Welcome to Basics to Brilliance, the Haematology podcast created to supplement & bolster your knowledge for the FRCPath Part 1. Featuring a two way, non-didactic conversational-style Q&A between the SpR and SHO, this podcast will be your pocket companion no matter where you are. We aim to cover: - Malignant and non-malignant topics - The whole syllabus for FRCPath part 1 - Review UK guidelines - Go into science/lab detail - Discuss how guidelines often translate into practice - Review and ap ...
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This podcast is a follow-up to my book. I am here to bring messages to the deaf and visions to the blind. We have lost sense of who we are as human beings and frequently misunderstand this experience because of how society has poised us to be unaware of the very thing we live in. In our struggles to find our ways past the traumas that likely began in childhood, we’ve developed a disconnect as we aged that we call by many names – such as, anxiety, depression, and fear. But, it’s simply mental ...
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How Not is the brainchild of two gobby Scottish creatives, Kim Macari and Luca Manning, who like to talk about the BIG stuff. We thought you might like to listen...So here we are. Our mission is to always be Good Troublemakers, to think big and to ask - How Not?! Each episode, we pick something BIG to talk about. Sometimes that's an issue or idea that's been keeping us awake at night (like the right to Protest, The Punk Movement or Universal Basic Income...) and sometimes it's a person who t ...
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The Toilet Paper Salesman Podcast serves as your companion on the journey of life, focusing on areas that bring peace, joy, fulfillment, and success in both your business and personal lives. The podcast episodes will cover topics such as: 1. Sales Techniques and Skills 2. Leadership Development 3. Special interests, simple pleasures: What makes your life worth living? 4. Discover your life’s calling. We will feature guests who will join the discussions on these subjects when relevant. Tune i ...
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From Basics to Brilliance in Salesmanship
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Send us a Text Message. Ever wondered why some salespeople consistently outperform others? Discover the secret sauce to becoming a standout in sales with our latest episode. I reveal that mastering the basics is your key to success. Uncover the three pillars of great salesmanship: showing up, following up, being likable and credible, and perfecting…
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Connect With E Here! This one may be too harsh for some of you, but the caring and wise beauty of my passion for humanity to do better for themselves that you know and love in this podcast is weaved in. No one is expecting people to divulge their entire lives to random people or even strangers, but if a friend asks you how you’re doing, be mf’n hon…
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Let’s Love Each Other then Fight These Peeholes Together: They are the Reason Our Lives are a Sloppy, Wet Mess.
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15:54
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Connect With E Here! There’s a giant web of collusion. If people are eating unhealthy food, they’ll eventually fall into the healthcare arena. Then, we have to deal with more assfuckery. We already know insurance companies will deny life-saving drugs and treatments. We know that doctors will only see you if they can bill insurance, so they’ll let y…
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Addiction: Being a Junkie isn't #LifeGoals
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21:00
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Connect With E Here! Self-explanatory, but I always have to explain. Souls born from the uterus of a junkie, my generation used to call crackhead babies. These are the ones with the innate propensity to follow the ashy apple tree they fell from. This is a medical circumstance. This episode talks about people not of this beginning but make it their …
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Connect With E Here! This is an excerpt from my book, "How to Not Give a Shit, and Not Be a Dumb Ass in the Process: The Ultimate Guidebook on Being a Better Human." Check it out if you enjoyed these couple of minutes. Amazon link below in the sign-off. Try out our new text messaging feature directly above the episode descriptions if you have some …
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Send us a Text Message. Ever wondered what you can learn from a Toilet Paper Salesman? Join me, Mike Mirarchi, as I kick off the first episode of the Toilet Paper Salesman Podcast and reveal the surprising journey that led me here. From growing up in a middle-class family to navigating the unpredictable path to college and a successful sales career…
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Polycythaemia- red cell # Erythrocytosis – in red cell mass Absolute Erythrocytosis - M: Hct >0.60 or >0.52 + RCM >25% of mean - F: Hct >0.56 or >0.48 + RCM >25% of mean Apparent Erythrocytosis - Men: Hct >0.52 + normal RCM - Women: Hct >0.48 + normal RCM Relative erythrocytosis -Normal RCM + Reduced plasma volume (pathological dehydration) M>F Med…
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- Synchronous CNS and systemic lymphoma at initial presentation (treatment-naïve; TN-SCNSL) - CNS relapse without recurrent systemic lymphoma (relapsed isolated CNS lymphoma; RI-SCNSL) - Relapsed concomitant systemic and CNS disease following treatment for systemic lymphoma (RC-SCNSL) Generally hybrid disease Investigations - MRI Head w gadolinium …
