmune reactions, including the appearance of autoimmune antibodies, greater ease of attack by immune cells, and associated tissue damage. If confirmed, it wo…
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Year 2900 B.C. , interesting facts: the death of Trypillia and the spread of multiple sclerosis
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The disappearance of Trypillia might pave the way for the spread of multiple sclerosis throughout the world. Researchers collected and sequenced the DNA of ancient Europeans from 317 excavated skeletons ranging in age from 3,000 to 11,000 years. The scientists combined their findings with genomic data from 1,300 other ancient Eurasians and compared…
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Laboraverum, year 1977: An escaped disease that caused the Red Flu pandemic but didn't make much of a splash
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How would you feel if you met a dinosaur in your local city park? Not a vision or an imitation, but a real living dinosaur? This is exactly the feeling that scientists experienced when examining influenza patients in 1977. What had died out many years ago suddenly appeared before them, alive, active, and dangerous… And a year later, a British profe…
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Laboraverum News, 2024-01-17: Additional 49% reduction in deaths from III/IV stage of melanoma
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In a phase 2b clinical trial, adding tumour’s messenger RNA to immunotherapy reduced deaths in stage III/IV melanoma by an additional 49%. These are the advanced stages of the cancer when metastases spread to several lymph nodes near the primary tumour and start to spread to distant areas of the body such as the brain, lungs, liver, etc. Patients w…
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Laboraverum News, 2024-02-14: could Alzheimer's disease actually be five different diseases?
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Alzheimer's disease is thought to have 5 different organic substrates, produce 5 different laboratory values, have 5 different prognoses, and require 5 different treatments. If the differences are so significant and multifaceted, then aren't these actually 5 different diseases?By Eduard Kanalosh
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Year 802 – 7 interesting facts related to story of why medicine stopped for 600 years and how it was born again
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Last time we talked about a sad period of 6 centuries, starting from the death of Galen in 216 and ending in 802, when the first university was founded. During these 6 centuries, ancient medicine was almost completely lost, but the appearance of the Salerno school was its new birth. Today we are going to talk about 7 random but interesting facts re…
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Year 1122: a mysterious medieval treatise from the library of Lorenzo de' Medici, or Did women engage in medical research a thousand years ago?
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The Middle Ages were a time of dark superstitions, famine, endless wars, devastating epidemics, witch hunts and the absolute power of men over women. At the same time, we know about women who ruled countries, led armies and changed the course of history. In other words, there were exceptions to the general rule. However, if there was one area of me…
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Laboraverum News, 2024-01-31: vibrating obesity pill – will it ever reach consumers?
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The experimental animals ate 40% less after swallowing the vibrating capsule. The effect did not involve any chemicals substances or biochemical reactions at all, only a 38-minute mechanical impact. To achieve this effect at the next meal, the animal needed to take another vibrating capsule. Sounds like a possible solution to the obesity problem, b…
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Laboraverum News, 2023-12: The artificially created living lumps of our own cells guide other cells
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You look through a microscope and see tiny balls created by your own cells. These balls are rowed by thousands of tiny oars called cilia. The balls move freely and control the healing of the damaged layer of neurons. The researchers call these balls “human robots” or “anthrobots.”By Eduard Kanalosh
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Year 802: Why was ancient medicine lost and how did the revival of medicine begin?
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Today we are talking about the year 802, or more precisely about the mysterious period that preceded it and made that year so special for us. This is 6 centuries, starting from 216 and ending in 802. What is about these 6 centuries? During this time, ancient medicine was almost completely lost. All that was happening then day by day was the loss of…
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Laboraverum News, year 2023: final year's ranking of truly impressive biomedical discoveries
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Only the future will tell which of the biomedical discoveries of 2023 are real breakthroughs. However, even before the future delivers its verdict, it's only natural for us to perceive some of them as particularly exciting. Here are the top 7 for 2023.By Eduard Kanalosh
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Year 2100 B.C.: Time When the medical profession was born
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Obviously, the answer is in the title, the medical profession existed as far back as 2100 BC, but if you want to know the details, we'll discuss them. It is obvious that from the very beginning people have tried to heal themselves and their loved ones, but when did healing become a separate, distinctive profession? And how did it manage to survive …
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