Best Hemochromatosis Podcasts (2024)

1
Pirtobrutinib plus venetoclax with or without rituximab in relapsed/refractory CLL; murine models of erythroid 5ALA synthesis disorders; targeting PKCa in diabetes and hemochromatosis 23:17

9d ago23:17

23:17

In this week's episode we’ll discuss the safety and efficacy of pirtobrutinib with or without rituximab in relapsed/refractory CLL; learn more about erythroid 5ALA synthesis disorders and their conditional synthetic lethal dependency on pyridoxine; and discuss how targeting PKC alpha alleviates iron overload in diabetes and hemochromatosis through …

1
Ep 152 Hemochromatosis: Ironing out the details 1:19:18

14d ago1:19:18

1:19:18

For life on this planet, iron is not optional. It is essential. When our iron levels are low, we can get sick, and when they get really really low, we can even die. But you know what they say, too much of a good thing can be a bad thing. In the case of iron, the genetic condition hemochromatosis is often to blame for iron overload, but why is too m…

1
Special Episode: Dr. Charan Ranganath & Why We Remember 1:03:27

15m ago1:03:27

1:03:27

How is it that we can’t remember where we put our keys or the name of the person we just met, but we can recall in excruciating detail the embarrassing interaction we had at the grocery store ten years ago? Sometimes it seems like our memory works against us more than it does for us. But, as it turns out, this aspect of our memory is more a feature…

1
Unlock Greater Energy and Less Frazzle with Paraxanthine and Drink Update l Why Coffee is Reducing Cognitive Performance, Sleep Quality, Energy Production and so much more with Shawn Wells, the World's ... 1:25:24

13h ago1:25:24

1:25:24

In this episode, we sit down with Shawn Wells, "The World's Greatest Formulator," to explore the hidden detriments behind caffeine addiction and how it may be negatively impacting our health and energy levels. He shares more on paraxanthine, a novel compound that could offer a better solution for those seeking enhanced focus and alertness without t…

1
A novel tripartite fusion drives treatment resistance in atypical APL; managing iTTP without TPE; hope for motherhood after allogeneic HCT 18:30

4d ago18:30

18:30

In this week's episode we’ll discuss a novel tripartite fusion drives treatment resistance in acute promyelocytic leukemia. In some patients with atypical APL, these novel retinoic acid receptor gene fusions result in truncation of the ligand binding domain of the retinoic acid receptor protein, resulting in non-responsiveness to treatment with all…

1
Ep 153 Alpha-Gal Syndrome: A tick bite gone bad 1:15:58

7d ago1:15:58

1:15:58

One day, you’re enjoying a beautiful hike through the tall grass. A few months later, you find yourself in anaphylaxis from a post-hike hamburger. The culprit: a tick bite. In this much-requested episode, we take on alpha-gal syndrome, the red meat allergy triggered by the bite of a tick. Sometimes science is stranger than fiction. How exactly does…

1
Why We All Need More & Better Minerals with Barton Scott of Upgraded Formulas l Using Nano-Particle Technology to Optimize Nutrient Absorption and Reduce Deficiencies for Optimal Health 59:26

7d ago59:26

59:26

In this episode, we dive into the critical role minerals play in overall health with Barton Scott, founder and CEO of Upgraded Formulas. Barton shares why many of us are mineral deficient, even with a healthy diet, and how these deficiencies can impact everything from energy levels to cognitive function. He explains the importance of choosing high-…

1
Your Healthiest, Non-Toxic Home Yet with Andy Pace of Green Design Center l The 3 Top Toxic Offenders in Your Home, How to Address Mold and VOCs, and What to Look For When Buying a New House 1:01:55

14d ago1:01:55

1:01:55

In this episode, we sit down with Andy Pace of the Green Design Center to explore how our homes might be contributing to poor health, especially for those suffering from multiple chemical sensitivity (MCS). Andy explains the hidden dangers in common building materials like carpeting and paint, shedding light on how these products release harmful ch…

1
Transplant outcomes in pediatric Fanconi anemia; hepatic Foxo1 regulates iron homeostasis; clinical networks improve APL outcomes in Latin America 18:42

16d ago18:42

18:42

In this week's episode we'll discuss outcomes following hematopoietic stem cell transplantation in pediatric patients with Fanconi anemia. Then, we'll learn about how new research shows that the transcription factor Foxo1, commonly associated with glucose metabolism, regulates hepcidin expression and systemic iron homeostasis. Finally, in Latin Ame…

1
Special Episode: Dan Egan & The Devil’s Element 55:10

21d ago55:10

55:10

Phosphorus is an element that wears many faces. Its overuse as a fertilizer has polluted freshwater ecosystems, transforming rivers and lakes from thriving communities to lethal zones devoid of life. Its role as an explosive has brought fiery death and suffering to many during times of war. And its dwindling global supply poses an existential threa…

