The Lancet Neurology is a monthly journal, renowned for the publication of high-quality peer-reviewed research, reviews, and analysis from around the world. In the monthly podcasts, editors of the journal discuss highlights of the current issue, with occasional interviews with an author of a key article.
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The Lancet Neurology in conversation with


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The Lancet Neurology in conversation with
The Lancet Group
Editors of The Lancet Neurology and the journal’s authors explore their research and its impact on people’s health, health care, and health policy in this regular podcast.
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The Lancet (www.thelancet.com) is a weekly medical journal, renowned for the publication of high-quality peer-reviewed research and reviews from around the world. In the Podcasts our editors discuss journal highlights, including interviews with authors of key articles to provide context and insight to advancements in medicine and health worldwide.
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In conversation with... Anthony Feinstein
14:42
14:42
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Anthony Feinstein (University of Toronto and Sunnybrook Health Sciences Centre, Toronto, Canada) discusses CogEx, a randomised trial of cognitive rehabilitation and aerobic exercise for cognitive impairment in people with progressive multiple sclerosis. The Article is published in the October issue of The Lancet Neurology.…
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The Lancet Neurology in conversation with


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Anthony Feinstein on a trial of cognitive rehabilitation and exercise in people with progressive multiple sclerosis
14:42
14:42
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Anthony Feinstein (University of Toronto and Sunnybrook Health Sciences Centre, Toronto, Canada) discusses CogEx, a randomised trial of cognitive rehabilitation and aerobic exercise for cognitive impairment in people with progressive multiple sclerosis. The Article is published in the October issue of The Lancet Neurology. Continue this conversatio…
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Simon Kyle joins Gavin Cleaver of The Lancet to discuss his paper on sleep restriction therapy as a new effective treatment for insomnia.By The Lancet
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William Jagust (University of California in Berkeley, CA, USA) talks to Senior Editor Sarah Passey about the complex pathway between amyloid β and cognition, and implications for therapy for people with Alzheimer’s disease. His Personal View on this topic is published in the September issue of The Lancet Neurology.…
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William Jagust on amyloid β and cognition
13:36
13:36
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William Jagust (University of California in Berkeley, CA, USA) talks to Senior Editor Sarah Passey about the complex pathway between amyloid β and cognition, and implications for therapy for people with Alzheimer’s disease. His Personal View on this topic is published in the September issue of The Lancet Neurology. Read the full article: https://ww…
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In conversation with... Stephen Strittmatter
14:34
14:34
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Stephen Strittmatter (Yale School of Medicine, CT, USA) discusses his first-in-human and randomised trial of a soluble Nogo-receptor-Fc decoy in patients with chronic cervical spinal cord injury. The Article is published in the August issue of The Lancet Neurology.By The Lancet
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The Lancet Neurology in conversation with


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Stephen Strittmatter on a first-in-human trial for treating chronic cervical spinal cord injury
14:34
14:34
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Stephen Strittmatter (Yale School of Medicine, CT, USA) discusses his first-in-human and randomised trial of a soluble Nogo-receptor-Fc decoy in patients with chronic cervical spinal cord injury. The Article is published in the August issue of The Lancet Neurology. Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-44…
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In conversation with... Benzi Kluger, Claire Creutzfeldt, and Malenna Sumrall
17:20
17:20
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Benzi Kluger (University of Rochester Medical Center, Rochester, NY, USA), Claire Creutzfeldt (University of Washington, Seattle, WA, USA), and Malenna Sumrall (University of Colorado Anschutz Medical Campus, Aurora, CO, USA) join Jonathan Blott to discuss palliative care for individuals with neurological diseases, exploring the challenges and oppo…
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The Lancet Neurology in conversation with


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Benzi Kluger, Claire Creutzfeldt, and Malenna Sumrall on palliative care for individuals with neurological diseases
17:20
17:20
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Benzi Kluger (University of Rochester Medical Center, Rochester, NY, USA), Claire Creutzfeldt (University of Washington, Seattle, WA, USA), and Malenna Sumrall (University of Colorado Anschutz Medical Campus, Aurora, CO, USA) join Jonathan Blott to discuss palliative care for individuals with neurological diseases, exploring the challenges and oppo…
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Andrew Cole (Massachusetts General Hospital Epilepsy Service, Boston, MA, USA) talks to Senior Editor Sarah Passey about the complexities underlying epilepsy in people with glioblastoma. His Review on this topic is published in the June issue of The Lancet Neurology.By The Lancet
