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Empowered Patient Podcast with Karen Jagoda is a window into the latest innovations in digital health, the changing dynamic between doctors and patients, and the emergence of precision medicine. The show covers such topics as aging in place, innovative uses for wearables and sensors, advances in clinical research, applied genetics, drug development, and challenges for connected health entrepreneurs.
 
A geriatrics and palliative care podcast for every health care professional. We invite the brightest minds in geriatrics, hospice, and palliative care to talk about the topics that you care most about, ranging from recently published research in the field to controversies that keep us up at night. You'll laugh, learn and maybe sing along. Hosted by Eric Widera and Alex Smith.
 
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show series
 
Welcome to season three of the Beyond Celiac podcast, Celiac Straight Talk! We're excited to bring you more stories, research, and news about celiac disease. Our first guest is Jessica Kapusta, an entrepreneur who's putting her experience with celiac disease to good use by developing delicious gluten-free sauces. COVID-19 put a hold on manufacturin…
 
There are no currently approved disease modifying drugs for Alzheimer's disease, but in a couple months that may change. In July of 2021, the FDA will consider approval of a human monoclonal antibody called Aducanumab for the treatment of Alzheimer's disease. If approved, it will not only make this drug the defacto standard of care for Alzhimers di…
 
Luke Smith, Client Operations Analyst, Central Logic and the Director of the Arizona Surge Line finally has time to reflect on the work that went into managing access to hospitals and post-acute care for patients suffering from COVID-10 throughout the state of Arizona, at one point the number 1 hot spot in the world for positivity. The Surge Line A…
 
Luke Smith, Client Operations Analyst, Central Logic and the Director of the Arizona Surge Line finally has time to reflect on the work that went into managing access to hospitals and post-acute care for patients suffering from COVID-10 throughout the state of Arizona, at one point the number 1 hot spot in the world for positivity. The Surge Line A…
 
Amy Grover, Director of Patient Advocacy, Catalyst Pharmaceuticals works primarily with patients suffering from Lambert-Eaton Myasthenic Syndrome LEMS an ultra-rare disease which is very similar to a larger rare disease myasthenia gravis MG. Working with the patient community and patient advocacy groups, Catalyst is providing support, tools and res…
 
Amy Grover, Director of Patient Advocacy, Catalyst Pharmaceuticals works primarily with patients suffering from Lambert-Eaton Myasthenic Syndrome LEMS an ultra-rare disease which is very similar to a larger rare disease myasthenia gravis MG. Working with the patient community and patient advocacy groups, Catalyst is providing support, tools and res…
 
Sally Embrey, Vice President Public Health and Health Tech, DataRobot is applying knowledge from work as an enterprise AI company to attacking the problem of containing and defeating COVID-19. ContagionNET was created to identify leading and lagging indicators of the next COVID-19 hotspot and to help people understand their status, risk and ability…
 
Sally Embrey, Vice President Public Health and Health Tech, DataRobot is applying knowledge from work as an enterprise AI company to attacking the problem of containing and defeating COVID-19. ContagionNET was created to identify leading and lagging indicators of the next COVID-19 hotspot and to help people understand their status, risk and ability…
 
One of our earliest COVID podcasts with Jim Wright and David Grabowski a year ago addressed the early devastating impact of COVID on nursing homes. One year ago Mike Wasserman, geriatrician and immediate past president of the California Long Term Care Association, said we’d have a quarter million deaths in long term care. A quarter of a million dea…
 
Dr. Stephen Brannan, Chief Medical Officer, Karuna Therapeutics discusses the need for creating and delivering transformative medicines for people living with psychiatric and neurological conditions particularly schizophrenia. Pairing the muscarinic agonist with a pan-cholinergic antagonist that does not cross into the central nervous system, KarXT…
 
Dr. Stephen Brannan, Chief Medical Officer, Karuna Therapeutics discusses the need for creating and delivering transformative medicines for people living with psychiatric and neurological conditions particularly schizophrenia. Pairing the muscarinic agonist with a pan-cholinergic antagonist that does not cross into the central nervous system, KarXT…
 
