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My DNA Coach Podcast I Jonny Deacon I Health I Fitness I DNA Testing I Blood Testing |A.I |DEXA I Kolbe A Index | Personal Training
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EPISODE 135 - DNA FOCUS - TRHR
Archived series ("Inactive feed" status)
When? This feed was archived on January 07, 2022 22:53 (). Last successful fetch was on May 22, 2020 01:28 ()
Why? Inactive feed status. Our servers were unable to retrieve a valid podcast feed for a sustained period.
What now? You might be able to find a more up-to-date version using the search function. This series will no longer be checked for updates. If you believe this to be in error, please check if the publisher's feed link below is valid and contact support to request the feed be restored or if you have any other concerns about this.
Manage episode 191498303 series 1184045
The next gene in our “DNA Focus” series to get put under the spotlight is TRHR. This gene encodes for the thyrotropin-releasing hormone receptor, which is a receptor for a hormone called thyrotropic-releasing hormone (TRH), which is released from the hypothalamus. When TRH binds to TRHR, it causes a number of different cellular signals to occur, which in turn stimulate the thyroid gland to produce thyroxin, which in turn plays a role in the growth and development of skeletal muscle. Small changes in the TRHR gene mean that the hormone receptor is not quite as good at binding with TRH, which in turn can reduce or limit the amount of muscle that can be produced following training.
Genotype
Effect
Training Modification
GG
Most likely to achieve favourable improvements in lean body mass and muscle growth with strength training programmes.
Strongest bias training towards to power end of the spectrum.
GT
A more moderate form of the GG genotype; a good response to strength training, but not as good as CC
Moderate bias towards power-based training
TT
Least responsive genotype in terms of lean body mass increases following strength training
Follow a mixed approach towards strength training.
Resources & Studies Mentioned
165 episodes
Archived series ("Inactive feed" status)
When? This feed was archived on January 07, 2022 22:53 (). Last successful fetch was on May 22, 2020 01:28 ()
Why? Inactive feed status. Our servers were unable to retrieve a valid podcast feed for a sustained period.
What now? You might be able to find a more up-to-date version using the search function. This series will no longer be checked for updates. If you believe this to be in error, please check if the publisher's feed link below is valid and contact support to request the feed be restored or if you have any other concerns about this.
Manage episode 191498303 series 1184045
The next gene in our “DNA Focus” series to get put under the spotlight is TRHR. This gene encodes for the thyrotropin-releasing hormone receptor, which is a receptor for a hormone called thyrotropic-releasing hormone (TRH), which is released from the hypothalamus. When TRH binds to TRHR, it causes a number of different cellular signals to occur, which in turn stimulate the thyroid gland to produce thyroxin, which in turn plays a role in the growth and development of skeletal muscle. Small changes in the TRHR gene mean that the hormone receptor is not quite as good at binding with TRH, which in turn can reduce or limit the amount of muscle that can be produced following training.
Genotype
Effect
Training Modification
GG
Most likely to achieve favourable improvements in lean body mass and muscle growth with strength training programmes.
Strongest bias training towards to power end of the spectrum.
GT
A more moderate form of the GG genotype; a good response to strength training, but not as good as CC
Moderate bias towards power-based training
TT
Least responsive genotype in terms of lean body mass increases following strength training
Follow a mixed approach towards strength training.
Resources & Studies Mentioned
165 episodes
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