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Empowered Patient Podcast with Karen Jagoda is a window into the latest innovations in digital health, the changing dynamic between doctors and patients, and the emergence of precision medicine. The show covers such topics as aging in place, innovative uses for wearables and sensors, advances in clinical research, applied genetics, drug development, and challenges for connected health entrepreneurs.
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Improving Targeting and Penetration of Cancer Therapies for Solid Tumors by Modifying Tumor Microenvironment with David Mazzo Lisata Therapeutics TRANSCRIPT
David Mazzo, President and CEO of Lisata Therapeutics, has a lead program focused on metastatic pancreatic ductal adenocarcinoma. The Lisata CendR Platform and drug certepetide efficiently augment the effects of chemotherapy and immunotherapies in the tumor microenvironment. Based on early findings, the future of cancer treatment may involve combin…
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Improving Targeting and Penetration of Cancer Therapies for Solid Tumors by Modifying Tumor Microenvironment with David Mazzo Lisata Therapeutics
18:04
18:04
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18:04
David Mazzo, President and CEO of Lisata Therapeutics, has a lead program focused on metastatic pancreatic ductal adenocarcinoma. The Lisata CendR Platform and drug certepetide efficiently augment the effects of chemotherapy and immunotherapies in the tumor microenvironment. Based on early findings, the future of cancer treatment may involve combin…
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Redefining Pain Management with Innovative Salonpas OTC Topical Analgesics with John Incledon Hisamitsu America TRANSCRIPT
John Incledon, President and CEO of Hisamitsu America, the makers of Salonpas, has seen enormous growth in the acceptance of over-the-counter topical pain management options since introducing the Salonpas analgesic patch in the US market 37 years ago. This growth is partly due to television ads featuring doctors touting the benefits of Salonpas for…
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Redefining Pain Management with Innovative Salonpas OTC Topical Analgesics with John Incledon Hisamitsu America
22:28
22:28
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22:28
John Incledon, President and CEO of Hisamitsu America, the makers of Salonpas, has seen enormous growth in the acceptance of over-the-counter topical pain management options since introducing the Salonpas analgesic patch in the US market 37 years ago. This growth is partly due to television ads featuring doctors touting the benefits of Salonpas for…
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Tech-Enabled Measurement-Informed Behavioral Healthcare Includes Therapy and Psychiatry with Dr. Doug Newton Rula Health TRANSCRIPT
Dr. Doug Newton is the Chief Medical Officer at Rula Health, a tech-enabled provider group that offers therapy, psychiatry, care coordination, and other supportive behavioral health services with a whole-person approach. Mental health disorders are diagnosed and managed using a combination of sound clinical judgment and measurement-informed care, w…
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Tech-Enabled Measurement-Informed Behavioral Healthcare Includes Therapy and Psychiatry with Dr. Doug Newton Rula Health
18:50
18:50
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Dr. Doug Newton is the Chief Medical Officer at Rula Health, a tech-enabled provider group that offers therapy, psychiatry, care coordination, and other supportive behavioral health services with a whole-person approach. Mental health disorders are diagnosed and managed using a combination of sound clinical judgment and measurement-informed care, w…
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Power of Personalized Polygenic Risk Scores to Predict and Prevent Diseases with Professor Sir Peter Donnelly Genomics plc TRANSCRIPT
Professor Sir Peter Donnelly, Founder and CEO of Genomics plc, aims to use cutting-edge polygenic risk scores to identify inherited DNA mutations and genetic predispositions that could lead to common diseases. In partnership with the MassMutual life insurance company, Genomics offers a voluntary test that provides personalized risk measures and adv…
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Power of Personalized Polygenic Risk Scores to Predict and Prevent Diseases with Professor Sir Peter Donnelly Genomics plc
18:02
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Professor Sir Peter Donnelly, Founder and CEO of Genomics plc, aims to use cutting-edge polygenic risk scores to identify inherited DNA mutations and genetic predispositions that could lead to common diseases. In partnership with the MassMutual life insurance company, Genomics offers a voluntary test that provides personalized risk measures and adv…
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Platform to Address Loneliness and Improve Care for Chronic Diseases with Oren Nissim Brook Health TRANSCRIPT
Oren Nissim, CEO and Co-Founder of Brook Health focuses on loneliness and its impact on individuals with chronic conditions, especially when access to support is limited. Societal stigma and guilt associated with chronic conditions often contribute to loneliness, which can include depression, lack of agency, and a sense of being alone. Brook Health…
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Platform to Address Loneliness and Improve Care for Chronic Diseases with Oren Nissim Brook Health
18:26
18:26
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Oren Nissim, CEO and Co-Founder of Brook Health focuses on loneliness and its impact on individuals with chronic conditions, especially when access to support is limited. Societal stigma and guilt associated with chronic conditions often contribute to loneliness, which can include depression, lack of agency, and a sense of being alone. Brook Health…
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Computational Biology Accelerating Cell and Gene Therapy Development with Kent Wakeford Form Bio TRANSCRIPT
Kent Wakeford, Co-CEO and Co-Founder of Form Bio, a company that provides computational solutions to scientists who are focused on cell and gene therapy to accelerate drug discovery and development, reduce costs, and ultimately make treatments more affordable for patients. Form Bio's in silico platform utilizes computational biology tools, bioinfor…
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Computational Biology Accelerating Cell and Gene Therapy Development with Kent Wakeford Form Bio
18:59
18:59
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Kent Wakeford, Co-CEO and Co-Founder of Form Bio, a company that provides computational solutions to scientists who are focused on cell and gene therapy to accelerate drug discovery and development, reduce costs, and ultimately make treatments more affordable for patients. Form Bio's in silico platform utilizes computational biology tools, bioinfor…
