Best Schmidt Associates Podcasts (2024)

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#78 - Sam Hermitte, Texas Water Data 51:23

7h ago51:23

51:23

Send us a Text Message. In this conversation, Dr. Todd Votteler, Editor-in-Chief of Texas+Water, talks with Sam Marie Hermitte, Assistant Deputy Executive Administrator of Water Science and Conservation for the Texas Water Development Board, about utilizing data to support water management and conservation. Her responsibilities at the Texas Water D…

1
EP 141: Bringing genomics to the clinic with Lori Orlando, Associate Prof at Duke University 43:24

14h ago43:24

43:24

0:00 Intro to The Genetics Podcast 01:00 Welcome to Lori Orlando 03:00 Lori’s career: From mathematical modelling to genetics and family history 05:11 The study that revealed 20% of the general population is at a higher risk of disease than average and needs preventative care 07:36 The first five diseases that Lori started analysing through informa…

1
EP 140: The future of Electronic Health Records and data analysis with Ben Goldacre 52:51

7d ago52:51

52:51

0:00 Intro to The Genetics Podcast 1:00 Welcome to Ben Goldacre 02:22 Ben’s open data projects at the Bennett Institute and the challenges they aim to tackle 04:03 Using Electronic Health Records (EHR) to help the National Health Service improve care 06:18 The importance of software development within healthcare data and how to manage salary scales…

1
EP 139: Rare disease breakthroughs using tRNA with Michelle Werner, CEO of Alltrna and CEO-Partner of Flagship Pioneering 44:42

14d ago44:42

44:42

0:00 Intro to The Genetics Podcast. 01:00 Welcome to Michelle. 02:00 Sstop codon diseases and how are they characterised 03:45 Diseases caused by premature stop codons in haploinsufficient genes. 04:35 The role of transfer RNA technology in finding solutions for premature stop codon diseases. 06:16 How Alltrna is engineering tRNAs which can bind to…

1
Episode 23: A Legacy of Design and Education with Tom Neff, AIA, LEED AP 33:37

21d ago33:37

33:37

Join us as we explore the illustrious design career and remarkable creative leadership journey of Tom Neff, AIA, LEED AP. From growing up in Coshocton, Ohio to becoming a prominent figure in central Indiana’s K-12 architectural design community, Tom has contributed to encouraging equity and equality in K-12 schools. Learn more about his design stra…

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EP 138: Personalised medicine using microbiome models with Dr. Almut Heinken 40:22

28d ago40:22

40:22

0:00 Introduction 1:45 Almut’s research experience, including two recent publications on genome-scale metabolic reconstruction human microorganisms Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple…

1
#77 - Chad Berginnis, Floodplain Management & The Association of Floodplain Managers 53:56

1M ago53:56

53:56

Send us a Text Message. In this conversation, Dr. Todd Votteler, the Editor-in-Chief of Texas+Water, talks with Chad Berginnis, Executive Director of the Association of State Floodplain Managers (ASFPM), about the role of floodplain management in mitigating flood loss. As Executive Director of ASFPM, Berginnis frequently collaborates with FEMA, the…

1
EP 137: Mavis Machirori on promoting equity, diversity, and social justice in genomics research 41:40

1M ago41:40

41:40

0:00 Intro 1:30 Mavis’ career arc, from starting as a midwife to researching medical innovation and technology with an emphasis on advocacy and equity 7:00 Systemic issues that are easily overlooked in medical research and advancements Webinar: Participant Diversity: Increasing the Impact of Biomedical Research Webinar 10:00 Addressing Eurocentrici…

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#76 - Brian Richter, Water Scarcity 1:10:33

2M ago1:10:33

1:10:33

Send us a Text Message. In this conversation, Dr. Todd Votteler, the Editor-in-Chief of Texas+Water, talks with Brian Richter, president of Sustainable Waters, about the challenges posed by water scarcity. Brian Richter has been a global leader in water science and conservation for more than 30 years. As president of Sustainable Waters, a global or…

