Ben Orsburn and Ben Neely co-host a podcast series in a “fireside chat” format with prestigious proteomics researchers. The guests are great, the hosts are questionable.
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‘Translating Proteomics’ explores the science of proteomics and its growing impact on biological research, biomarker discovery, drug development, food and energy security, and a range of other timely topics. Hosts Parag Mallick Ph.D. and Andreas Huhmer Ph.D. of Nautilus Biotechnology aim to share their perspectives on important issues in proteomics, deepen your love of science, and prompt you to question assumptions about what may be possible.
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Speaking of Mol Bio, a podcast series from Thermo Fisher Scientific, discusses trending applications in science and the molecular biology aspects of those applications. Our hosts delves in to deep discussion with CEOs, R&D scientists, researchers, and key opinion leaders across the globe. Speaking of Mol Bio helps scientific curious people - from all scientific and non-scientific backgrounds - understand how modern molecular biology applications can help push the boundaries in medicine, scie ...
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The Journal of Proteome Research integrates the fields of chemistry, mathematics, applied physics, biology, and medicine in order to better understand the function of proteins in biological systems.
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Proteomics in Proximity discusses the intersection of proteomics with genomics for drug target discovery, the application of proteomics to reveal disease biomarkers, and current trends in using proteomics to unlock biological mechanisms. Co-hosted by Olink's Dale Yuzuki, Cindy Lawley and Sarantis Chlamydas.
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The PROTEOMICS podcast is a free audio show featuring top articles from PROTEOMICS (www.proteomics-journal.com), one of the key journals in proteomic research. Listen every month to interviews with leading scientists around the world to open up the fascinating world of proteomics through their ideas and research. Get to know the PROTEOMICS family with the new addition to the podcast featuring Clinical Applications, providing insight into the application of proteomics to the study of human di ...
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On this podcast leading scientist, clinicians and entrepreneurs share their thoughts on the progress of personalized medicine. With our guests, we discuss new technologies for targeted treatments and diagnostics, their benefits for patients and clinicians and related implementation challenges.
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Biotech2050 Podcast is a think tank chronicling the disruptions changing the biotech industry over the next 50 years.
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Nextflow is a leading open-source workflow orchestrator that simplifies writing and deploying compute and data-intensive pipelines at scale on any infrastructure. In this podcast we discuss news in the Nextflow ecosystem and speak with pioneers in the field.
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Exploring all things genetics. Dr Patrick Short, University of Cambridge alumnus and CEO of Sano Genetics, analyses the science, interviews the experts, and discusses the latest findings and breakthroughs in genetic research. To find out more about Sano Genetics and its mission to accelerate the future of precision medicine visit: www.sanogenetics.com
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Welcome to Talking Techniques! In this Podcast BioTechniques Digital Editor Tristan Free, interviews researchers at the forefront of their fields about the latest breakthroughs, controversies and conversations in the life sciences. From CRISPR to COVID-19, organoids to the microbiome, this podcast will explore the latest developments in the lab and interesting applications of techniques, while trying to determine how we can drive science forward in progressive and inventive ways. Hosted on A ...
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The vast field of sleep medicine is always evolving. Listen to Talking Sleep, a podcast of the American Academy of Sleep Medicine (AASM), to keep up on the latest developments in clinical sleep medicine and sleep disorders. Our host, Dr. Seema Khosla, medical director of the North Dakota Center for Sleep in Fargo, will take an in-depth look at issues impacting the diagnosis and treatment of sleep disorders. Episodes will feature conversations with clinicians, researchers, sleep team members ...
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Inside Biotech is an exciting podcast from BCLA, which focuses on the science behind SoCal’s most innovative new biotech companies. This semi-monthly podcast, hosted by Gabriella Rubert, Ph.D. Candidate at UCLA and Podcast Lead at BCLA, is the perfect way for anyone interested in LA’s biotech community to stay informed about current progress and developments. Episodes feature conversations with scientists, entrepreneurs, investors, and more about the cutting-edge science that goes on inside ...
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Joint SAUDI ARABIA-ICGEB workshop Trieste, 15 – 17 February 2015
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Welcome to Bio Bytes! Tune in for interviews with prominent scientists working at the intersection of Biology, Engineering, Medicine, Computer Science, and Mathematics. Check out our sister podcast "BioWorks" (https://anchor.fm/bioworks) for great discussions on life science-related business, investing, and policy. To support our podcast: https://securepay.cuit.columbia.edu/payment/pub/sponsor-sbi/https://securepay.cuit.columbia.edu/payment/pub/sponsor-sbi/ Please email sophiadeng0321@icloud ...
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After spending time in academia and exploring the unknown, the industry often seems too limited scientifically to those finishing a PhD. We will explore the bridge between the industry and academia to understand how basic scientific findings take shape into products and strategies. We will also follow the career paths of researchers who are in academia or outside of it, professionals that made their choice, followed it through and come to us to tell all about it. Academia or not? And if not, ...
