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#20 B cell receptor substitution profile prediction and SPURF with Kristian Davidsen and Amrit Dhar
Manage episode 204718939 series 1537951
Content provided by Roman Cheplyaka. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Roman Cheplyaka or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
In this episode Kristian Davidsen and Amrit Dhar present their project called SPURF. SPURF can predict the B cell receptor (BCR) substitution profile of a given clonal family based on a single representative sequence from that family. SPURF works by fitting a tensor regression model to publicly available Rep-seq data.
Links:
- Preprint: Predicting B Cell Receptor Substitution Profiles Using Public Repertoire Data
- Blog post about SPURF by Erick Matsen
- SPURF on GitHub
If you enjoyed this episode, please consider supporting the podcast on Patreon.
70 episodes
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Manage episode 204718939 series 1537951
Content provided by Roman Cheplyaka. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Roman Cheplyaka or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
In this episode Kristian Davidsen and Amrit Dhar present their project called SPURF. SPURF can predict the B cell receptor (BCR) substitution profile of a given clonal family based on a single representative sequence from that family. SPURF works by fitting a tensor regression model to publicly available Rep-seq data.
Links:
- Preprint: Predicting B Cell Receptor Substitution Profiles Using Public Repertoire Data
- Blog post about SPURF by Erick Matsen
- SPURF on GitHub
If you enjoyed this episode, please consider supporting the podcast on Patreon.
70 episodes
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Similar to the bioinformatics chat
How can we, humans, look at our relationship to nature differently? In season three of Going Wild, on top of stories about animals, we invite you to journey through the entire ecological web — from the tiniest of life forms to apex predators — alongside the scientists, activists and adventurers who study it. Wildlife biologist and host Dr. Rae Wynn-Grant has been studying wild animals in their natural habitats all over the world for years. Our award-winning podcast takes you inside the hidde ...
…
continue reading
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…
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…
continue reading
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…
continue reading
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…
continue reading
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…
continue reading
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