1
EP 136: Developments in ring chromosome 20 research and advocacy with Allison Watson 40:57

1M ago40:57

40:57

0:00 Introduction 2:00 Allison’s personal journey to researching epilepsy and ring chromosome 20 syndrome 4:00 Biggest challenges families face with ring chromosome 20 syndrome 11:00 Incidence and prevalence of r(20) syndrome, and how we can improve data reliability 21:00 Applying next generation sequencing to r(20) syndrome gene research 29:00 Eng…

1
EP 135: Integration of newborn sequencing programs into healthcare systems with Dr. Ingrid Holm 41:16

2M ago41:16

41:16

0:00 Introduction 1:30 Ingrid’s initial interests in genetics, paediatrics, and newborn screening 2:45 How the original BabySeq project, a pioneering newborn sequencing program got started, how it’s going, and the launch of BabySeq2 8:45 Lessons from BabySeq1 and goals for BabySeq2 10:30 Potential societal and long-term considerations for those inv…

1
Episode 22: Investing in Communities, Transforming Lives: The Leadership Story of Christamore House CEO La'Toya Pitts 29:02

2M ago29:02

29:02

Join Host Sarah Hempstead and Christamore House CEO La’Toya Pitts for an enlightening conversation on creative leadership. A driving force in the Haughville and Near Westside neighborhoods of Indianapolis, La’Toya has spearheaded efforts to provide child and youth educational services, senior programming, and life skills training to shape residents…

1
EP 134: Prenatal genetic testing and the future of AI in genetic counselling with Kira Dineen, host of DNA Today 40:44

2M ago40:44

40:44

0:00 Introduction 1:00 The backstory of how Kira first started DNA Today in 2012, when she was still in high school! 3:30 Some of Kira’s favourite topics she has discussed on DNA Today, including the legacy of Henrietta Lacks, and the story of a Glee actress with down syndrome 10:00 Kira’s best practices for podcasting, from over 10 years of experi…

1
#75 - Megan Lang, Wetlands Status and Trends 55:35

2M ago55:35

55:35

Send us a Text Message. In this conversation during American Wetlands Month, Dr. Todd Votteler, the Editor-in-Chief of Texas+Water, discusses wetland conservation and protection with Dr. Megan Lang, the Chief Scientist for the U.S. Fish and Wildlife Service National Wetlands Inventory Program. Dr. Lang leads the congressionally mandated national We…

1
EP 133: Insights into pharmacogenomics and increasing diversity in genomics research with Dr. Emma Magavern 39:17

2M ago39:17

39:17

0:00 Introduction 2:00 The value of an English Literature degree in designing and analysing research studies in medicine 3:45 Emma’s entrance to pharmacogenomics and her transition from practising physician to genetics research 6:00 How the East London Genes and Health program is increasing representation of diverse populations, namely South Asians…

1
EP 132: From mammoths to genome editing, trailblazing genetics with Dr. George Church 47:41

2M ago47:41

47:41

0:00 Introduction 1:00 George’s upcoming big projects, including developing full recycling, renewing energy, creating bioweather maps, and harnessing citizen science 6:45 Progress in engineering viral resistance in humans, including thoughts from pre- and post- pandemic 11:00 A swapped genetic code that prevents viral infections and gene transfer b…

1
EP 131: The potential of somatic genomics in drug discovery and development with Jake Rubens 44:57

3M ago44:57

44:57

0:00 Intro 0:40 Jake’s experiences as a serial entrepreneur starting five companies with a basis in genomic science 5:30 Opportunities for research and drug development in the realm of somatic science 9:20 Somatic evolution and how it provides valuable insights into disease mechanisms 12:30 Advantages and disadvantages of studying germline genome-w…

