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The Curious Clinicians

The Curious Clinicians

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The Curious Clinicians is a medical podcast that asks "why?". Why do diseases present in certain ways? What are the mechanisms of treatments we use? Why does the human body function as it does? Join us to explore these questions and many more.
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Iron Matters

Haemochromatosis Australia

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IRON-MATTERS is a series of interviews by and for medical and health practitioners focusing on hereditary haemochromatosis. The series is intended to provide general practitioners with in-depth information about this genetic chronic condition. Topics include - diagnosis in general practice with GP Dr Robert Menz- the genetics of haemochromatosis with clinical geneticist Prof martin Delatycki- haemochromatosis and the liver with gastroenterologist Prof John Olynyk- haemochromatotic arthropath ...
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"Things work out until they don't." Ain't life a bitch? Maybe we should celebrate it nonetheless. Friends With Deficits is a fun, honest, and sometimes brutal exploration into the human condition, often over drinks. Host Adam Sultan talks with old friends and friends-to-be who are dealing with unusual, rare, or strange predicaments that bring life into focus. After all, we're all gonna die--would you like that with a twist?
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Instead of "Why do we...?" this week the Curious Clinicians answer a "Why don't we?" question: why don't we use steroids in acute pancreatitis? Watch this episode on our new YouTube channel here, and read the show notes here! Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 …
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Miss Layla is an interdisciplinary artist and self-taught perfumer based in L.A. Her interest in fragrance and olfactive endeavors began as a small child when she learned how to cook and “taste shapes”. Later in life, Layla came to know that she had synesthesia, which she harnesses to her advantage when formulating perfume. After contracting COVID-…
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The Curious Clinicians answer a fascinating historical perspective: what was the role of antibiotics in ancient society? Watch this episode on our new YouTube channel here, and read the show notes here! Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). Audio edited by…
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The Curious Clinicians answer a sweet question about a new medication: Why do SGLT2 inhibitors cause erythrocytosis? Watch this episode on our new YouTube channel here, and read the show notes here! Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). Audio edited by Cla…
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The Curious Clinicians answer a gigantic oncologic and evolutionary question: Why don't elephants get (as much) cancer? Watch this episode on our new YouTube channel here, and read the show notes here! Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). Audio edited by …
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Hold your breath for this one! The Curious Clinicians answer a puzzling pulmonary physiology question: Why can systemic pulmonary vasodilators worsen hypoxemia in COPD-associated pulmonary hypertension? Watch this episode on our new YouTube channel here, and read the show notes here! Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non…
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The Curious Clinicians answer an early curiosity question: Why do my fingers wrinkle when I take a bath? Watch this episode on our new YouTube channel here, and read the show notes here! Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). Audio edited by Clair Morgan of…
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In this episode from our archives, originally posted on September 16, 2020, The Curious Clinicians examined why the savory flavor umami is SO DELICIOUS. Dig in! Show notes: https://curiousclinicians.com/2020/09/16/episode-9-why-is-umami-so-delicious/ CME: https://vcu.cloud-cme.com/course/search?p=4000&curriculum=Curious%20Clinicians Audio edited by…
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The Curious Clinicians are on tap to ask, why does chronic alcohol use cause macrocytosis? Read the show notes here. Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). Audio edited by Clair Morgan of Nodderly.com. Medical student Giancarlo Buonomo is our producer.…
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Welcome to NephMadness 2024! In collaboration with Things We Do For No Reason (TWDFNR), we are excited to promote the start of this amazing medical education opportunity. Inspired by the "March Madness" college basketball tournament, NephMadness is a "a free online, CME-granting, evidenced-based, noncommercial learning initiative that leverages the…
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The Curious Clinicians examine why the genetic mutations leading to hereditary hemochromatosis might have offered an evolutionarily advantage to our Neolithic ancestors. The answer relates to an old breakfast stalwart- cereal and milk! Read the show notes here. Audio edited by Clair Morgan of Nodderly.com. This episode is sponsored by Audible! New …
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Life transformation coach and licensed psychotherapist Amanda Wallingsford discusses her journey with childhood trauma and recent family loss, and the tools she has used to mitigate PTSD, depression, and grief. Coaching Website: www.AlignandEmbody.com Book Website: www.EmbodyYourWorth.com Therapy Website: www.PositiveChangesCounseling.net Instagram…
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On this episode from our archive, originally posted on March 15, 2022, The Curious Clinicians examine why cirrhosis predisposes to SBP, and why bacterial translocation across the bowel wall into ascites doesn’t actually occur! Read the show notes here. Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours…
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The Curious Clinicians investigate the history and mechanisms of how thalidomide caused embryopathy in the late 1950s and early 1960s in over 10,000 babies across the world. Read the show notes here. Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). Audio edited by Cl…
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On this episode from our archive, originally posted on February 16, 2022, The Curious Clinicians investigate why antiphospholipid antibodies can be falsely positive during acute illness or thrombosis. Read the show notes here. Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5…
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In this episode, we investigate the reasons why we don't (and don't need to) transfuse to normal hemoglobin levels. Read the show notes on our website here. And subscribe to our new Substack! Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). Audio edited by Clair Morg…
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Ok, so you've got issues. Big issues. Weird issues. You've even been on Friends with Deficit to discuss said issues. That can't be all there is! In this episode, we take a trip down memory lane and focus on the upside of the downside of, well, being a human being. Included are excerpts from previous guests Jeff Hoskins, Spectra Stewart, Special K, …
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The Curious Clinicians are currently on a holiday break, but we'll be back with new content in 2024! In the meantime, we hope you enjoy this episode from our archive, originally posted December 10, 2022. We told the story of a tiny carbohydrate called alpha-gal, delving into unsettling meat allergies after tick bites, ancient viruses, allergic reac…