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CNS Lymphomas 1% of all NHL 3% of all Brain tumours Most common subtype (90%) is DLBCL Clinical division: 1. 1* CNS lymphoma, 2. 2* CNS lymphoma - TN-SCNSL - RI-SCNSL - RC-SCNSL 3. Immune deficiency assoc- HIV; better prog. Presentation: - SOL Sx - Raised ICP: morning headaches w N+V - Neuropsych, Behavioural, Memory, Language - Focal motor + Strok…
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Chronic MyeloMonocytic Leukemia (not CML) Persistently high monocyte count- 3 months Most frequent MDS/Myeloproliferative neoplasms – a cross between the two Median age 72 Median survival 20-40 months Transformation to AML (15-30%) WHO definition of CMML: 1. Excess monocytes- persistent over 3 months, ≥ 1 - Monocytes 10% of total WC count 2. Dyspla…
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Chronic Lymphocytic Leukemia (CLL)- Chronic Relapsing Remitting Most common leukemia in adults Incurable but treatable *Remember Supportive Care* Median age of 72 M > F 80% incidental SLL: lymphocytes in lymph nodes and spleen instead of blood Presentation: 1) Fatigue 2) B symptoms 3) High WC 4) Cytopenias (Marrow infiltrate, AIHA, ITP, Hyposplenis…
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Faith in Self (The Feminine Energy of Just Being)
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Connect With E Here! While this episode was in the spirit of closing out another women's month, there was more on my heart to share. There is yin and yang to everything. Duality and balance in all. Faith is the energy of believing in the integrity of this truth. We can have faith in many external things, but they mean nothing if we don’t have faith…
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Connect With E Here! Another recording from 2021, as we are watching and experiencing out of control wildfires; earthquakes in places that are not normally busy with seismic activity; volcanoes waking up from their million- or billion-year slumbers; and water raising from everywhere in tsunamis; numerous and out of control storms; and the global se…
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Connect With E Here! The same stories seemingly cross many major cultures of the world, further showing us we are all made from the same inaugural thread weaved. The Ark of the Covenant is very similar to a purportedly older Egyptian technological device called, the Osiris Device, which was said to have the same function of communicating with God/t…
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Connect With E Here! For millennia, the Catholic church has had its hand in everyone’s life, including those who are not of their grain. This hand has infiltrated our homes, politics, and many societies’ norms. However, not in any good way. Religion should never be something abusive and vicious. It is what people cling to for understanding life and…
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Connect With E Here! This episode is about going back to basics – like, elementary basics. Things don’t seem to sink in until the nexus of the thought is made as plainly as possible for people to get it. Nothing in adulthood makes sense, so we need to view it from untainted eyes and minds. As I like to say, “life is an ouroboros.” Sometimes, we nee…
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Connect With E Here! This episode was recorded in 2021. I have to laugh because, as I'm highly intuitive, I brought this shit to light in my book and on this episode just to be watching it unfold two years later. Everything I say is truth. The Golden Rule applies to anyone and every business. You can't treat your stakeholders like shit then expect …
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Connect With E Here! This episode was recorded just over a year after my mother’s transcendence in 2021. People kept asking me if I was grieving and getting through everything. I questioned whether I was grieving because people kept asking, but these were other people’s questions. I grieved when I saw her soul leave in a dream then again at other t…
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Hello darling troublemakers! Yes, we are in fact back from hiatus with this brand new episode! Luca and Kim kicked off 2023 in true creative style by escaping the big smog and travelling to wondrous Wales. Luca still isn't exactly sure where they went but it was very very lovely indeed. Both Luca and Kim immersed themselves in creative adventure an…
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Connect With E Here! This one is self-explanatory. We need to be better to ourselves before we can be anything to anyone else. We have to be reminded to be kind to people. Last I checked, it should be paramount over what we get out of the deal. How soon we forget the Golden Rule but want to thump and wave Bibles in people's faces. We are selfish be…
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Connect With E Here! I’ve been called narcissistic, obnoxious, and more, but everything I say comes from a higher place of knowledge. I was put here to be the Universe’s vent of frustration. Through our fears, greed, and insecurities to name a few, we've fucked up so much beauty and perfection in us/the world that the regency has peaced out, and ar…
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Connect With E Here! Remember, repetition becomes habit. This episode brings everything full circle. We end these points (listen to "Pt. 1") right where we began. Fears, or those unreal thoughts, we created at some point in our lives that tell us that we aren’t good enough or worthy of something new, different, or that great was born from fear of f…