1
The Greatest Antioxidant in the World! What is Carbon60 with Chris Burres, Founder of MyVitalC 1:08:05

21d ago1:08:05

1:08:05

In this episode, we interviewed Chris Burres, co-founder of MyVital C, about Carbon60 (C60), the Nobel Prize winning molecule that is gaining attention for its powerful health benefits. Chris shares how this unique molecule has been shown to possess potent antioxidant and anti-inflammatory properties in the body. He also discusses groundbreaking re…

1
CD8+ T-cell differentiation and treatment response in AML; ATM germline pathogenic variants affect cancer outcomes in ataxia-telangiectasia; efficacy of a selective menin-KMT2A inhibitor in KMT2A- and ... 22:42

25d ago22:42

22:42

In this week's episode we’ll discuss how CD8+ T-cell differentiation and dysfunction inform treatment response in acute myeloid leukemia; learn more about the effect of ATM germline pathogenic variants on the outcomes in children with ataxia-telangiectasia and hematological malignancies; and discuss the preclinical efficacy of a potent, selective m…

1
Ep 151 Stethoscope: Lub dub 1:24:26

28d ago1:24:26

1:24:26

The stethoscope. It’s iconic. You’re playing Pictionary and you pull the “doctor” card? Easy - sketch a stethoscope. Need a last-minute Halloween costume? Easy - throw a stethoscope around your shoulders. Google image search “doctor” and you can count the number of stethoscope-less doctors on one hand. How did this instrument become so emblematic o…

1
Biohacking Breast Implant Illness with Dr. Kayte Susse l Understanding Personal Risks, Supporting Capsule Formulation, Finding Explant Surgeons for En Bloc or Capsulectomy, Addressing Autoimmunity, and ... 1:04:59

28d ago1:04:59

1:04:59

In this episode, we speak with Dr. Kayte Susse about overcoming breast implant illness, sharing her personal journey and expertise on the topic. Dr. Kayte dives into the dangers associated with various types of breast implants, shedding light on the concerns surrounding heavy metals and how they may impact the body. She also explains how to determi…

1
TCR-T cells for post-HCT leukemia recurrence; platelets are the predominant source of procoagulant membranes in hemostasis; BR + R maintenance for MCL 18:10

30d ago18:10

18:10

In this week's episode we'll discuss HA-1-targeted T-cell receptor T-cell therapy for recurrent leukemia after hematopoietic stem cell transplantation. Next, we'll learn about how 4D intravital imaging in mice reveals the key role of platelets as a source of procoagulant membranes in hemostasis. Finally, we'll hear about modifications to a common i…

1
Just the Babes: 6 Simple Steps to Upgrade Your Health l How to Biohack Your Health for Less than 2K a Year! 1:13:58

1M ago1:13:58

1:13:58

Join us for an episode filled with practical strategies to enhance your well-being. We cover 6 key areas essential for optimizing health, offering actionable steps to implement into your daily routine. This episode will help you identify your blindspots, determine which labs to run, clean up your environment, build a balanced diet, support your ner…

1
Ep 150 Norovirus: Tip of the poop iceberg 1:19:40

1M ago1:19:40

1:19:40

“Is it gonna be poop or is it gonna be barf?” It’s the question we all fear during a bout of food poisoning when time is of the essence and a decision has to be made before it’s made for us. Often, the germ forcing this question upon us is none other than the dreaded norovirus. First called “winter vomiting disease” for reasons obvious to anyone wh…

1
Outcomes of younger patients with mantle cell lymphoma; M-protein assessment during maintenance therapy in multiple myeloma; in vivo CAR T-cell generation using lentiviral vectors 0:59

1M ago0:59

0:59

In this week's episode we’ll discuss the outcomes of younger patients with mantle cell lymphoma experiencing late relapse; learn more about mass spectrometry-based assessment of M-protein in peripheral blood during maintenance therapy in multiple myeloma and discuss in vivo CAR T-cell generation in non-human primates using lentiviral vectors. Featu…

1
Review Series on Factor XI 44:40

1M ago44:40

44:40

Introduced by Associate Editor Dr. Thomas Ortel, this bonus episode discusses the Review Series on Factor XI, published in volume 143 issue 15 of Blood Journal. Dr. Ortel is joined by contributing authors Owen McCarty, PhD, Gili Kenet, MD, and David Gailani, MD. Review Series Articles: Introduction to a review series on factor XI Biology of factor …

1
Special Episode: Maria Smilios & The Black Angels 1:04:57

1M ago1:04:57

1:04:57

In the pre-antibiotic era, tuberculosis was one of the biggest killers humanity ever faced. The specter of the ‘great white plague’ hung over towns and cities across the world, cities like New York whose population boom in the early 20th century paved the way for this deadly disease to spread throughout crowded tenements. As tuberculosis rates in N…

1
Protective role of neonatal CMV infection in B-ALL; GVHD targets organoid-forming bile duct stem cells; seven-year outcomes for venetoclax-ibrutinib therapy in MCL 16:56