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Austin musician Kat O’Kane of Pocket 20 shares her story of complex Post-Traumatic Stress Disorder, generational trauma, and her healing journey and coping strategies. More about Kat and Pocket 20: https://www.pocket20music.com/ Recommended reading: What My Bones Know, by Stephanie Foo The Whole-Brain Child, by Daniel J. Siegel and Tina Payne Bryso…
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In this episode, we examine how sickle cell trait protects against malaria, in multiple ways. Read the show notes on our website here. And subscribe to our new Substack! Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). Audio edited by Clair Morgan of Nodderly.com. Ou…
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Today we reach back into The Curious Clinicians archives, just in time for Thanksgiving. In this episode, originally posted in November 2021, Hannah, Avi, and Tony examine whether tryptophan from turkey actually causes the infamous Thanksgiving food coma. The answer might surprise you... Check out the episode's show notes here. Click here to obtain…
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In this episode, we explore why ACE inhibitors treat scleroderma renal crisis so effectively (and why bilateral nephrectomy used to be the treatment of choice…). Read the show notes on our website here. And subscribe to our new Substack! Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC …
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In this episode, The Curious Clinicians ask why a ketogenic diet can help control seizures in refractory epilepsy? Read the show notes on our website here. And subscribe to our new Substack! Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). Audio edited by Clair Morga…
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For this episode, The Curious Clinicians ask why patients with bioprosthetic heart valves don't require immunosuppression? Read the show notes on our website here. And subscribe to our new Substack! Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). Audio edited by Cla…
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On this episode, The Curious Clinicians learn about why hyperthyroidism is associated with atrial fibrillation. Read the show notes on our website here. And subscribe to our new Substack! Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). Audio edited by Clair Morgan o…
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On this episode, The Curious Clinicians explore the liver's incredible ability to regenerate after injury or resection. Read the show notes on our website here. And subscribe to our new Substack! Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). Audio edited by Clair …
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This week, The Curious Clinicians are bringing back an episode from the archive that was originally posted in December, 2021. Tony joined Dr. Adam Rodman as a guest on the Bedside Rounds podcast. We were thrilled to share that episode here. How can we medically tell whether or not someone is alive or dead? The answer is more complicated than you’d …
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On this episode, The Curious Clinicians investigate why alcohol both causes a burning sensation when you first swallow it (hint: the mechanism has something to do with chili peppers) and why you get a general sense of total body warmth within the next few minutes. Read the show notes here. Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours…
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On this episode, The Curious Clinicians examine an intriguing question - why are babies protected from infection and colitis by C. Diff? We'll touch on factors relating to immunology, microbiology and human development. Read the show notes here. Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours), or A…
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On this episode, The Curious Clinicians are joined by Dr Christopher Worsham, co-author of a fascinating and insightful new book, Random Acts of Medicine, which explores the use of natural experiments to better understand healthcare and is now out in hardcover! Audio edited by Clair Morgan of Nodderly.com.…
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This week, we reach back into the archive for an episode from 2021 (the first in a two-part series related to the eyes) where Tony, Hannah, and Avi explored why Wilson disease can present with Kayser-Fleischer corneal rings. Remember to pick up CME/MOC credit just for listening to the episode! Check out the show notes for this episode and read Avi'…
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On this episode, The Curious Clinicians dive into musical history, examining what might have caused German composer Ludwig van Beethoven's infamous deafness. Read the show notes here. Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). Audio edited by Clair Morgan of No…
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In this episode, The Curious Clinicians learn about why pneumonia takes weeks to resolve on chest x-ray, whereas symptoms generally resolve much sooner. Read the show notes here. Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). Audio edited by Clair Morgan of Nodderl…
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In this episode, The Curious Clinicians examine why upper gastrointestinal bleeding raises BUN. The answer involves experiments where participants were asked to drink blood (!) and the 700 sextillion (7 x 1023) amino acids that comprise the hemoglobin content in a liter of blood. Read the show notes here. Click here to obtain AMA PRA Category 1 Cre…
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That’s right, Voltage-Gated Potassium Channel Antibody Associated Peripheral Nerve Hyperexcitability Syndrome—It’s a mouthful of a disorder! Austin musician Andy Nolte (Como Las Movies, Scott Strickland Band, Super Creeps) shares a rare and extremely long-titled condition that causes a ton of neuropathic pain, but may have made him a better musicia…
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In this episode, The Curious Clinicians tackle why alpha-1 antitrypsin deficiency can cause chronic liver disease. Read the show notes here. Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). Audio edited by Clair Morgan of Nodderly.com. This episode is sponsored by Be…
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In this episode, The Curious Clinicians investigate whether atrial fibrillation should be considered a risk factor for PE. Read the show notes here. Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours). Audio edited by Clair Morgan of Nodderly.com. This episode was sponso…
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Austin multi-instrumentalist and tribute band aficionado David Houston discusses his musical career and the birth condition that may have shaped it. More on David and his bands: https://campsite.bio/dhvoice The Eggmen: https://eggmen.com/home Mock Lobster: https://www.facebook.com/Mocklobsteratx?mibextid=LQQJ4d Yacht Z: https://yachtzrock.com/ Cold…
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In this episode, The Curious Clinicians investigate the mysterious blood brain barrier, and how dexamethasone has a seemingly miraculous ability to treat cerebral edema caused by brain tumors. Read the show notes here. Click here to obtain AMA PRA Category 1 Credits™ (0.5 hours), Non-Physician Attendance (0.5 hours), or ABIM MOC Part 2 (0.5 hours).…
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