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The Hep-cast

World Hepatitis Alliance and Gilead Sciences Europe Limited

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Join us as we go beyond the statistics to explore the human impact of one of the greatest health crises of our time. Over 350 million people are living with viral hepatitis worldwide. The Hep-cast is about the people whose lives have been changed by viral hepatitis and those fighting to eliminate it as a public health threat by 2030. Guests include people living with viral hepatitis, healthcare professionals, policymakers, and activists. They will expose the human cost of this cruel virus an ...
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Conversations with CEI

Clinical Education Initiative

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Conversations with Clinical Education Initiative (CEI) features clinical experts in HIV Primary Care and Prevention, Sexual Health, Hepatitis C and Drug User Health. Our episodes feature CEI clinicians’ experience and insight on the current health issues, alongside the latest news and guidelines on our areas of expertise. This podcast is produced by the CEI, a New York State Department of Health AIDS Institute program.
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Vision To Prevent and Cure Liver Disease Mission To advance and disseminate the science and practice of hepatology, and to promote liver health and quality patient care AASLD is the leading organization of scientists and healthcare professionals committed to preventing and curing liver disease. AASLD was founded in 1950 by a small group of leading liver specialists (including Hans Popper, Leon Schiff, Fred Hoffbauer, Cecil Watson, Jesse Bollman, and Sheila Sherlock, to name a few) to bring t ...
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The latest health news, including microRNA researchers winning this year's Nobel Prize in Physiology or Medicine. What's the big deal with these tiny molecules? And Marburg virus has been detected in hospitals across Rwanda for the first time. The virus causes a haemorrhagic fever similar to Ebola. References Medicine Nobel awarded for gene-regulat…
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Wait times for ADHD treatment, or mental health support, can be long. So is there a pocket-sized solution? c Their efficacy is the subject of a new review, aiming to figure out just how helpful these interventions can be. Guest Joseph McGuire, Associate Professor of Psychiatry and Behavioural Sciences at Johns Hopkins School of Medicine References …
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In epilepsy, seizures are caused by an 'electrical storm' in the brain that can be seen during an EEG test. But there is another kind of seizure, which presents the same but cannot be seen on an EEG. Despite being so common, there are few treatments for functional seizures and functional neurological disorder (FND). Guest Jackie, participant in Re-…
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The rate of skin infections in Aboriginal children living in remote communities has halved over the course of a major five-year study. Untreated skin infections can cause rheumatic heart disease, sepsis and kidney disease – all of which disproportionately affect Aboriginal and Torres Strait Islander Australians. A trial has found regular skin check…
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Are current guidelines failing chronic pain patients with a history of substance-use disorders? Find out why Dr. Wang and Dr. Kelly are calling for urgent policy changes and how updated guidelines can support effective pain management. Join us for a compelling discussion on the intersection of chronic pain and substance use disorders with insights …
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The latest health news, including a US study linking indoor radon exposure to childhood leukaemia risk. Why Australian adults do (and don't) get vaccinated against the flu. And new rules come into effect banning the compounding of popular weight loss products. References Domestic radon exposure and childhood cancer risk by site and sex in 727 count…
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Both attention deficit-hyperactivity disorder (ADHD) and dyslexia share symptoms, so do they share genes? Researchers have looked at the genomes of thousands of people to pinpoint places where the conditions overlap. They found ADHD aligns more closely with dyslexia than autism, suggesting it might be better termed as a learning difficulty than a p…
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Millions of people are using period-tracking apps to record their menstrual cycle. In some cases, women are relying on these apps to prevent pregnancy, or to tell them when they’re most fertile when they are trying to have a baby. How accurate are they, and should you be trusting these companies with your health data? Guest Dr Emmalee Ford, biochem…
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We can use technology to fill the gap when the brain no longer sends the right signals to the body. Brain-computer interfaces have helped people who've lost movement to move again. But so far, none of these products have been approved for use outside of research settings. Guest Michelle Patrick Krueger, IUCRC BRAIN Center at the University of Houst…
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For years, so-called 'Blue Zones' have been promoted as having a higher than average number of long-lived people. It was thought their lifestyles were behind their longevity. But upon further investigation, the whole notion of 'Blue Zones' has fallen apart. The researcher responsible has won the first Ig Nobel prize for demography. References UCL d…
