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Polly Matzinger, PhD: Dangerous Ideas in Immunology

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Manage episode 351448115 series 2918293
Content provided by The External Medicine Podcast. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by The External Medicine Podcast or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
In this conversation, Daniel Belkin and Mitch Belkin interview Polly Matzinger, PhD, about her model of immunology, which she calls 'The Danger Model'. They discuss how The Danger Model helps explain aspects of immunology ignored by the self/non-self model, including why mothers don't reject their fetuses, autoimmune diseases, organ transplant rejection, cancer surveillance, allergy and more.
Who is Polly Matzinger?

Polly Matzinger received her PhD in Biology from UCSD before completing a postdoc at Cambridge. She then worked at the Basel Institute for Immunology before moving to the NIH, where she was a section head at the National Institute of Allergy and Infectious Diseases of the so-called “Ghost Lab”. She is the creator of the Danger Model (1994), which argues the immune system discriminates between dangerous and safe by recognition of pathogens or alarm signals from injured or stressed cells and tissues.

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Follow us at @ExMedPod
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43 episodes

Artwork
iconShare
 
Manage episode 351448115 series 2918293
Content provided by The External Medicine Podcast. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by The External Medicine Podcast or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
In this conversation, Daniel Belkin and Mitch Belkin interview Polly Matzinger, PhD, about her model of immunology, which she calls 'The Danger Model'. They discuss how The Danger Model helps explain aspects of immunology ignored by the self/non-self model, including why mothers don't reject their fetuses, autoimmune diseases, organ transplant rejection, cancer surveillance, allergy and more.
Who is Polly Matzinger?

Polly Matzinger received her PhD in Biology from UCSD before completing a postdoc at Cambridge. She then worked at the Basel Institute for Immunology before moving to the NIH, where she was a section head at the National Institute of Allergy and Infectious Diseases of the so-called “Ghost Lab”. She is the creator of the Danger Model (1994), which argues the immune system discriminates between dangerous and safe by recognition of pathogens or alarm signals from injured or stressed cells and tissues.

Support the Show.

Follow us at @ExMedPod
Subscribe to our Youtube channel
Consider supporting us on Patreon

  continue reading

43 episodes

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