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Podcast # 353: Xofluza
Manage episode 212835239 series 1397179
Content provided by medicalminute and Emergency Medical Minute. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by medicalminute and Emergency Medical Minute or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
Author: Sam Killian, MD
Educational Pearls:
- Japan recently approved baloxavir marboxil (Xofluza), which may potentially "kill" Flu A/B within 24 hours
- Recent RCT trial showed superiority over oseltamavir (Tamiflu) in cessation of viral shedding (24 vs 72 hours)
- Compared to placebo, superior in time to symptom resolution (53.7 vs 80.7 hours)
- Administered as single dose
- Yet to be considered for FDA approval
References
Portsmouth S, Kawaguchi K, Arai M, Tsuchiya K, Uehara T. Cap-dependent Endonuclease Inhibitor S-033188 for the Treatment of Influenza: Results from a Phase 3, Randomized, Double-Blind, Placebo- and Active-Controlled Study in Otherwise Healthy Adolescents and Adults with Seasonal Influenza. Open Forum Infectious Diseases. 2017;4(Suppl 1):S734. doi:10.1093/ofid/ofx180.001.
1072 episodes
Share
Manage episode 212835239 series 1397179
Content provided by medicalminute and Emergency Medical Minute. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by medicalminute and Emergency Medical Minute or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
Author: Sam Killian, MD
Educational Pearls:
- Japan recently approved baloxavir marboxil (Xofluza), which may potentially "kill" Flu A/B within 24 hours
- Recent RCT trial showed superiority over oseltamavir (Tamiflu) in cessation of viral shedding (24 vs 72 hours)
- Compared to placebo, superior in time to symptom resolution (53.7 vs 80.7 hours)
- Administered as single dose
- Yet to be considered for FDA approval
References
Portsmouth S, Kawaguchi K, Arai M, Tsuchiya K, Uehara T. Cap-dependent Endonuclease Inhibitor S-033188 for the Treatment of Influenza: Results from a Phase 3, Randomized, Double-Blind, Placebo- and Active-Controlled Study in Otherwise Healthy Adolescents and Adults with Seasonal Influenza. Open Forum Infectious Diseases. 2017;4(Suppl 1):S734. doi:10.1093/ofid/ofx180.001.
1072 episodes
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Similar to Emergency Medical Minute
Unseeable forces control human behavior and shape our ideas, beliefs, and assumptions. Invisibilia—Latin for invisible things—fuses narrative storytelling with science that will make you see your own life differently.
…
continue reading
Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
…
continue reading
Introducing the BODi® Partner Podcast, the official podcast channel devoted exclusively to BODi Partners. From archives of the BODi Wake-Up Call, I Am BODi stories, and What I Know Now success tips from seasoned Partners, this podcast is your one-stop source for personal development, business training and peer-to-peer inspiration. Ready to explode your business? Tune in regularly to our official podcast and join the ranks of those transforming their lives and the lives of others!
…
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PT Inquest is an online journal club. Hosted by Jason Tuori, Megan Graham, and Chris Juneau, the show looks at an article every week and discusses how it applies to current physical therapy practice.
…
continue reading
Trusted ER doctor Brian Goldman brings you honest and surprising stories that can change your health and your life. Expect deep conversations with patients, families and colleagues that show you what is and isn't working in Canadian healthcare. Guaranteed you’ll learn something new. Episodes drop every Friday.
…
continue reading
Hannah Fry and Dara O'Briain tackle listener's conundrums with the power of Science!
…
continue reading
There are a lot of fads, blogs and strong opinions, but then there’s SCIENCE. Science Vs is the show from Gimlet that finds out what’s fact, what’s not, and what’s somewhere in between. We do the hard work of sifting through all the science so you don't have to and cover everything from 5G and Pandemics, to Vaping and Fasting Diets.
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…
continue reading
I Tyngre Radio snackas det om styrketräning. Punkt. Värdar är Alex Danielsson och Andreas Guiance.
…
continue reading
Expert insight on health, performance, longevity, critical thinking, and pursuing excellence. Dr. Peter Attia (Stanford/Hopkins/NIH-trained MD) talks with leaders in their fields.
…
continue reading
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Go offline with the Player FM app!
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