Brought to you by the D.R.E.S.S. Syndrome Foundation and hosted by Connie Stevens. An educational podcast on the severe adverse drug reaction known as D.R.E.S.S. Syndrome. Drug Reaction with Eosinophilia and Systemic Symptoms is often under-recognized and misdiagnosed. We talk with patients who have been touched by this horrific condition and experts who are working to prevent it, treat it, and create better awareness.
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Welcome to the monthly Primary Care Pod from Red Whale – join GPs Nik Kendrew and Caroline Greene as each month they discuss a roundup of four key topics for primary care clinicians, which can also be found in our popular free Pearls . We look at the evidence, the guidelines and the media coverage and make learning together as a primary care community as relaxing and enjoyable as possible. We invite you to nominate your primary care heroes and share your “best intentions” stories. So, grab a ...
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Which of the risks associated with prescribing systemic quinolones concerns you the most?
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Grab your trainers, your dog lead or a cuppa and join us for some free CPD as we have another relaxed round up of recent Red Whale primary care Pearls of wisdom. This month, Nik and Caroline discuss: Acute aortic dissection. What would you do if you suspected it? The limping child. Who goes in to hospital? Who might be able to be managed in primary…
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Can you name the five eating disorder subtypes?
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Grab your trainers, your dog lead or a cuppa and join us for some free CPD as we have another relaxed round up of recent Red Whale primary care Pearls of wisdom. This month, Nik and Caroline discuss: Recent changes with progestogen-only pills. How is the new POP different from the others? Erectile dysfunction, and what is Eroxon? The available evid…
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Is there post-exposure prophylaxis for measles?
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Grab a cuppa and join us for some free CPD as we have another relaxed round up of recent Red Whale primary care Pearls of wisdom. This month, Nik and Caroline discuss: Actively beating the new year blues. How can we build conversations about physical activity into our consultations? Scabies surge: how do you spot it and manage it? ( And can you get…
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In which scenario should you NEVER use a pulse oximeter?
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Grab a cuppa and join us for some free CPD as we have another relaxed round up of recent Red Whale primary care Pearls of wisdom. This month, Nik and Caroline discuss: Galleri: will this blood test revolutionise cancer diagnosis? We review the evidence behind it and ask: How effective is it when cancer is suspected, and how effective is it for popu…
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Join us for a relaxed round up of recent Red Whale primary care Pearls of wisdom. This month, Nik and Caroline discuss: Healthy ageing: adding quality to years? What does ‘healthy ageing’ look like? What are the 3 trajectories of ageing? How can we work as a primary care team to promote the basics that increase the chance of healthier ageing? Preve…
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Re: balance and burnout prevention. Plus HRT, COVID and endometriosis.
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Join us for a relaxed round up of recent Red Whale primary care Pearls of wisdom. This month, Nik and Caroline discuss: HRT for primary prevention? About 25% of menopausal-age women have no symptoms and so do not require HRT to treat vasomotor or other hormone-related issues. However, they may be influenced by media messages suggesting that HRT cou…
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A magic spell that will open your (itchy) eyes to tics, Tourette’s and tackling the latest drug swaps…
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Join us for a relaxed round up of recent Red Whale primary care Pearls of wisdom. This month, Nik and Caroline discuss: GLP-1 mimetics shortages: tackling drug swaps. The headline grabbing GLP-1 mimetics are rarely out of the news- most recently due to supply issues for people with type 2 diabetes. How do we deal with this? Tics and Tourette’s synd…
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Join us for a relaxed round up of this month’s Red Whale primary care Pearls of wisdom. This month, Nik and Caroline discuss: Bites: human, animal and insect. It’s still that time of year when the triage list is full of: “Bite ? Infected”. We look at all things bite related including assessment, management and who needs antibiotics. DeQuervain’s te…
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Avoid alcohol... and hot headed rash decisions?!
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Join us for a relaxed round up of this month’s Red Whale primary care Pearls of wisdom. This month, Nik and Caroline discuss: Fetal alcohol spectrum disorder: one child in every class at school is potentially affected and unsupported. What can we do about this, and why is discussing alcohol in pregnancy a taboo? Varicella zoster (chicken pox) and N…
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Who needs a holiday? How about some free CPD by the sea?...
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Join us for a relaxed round up of this month’s Red Whale primary care Pearls of wisdom. This month, Nik and Caroline discuss: Intrauterine systems, and how they just got a bit simpler… Diabetes and frailty: how we need all our primary care superpowers across the whole multiprofessional team to think about the big picture! Joining with Up: The Adult…
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Save a life, change a life, quality of life…
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Join us for a relaxed round up of this month’s Red Whale primary care Pearls of wisdom. This month, Nik and Caroline discuss: Would you spot serotonin syndrome? Lower urinary tract symptoms: prescribing pointers for 5ARIs BMI and ethnic groups Anorexia, nutrition and hydration in the last days of life Infantile spasms: would you be confident to spo…
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To vape or not to vape? - and other primary care questions...
