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A strategic podcast where Amy Ledin talks about the main F’s that have influenced her life and have helped her in creating her best self. She covers areas in faith, family, forgiveness, food, fitness, and formula. She will deep dive into how placing her baby for adoption at 18, losing almost 100 pounds, facing her marriage-ending affair, and battling stage 4 cancer for almost 7 years, has only made her stronger. Join Amy as she takes you through her story, her life-changing struggles, and sh ...
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Listen to podcasts with key opinion leaders in multiple therapy areas, discussing hot topics including topic overviews, expert opinions and conference overviews. Brought to you by the Adis Journals Group, part of Springer Nature. The primary audience for these podcasts are healthcare professionals, and are published and citable through the journals.
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Oncotarget

Oncotarget Podcast

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Oncotarget is a primarily oncology-focused, peer-reviewed, open access journal. Papers are published continuously within yearly volumes in their final and complete form and then quickly released to Pubmed. Oncotarget is now indexed by MEDLINE, PubMed and PMC/PubMed. Read about the Oncotarget Scientific Integrity Process: https://www.oncotarget.com/scientific_integrity/
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Mastering Meal Planning: Insights for Sustainable Nutrition Dive into the world of strategic meal planning with Amy Ledin as she unveils key insights for success. Explore practical strategies, meal ideas, and mindful eating tips designed to revolutionize your approach to nutrition. From managing cravings to optimizing meal timing, discover the secr…
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BUFFALO, NY- April 29, 2024 – Oncotarget is a contributing #sponsor at the 19th International p53 Workshop, organized by the International Center for Genetic Engineering and Biotechnology (ICGEB), which takes place from May 13–16, 2024, in Trieste, Italy.“Groundbreaking research and cutting-edge advancements in the field of the most studied human g…
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In this podcast, the Chair and Secretary of the 2023 International Working Group on the Diabetic Foot (IWGDF) guideline on prevention for diabetes-related foot ulcers. This podcast aims to highlight the importance of ulcer prevention and the opportunities to incorporate recommendations into clinical practice. This podcast is published open access i…
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Anaplastic large cell lymphoma (ALCL) and inflammatory myofibroblastic tumor (IMT) are rare cancers observed predominantly in children and young adults. ALCL accounts for 10–15% of all pediatric non-Hodgkin lymphomas and is commonly diagnosed at an advanced stage of disease. This podcast provides an overview of ALK-positive ALCL and IMT. The author…
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In this podcast, the authors reviewed and discussed seven abstracts presented at the 65th Annual Meeting of the American Society of Hematology, focusing on B cell maturation antigen-directed therapies, emphasizing the value of real-world data (RWD) in treatment decision-making, and suggesting how RWD can help advance multiple myeloma research. Thes…
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Chimeric antigen receptor T cell (CAR-T) therapies targeting the CD19 antigen have been associated with high and durable response rates in patients with diffuse large B cell lymphoma (DLBCL). In this podcast, Dr. Foley and Dr. Kuruvilla discuss the case of a patient presenting with the ideal profile for CAR-T cell therapy referral whilst also deter…
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In this enlightening episode, Amy Ledin welcomes back Isaac Ho for a deep dive into understanding the intricate relationship between our emotions, physical health, and overall well-being. Isaac, with 20 years of experience as a trainer and therapist, shares his journey and insights into how our bodies respond to stress and the significance of tunin…
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BUFFALO, NY- April 16, 2024 – A new #researchpaper was #published in Oncotarget's Volume 15 on April 12, 2024, entitled, “Novel therapeutic bispecific antibodies for B-cell lymphoma targeting IgM and other antigens on the B-cell surface.”The B-cell receptor regulates B-cell proliferation and apoptosis. Aberrations in BCR signaling are associated wi…
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Host Amy Ledin delves into the transformative power of emotional maturity with Dr. Nicole LePera, the Holistic Psychologist. This insightful episode explores the impact of childhood experiences, the significance of self-care in managing triggers, the effectiveness of future self-journaling for rewiring habits, and the profound benefits of community…
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Acute myeloid leukemia (AML) is a cancer characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells. ABT199, also known as venetoclax, is a targeted therapy that inhibits the BCL-2 protein, which is often overexpressed in AML cells and contributes to the…