1
#74 - Katie Schmidt, The Dam Removal Movement 52:47

3M ago52:47

52:47

Send us a Text Message. In this conversation, Texas+Water Editor-in-Chief Dr. Todd Votteler discusses dam removal movement with Katie Schmidt, Associate Director of the National Dam Removal Program at American Rivers. Katie coordinates and implements the American Rivers' federal policy agenda for dam removal and works with our federal agency partne…

1
EP 130: Quarterly insights into noncoding variants and GWAS with Dr. Veera Rajagopal 51:56

3M ago51:56

51:56

Show Notes: 0:00 Introduction 1:20 How polydactyl mutations can inform research on non-coding variant mechanisms The importance of low-affinity binding between transcription factors and targets How these lessons can help us improve our understanding of drug and target discovery See Veera’s January round-up for more information: https://www.gwasstor…

1
EP 129: Patient advocacy for genetic ALS and FTD with Jean Swidler, Executive Director of End the Legacy 38:44

3M ago38:44

38:44

0:00 Introduction 0:45 Jean’s personal experiences with family members with genetic ALS 10:00 Jean’s thoughts on the barriers and facilitators to providing treatment for those with genetic ALS 13:20 Insights into C9orf72, a common genetic determinant of ALS, and how it can also be associated with FTD 16:10 Jean’s experiences as an active advocate f…

1
EP 128: Parkinson’s disease and precision medicine with Drs. James Beck and Ignacio Mata 50:18

3M ago50:18

50:18

0:00 Introduction 1:05 Insights into the PD GENEration’s (a programme from the Parkinson's Foundation) milestones and progress points for the upcoming year 3:30 The shifting attitudes and perspectives of neurologists and healthcare workers at the PD GENEration 5:50 Insights into Nacho’s work with the genetics of Parkinson’s disease 10:20 Barriers a…

1
#73 - Dr. Ralph Wurbs, Modeling River/Reservoir Systems for Water Management 57:28

3M ago57:28

57:28

Send us a Text Message. In this conversation, Texas+Water Editor-in-Chief Dr. Todd Votteler talks with Dr. Ralph Wurbs, professor in the Zachry Department of Civil Engineering at Texas A&M University, about modeling river and reservoir systems to support water management. Dr. Wurbs worked in the U.S. Army Corps of Engineers' water development progr…

1
EP 127: Insights into precision medicine, fatty liver disease, and minimally invasive diagnostic tools with Dr. Mazen Noureddin 39:10

3M ago39:10

39:10

0:00 Intro 0:25 Mazen’s lifelong commitment to furthering the field of precision medicine in liver disease research, fueled by a personal connection of his grandmother developing MASH cirrhosis 2:30 Breakthroughs in the field of metabolic dysfunction-associated steatotic liver disease (MASLD) since the beginning of Mazen’s career 5:30 The potential…

1
Episode 21: Empowering Student Futures: Dr. Dottie King on Shaping a Student-Centric Culture in Higher Education 36:49

4M ago36:49

36:49

Join host Sarah Hempstead for Luminate: Navigating the Unknown Through Creative Leadership as she interviews Independent Colleges of Indiana (ICI) President and CEO Dr. Dottie King. Since stepping into her role, Dr. King has advocated for Indiana’s 29 private, non-profit colleges and universities, drawing on her experiences as a professor and admin…

1
EP 126: Patient-led research for ultra-rare disease drug development with Julia Taravella, Executive Director of Rare Trait Hope Fund 39:41

4M ago39:41

39:41

0:00 Introduction 0:25 Julia’s personal experience with ultra-rare diseases within her family 10:25 The importance of increasing accessibility to genetic testing across populations to learn more about ultra-rare diseases 14:00 The origin story of Rare Trait Hope Fund 23:50 Current research and next steps in developing potential gene therapies for a…

1
EP 125: The future of UK Clinical Trial Policy: Innovation, integration, and game-changing legislation with Lord James O’Shaughnessy 45:23