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Andrew Cole on the complexities underlying epilepsy in people with glioblastoma
18:38
18:38
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Andrew Cole (Massachusetts General Hospital Epilepsy Service, Boston, MA, USA) talks to Senior Editor Sarah Passey about the complexities underlying epilepsy in people with glioblastoma. His Review on this topic is published in the June issue of The Lancet Neurology. Read the full article here: thelancet.com/journals/laneur/article/PIIS1474-4422(23…
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In conversation with... Karen Duff and Connor Langworth-Green
15:20
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Karen Duff and Connor Langworth-Green (University College London, London, UK) discuss tauopathies and the chronic effects of inflammation on this group of disorders. Their Personal View on this topic is published in the May issue of The Lancet Neurology.By The Lancet
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Karen Duff and Connor Langworth-Green on tauopathies and chronic inflammation
15:20
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Karen Duff and Connor Langworth-Green (University College London, London, UK) discuss tauopathies and the chronic effects of inflammation on this group of disorders. Their Personal View on this topic is published in the May issue of The Lancet Neurology. Read the Personal View here: Chronic effects of inflammation on tauopathies Continue this conve…
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Kerstin Hellwig on family planning considerations in MS
14:24
14:24
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Kerstin Hellwig (Ruhr University Bochum, Bochum, Germany) discusses family planning considerations in multiple sclerosis. This Review is published in the April issue of The Lancet Neurology. Continue this conversation on social! Follow us today at... https://twitter.com/thelancet https://instagram.com/thelancetgroup https://facebook.com/thelancetme…
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Kerstin Hellwig (Ruhr University Bochum, Bochum, Germany) discusses family planning considerations in multiple sclerosis. This Review is published in the April issue of The Lancet Neurology.By The Lancet
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Geraldine Dawson on advances in the prediction of autism during infancy
24:34
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Geraldine Dawson (Duke University School of Medicine, NC, USA ) discusses the latest advances and ongoing challenges in prediction of autism during infancy. This Review is published in the March issue of The Lancet Neurology. Read the full article: Prediction of autism in infants: progress and challenges Continue this conversation on social! Follow…
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Geraldine Dawson (Duke University School of Medicine, NC, USA) discusses the latest advances and ongoing challenges in prediction of autism during infancy. This Review is published in the March issue of The Lancet Neurology.By The Lancet
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Ellisiv Mathiesen (The University of Tromsø – the Arctic University of Norway, Tromsø, Norway) discusses the findings of the TWIST trial, which investigated the use of tenecteplase for patients with wake-up stroke who were selected for treatment by non-contrast CT. This Fast-track Article is published in the February issue of The Lancet Neurology.…
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Ellisiv Mathiesen on tenecteplase for patients with wake-up stroke
8:45
8:45
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Ellisiv Mathiesen (The University of Tromsø – the Arctic University of Norway, Tromsø, Norway) discusses the findings of the TWIST trial, which investigated the use of tenecteplase for patients with wake-up stroke who were selected for treatment by non-contrast CT. This Fast-track Article is published in the February issue of The Lancet Neurology. …
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Editor-in-chief of The Lancet Richard Horton looks back at two centuries of medical publishing, previews how we will be marking the journal’s 200th anniversary, and explains what the milestone means to him.By The Lancet
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Beau Ances (Washington University in St Louis, MO, USA) discusses recent research on amyloid biomarkers in people with genetic forms of Alzheimer’s disease; his Article is published in the January issue of The Lancet Neurology.By The Lancet
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Beau Ances on amyloid biomarkers in Alzheimer’s
11:34
11:34
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11:34
Beau Ances (Washington University in St Louis, MO, USA) discusses recent research on amyloid biomarkers in people with genetic forms of Alzheimer’s disease; his Article is published in the January issue of The Lancet Neurology. Read the full article: Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer'…
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Axel Petzold on the diagnosis and classification of optic neuritis
20:03
20:03
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Axel Petzold (National Hospital for Neurology and Neurosurgery and Moorfields Eye Hospital, London, UK, and Amsterdam University Medical Center, Amsterdam, Netherlands) discusses a Position Paper, published in the December issue of The Lancet Neurology, which sets out new criteria for the diagnosis and classification of optic neuritis. Read the Pos…
