Targeting Cellular Senescence for Healthier, More Youthful Skin With Dr. Alessandra Zonari

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

I'm thrilled to be joined by Dr. Alessandra Zonari to take a deep dive into a breakthrough in skincare science that has caught my attention—OneSkin's OS-01 peptide. This episode explores how OS-01 targets cellular senescence, the core of aging, potentially transforming skin health - preserving function, not just aesthetics. I'm particularly impressed by OneSkin's commitment to rigorous research and evidence-based results. Their approach rejuvenates skin function in addition to enhancing its natural radiance, elasticity, and even its microbiome. This could be a significant advancement for individuals managing aging skin or conditions like atopic dermatitis.

Throughout our discussion, we explore the scientific foundation behind OS-01 and its clinical implications and uncover how this peptide may redefine skincare protocols, offering new possibilities for healthier, more radiant skin. Whether you're a practitioner seeking innovative solutions for patients for ultrasensitive skin or dermatitis, or someone passionate about maintaining skin health, this episode promises insights that could reshape your approach to skincare. And if you’re using OneSkin, I'd be curious to hear from you. You can post a comment wherever you're listening to this or email me directly at DrKaraFitzgerald.com. ~DrKF

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

GUEST DETAILS

Alessandra Zonari, PhD

OneSkin co-founder and Chief Scientific Officer, Alessandra Zonari, PhD joined the early team in 2017 dedicating her time to understanding the underlying mechanism of the aging process and developing solutions to reverse skin’s biological age. Zonari is the co-inventor of five patents and has published more than 20 peer-reviewed papers in scientific journals.

Email: [e-mail]

THANKS TO OUR SPONSOR

OneSkin: Website

PROMO

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SHOW NOTES

Animated science video explaining how OS-01 works Another Study Website
Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models Study Website
In vitro and in vivo toxicity assessment of the senotherapeutic Peptide 14 Study Website
Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging Another Study Website
MolClock: Estimate DNA methylation age of Skin Tissues Study Website
Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation Another Study Website
Senotherapeutics, Senolytics, and Senomorphics -- What are they and what is OS-01? Study Website