1M ago16:56

16:56

In this week's episode we'll learn how cytomegalovirus infection early in life depletes preleukemic cells in a mouse model of B-cell acute lymphoblastic leukemia. After that we'll discuss new research, where GVHD targets organoid-forming bile duct stem cells in a TGF-beta-dependent manner. Conversely, a TGF-beta inhibitor protects these stem cells …

1
Ep 149 Poison Control Part 2: Call me maybe 59:37

2M ago59:37

59:37

In last week’s episode/love song to poison control centers, we journeyed through the history of these centers, from idea to institution. This week, we pick up where we left off by taking stock of the incredible impact that poison control centers have had on public health and individual lives. We also get a thrilling behind-the-scenes look at the op…

1
The Iron Protocol: Understanding Iron Deficiency Anemia, Iron Overload & Hemochromatosis, and the Lifestyle and Genetic Predispositions that May Be Affecting Your Iron Status with Dr. Christy Sutton 1:12:06

2M ago1:12:06

1:12:06

In this episode, we speak with Dr. Christy Sutton, author of The Iron Curse, to debunk myths and misconceptions about iron. Dr. Sutton dives into the complex relationship between iron and health, discussing the potential dangers of both low and high iron levels and how they can impact overall well-being. We explore the root causes behind iron imbal…

1
Iron, HFE haemochromatosis, and infections; bispecific antibodies improve CAR T-cell response; determinants of outcome in NPM1-mutated AML 23:31

2M ago23:31

23:31

In this week's episode we'll learn about iron, HFE hemochromatosis, and infections. In this large, population-based study, both high and low levels of plasma iron and transferrin saturation were associated with increased risks of infection. Then, we'll discuss how bispecific antibodies improve CAR T-cell response in B-cell malignancies. In-vitro an…

1
Ep 148 Poison Control Part 1: Who you gonna call? 56:16

2M ago56:16

56:16

If you’ve ever called poison control, you probably already have a deep appreciation for the voice on the other end of the line who provides solid answers, emanates calm, and empowers you to take whatever steps necessary to be safe and healthy. If you haven’t, this episode will turn you into a superfan anyway. How did this incredibly valuable yet of…

1
Menopause is Natural, Suffering is Optional l Supporting Women's Health & Optimizing Hormones with The Girlfriend Doctor - Dr. Anna Cabeca 1:05:38

2M ago1:05:38

1:05:38

In this episode, we sit down with Dr. Anna Cabeca, affectionately known as "The Girlfriend Doctor," to explore the natural journey of menopause and how suffering during this phase is entirely optional. She delves into her holistic approach to managing hormones, as well as steps to prepare the female body for pregnancy. She highlights her top lab te…

1
Immune fitness and response to taclistamab in R/R multiple myeloma; BCR::ABL1 M244V mutation causes resistance to asciminib; HSCT and myocardial fibrosis in young patients with SCD 16:59

2M ago16:59

16:59

In this week's episode we’ll discuss how immune fitness impacts response to teclistamab in relapsed/refractory multiple myeloma; learn more about a new mechanism of resistance to asciminib conferred by the BCR::ABL1 M244V mutation, and discuss the impact of hematopoietic cell transplantation on myocardial fibrosis in young patients with sickle cell…

1
Special Episode: Ben Goldfarb & Crossings 1:00:21

2M ago1:00:21

1:00:21

Roads are essential to our modern lives, so much so that they largely exist in the background of our minds. When we do think of roads, we’re either complaining about traffic or celebrating them for enabling our restless need to explore. Can you imagine if all of the world’s 40 million miles of roads were suddenly erased? Chaos for humanity. But a b…

1
Health (and disease) Begins in Your Mouth! A Biological Dentistry to Approach to Amalgam Fillings, Root Canals, Cavitations, Oral Health, EMFs and more with Dr. Dome Nischwitz 1:06:13

2M ago1:06:13

1:06:13

In this episode, we dive into the fascinating world of biological dentistry with Dr. Dominik Nischwitz, one of the globe's leading experts in the field. He sheds light on the stark differences between conventional and biological dentistry, emphasizing the importance of a holistic approach. We explore the significant impact that heavy metals can hav…

1
Decitabine in older patients with AML; EPCR and sickle chronic kidney disease; lymphocyte depletion versus post-transplant cyclophosphamide for mismatched donor transplant for inborn errors of immunity ... 22:53

2M ago22:53

22:53

In this week's episode we’ll discuss the safety and efficacy of decitabine in older patients with AML; learn how heme-induced loss of renovascular endothelial protein C receptor promotes chronic kidney disease in sickle mice, and discuss the outcomes of treatment with HLA-mismatched HSCT with TCRab/CD19 lymphocyte depletion or post-HSCT cyclophosph…

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Hemochromatosis Podcasts

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