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Unhealthy weight gain in the early years of childhood can have lifelong implications. While prevention is the main objective, sometimes it is necessary to intervene with weight loss strategies. So how is this done safely – keeping in mind the very real risk of triggering eating disorders in young people? Guest Dr Natalie Lister, research dietitian …
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Getting screened for cancer is a stressful experience, especially when the methods can be invasive. New research indicates fewer men would have to undergo biopsies for prostate cancer, when an MRI is undertaken first. Guest Associate Professor Jeremy Grummet, urological surgeon References Results after Four Years of Screening for Prostate Cancer wi…
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Hodgkin lymphoma is a cancer that typically affects young adults. Because of this, there are many things to consider before treatment starts – not just how effective it will be, but its long-term impacts. Australian researchers have been part of a clinical trial to find effective first-line treatments for the disease that prevent toxic side effects…
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Superbugs expected to kill 50 million people by 2050. Trial tests COVID antiviral Paxlovid's usefulness. Alcohol is linked to higher cancer rates in young people. And a tobacco giant releases inhaler company after backlash. References Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050 Nirmatr…
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The government is preparing legislation to ban life insurers from using genetic testing results to discriminate coverage. The practice put Australians off getting tested, meaning they potentially missed out on important health information. Could this reform lead to population-sized screening for high risk genes? Guest Jane Tiller, the ethical legal…
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Children with raised levels of inflammation were associated with an increased risk of developing psychosis disorder, severe depression, and high levels of insulin resistance in their 20s. Guest Dr Edward Palmer, a trainee psychiatrist and academic clinical fellow at the University of Birmingham References Trajectories of Inflammation in Youth and R…
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Adelaide-based company Micro-X is transforming radiology with smaller and less resource intensive X-ray technology. The tech could see CT scanners small enough to fit in ambulances providing vital stroke diagnosis on the spot. Guest Anthony Skeats is the Chief Operating Officer at Micro-X References Ready to scan: designing the Micro-X Head CT for …
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The federal government has announced a rethink on suicide prevention this week, a more holistic approach that doesn’t just look to mental health and clinical response but to social determinants that lead to high risk of suicide. The Lancet released a series, also this week, which similarly pushes for a public health approach to suicide prevention. …
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People don't generally notice a kidney stone until it gets big and causes severe pain. So it's hard to trace back to when it actually started forming. Well, one scientist decided to age his own kidney stone using carbon dating techniques usually used for dating ancient rock art. Guest Dr Vladimir Levchenko, research scientist at Australian Nuclear …
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As Ebola continues to be a global threat, a major review into the real-world effectiveness of the Ebola vaccine offers some reassuring results. Guest Dr Sophie Meakin is an epidemiologist with Epicentre, the epidemiology and medical research arm of Médecins Sans Frontières References Effectiveness of rVSV-ZEBOV vaccination during the 2018–20 Ebola …
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“This podcast discusses the recent presentation of data for lenacapavir, a potent capsid inhibitor for HIV that was 100% effective in preventing HIV infection in cis-gender woman at risk for HIV. If approved, it will offer an exciting new option to prevent HIV which should dramatically improve our chances of reaching the goal of totally eliminating…
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A story for the many parents who allow their children some screen time, and are concerned about the potential negative effects of it. A recent study has found a link between tablet use by preschoolers and angry outbursts. This behavioural effect could be due to a dependency on the device for emotional regulation, but the results are stark. Guest Dr…
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We've heard a lot in recent years about how damaging concussion in professional sport can be to long-term brain health. But we don't know a lot about the impacts of mild concussions. Well there's now an app for that. And one recent study found having a sports-related concussion didn't seem to have a detrimental effect on cognition and was linked to…
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Men might need a little bit more convincing when it comes to going to the doctors but if there are issues below the belt it might be worth getting yourself checked. New research suggests erectile dysfunction or peeing in the night might be indicators of a bigger problem. Guest Dr Sam Tafari, andrology and men’s health fellow at the Royal Adelaide h…
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An update on COVID-19 figures, plus the latest research on vaccines and long-COVID. What are the long-term outcomes of people who experienced myocarditis after COVID infection or vaccination? And why were there differences in mental health outcomes for the unvaccinated and the vaccinated? References Long-Term Prognosis of Patients With Myocarditis …
