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Podcast 662: Droperidol for Sedation

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Manage episode 290487773 series 1397179
Content provided by medicalminute and Emergency Medical Minute. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by medicalminute and Emergency Medical Minute or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

Contributor: Aaron Lessen, MD

Educational Pearls:

  • Droperidol for sedation in agitated patients in the emergency department was studied compared to ziprasidone (Geodon) and lorazepam (Ativan)
  • Double-blinded RCT showed droperidol was 65% effective to get patients to a good level of sedation in 15 minutes compared to ativan and geodon which were 25-35% effective
  • Droperidol had less respiratory depression and prolongation of the QT compared to Ativan and Geodon

References

Martel ML, Driver BE, Miner JR, Biros MH, Cole JB. Randomized Double-blind Trial of Intramuscular Droperidol, Ziprasidone, and Lorazepam for Acute Undifferentiated Agitation in the Emergency Department. Acad Emerg Med. 2021 Apr;28(4):421-434. doi: 10.1111/acem.14124. Epub 2020 Oct 5. PMID: 32888340.

Summarized by John Spartz, MS3 | Edited by Erik Verzemnieks, MD

  continue reading

1051 episodes

Artwork
iconShare
 
Manage episode 290487773 series 1397179
Content provided by medicalminute and Emergency Medical Minute. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by medicalminute and Emergency Medical Minute or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

Contributor: Aaron Lessen, MD

Educational Pearls:

  • Droperidol for sedation in agitated patients in the emergency department was studied compared to ziprasidone (Geodon) and lorazepam (Ativan)
  • Double-blinded RCT showed droperidol was 65% effective to get patients to a good level of sedation in 15 minutes compared to ativan and geodon which were 25-35% effective
  • Droperidol had less respiratory depression and prolongation of the QT compared to Ativan and Geodon

References

Martel ML, Driver BE, Miner JR, Biros MH, Cole JB. Randomized Double-blind Trial of Intramuscular Droperidol, Ziprasidone, and Lorazepam for Acute Undifferentiated Agitation in the Emergency Department. Acad Emerg Med. 2021 Apr;28(4):421-434. doi: 10.1111/acem.14124. Epub 2020 Oct 5. PMID: 32888340.

Summarized by John Spartz, MS3 | Edited by Erik Verzemnieks, MD

  continue reading

1051 episodes

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