Jonathan Rigby, CEO, Revolo Biotherapeutics discusses the company's revolutionary therapies powered to reset the immune system to achieve superior long-term remission for patients with autoimmune and allergic diseases, with less frequent chronic dosing and without suppression of the immune system. A goal that others have not been able to reach. Rev…
 
Jonathan Rigby, CEO, Revolo Biotherapeutics discusses the company's revolutionary therapies powered to reset the immune system to achieve superior long-term remission for patients with autoimmune and allergic diseases, with less frequent chronic dosing and without suppression of the immune system. A goal that others have not been able to reach. Rev…
 
Anthony Comfort, VP Product Management, VisiQuate reflects on how far science and technology have come in helping monitor the health of diabetics with a new understanding of chemical changes in the body as well as cognitive and behavioral aspects. With the change from manual monitoring blood glucose readings to continuous data streaming in real tim…
 
Anthony Comfort, VP Product Management, VisiQuate reflects on how far science and technology have come in helping monitor the health of diabetics with a new understanding of chemical changes in the body as well as cognitive and behavioral aspects. With the change from manual monitoring blood glucose readings to continuous data streaming in real tim…
 
Derek Maetzold, President and CEO, Castle Biosciences is harnessing the power of genomics to understand the biology of skin cancer. Castle has developed genomic tests to determine how aggressive melanoma and squamous cell carcinoma are in order to better inform dermatologist and patients about intervention decisions. With both diagnostic and progno…
 
Derek Maetzold, President and CEO, Castle Biosciences is harnessing the power of genomics to understand the biology of skin cancer. Castle has developed genomic tests to determine how aggressive melanoma and squamous cell carcinoma are in order to better inform dermatologist and patients about intervention decisions. With both diagnostic and progno…
 
Len May, CEO, EndoCanna Health is aggressively exploring the genes that are associated with metabolism of cannabinoids and aiming for a better understanding of the endocannabinoid system to guide the use of cannabis for a wide range of conditions and disorders. With an eye to the complexity of the cannabis plant, EndoCanna has developed a test to d…
 
Len May, CEO, EndoCanna Health is aggressively exploring the genes that are associated with metabolism of cannabinoids and aiming for a better understanding of the endocannabinoid system to guide the use of cannabis for a wide range of conditions and disorders. With an eye to the complexity of the cannabis plant, EndoCanna has developed a test to d…
 
Evan Levine, Co-Founder and CEO, PsyBio Therapeutics is pursuing a paradigm shift in the treatment of mental illness and other neurological disorders by using psychedelics and hallucinogenics. PsyBio biosynthesizes psilocybin and other psychoactive drugs from different plants and fungi from genetically-modified bacteria. Under the influence of an a…
 
Evan Levine, Co-Founder and CEO, PsyBio Therapeutics is pursuing a paradigm shift in the treatment of mental illness and other neurological disorders by using psychedelics and hallucinogenics. PsyBio biosynthesizes psilocybin and other psychoactive drugs from different plants and fungi from genetically-modified bacteria. Under the influence of an a…
 
Michael Tkach, Chief Operating Officer and Chief Behavioral Health Officer, Affinity describes a variety of models for large-scale population healthcare management for Return to Work/Stay at Work in this time of COVID-19. With continuous monitoring, testing and data analysis, risk assessment is being used to keep companies aware of adherence to gui…
 
Michael Tkach, Chief Operating Officer and Chief Behavioral Health Officer, Affinity describes a variety of models for large-scale population healthcare management for Return to Work/Stay at Work in this time of COVID-19. With continuous monitoring, testing and data analysis, risk assessment is being used to keep companies aware of adherence to gui…
 
Dr. Greg Rippon, Vice President and Chief Medical Partner of Neurology, Genentech shines light on SMA, spinal muscular atrophy, a severe inherited progressive neuromuscular disease and one of the most common rare diseases affecting babies. With the introduction of Evrysdi to the treatment options for SMA, an oral treatment is being tested to increa…
 