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More attention is being paid to toxins and their effects on the human body – like PFAS chemicals, microplastics and heavy metals. A guide has been released providing advice to parents, childcare centres and policymakers. It provides practical approaches to reduce the risks from known toxins. Guest Dr Rachael Wakefield-Rann, Institute for Sustainabl…
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Many people use food tracking apps, whether for weight loss purposes, or to help manage a medical condition. But when it comes to how much energy, fat, protein or sodium is in a certain food, how accurate are they? Researchers have looked at hundreds of apps and identified some of their blind spots — including multicultural meals. Guest Dr Juliana …
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Insomnia is so common, it’s likely everyone will experience bouts of it at some point in their life. While not everyone will need treatment, for those who do, it can be difficult to access. A digital version of cognitive behavioural therapy for insomnia (CBTi) could open up treatment to more people. Guest Professor Robert Adams, specialist respirat…
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New evidence is supporting the mass distribution of azithromycin to children in sub-Saharan Africa. Twice-yearly doses have been shown to reduce mortality by 14 per cent in children one month to four years old. However concerns remain about perpetuating antimicrobial resistance. References Azithromycin to Reduce Mortality — An Adaptive Cluster-Rand…
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Keeping kids off screens can be easier said than done, especially when they’re so intertwined with our day-to-day lives. A paper has reviewed the evidence on how screen use in children under six can impact behaviour and cognitive outcomes – like attention, memory and learning. The researchers say while limiting time spent on screens is important, i…
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More than 60 per cent of Australian adults are living with overweight or obesity, putting them at increased risk of disease. So how can those risks be prevented and managed at both an individual and societal level? And how important are dietitians, especially with renewed interest in weight loss drugs? Guest Dr Terri-Lynne South, dietitian and GP…
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Meniere's disease is a chronic condition that causes tinnitus, vertigo and deafness. It typically starts in one ear, but can go on to affect both. At the moment there is no cure, only strategies to lower the chances of an attack and treatments to help manage the symptoms. It’s hoped gene therapy might be able to turn things around. Guests Steven Mo…
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A more severe variant of the mpox virus is spreading fast, already causing hundreds of deaths in Africa. The World Health Organization (WHO) has declared a public health emergency of international concern. We have vaccines against mpox, so what aren't we doing to slow the spread? Also, Australia is compared to other English-speaking countries and i…
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People with knee osteoarthritis are undergoing unnecessary tests and procedures, when exercise is often the best treatment. New clinical care standards have been released, putting the emphasis on non-surgical treatments for pain relief and mobility. Guest Dr Christopher Vertullo, orthopaedic knee surgeon and an Adjunct Professor at Griffith Univers…
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A majority of the world's population lives in cities. Our urban environments have changed rapidly, and a very different to the environments humans evolved in. This could mean we're not being exposed to the same diversity of 'good' microbes, that keep us balanced and healthy. Guest Dr Jessica Stanhope, epidemiologist at the University of Adelaide Ka…
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While humans and pathogens have waged war for millennia, even dangerous pathogens can be engineered to be helpful in the right hands. What are the qualities that make a microbe or virus so successful, and how can we harness them for good? Guest Jacinta Bowler, science reporter Associate Professor Joanne Macdonald, University of the Sunshine Coast R…
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Authorities in Victoria believe they've found the source of a Legionnaires' outbreak in Melbourne that has killed two people. What do we know about the disease, and what needs to be done to avoid outbreaks? References Outbreak of Legionnaires’ disease in metropolitan Melbourne Dispersion of Legionella bacteria in atmosphere: A practical source loca…
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There has been a heated – and at times harmful discussion about presumed sex differences in athletes competing at the Olympic Games. While unfounded, accusations against two female boxers have reignited a discussion that has been going on for over a century about who gets to compete, and against whom. We take a look at the evidence and explain why …
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Unions are calling for 10 days of reproductive leave for women going through menopause and perimenopause. They say older women are leaving the workforce early because a lack of support. But one expert argues there is no quality evidence to support this claim, and there are other issues at play. Guest Professor Susan Davis, endocronologist at Monash…
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