4M ago45:23

45:23

0:00 Introduction 1:25 How Lord O’Shaughnessy became involved in scientific policy making and his path to writing the UK Commercial Clinical Trials Review. 04:05 How Lord O’Shaughnessy pivoted from education to a focus on life sciences 06:38 The biggest challenges Lord O’Shaughnessy faced during his time as Parliamentary Under Secretary for Health …

1
EP 124: How ReCode Therapeutics is pioneering tissue specific delivery of gene therapies for Primary Ciliary Dyskinesia with John Matthews 42:00

4M ago42:00

42:00

0:00 Introduction 01:10 How growing up in Malawi planted the seeds for John’s career in medicine and transition to therapeutic development 04:35 Why John focuses on rare diseases and conditions such as asthma 06:01 What has changed over the last decade in terms of treating and understanding asthma and the progress that genetics has enabled 07:31 Wh…

1
#72 - Scott Wright, Dam Removals & River Restoration 54:10

4M ago54:10

54:10

Send us a Text Message. In this conversation, Texas Water Journal & Texas+Water Editor-in-Chief, Dr. Todd Votteler, talks with Scott Wright, Principal Engineer for the River Design Group, about the impact of dam removals in river restoration efforts. Scott Wright is the Principal Engineer for the River Design Group in Corvallis, Oregon. Scott grew …

1
EP 123: The ethics of newborn genome screening: Actionable insights and beyond with Holly Peay, Senior Research Scientist at the Research Triangle Institute 45:34

4M ago45:34

45:34

0:00 Introduction 0:50 Holly’s background and career so far 03:30 Complex decision-making and multiple risk factors: Family history, genetics, phenotypes and beyond 07:05 Changes within the last decade to help people make complex, sometimes subjective, healthcare decisions 09:20 Impact on people: The RTI’s mission and the Early Check Study 13:45 Ne…

1
Episode 20: Revolutionizing Indy: Leonard Hoops' Creative Blueprint for Convention Success 33:09

5M ago33:09

33:09

Travel with us into the visionary world of Leonard Hoops, the president, and CEO of Visit Indy, and the driving force behind transforming Indianapolis into America’s top convention destination. From his Trinidadian roots to his rise in Indianapolis’ growing tourism industry, Leonard’s creative leadership and strategic vision have not only elevated …

1
#71 - Shaina Shay, The Water Report 29:34

5M ago29:34

29:34

Send us a Text Message. In this conversation, Texas+Water Editor-in-Chief Dr. Todd Votteler talks with the Owner and Editor of The Water Report, Shaina Shay. The Water Report is a monthly publication that provides detailed and timely coverage of the innovations and decisions shaping our water future. Shay has spent more than a decade developing exp…

1
EP 122: Building genome-scale engineered cells for biotechnology with Leslie Mitchell, Co-founder and CEO of Neochromosome 35:55

5M ago35:55

35:55

Summary: 0:00 Introduction 01:01 How Leslie got into the field of synthetic biology and engineering, and her career journey so far 02:45 What Leslie accomplished during her postdoc and recent transformations in the field of genomics 05:57 The impacts of non-coding regions of the genome and the outcome of deletions 08:20 How long it takes to make ch…

1
EP 121: Breakthroughs and insights in ALS research with Dr. Michael Benatar 44:10

5M ago44:10

44:10

Summary: 0:00 Introduction 0:50 Reflections from the 34th International Symposium on ALS/MND in Basel 1:50 Michael’s professional journey, initial challenges he encountered, and how the field of neurology has evolved over the years 3:10 An introduction to the ALS landscape, including its presentation, the genes involved, and potential treatment opt…

1
EP 120: Exploring the frontiers of gene therapy and AAVs with Dr. Nicole Paulk, CEO and Founder of Siren Biotechnology 43:47