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Ram Krishnan, CEO of Valant, works with therapists, psychologists, psychiatrists, and nurse practitioners in the outpatient behavioral healthcare environment, which has significant unmet needs that can be addressed with technology. Scaling a mental health practice differs from other medical practices due to the frequency of visits and the need for …
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Scaling Behavioral Healthcare Practices Using Generative AI with Ram Krishnan Valant
19:36
19:36
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Ram Krishnan, CEO of Valant, works with therapists, psychologists, psychiatrists, and nurse practitioners in the outpatient behavioral healthcare environment, which has significant unmet needs that can be addressed with technology. Scaling a mental health practice differs from other medical practices due to the frequency of visits and the need for …
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Decision Intelligence Platform Uses AI to Guide Healthcare Treatment Choices with Fadi Micaelian Sparkdit and Dr. Andrew Fang TRANSCRIPT
Fadi Micaelian, CEO of Sparkdit, and Dr. Andrew Fang, Chief of Orthopedics at Kaiser South San Francisco, have joined together to help patients and doctors make better treatment decisions by considering trade-offs and patient preferences. The platform can help reduce bias and incorporate patient desires into care while considering comorbidities and…
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Decision Intelligence Platform Uses AI to Guide Healthcare Treatment Choices with Fadi Micaelian Sparkdit and Dr. Andrew Fang
22:43
22:43
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22:43
Fadi Micaelian, CEO of Sparkdit, and Dr. Andrew Fang, Chief of Orthopedics at Kaiser South San Francisco, have joined together to help patients and doctors make better treatment decisions by considering trade-offs and patient preferences. The platform can help reduce bias and incorporate patient desires into care while considering comorbidities and…
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Sufian Chowdhury, CEO of Kinetik, highlights how the non-emergency medical transportation industry, which has about 20,000 local transportation providers and over 400,000 drivers, plays a pivotal role in the healthcare continuum. Kinetik is bringing digital tools to this environment to provide scheduling and real-time information to an industry tha…
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Streamlining Non-Emergency Medical Transportation with Sufian Chowdhury Kinetik
16:49
16:49
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Sufian Chowdhury, CEO of Kinetik, highlights how the non-emergency medical transportation industry, which has about 20,000 local transportation providers and over 400,000 drivers, plays a pivotal role in the healthcare continuum. Kinetik is bringing digital tools to this environment to provide scheduling and real-time information to an industry tha…
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AI-Enabled Digital Front Door Technology Changing Patient Care Navigation and Nurse Triage with Piotr Orzechowski Infermedica TRANSCRIPT
Piotr Orzechowski, CEO of Infermedica, works with health insurance companies, technology partners, public payers, and ministries of health to provide digital care navigation tools that enhance the patient experience with a healthcare provider. The highlight is the development of digital front door technology to support patients in finding appropria…
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AI-Enabled Digital Front Door Technology Changing Patient Care Navigation and Nurse Triage with Piotr Orzechowski Infermedica
19:12
19:12
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Piotr Orzechowski, CEO of Infermedica, works with health insurance companies, technology partners, public payers, and ministries of health to provide digital care navigation tools that enhance the patient experience with a healthcare provider. The highlight is the development of digital front door technology to support patients in finding appropria…
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Incorporating Patient Perspective in Clinical Trial Design and Drug Development with Dr. Oren Cohen Fortrea TRANSCRIPT
Dr. Oren Cohen, President of Clinical Pharmacology and Chief Medical Officer at Fortrea, a global CRO spun-off from Labcorp, discusses the contract research environment and how it continues to change to meet the need for increased productivity in the development and testing of new drugs, devices, and treatments. One key goal is to work in close par…
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Incorporating Patient Perspective in Clinical Trial Design and Drug Development with Dr. Oren Cohen Fortrea
21:37
21:37
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Dr. Oren Cohen, President of Clinical Pharmacology and Chief Medical Officer at Fortrea, a global CRO spun-off from Labcorp, discusses the contract research environment and how it continues to change to meet the need for increased productivity in the development and testing of new drugs, devices, and treatments. One key goal is to work in close par…
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Dr. Will Chou, President and CEO of Passage Bio, is developing gene therapies for neurodegenerative diseases, with their lead product being PBFTO2, an AAV gene therapy for a specific genetic variant of frontotemporal dementia. They are also exploring the potential of raising progranulin levels to help patients with other neurodegenerative diseases.…
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Gene Therapies for Treating Neurodegenerative Diseases with Dr. Will Chou Passage Bio
18:40
18:40
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Dr. Will Chou, President and CEO of Passage Bio, is developing gene therapies for neurodegenerative diseases, with their lead product being PBFTO2, an AAV gene therapy for a specific genetic variant of frontotemporal dementia. They are also exploring the potential of raising progranulin levels to help patients with other neurodegenerative diseases.…
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Developing Oral Treatment for Rare Autoimmune Diseases with Ben Zimmer Priovant Therapeutics TRANSCRIPT
Ben Zimmer, CEO of Priovant Therapeutics, focuses on developing therapies for rare autoimmune diseases specifically dermatomyositis, which affects the skin, muscles, and organs, and non-infectious uveitis, a severe ocular inflammatory condition. While these conditions are symptomatically different, mechanistically, they have features in common rela…
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