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Connect With E Here! Fear and procrastination is what keeps most people from realizing their purposes and allowing love in, especially to themselves. Whatever your soul’s purpose and (re)connecting to it, getting up today and acting within its goals and power is paramount to everything that is your human experience, with that (re)connection at the …
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Connect With E Here! Doing whatever that brings you joy has to be real. It can’t be something unconducive to successfully ending this part of your soul's journey with completed tasks. It cannot be an addiction that is not a result of your passion. It must be something that genuinely brings your heart happiness and joy. You can’t reach your goals hi…
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Connect With E Here! This fast-paced, verbally offensive episode is to get you all pumped and ready to tackle yourselves - your inner selves. Along with all of the pain in this world, I feel God’s frustration with us, and Her and the rest of the Divine Council’s) wtf energy. What exactly are we doing? Ask any person this and the answer is usually a…
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Connect With E Here! Omnipresent love comes in many forms. Don’t be the doctor who sends sick patients home because of their inability to pay. You find every technicality in the book to justify doing it. That patient then goes home, and dies. You've knowingly & willingly killed them. This isn't love of your fellow brothers & sisters. Do you feel go…
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Connect With E Here! This episode applies to everything from abortion rights, bigotry, to love and lots of things in between. In the examples I used, people who beat the odds are showing others in the world that they're not alone and it's very much possible to ascend above antiquated thought patterns in our society, and live a full, loving life des…
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Connect With E Here! Forgive my voice here. This was a busy day of fussing at people and recording multiple episodes about the dumb shit humans do. 2 Timothy ch. 2 explains everything we need to know about our lives and finding our Soul’s purpose - what we’re here to do. We must know that the resurrection is symbolic of our own evolution. Jesus she…
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Criticism vs. Critique: Giving Yourself the Finger
39:19
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Connect With E Here! I knew very early on what my path was, but it took the following years figuring out how to best live out that path and pinpointing the best route to take on it. It took lots of dealing with dirty, selfish people, psychological suffering, and internally dying and healing repeatedly (my cycle of resurrections) to achieve the leve…
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Connect With E Here! We have a tendency to self-sabotage ourselves then develop immensely paralyzing blockades to growth and well-being that we call fears. For example, some people have a fear of Mondays. Not just the typical, “Mondays,” but high anxiety-fueled fears about a Monday. It’s called lunaediesophobia. Things that give us extreme anxiety …
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Connect With E Here! Be advised, this episode was recorded in an office setting where I couldn't be loud & clear, so the second chapter is a little distorted but still audible, while the first & third are too clear, enough for listeners to hear my nose hairs swaying in the wind as I speak. Keep in mind I recorded the first few batches to come a yea…
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Connect With E Here! Life is about the journey and making it to the finish line, but there are things we need to do on that journey. If we run a marathon, we don’t just run. We still need to eat well days before, stretch prior, & hydrate during. However, we’re doing too much of nothing by doing a lot of busy work that have no real value to push us …
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Connect With E Here! Hola, everyone! The Androgynous King is here, finally. Don’t call me “them”. Call me by my name – the One. I'm going to take everyone on a journey untraversed by a great multitude. This is where you will be tackled with the choice of facing: your lower vibrating self or the face of the outcome of its work. Our lower selves have…
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WE ARE BACK BABYYYYY! For their grand return to the podcast airwaves, Kim & Luca decided to get together and discuss all things PUSSY RIOT. Dive in and hear them celebrate and discuss this trailblazing feminist punk collective of incredible troublemakers. Also mentioned : Joelle Taylor (@jtaylortrash) : joelletaylor.co.uk Monogramed / Hologramed no…
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Hello darling troublemakers! We are back! Welcome to this special archive episode featuring a chat Luca had back in Jan 2021 with the wonderful Xhosa Cole. Xhosa Cole is somewhat of a treasure on the young UK Jazz Scene. As well as being an incredible saxophone player, he is a kind, intelligent and genuine person who is well loved by many of his pe…
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How Not Pod Archives #1 : Stephanie Burrell
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Hello darling troublemakers! We are back! Welcome to this special archive episode featuring a chat Luca had back in December 2020 with the wonderful Stephanie Burrell. Stephanie is an incredible dancer, movement director, linguist, cook, storyteller, creative force of nature and source of joy. We’ll be sharing a couple of these cute lil archive epi…