5M ago43:47

43:47

0:00 Introduction to Dr. Nicole Paulk, a pioneer in AAV research and the founder of Siren Biotechnology 0:50 The moments that shaped Nicole’s career path and her passion for gene therapy and AAV research 9:20 Nicole’s academic research career and her transition from academia to the biotech industry 23:00 The story behind the founding of Siren Biote…

1
EP 119: Revolutionising drug discovery: how the Pharma Proteomics Project is combining genetic and proteomic data with Chris Whelan 38:25

5M ago38:25

38:25

0:00 Introduction 01:00 Chris’ background and career to date 02:10 What is the Enigma Project? 04:48 How is genetics being applied to drug discovery today and how does proteomics fit in? 09:23 When the UKBiobank Pharma Proteomics Project began and how long it took to set up 10:57 54k UK Biobank participants tested - discussion of findings 14:33 The…

1
#70 - Rachel Fern, The State of Texas Wetlands 41:34

6M ago41:34

41:34

Send us a Text Message. In this conversation, Texas+Water Editor-in-Chief Dr. Todd Votteler talks with Dr. Rachel Fern, Statewide Wetland Program Leader for the Texas Parks and Wildlife Department, about the state of wetlands in Texas, including their history, current status, and future challenges. Fern coauthored a recent article in the Texas Wate…

1
EP 118: The role of genetics in drug discovery and development with Dr. Matt Nelson 42:56

6M ago42:56

42:56

Summary: 0:00 Introduction 5:45 Lessons learned from 15 years at GSK: How has genetics and drug discovery evolved over time? 8:10 Matt’s seminal 2015 paper: Quantifying the impact of human genetic evidence on the probability of success in drug development 11:40 Which types of genetic evidence are the best drivers of success in clinical trials? 13:3…

1
The Art of Airborne Leadership with Mario Rodriguez 31:01

6M ago31:01

31:01

Embark on an intimate exploration of leadership and perseverance with Mario Rodriguez, the visionary leader at the Indianapolis Airport Authority. His tale, a tapestry woven from his parents' daring escape from Cuba and their indomitable spirit to triumph in a foreign land, is nothing short of cinematic. As we chat with Mario, you'll experience the…

1
EP 117: Wendy Chung: whole genome newborn screening and other big opportunities in genomic medicine. 47:51

6M ago47:51

47:51

Summary: 0:00 Introduction 1:45 Wendy’s early career looking into the genetics of diabetes through mouse models 6:23 A high altitude view: Cutting through hype to spot the next wave of game-changing technology 8:03 The role of policy and communication: how Wendy’s work goes beyond the lab to create real-world impact 11:20 Wendy’s choice to do an MD…

1
EP 116: Genetics and Medicine: Clonal hematopoiesis, genomics in healthcare, and a new discovery in APOL1 kidney disease with Dr. Alex Bick 52:34

6M ago52:34

52:34

0:00 Introduction 4:23 Insights into clonal hematopoiesis from the pioneering Framingham Heart Study 8:30 Linking clonal hematopoiesis to cancer and cardiovascular health 11:22 Interplay of germline and somatic variants in clonal expansion 17:20 How the rate of clonal expansion can provide insights into cancer and cardiovascular risk 19:00 How clon…

1
EP 115: The Biggest Stories of 2023 with Dr. Veera Rajagopal (Part 2) 1:35:11

6M ago1:35:11

1:35:11

In the second instalment of our annual round-up episode, we welcome back Dr. Veera Rajagopal to cover the biggest stories in genetics and precision medicine of the last 12 months. Don’t forget to give the first instalment of our 2023 round-up a listen. Veera is a scientist at Regeneron with an interest in human genetics and drug target discovery in…

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EP 114: The Biggest Stories of 2023 with Dr. Veera Rajagopal (Part 1) 1:10:35

7M ago1:10:35

1:10:35

0:00 Introduction 1:30 Veera’s personal highlights of 2023 Publication in Nature Genetics: Rare coding variants in CHRNB2 reduce the likelihood of smoking, an exome-wide association study identifying rare coding variants in CHRNB2 that may reduce the likelihood of smoking. Designing cover art Genetic links to neural circuits and their role in addic…

