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Ep. 15 | What Are Mosaic Embryos?

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Manage episode 237067657 series 2503938
Content provided by Mark P. Trolice, M.D., Mark P. Trolice, and M.D.. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Mark P. Trolice, M.D., Mark P. Trolice, and M.D. or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

Mosaic is the term assigned to embryos found to possess both normal and abnormal cells during preimplantation genetic screening (PGS). PGS is typically completed on day five of embryo development for in vitro fertilization (IVF). Through PGS, embryologists can detect, and often diagnose, potential chromosomal abnormalities including the presence of Down syndrome. Until very recently, any cell with noted defects was discarded and not considered for IVF transfer.

However, recent developments have led doctors to suspect that these abnormal cells may be viable for transfer after all. In this episode, Eric Forman, M.D., medical and laboratory director at Columbia University Fertility Center, joins host Mark P. Trolice, M.D., to discuss why there has been some success in the transfer of mixed quality (mosaic) embryos, and why many of the births have gone on to produce healthy, normal babies.

Tune in to discover:

  • What mosaic embryos are and where they come from
  • The benefits (and limitations) of preimplantation genetic testing
  • Why mosaic embryos may be viable for IVF transfer
  • When women and couples might consider using mosaic embryos for transfer
  continue reading

25 episodes

Artwork
iconShare
 
Manage episode 237067657 series 2503938
Content provided by Mark P. Trolice, M.D., Mark P. Trolice, and M.D.. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Mark P. Trolice, M.D., Mark P. Trolice, and M.D. or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

Mosaic is the term assigned to embryos found to possess both normal and abnormal cells during preimplantation genetic screening (PGS). PGS is typically completed on day five of embryo development for in vitro fertilization (IVF). Through PGS, embryologists can detect, and often diagnose, potential chromosomal abnormalities including the presence of Down syndrome. Until very recently, any cell with noted defects was discarded and not considered for IVF transfer.

However, recent developments have led doctors to suspect that these abnormal cells may be viable for transfer after all. In this episode, Eric Forman, M.D., medical and laboratory director at Columbia University Fertility Center, joins host Mark P. Trolice, M.D., to discuss why there has been some success in the transfer of mixed quality (mosaic) embryos, and why many of the births have gone on to produce healthy, normal babies.

Tune in to discover:

  • What mosaic embryos are and where they come from
  • The benefits (and limitations) of preimplantation genetic testing
  • Why mosaic embryos may be viable for IVF transfer
  • When women and couples might consider using mosaic embryos for transfer
  continue reading

25 episodes

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