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Axel Petzold (National Hospital for Neurology and Neurosurgery and Moorfields Eye Hospital, London, UK, and Amsterdam University Medical Center, Amsterdam, Netherlands) discusses a Position Paper, published in the December issue of The Lancet Neurology, which sets out new criteria for the diagnosis and classification of optic neuritis.…
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Maeike Zijlmans on using biomarkers to tailor epilepsy surgery
14:37
14:37
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14:37
Maeike Zijlmans (University Medical Center Utrecht, Utrecht, Netherlands) discusses recent research on tailoring of epilepsy surgery with biomarkers on intraoperative electrocorticography, and describes some of the challenges of this technique and what the future steps are for the field; the Article is published in the November issue of The Lancet …
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Maeike Zijlmans (University Medical Center Utrecht, Utrecht, Netherlands) discusses recent research on tailoring of epilepsy surgery with biomarkers on intraoperative electrocorticography, and describes some of the challenges of this technique and what the future steps are for the field.By The Lancet
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Anthony Fauci on COVID-19, scientific communication, and the future
29:50
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Dr. Anthony Fauci, Chief Medical Advisor to the President of the United States and Director of NIAID, is standing down at the end of 2022. He joins Gavin and Jessamy to discuss becoming a household name during the COVID-19 pandemic, why scientific discourse in the USA is broken, and how the pandemic could end.…
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Jerome Siegel (University of California, Los Angeles, CA, USA) discusses sleep research in hunter-gatherer populations and what we can learn from the sleep habits of various species; his Review is published in the October issue of The Lancet Neurology, which is the fourth paper in The Lancet’s Series on sleep and sleep disorders.…
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Jerome Siegel (University of California, Los Angeles, CA, USA) discusses sleep research in hunter-gatherer populations and what we can learn from the sleep habits of various species; his Review is published in the October issue of The Lancet Neurology, which is the fourth paper in The Lancet’s Series on sleep and sleep disorders. Continue this conv…
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Laurent Servais and Dora Markati (both from the University of Oxford, UK) discuss emerging therapies for Duchenne muscular dystrophy; their Review is published in the September issue of The Lancet Neurology.By The Lancet
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Laurent Servais and Dora Markati on emerging therapies for Duchenne muscular dystrophy
17:13
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Laurent Servais and Dora Markati (both from the University of Oxford, UK) discuss emerging therapies for Duchenne muscular dystrophy; their Review is published in the September issue of The Lancet Neurology. Read the full Review: Emerging therapies for Duchenne muscular dystrophy Continue this conversation on social! Follow us today at... https://t…
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In conversation with... Andreas Charidimou
22:58
22:58
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Andreas Charidimou (Massachusetts General Hospital, Boston, MA, USA) discusses an international collaborative study that presents new Boston criteria for diagnosis of cerebral amyloid angiopathy; the Article is published in the August issue of The Lancet Neurology.By The Lancet
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Andreas Charidimou on new criteria for diagnosis of cerebral amyloid angiopathy
22:58
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Andreas Charidimou (Massachusetts General Hospital, Boston, MA, USA) discusses an international collaborative study that presents new Boston criteria for diagnosis of cerebral amyloid angiopathy; the Article is published in the August issue of The Lancet Neurology. Read the full article: The Boston criteria version 2.0 for cerebral amyloid angiopat…
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In conversation with... Sarah Tabrizi and Cristina Sampaio
18:52
18:52
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Sarah Tabrizi (UCL Queen Square Institute of Neurology, London, UK) and Cristina Sampaio (CHDI Foundation, Princeton, NJ, USA) discuss two papers on Huntington’s disease published in the July issue of The Lancet Neurology: a Position Paper outlining a new classification of the disease, called the Huntington’s Disease Integrated Staging System, and …
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Sarah Tabrizi and Cristina Sampaio on classifying Huntington's and new therapies
18:52
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Sarah Tabrizi (UCL Queen Square Institute of Neurology, London, UK) and Cristina Sampaio (CHDI Foundation, Princeton, NJ, USA) discuss two papers on Huntington’s disease published in the July issue of The Lancet Neurology: a Position Paper outlining a new classification of the disease, called the Huntington’s Disease Integrated Staging System, and …
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How does health shape politics? How does politics shape health? Why do some diseases get international attention and funding when others don’t? What role do institutions play? Richard Horton, Eduardo Gomez, and Jeremy Shiffman join Jessamy and Gavin to discuss the talking points from a new Lancet Series on Political Science and Health.…
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Mark Hallett on functional neurological disorder
8:43