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Join us for a relaxed round up of this month’s Red Whale primary care Pearls of wisdom. This month, Nik and Caroline discuss: Menopause in the media: How our HRT GEMS can help the whole team Swap to stop: can e-cigarettes help smokers quit. Chronic diarrhoea: could it be microscopic colitis? How to assess and manage postural hypotension And hear a …
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Join us for a relaxed round up of this month’s Red Whale primary care Pearls of wisdom. This month, Nik and Caroline discuss: NICE guidance on semaglutide for obesity “Light bulb” conditions - we explore neuroendocrine tumours. Moral injury: looking afters our teams and ourselves! A structured approach to chronic cough in adults. And find out about…
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Episode 1: Izzy's Story: "Always Blame the Drug"
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For 16-year-old Izzy McKinney, a course of treatment with the antibiotic Bactrim first led to fevers and a bad rash. But that was just the beginning. What no one realized was that Izzy was suffering from a severe case of D.R.E.S.S: Drug Reaction with Eosinophilia and Systemic Symptoms. This introductory episode tells the tragic story of how DRESS s…
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Episode 2: How D.R.E.S.S. Got its Name. A Conversation with Dr. Vincent Descamps
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Medication-induced drug disorders have been evident for nearly a century and labeled with a variety of names. French dermatologist Dr. Vincent Descamps, who has been at the forefront of DRESS syndrome since the mid-1990s, joins us to review this historically misunderstood and under-reported illness. We'll also discuss the history of how an internat…
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Episode 3: Hannah Was Here: A Fatal Case of Minocycline-Induced D.R.E.S.S. Syndrome
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Hannah's mother and long-time DRESS advocate, Nancy Szakacsy tells of her daughter's struggle against a fatal case of DRESS syndrome that was triggered by the antibiotic Minocycline. The devastation of losing Hannah, and the obvious lack of information and resources for families like hers inspired Nancy to write a book about her daughter's illness.…
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Episode 4: The Link Between Viruses and Severe Adverse Drug Reactions: A Discussion with the Experts
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International severe adverse drug reaction experts, Dr. David Ostrov and Dr. Vincent Descamps, talk to us about the immune response that occurs in DRESS syndrome as well as how antiviral and steroid therapies are often indicated in fighting this condition. We also hear from Kent Van Donge about the importance of a team approach in the treatment of …
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Episode 5: Risk Factors and the First Signs: An Interview with Dr. Elizabeth Phillips
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In this episode, we talk with world-renowned DRESS Syndrome expert, Dr. Elizabeth Phillips. She and her colleagues at Vanderbilt University Medical Center are working to better understand the genetic factors that increase a patient's risk for developing life-threatening, immune-mediated drug reactions - with a focus on simple, inexpensive diagnosti…
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Theresa Stickney shares the story of her long and complicated course of illness with DRESS Syndrome, triggered by the drug Vancomycin. Since recovering, she has been inspired to share what she knows, both as a nurse and a patient - helping other patients, caregivers, doctors and researchers better understand this often misdiagnosed and difficult to…
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Episode 7: "A Lot of Parallels Between Our Lives"
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From opposite ends of the U.S., two mothers share a common bond. They both know what it’s like to sit at a child’s hospital bedside, desperately searching the world over for the medical information that could save their daughter’s life. When the resources they needed weren’t available, they took matters into their own hands to create them. While wo…
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Episode 8: "Is This DRESS?" An Interview with Dr. Arash Mostaghimi
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Life-threatening drug reactions often present with a rash, so dermatologists may be the first line of defense for treatment. Dr. Arash Mostaghimi, a dermatologist at Harvard Medical School’s Brigham & Women’s Hospital, draws on his experience with DRESS patients in teaching medical students about this complex and often misunderstood condition. Inte…
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Episode 9: Surviving DRESS: "You Really Need A Team"
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When Linda Wondrack was diagnosed with rheumatoid disease in 2015, she never imagined that her treatment with Sulfasalazine would end up leaving her even more severely ill. In the wake of a complicated recovery from DRESS, she shares the physical and psychological toll this delayed drug reaction can take... and the importance of self-advocacy and s…
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Episode 10: "Patients Need to Make A Lot of Noise...Demand an HHV-6 Test"
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Viruses from previous infection may stay dormant in our bodies for years - sleeping away the time, never causing any trouble. However, in immunosuppressed conditions like DRESS, the virus may awaken and wreak havoc. Viral reactivation of human herpesviruses, in particular HHV-6, are a known phenomenon of DRESS, occurring in up to 50% of patients. W…
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Episode 11: The Unique Nature of This Virus: HHV-6
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German virologist, Dr. Bhupesh Prusty, discusses his research on the human herpes virus, HHV-6, and its important role in many medical conditions including DRESS syndrome. We then hear from Japanese dermatologist and DRESS expert, Dr. Hideo Asada, about the long-term complications associated with HHV-6 and DRESS. Interview: Dr. Bhupesh Prusty (Mole…
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