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BUFFALO, NY- April 10, 2024 – A new #researchpaper was #published in Oncotarget's Volume 15 on April 8, 2024, entitled, “Exploring the role of GHRH antagonist MIA-602 in overcoming Doxorubicin-resistance in acute myeloid leukemia.”Acute myeloid leukemia (AML) is characterized by the rapid proliferation of mutagenic hematopoietic progenitors in the …
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Panel-based sequencing platforms are becoming more accessible, and molecular biomarker analysis of circulating tumor DNA is becoming more common. In this podcast, authors discuss the importance of biomarker testing in advanced non-small cell lung cancer (NSCLC) and explore topics such as testing methodologies, effect of biomarker testing on patient…
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Cancer therapy has come a long way from its one-size-fits-all beginning to the awakening era of personalized medicine. This change has been largely driven by the discovery of biomarkers. Biomarkers can help refine patient selection for specific therapies. A blend of causal and correlative approaches is needed to elucidate the full potential of biom…
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BUFFALO, NY- March 27, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on March 19, 2024, entitled, “Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stage II–III breast cancer.”In this new study, researchers Haven R. Garber, Sreyashi Basu, Sonali Jindal, Zhong He, Khoi Chu, …
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BUFFALO, NY- March 25, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on March 14, 2024, entitled, “ABT199/venetoclax synergism with thiotepa enhances the cytotoxicity of fludarabine, cladribine and busulfan in AML cells.”ABT199/venetoclax, an inhibitor of the pro-survival BCL-2 protein, has improved AML treatment. Its effica…
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In this podcast the Chair and Secretary of the 2023 International Working Group on the Diabetic Foot (IWGDF) guideline on offloading treatments for diabetes-related foot ulcers briefly discuss why we need offloading treatments for people with diabetes-related foot ulcers, what the new international offloading guideline recommends, and where offload…
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Explore the journey of self-recovery with Amy Ledin in 'The Slow Identity Killer,' where she tackles the challenges of losing one's sense of self through life's unpredictability's. She reveals her personal struggle through a season of upheaval, including a significant loss—leading to a disruption of routine and confidence. Discover Amy's raw insigh…
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In this podcast, the Chair and Secretary of the 2023 update of the International Working Group of the Diabetic Foot (IWGDF) guidelines on Classification discuss the results of update to the guidelines addressing the use of systems to classify foot ulcers in people with diabetes in routine clinical practice. This podcast is published open access in …
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Patients with metastatic epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC) are widely treated with osimertinib, the preferred first-line treatment option. However, disease progression inevitably occurs, driven by EGFR-dependent or EGFR-independent mechanisms of resistance. Platinum-based chemotherapy is the recommen…
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In this podcast, authors discuss how to ensure that individual patients’ needs and concerns are addressed when it comes to shared decision-making on treatment for metastatic breast cancer. Including an overview of different approaches for initial consultations, strategies for tailoring conversations based on a patient’s background or health literac…
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Authors Dr Peter Black and Dr Bernie Eigl aim to provide an overview of the non-muscle-invasive bladder cancer (NMIBC) landscape with a focus on high-risk NMIBC. This includes understanding the diagnosis and current treatment approaches with a focus on the medical needs and high-risk NMIBC treatment, highlighting the potential challenges associated…
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In this podcast, authors Dr Luca Bertolaccini and Dr Giulio Metro touch upon the need for a standard definition of resectability in patients with resectable stage III non-small cell lung cancer (NSCLC). This podcast gives the perspectives of a thoracic surgeon and an oncologist, and suggests a shared agreement between two of the main actors involve…
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In this podcast, author Dr Kai Hübel discussed a case of a patient with high-risk relapse follicular lymphoma. This discussion outlines the potential effectiveness of chimeric antigen receptor (CAR)-T cell therapy in relapsed/refractory follicular lymphoma. This podcast is adapted from a vodcast article published open access in Oncology and Therapy…
