Nausea Relief Strategies for GLP-1 Agonist Medications

The Obesity Guide with Matthea Rentea MD

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Nausea is one of the most frequently reported side effects of GLP-1 agonist medications used in obesity treatment, such as Zepbound, Wegovy, Mounjaro, and Victoza. Although not everyone will experience it, the nature of these anti-obesity medications can often lead to nausea, caused by the slowing of gastric emptying.

Anyone who has experienced nausea before, especially during pregnancies, will understand just how debilitating it can be, impacting your daily life and work. So, what level of nausea should you expect from weight loss medications? And how can we effectively manage this side effect? In this episode, I'm sharing practical strategies to mitigate nausea, advice on when to seek medical advice, and insights on using medications like Zofran to ease discomfort.

Remember: This podcast provides general educational information. Always consult your doctor and medical team for personalized advice and guidance on any symptoms you’re experiencing.
References

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GHOST®
Audio Stamps
00:58 - Dr. Rentea explains why most anti-obesity medications contribute in some capacity to nausea and describes the nature and impact of this common side effect.
06:05 - Dr. Rentea encourages us to be mindful of the types of foods consumed while on anti-obesity medications as certain foods can trigger nausea more than others.
08:20 - We hear the importance of hydration in managing nausea and Dr. Rentea explains how cold drinks and electrolyte products can alleviate symptoms.
13:05 - Dr. Rentea shares some general tips and changes you can make to your diet to help manage nausea.
17:35 - Dr. Rentea stresses that vomiting is not normal and urges consulting a doctor if it occurs, as adjustments to eating habits or medication dosage may be necessary.
Quotes
“You need to be spacing out your food because most people will not be able to eat these bigger meals at once.” - Matthea Rentea MD
“If you are avoiding fried stuff, greasy, or really high sugar foods, it's going to be really helpful.” - Matthea Rentea MD
“Vomiting is never normal. You always need to talk to your doctor.” - Matthea Rentea MD
“Electrolytes can oftentimes be helpful for nausea and headaches.” - Matthea Rentea MD
“Something like Zofran, if you're not allergic, is just nice to have in your toolkit. But you need your physician to walk you through when and how to use it.” - Matthea Rentea MD

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