Dr. Greg Rippon, Vice President and Chief Medical Partner of Neurology, Genentech shines light on SMA, spinal muscular atrophy, a severe inherited progressive neuromuscular disease and one of the most common rare diseases affecting babies. With the introduction of Evrysdi to the treatment options for SMA, an oral treatment is being tested to increa…
 
COVID has taken a devastated toll in nursing homes. Despite representing fewer than 5% of the total US events, at least 40% of COVID‐19–related deaths occurred in older individuals living in nursing homes. The good news is that with the introduction of COVID vaccines in nursing homes, numbers of infections and outbreaks have plummeted. However, onl…
 
Dr. Sudarshan Hebbar, Chief Medical Officer, CalciMedica talks about developing drugs that are focused on targeting CRAC channels, calcium release activated calcium channels, in order to modulate these channels to help treat diseases that have a significant inflammatory component. Initially developed drugs for acute pancreatitis targeting both the …
 
Dr. Sudarshan Hebbar, Chief Medical Officer, CalciMedica talks about developing drugs that are focused on targeting CRAC channels, calcium release activated calcium channels, in order to modulate these channels to help treat diseases that have a significant inflammatory component. Initially developed drugs for acute pancreatitis targeting both the …
 
Dr. Aaron Koenig, Senior Medical Director and Mike Quirk, Vice President of pharmacology Sage Therapeutics focus on disorders of cognition and diseases that reflect determinants of impaired cognition such as Alzheimer's, Parkinson's and Huntington's. Their drug Sage-718, a novel mechanism of action, targets a protein in the brain, the NMDA receptor…
 
Dr. Aaron Koenig, Senior Medical Director and Mike Quirk, Vice President of pharmacology Sage Therapeutics focus on disorders of cognition and diseases that reflect determinants of impaired cognition such as Alzheimer's, Parkinson's and Huntington's. Their drug Sage-718, a novel mechanism of action, targets a protein in the brain, the NMDA receptor…
 
Dr. Travis Mickle President and CEO KemPharm describes the development of AZSTARYS, the stimulant-based methylphenidate prodrug treatment for ADHD one of the most common central nervous system diseases. This prodrug stimulates the norepinephrine dopamine reuptake inhibitor improving concentration, executive function, and irritability and provides f…
 
Dr. Travis Mickle President and CEO KemPharm describes the development of AZSTARYS, the stimulant-based methylphenidate prodrug treatment for ADHD one of the most common central nervous system diseases. This prodrug stimulates the norepinephrine dopamine reuptake inhibitor improving concentration, executive function, and irritability and provides f…
 
Hospice may not be a great match for all of the care needs of people with dementia, but it sure does help. And, as often happens, when patients with dementia do not decline as expected, they are too frequently discharged from hospice, an experience that Lauren Hunt and Krista Harrison refer to in an editorial in the Journal of the American Geriatri…
 
Dr. Mark Allen, Co-Founder and CEO, Elevian is looking to disrupt the longevity business by developing a recombinant GDF11 to treat and prevent multiple age-related diseases. The first application being investigated is for stroke recovery drawing on the discovery that GDF11 decreases with age and when replenished, returns the brain to a healthier p…
 
Dr. Mark Allen, Co-Founder and CEO, Elevian is looking to disrupt the longevity business by developing a recombinant GDF11 to treat and prevent multiple age-related diseases. The first application being investigated is for stroke recovery drawing on the discovery that GDF11 decreases with age and when replenished, returns the brain to a healthier p…
 
Dr. Steve Kanes, Chief Medical Officer, Sage Therapeutics takes the view that mental disorders and brain health disorders need to be treated like any other medicine. Driving this paradigm shift is the development of breakthrough zuranalone, an oral limited-time treatment to replace taking medicine chronically for those suffering from major depressi…
 
Dr. Steve Kanes, Chief Medical Officer, Sage Therapeutics takes the view that mental disorders and brain health disorders need to be treated like any other medicine. Driving this paradigm shift is the development of breakthrough zuranalone, an oral limited-time treatment to replace taking medicine chronically for those suffering from major depressi…
 