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Challenge conventional wisdom on fat loss with a fresh perspective that prioritizes mental and emotional health as the foundation for physical change. This episode Amy discusses with Jared the critical role of addressing underlying issues like binge eating, emotional eating, and self-sabotage before embarking on a weight loss journey. Learn about t…
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BUFFALO, NY- March 20, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on March 14, 2024, entitled, “Analytical validation of NeXT Personal®, an ultra-sensitive personalized circulating tumor DNA assay.”In this new study, researchers Josette Northcott, Gabor Bartha, Jason Harris, Conan Li, Fabio C.P. Navarro, Rachel Marty Pyke…
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BUFFALO, NY- March 19, 2024 – A new #research perspective was #published by Mikhail V. Blagosklonny M.D., Ph.D., from Roswell Park Comprehensive Cancer Center in Oncotarget's Volume 15 on March 15, 2024, entitled, “From osimertinib to preemptive combinations.”“Here, I suggest that while first-line osimertinib extends median progression-free surviva…
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BUFFALO, NY- March 18, 2024 – A new #researchpaper was #published in Oncotarget's Volume 15 on March 14, 2024, entitled, “G-quadruplex landscape and its regulation revealed by a new antibody capture method.”In this new study, researchers Subhamoy Datta, Manthan Patel, Chakkarai Sathyaseelan, Chandrama Ghosh, Akanksha Mudgal, Divyesh Patel, Thenmala…
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Learn how to navigate the challenges of staying healthy while traveling. Amy and Sara, both fitness coaches, discuss the nuances of traveling without compromising on their health goals. They cover practical advice on planning, restraint, and making informed choices. This episode is packed with real-world strategies for anyone looking to maintain th…
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The relentless search for effective cancer therapies has led to numerous breakthroughs in drug discovery and development. Advancements have emerged in recent years through the promising avenue of combination therapy, where two or more drugs are used synergistically to enhance their collective therapeutic effect. This strategy has shown significant …
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Amy revisits her journey with breast implants, sharing the unexpected turn of deciding to have them reinserted after previous removal due to concerns about breast implant illness. With raw honesty, she explores the intricate balance between physical appearance and mental health, offering a nuanced perspective on cosmetic surgery. This episode unpac…
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BUFFALO, NY- March 11, 2024 – Impact Journals publishes #scholarly journals in the #biomedical sciences with a focus on all areas of cancer and aging research. Oncotarget is one of the most prominent journals published by Impact Journals. Impact Journals will be participating as an exhibitor at the American Association for Cancer Research (AACR) An…
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Coach and Therapist, Isaac Ho shares the journey of uncovering the hidden links between past traumas and physical health issues. Through personal experiences and professional insights, this episode sheds light on how unresolved emotional pain can manifest in the body. It delves into the transformative power of holistic healing practices, emphasizin…
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In this podcast, Elias Jabbour from the University of Texas MD Anderson Cancer Center, Houston, TX, and Matthias Stelljes Universitätsklinikum Münster, Münster, Germany summarize and highlight some of the recent findings on the use of inotuzumab ozogamicin as induction therapy for older adults with newly diagnosed acute lymphoblastic leukemia (ALL)…
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Amy Ledin raises an intriguing question at the heart of today's discussion: 'What new habits are now a part of your daily life that weren't here before?' In this thought-provoking episode, Amy discusses the journey of evolving one's identity to foster a healthier, more fulfilling life. She shares insights into the psychological shifts necessary for…
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BUFFALO, NY- March 6, 2024 – A new #researchpaper was #published in Oncotarget's Volume 15 on March 5, 2024, entitled, “GZ17-6.02 interacts with proteasome inhibitors to kill multiple myeloma cells.”In this new study, researchers Laurence Booth, Jane L. Roberts, Cameron West, and Paul Dent from Virginia Commonwealth University and Genzada Pharmaceu…
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BUFFALO, NY- March 4, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on February 22, 2024, entitled, “Sacituzumab govitecan plus platinum-based chemotherapy mediates significant antitumor effects in triple-negative breast, urinary bladder, and small-cell lung carcinomas.”Sacituzumab govitecan (SG) is an antibody-drug conjugat…
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This podcast is published open access in Ophthalmology and Therapy and is fully citeable. You can access the original published podcast article through the Ophthalmology and Therapy website and by using this link. All conflicts of interest can be found online. Open Access This podcast is licensed under a Creative Commons Attribution-NonCommercial 4…