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“You can't help it. An artist's duty, as far as I'm concerned, is to reflect the times.” This week, Kim and Luca discuss the legacy of the high priestess of soul : Nina Simone. An incredibly figure in musical history and undoubtedly a good troublemaker, it seemed only natural that we celebrate the life of this iconic woman as well as discuss some o…
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Kim and Luca ask each other some big questions as they tackle the Proust Questionnaire. What is your idea of happiness? Which trait do you most deplore in others? Which is the most over-rated virtue? Come find out the answers to these and many more... Check out David Bowie's answers here There's also a book that compiles the answers from 100 cultur…
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Catching up, sharing stories and the brilliance of Björk
54:27
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This week, Kim and Luca check in for a chit chat uncovering : Kim’s flawed film watching habits, the brilliance of Andrew Mcmillan’s poetry, Kim’s awakening to the one and only Bjork and much much more! Dive in xBy Kim Macari & Luca Manning
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Kim and Luca head back to the Priscilla Palace to discuss Abortion. With the issue never far from the headlines, it's back again with news that Texas is seeking to outlaw abortions after 6.5 weeks. Shame and fear make it difficult to talk about abortions and if there's one thing these Good Troublemakers hate most, it's shame. So come in and let's t…
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Kim and Luca sit down to discuss On Connection, the first non-fiction book by the great Kae Tempest. Focused on the need for connection and how we can work to foster it through creativity, the book is a moving and inspiring call to action in a world where we are overfed and under-nourished.By Kim Macari & Luca Manning
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With so much ground to cover, we couldn't fit it all into one episode so here's part TWO of our chat with the gorgeous Ian Shaw. We discuss ambition, Ian's work with refugees and muuuuuch more.By Kim Macari & Luca Manning
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This week, Kim and Luca hung out with the legendary Ian Shaw. An evening filled with laughs, home grown heritage tomatoes, Shaw special Negroni’s and tales of the highest candour. The best news? This is just part 1… dive in! Ian’s podcast ‘Not Even Music’ : https://open.spotify.com/show/2t95blHcfOXNigvmXZugx3?si=9CVUTh5FSM6J_BJ-Li_xjg&dl_branch=1 S…
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This week, Kim and Luca take a dive into discussing and celebrating the life and work of James Baldwin.By Kim Macari & Luca Manning
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Sisters of Perpetual Indulgence // Derek Jarman (with Adam Jeanes)
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Part 2 of our incredible afternoon spent with Adam Jeanes... In this episode, we highlight the amazing work of our favourite troublemaking nuns : 'The Sisters of Perpetual Indulgence' and celebrate the life of the iconic Derek Jarman. Adam tells us about his time spent as a Sister and how they came to canonise the great Derek Jarman before his deat…
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The Good Troublemakers are BACK! Rested, recharged and ready to take on the world once again, Kim and Luca present the first of a very special two parter featuring the glorious Adam Jeanes. Adam was Chair of The Pride Trust between 1993 and 1997, organising LGBT Pride London - the largest free to attend pop festival in Europe at that time. Ahead of…
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Last Day Of Term (Ryoji Ikeda, Football, James Baldwin...)
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It's the last day of term at the How Not Academy so before heading off on their summer break, Kim and Luca took a trip to Ryoji Ikeda's exhibition at 180 The Strand. We discuss the exhibition as well as a plethora on other things on our minds - football football chants - how do the fans learn them, is there a whatsapp group, is it a jam? Christian …
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Kim and Luca celebrate the life and work of trailblazing designer Alexander McQueen. Fashion should be a form of escapism and not a form of imprisonment From his formative days as an apprentice for Cornelius O'Callaghan on Savile Row, his pivotal meeting with Isabella Blow, spending unemployment benefits on fabrics to becoming Creative Director of …
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Let's get some eroticism all up in your business...! Taking Audre Lorde's seminal work from 1978, The Erotic as Power, Kim and Luca talk about eroticism and this is a BIG ONE. Every oppression in our history must corrupt or distort the sources of power that provide energy for change. (Audre Lorde) Among other things, we cover... What's the differen…
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It's time to celebrate everyone's favourite art world dissidents, The Guerilla Girls! Kim and Luca discuss the 'conscience of the art world', the anonymous art activist group The Guerilla Girls. Set up in the 1980s, their work has focused on the under-representation of women artists and artists of colour in the art world. Donning gorilla masks and …
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