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Revolutionizing Proteomics: Sujal Patel, Co-Founder & CEO of Nautilus, on Drug Development
36:55
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Sujal Patel, co-founder and CEO of Nautilus Biotechnology, discusses their innovative work in proteomics and its impact on drug development. Sujal shares his transition from tech to biotech, the formation of Nautilus with Parag Mallick, and their revolutionary approach using multi-affinity probes. The conversation highlights the importance of prote…
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Ep. 46 - B-sides - Dr. Phil Wilmarth
1:00:43
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As part of the non-sponsored sporadic "B-sides" series*, Ben and Ben sit down and talk with Dr. Phil Wilmarth, Oregon Health & Science University. (* this series is where we put guests we want to talk to but who do not fit within any sponsored series, but is still proteomics.... mostly)
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Expanding the Druggable Universe with Proteomics
26:22
26:22
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Despite incredible leaps in our understanding of molecular biology, the majority of drug development efforts still fail, and those that succeed often fail to return investment dollars. Proteomics has the potential to change that by providing high-resolution views of the biochemical drivers of biological function - proteins. In this episode of Trans…
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EP 143: Harnessing human data in drug development with Jakob Steinfeldt, Co-Founder and Chief Scientific Officer at Pheiron
36:17
36:17
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0:00 Intro to The Genetics Podcast 01:00 Welcome to Jakob and background on Pheiron 02:14 What made Jakob decide to start Pheiron, what the company does, and how his scientific background inspired him to found a start-up 5:24 Jakob’s excitement and inspiration around the power and potential of machine learning 07:07 Cardiology and heart failure as …
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Biotech Breakthroughs: Jeb Keiper, CEO of Nimbus Therapeutics, Discusses Their Innovative Journey
35:03
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Dive into this episode of Biotech 2050 where host Rahul Chaturvedi interviews Jeb Keiper, CEO of Nimbus Therapeutics. Discover Jeb's fascinating journey from MIT chemist to industry leader, as he shares insights into Nimbus’ groundbreaking work in ultra-rare diseases, innovative corporate structure, and strategic capital management. Emphasizing bol…
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Plastics are a modern miracle of science that have helped deliver both convenience and life-saving solutions. However, we must now grapple with the challenge of immense amounts of plastics in our waste streams and environment. How do we best deconstruct plastics to reusable or more bio-friendly molecules? This is the exact challenge being addressed…
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Antigen validation and T-cell receptor engineering for cancer immunotherapies
19:41
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This episode of the Talking Techniques podcast dives into the realm of cancer immunotherapies, focusing on antigen discovery and T-cell receptor engineering for T-cell therapies. Guiding us through the field is Jim Heath, President of the Institute for Systems Biology in Seattle, where he runs the Heath Lab, investigating fundamental immunology, an…
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EP 142: From genome to bedside: How genetics is transforming modern medical practice with Dr. Andrea Gropman
42:45
42:45
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0:00 Introduction 1:40 Andrea’s background and how she got into the field of genetics, neuroimaging, and metabolic disorders 4:00 Insights into Andrea’s clinical practice, including the diverse families and patients she serves and her approach to clinical decision-making 6:30 How genetics and genomics have changed the diagnostic journey in the last…
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Cytokines: from therapeutics to diagnostics
26:11
26:11
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In this episode of Talking Techniques, Ritwika Biswas, Field Application Scientist at Sino Biological US Inc. (PA, USA), discusses the use of cytokines in immunotherapy. Ritwika details the role of cytokines in the body, before going on to discuss how they can be used as therapeutics and to guide treatment decisions. Ritwika also shares how she thi…
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Episode 41: New syntax in Nextflow 24.04.