1
EP 113: Harnessing human genetics to discover co-evolved small molecule medicines with Dr. Jason Park, CEO of Empress Therapeutics 44:31

7M ago44:31

44:31

In this episode of The Genetics Podcast, we welcome Dr. Jason, founder and CEO of Empress Therapeutics, a Flagship Pioneering company. Join us as we discuss how human genetics can identify small molecules with therapeutic potential that are already created by our bodies, paving the way for faster discovery of new medicines. Summary: 0:00 Intro 1:20…

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#69 - Kelley Cochran, Groundwater Conservation Districts 25:31

8M ago25:31

25:31

Send us a Text Message. In this conversation, Texas+Water Editor-in-Chief Dr. Todd Votteler talks with Kelley Cochran, General Manager of the Guadalupe County Groundwater Conservation District, about the role Groundwater Conservation Districts play in supporting the state's water management and planning efforts. Cochran joined the district in 2014 …

1
EP 112: Making the leap: the scientists collaborating to transform genetic targets into next generation treatments, with David Ochoa 41:36

8M ago41:36

41:36

This week on The Genetics Podcast Patrick is joined by David Ochoa, Platform Coordinator at Open Targets. They discuss how the Open Targets platform is enabling game-changing collaboration between academic research and big pharma. Working with partners including Sanofi, GlaxoSmithKline, Bristol Myers Squibb, Genentech and Pfizer, Open Targets power…

1
Advocating For Art: A Leadership Conversation with Julie Goodman, President and CEO of the Indy Arts Council 39:31

8M ago39:31

39:31

How does the central Indiana arts community navigate and survive during challenging times? Learn how as Julie Goodman, the tenacious and inspiring President and CEO of the Indianapolis Arts Council explains. Follow along as she underlines why the arts are vital to mental well-being and how they can fortify communal bonds. But the power of art exten…

1
#68 - James Perry, Detecting Water Leaks & Problem Dams Using Innovative Technologies 29:18

8M ago29:18

29:18

Send us a Text Message. In this conversation, Texas+Water Editor-in-Chief Dr. Todd Votteler talks with James Perry, Executive Vice President of the EarthWorks Division of ASTERRA, about innovative remote sensing technologies to support water management. Perry has spent over 30 years driving disruptive innovation. In both start-ups and Fortune 500 c…

1
EP 111: Combining human and machine intelligence in protein engineering with Dr. James Field, CEO of LabGenius 35:34

8M ago35:34

35:34

In this episode of The Genetics Podcast, we welcome Dr. James Field, founder and CEO of LabGenius. Join us as we delve into LabGenius' cutting-edge approach that utilises machine learning, artificial intelligence, and sophisticated robotics to advance antibody discovery and drug development. As a bonus, learn about James’ path from scientist to CEO…

1
#67 - Karrigan Börk, Protecting Wetlands via the Clean Water Act 1:06:17

8M ago1:06:17

1:06:17

Send us a Text Message. In this conversation, Texas+Water Editor-in-Chief Dr. Todd Votteler talks with Karrigan Börk, Acting Professor of Law at the University of California Davis (UC Davis) School of Law, about federal efforts to protect wetland habitats. Börk graduated from Stanford Law School in 2009 and completed his Ph.D. dissertation in Ecolo…

1
EP 110: Educating the next generation of genomics talent, and the intersection of genetics and environment in cancer with Barbara Kraatz Fortini 35:41

8M ago35:41

35:41

On this episode of The Genetics Podcast we welcome Dr. Barbara Kraatz Fortini, Associate Professor of Genetics at Keck Graduate Institute (KGI). Tune in to learn about Barbara's research on non-coding variants in colorectal cancer and the interplay between genetics and the environment on lifetime cancer risk. As the Program Director for the MS in H…

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