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Mark Hallett (National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA) discusses his Review, published in the June issue of The Lancet Neurology, on functional neurological disorder, and talks about new subtypes of this disorder, diagnostic challenges, and how education is important. Read the full article: Functional neurological…
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Mark Hallett (National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA) discusses his Review, published in the June issue of The Lancet Neurology, on functional neurological disorder, and talks about new subtypes of this disorder, diagnostic challenges, and how education is important.…
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The past and future of child health, with Richard Horton
17:59
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In 2019 there were 8.6m deaths globally among children and adolescents aged 0-20 years. Almost two decades on from The Lancet’s first ever global health series, on child survival, we've published our new Series, Optimising Child and Adolescent Health and Development. Richard Horton reflects on the progress and setbacks across 20 years of child heal…
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Eva Feldman (University of Michigan, Ann Arbor, USA) discusses the latest advances in the genetics, risk factors, pathophysiology, therapeutic development, and the diagnosis and prognosis of amyotrophic lateral sclerosis; the Series is published in the May issue of The Lancet Neurology.By The Lancet
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Eva Feldman on advances in understanding ALS
22:43
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Eva Feldman (University of Michigan, Ann Arbor, USA) discusses the latest advances in the genetics, risk factors, pathophysiology, therapeutic development, and the diagnosis and prognosis of amyotrophic lateral sclerosis; the Series is published in the May issue of The Lancet Neurology. Continue this conversation on social! Follow us today at... ht…
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In conversation with... Estrella Morenas-Rodriguez and Christian Haass
27:15
27:15
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Estrella Morenas-Rodriguez and Christian Haass (German Centre for Neurodegenerative Diseases, Munich, Germany) discuss their recent research, published in the April issue of The Lancet Neurology, on soluble TREM2 and its association with Alzheimer’s disease biomarkers and cognition.By The Lancet
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Estrella Morenas-Rodriguez and Christian Haass on soluble TREM2 and Alzheimer's
27:15
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Estrella Morenas-Rodriguez and Christian Haass (German Centre for Neurodegenerative Diseases, Munich, Germany) discuss their recent research, published in the April issue of The Lancet Neurology, on soluble TREM2 and its association with Alzheimer’s disease biomarkers and cognition. Continue this conversation on social! Follow us today at... https:…
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John Collinge (MRC Prion Unit, University College London, London, UK) discusses a first-in-human treatment programme to give PRN100, an anti-prion-protein monoclonal antibody, to patients with Creutzfeldt–Jakob disease; the report is published in the April issue of The Lancet Neurology.By The Lancet
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John Collinge (MRC Prion Unit, University College London, London, UK) discusses a first-in-human treatment programme to give PRN100, an anti-prion-protein monoclonal antibody, to patients with Creutzfeldt–Jakob disease; the report is published in the April issue of The Lancet Neurology. Continue this conversation on social! Follow us today at... ht…
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The past, present, and future of health in Nigeria
34:40
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Ibrahim Abubakar, Tolullah Oni, and Obinna Onwujekwe join The Lancet Voice to discuss how Nigeria's history affects the modern-day health system, and the challenges and opportunities for Nigeria in the future.By The Lancet
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In conversation with... Verna Vanderpuye and Isabelle Soerjomataram
12:56
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On this International Women's Day, Lancet editors and the co-chairs of the Women and Cancer Commission discuss the burden of women’s cancer on society and reflect on the questions the Commission is trying to answer.By The Lancet
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Inequity, society, and infectious diseases in the USA
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Professor Samuel K. Roberts joins Gavin and Jessamy to discuss racial inequities in the USA and how infectious diseases historically find and exploit the gaps in societies.By The Lancet
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Alexandra Durr on riluzole in patients with spinocerebellar ataxia type 2
7:55
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Alexandra Durr (Paris Brain Institute, Pitié-Salpêtrière Paris, France) discusses the ATRIL study, a randomised trial of riluzole in patients with spinocerebellar ataxia type 2, which is published in the March issue of The Lancet Neurology. Read the full article: Safety and efficacy of riluzole in spinocerebellar ataxia type 2 in France (ATRIL) Con…
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Alexandra Durr (Paris Brain Institute, Pitié-Salpêtrière Paris, France) discusses the ATRIL study, a randomised trial of riluzole in patients with spinocerebellar ataxia type 2, which is published in the March issue of The Lancet Neurology.By The Lancet
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