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Amy Ledin delves into the complexities of her family's significant move back to Canada, shedding light on the emotional and logistical challenges faced together. From tackling immigration hurdles to confronting the difficulties of reuniting their family across borders, Amy shares the story of their journey with honesty and vulnerability. This episo…
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BUFFALO, NY- February 28, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on February 22, 2024, entitled, “Prevalence and spectrum of germline BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula (Southern Italy): a matter of preventive health.”In this new exploratory and descriptive study, researc…
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BUFFALO, NY- February 26, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on February 8, 2024, entitled, “GZ17-6.02 interacts with bexarotene to kill mycosis fungoides cells.”In this new study, researchers Michael R. Booth, Laurence Booth, Jane L. Roberts, Cameron West, and Paul Dent from Virginia Commonwealth University and G…
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Betel quid chewing, a traditional custom widely practiced in South Asia, Southeast Asia, the Asia-Pacific region, and East Africa for centuries, involves the consumption of raw areca nut mixed with slaked lime and wrapped in a betel leaf. This habit is particularly popular in certain regions, including Northeast India, where the areca nut is raw, w…
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BUFFALO, NY- February 21, 2024 – A new research #perspective was #published in Oncotarget's Volume 15 on February 8, 2024, entitled, “Combining causal and correlative approaches to discover biomarkers of response to paclitaxel.”As discussed in this new paper, researchers Alberto Moscona-Nissan, Karl J. Habashy, Victor A. Arrieta, Adam M. Sonabend, …
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BUFFALO, NY- February 19, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on February 5, 2024, entitled, “Neurotrophic-tyrosine receptor kinase gene fusion in papillary thyroid cancer: A clinicogenomic biobank and record linkage study from Finland.”Selective tropomyosin receptor kinase (TRK) inhibitors are approved targeted th…
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Crossref is a non-profit organization that logs and updates citations for scientific publications. Each month, Crossref identifies a list of the most popular Oncotarget papers based on the number of times a DOI is successfully resolved. Below are Crossref’s Top 10 Oncotarget DOIs published in 2023.10: Everolimus downregulates STAT3/HIF-1α/VEGF path…
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BUFFALO, NY- February 14, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on February 5, 2024, entitled, “Genetic and therapeutic landscapes in cohort of pancreatic adenocarcinomas: next-generation sequencing and machine learning for full tumor exome analysis.”About 7% of all cancer deaths are caused by pancreatic cancer (PCa)…
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BUFFALO, NY- February 12, 2024 – A new research paper was published in Oncotarget's Volume 15 on February 5, 2024, entitled, “Differential expression of Mad2 gene is consequential to the patterns of histone H3 post-translational modifications in its promoter region in human esophageal cancer samples.”Raw areca nut (AN) consumption increases esophag…
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Thyroid cancer is a complex disease with various subtypes and clinical presentations. While some cases can be successfully treated with standard therapy, others present challenges due to resistance to treatment and the development of aggressive forms of the disease. In a new research perspective, researchers Mark Lee and Luc GT Morris from New York…
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This podcast is published open access in Dermatology and Therapy and is fully citeable. You can access the original published podcast article through the Dermatology and Therapy website and by using this link: https://link.springer.com/article/10.1007/s13555-023-01093-w. All conflicts of interest can be found online. Open Access This podcast is lic…
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BUFFALO, NY- February 7, 2024 – A new #research perspective was #published in Oncotarget's Volume 15 on February 5, 2024, entitled, “Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma.”In this new paper, researchers Ashley Del Dosso, Elizabeth Tadevosyan, and James R. Berenson from ONCOtherapeutics, Be…
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BUFFALO, NY- February 5, 2024 – A new #editorial paper was #published in Oncotarget's Volume 15 on January 24, 2024, entitled, “The fate of drug discovery in academia; dumping in the publication landfill?”In this new editorial, researchers Uzma Saqib, Isaac S. Demaree, Alexander G. Obukhov, Mirza S. Baig, Amiram Ariel, and Krishnan Hajela, from Dev…
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