))
AAV Vectors For In Vitro and In Vivo Uses
Manage episode 345187823 series 3408836
Content provided by Genscriptprobio. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Genscriptprobio or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
When combined with modern technology for gene expression including cells-specific promoters as well as the Cre/lox system and genome-editing, AAVs provide a feasible quick, cost-effective, and affordable alternative to conditional knockouts or the transgenic mice models. But, there are many obstacles to widespread AAV cell line use, including ineffective methods for purification and small viral numbers. We present an improved procedure to make AAVs with serotypes that are not dependent on their genotypes.
9 episodes
Share