Louis Martinez, Chief Information Officer, EHR Data shines a light on the decentralization of healthcare data collected by providers, insurance carriers, pharmacists and other medical service providers. With a goal of centralizing disparate health data and providing access at point of care, EHR is using blockchain to collect data globally to allow …
 
Louis Martinez, Chief Information Officer, EHR Data shines a light on the decentralization of healthcare data collected by providers, insurance carriers, pharmacists and other medical service providers. With a goal of centralizing disparate health data and providing access at point of care, EHR is using blockchain to collect data globally to allow …
 
Vu Truong, CEO, Aridis Pharmaceuticals is taking on the challenge of making an inhaled monoclonal antibody to treat COVID-19 to allow for the easier patient access. Drawing on their work in infectious diseases and with a number of monoclonal antibodies candidates to treat bacteria infection associated with superbugs and antibiotic resistance, Aridi…
 
Vu Truong, CEO, Aridis Pharmaceuticals is taking on the challenge of making an inhaled monoclonal antibody to treat COVID-19 to allow for the easier patient access. Drawing on their work in infectious diseases and with a number of monoclonal antibodies candidates to treat bacteria infection associated with superbugs and antibiotic resistance, Aridi…
 
Niloy Sanyal, Chief Marketing Officer, LeanTaaS is focused on the current state of the healthcare system in this wartime environment. In light of COVID-19 challenges particularly for those patients needing acute care, the need to optimize use of operating rooms, ICU beds, infusion chairs, and medical professionals requires more attention to improvi…
 
Niloy Sanyal, Chief Marketing Officer, LeanTaaS is focused on the current state of the healthcare system in this wartime environment. In light of COVID-19 challenges particularly for those patients needing acute care, the need to optimize use of operating rooms, ICU beds, infusion chairs, and medical professionals requires more attention to improvi…
 
Mariya Pylypiv, Founder and Co-Chairwoman, UpHealth talks about empowering patients suffering from chronic conditions with a global comprehensive digital health technology and tech-enabled services platform. Working with care providers, health systems and payers, UpHealth is addressing the complex medical, behavioral, and social challenges of this …
 
Mariya Pylypiv, Founder and Co-Chairwoman, UpHealth talks about empowering patients suffering from chronic conditions with a global comprehensive digital health technology and tech-enabled services platform. Working with care providers, health systems and payers, UpHealth is addressing the complex medical, behavioral, and social challenges of this …
 
The COVID pandemic brought to light many things, including how society views older adults. Louise Aronson wrote a piece in the NY Times titled “‘Covid-19 Kills Only Old People.’ Only? Why are we OK with old people dying?”. The ageist viewpoint she was rallying against was also brought to light in a study of ageism in social media. When looking at t…
 
Lynne Georgopoulos, VP Regulatory Strategy, Certara describes the company's platform to optimize pediatric drug development using biosimulation. With an eye on pediatric diseases, Certara is employing modeling and simulation to determine how a drug developed for adults may be metabolized in children, including neonates. They are also operationalizi…
 
Lynne Georgopoulos, VP Regulatory Strategy, Certara describes the company's platform to optimize pediatric drug development using biosimulation. With an eye on pediatric diseases, Certara is employing modeling and simulation to determine how a drug developed for adults may be metabolized in children, including neonates. They are also operationalizi…
 
Dr. Romina Ghassemi, chiropractor and founder of Think Healthy is an expert on posture and is raising awareness about the need to address the health of the full spine along with solutions to address stress and related diseases. Her traditional business has been with the aging population to reduce pain and insure mobility. COVID-19 has increased the…
 
Dr. Romina Ghassemi, chiropractor and founder of Think Healthy is an expert on posture and is raising awareness about the need to address the health of the full spine along with solutions to address stress and related diseases. Her traditional business has been with the aging population to reduce pain and insure mobility. COVID-19 has increased the…
 
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