46:31
46:31
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Join us in exploring the latest Nextflow release, 24.04. Phil Ewels and Ben Sherman dive deep into the new updates in Nextflow’s most recent version. We discuss advanced retry strategies, job arrays, resourceLimits, Singularity’s OCI mode, and the game-changing Workflow Output Definition. We’re actively seeking feedback from the community on these …
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Key Considerations When Implementing an RPM program
40:18
40:18
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Remote patient monitoring codes have been active for a number of years. These have largely been used to monitor blood glucose levels via a continuous glucose monitor or to adjust heart failure medications via a connected digital scale. Dr. Charles Bae and Dr. Gabriela de Bruin discuss whether sleep medicine professionals should also use remote phys…
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EP 141: Bringing genomics to the clinic with Lori Orlando, Associate Prof at Duke University
43:24
43:24
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0:00 Intro to The Genetics Podcast 01:00 Welcome to Lori Orlando 03:00 Lori’s career: From mathematical modelling to genetics and family history 05:11 The study that revealed 20% of the general population is at a higher risk of disease than average and needs preventative care 07:36 The first five diseases that Lori started analysing through informa…
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As part of the non-sponsored sporadic "B-sides" series*, Ben and Ben sit down and talk with Dr. David Tabb, University Medical Center Groningen. (* this series is where we put guests we want to talk to but who do not fit within any sponsored series, but is still proteomics.... mostly)
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EP 140: The future of Electronic Health Records and data analysis with Ben Goldacre
52:51
52:51
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0:00 Intro to The Genetics Podcast 1:00 Welcome to Ben Goldacre 02:22 Ben’s open data projects at the Bennett Institute and the challenges they aim to tackle 04:03 Using Electronic Health Records (EHR) to help the National Health Service improve care 06:18 The importance of software development within healthcare data and how to manage salary scales…
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Episode 40: Origins of nf-core - SciLifeLab NGI
34:15
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Join us to hear Phil Ewels chat with Maxime Garciaand Franziska Bonath about how nf-core started at theNational Genomics Infrastructure (NGI) at SciLifeLab in Sweden.We chat about how the nf-core/sarek pipeline grew alongside and eventually joined nf-core,as well as the early days of nf-core bytesize talks and outreach organisation.Links:- SciLifeL…
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Reimbursement and clinical use of actigraphy
30:53
30:53
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The Actiwatch is a popular actigraphy device that is no longer sold or supported by Philips. Its discontinuation coincided with the launch of the AASM’s “Act on Actigraphy” campaign, which highlights the importance of actigraphy testing for sleep disorders and urges payers to reimburse health care professionals for this medical service. Dr. Paul Ra…
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EP 139: Rare disease breakthroughs using tRNA with Michelle Werner, CEO of Alltrna and CEO-Partner of Flagship Pioneering
44:42
44:42
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0:00 Intro to The Genetics Podcast. 01:00 Welcome to Michelle. 02:00 Sstop codon diseases and how are they characterised 03:45 Diseases caused by premature stop codons in haploinsufficient genes. 04:35 The role of transfer RNA technology in finding solutions for premature stop codon diseases. 06:16 How Alltrna is engineering tRNAs which can bind to…
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Harnessing Proteoforms to Understand Life's Complexity
24:34
24:34
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Proteins are far more than just the output of genes. They can be modified in myriad ways to produce millions of proteoforms with altered dynamics, localization, and function. For a comprehensive understanding of biology that will propel drug development and biomarker discovery forward, we need to be able to measure proteoforms routinely. In this ep…
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Special Feature - Pursuing Life Sciences Careers: Insights from Anderson MBA Students
50:07
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To learn more about BCLA’s events and consulting visit https://www.bc-la.org/ To learn more about UCLA Anderson School of Management visit https://www.anderson.ucla.edu/ Follow our Instagram @insidebiotech for updates about episodes and upcoming guests! To learn more about BCLA’s events and consulting visit our website. Follow BCLA on LinkedIn…
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Scientific marketing in the century of the biotech revolution
32:37
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Most scientists start their education and careers with a vision of working in the lab to discover great things and drive innovation. However, we don’t all end up loving the actual lab work portion of science. What non-lab career options exist to utilize molecular biology knowledge and skills? Well, according to our guest, Jason Amsbaugh, Founder an…
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As part of the non-sponsored sporadic "B-sides" series*, Ben and Ben sit down and talk with Dr. Matt Padula, University of Technology Sydney. (* this series is where we put guests we want to talk to but who do not fit within any sponsored series, but is still proteomics.... mostly)
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Exploring Neuroscience, Psychiatry, & Rare Diseases, Bruce Leuchter, President & CEO, Neurvati
51:22
51:22
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Synopsis: In this episode of Biotech 2050, host Alok Tayi, CEO and co-founder of Vibe Bio, speaks with Dr. Bruce Leuchter, President and CEO of Neurvati Neuroscience. They discuss capital markets, neurology, psychiatry, and Neurvati's work in ultra-rare diseases. Dr. Leuchter shares his journey from clinical training to leadership at Neurvati. The …
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Episode 39: Spatial proteomics at Pixelgen
46:47
46:47
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Tune in to hear all about Pixelgen Technologies - creators of a novel technologyfor doing single-cell spatial proteomics. We chat about how this fascinating technology works, what you can do with the dataand why they chose to develop their analysis suite as an open-source nf-core pipeline. Links: Software: nf-core/pixelator pipeline Pixelator Pytho…
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Transformative Oncology Innovations, Ken Keller, President & CEO, Daiichi Sankyo, Inc.
28:18
28:18
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Synopsis: In this episode of BioTech 2050, Ken Keller, President and CEO of Daiichi Sankyo, Inc. provides an in-depth look into the company's transformation from a cardiovascular-focused organization to a leader in oncology. He discusses the groundbreaking advancements in antibody-drug conjugates (ADCs), particularly highlighting the success of the…
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EP 138: Personalised medicine using microbiome models with Dr. Almut Heinken
40:22
40:22
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0:00 Introduction 1:45 Almut’s research experience, including two recent publications on genome-scale metabolic reconstruction human microorganisms Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple…
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AI might be the biggest buzz word of the decade, but the buzz is warranted in terms of its practical potential in biological research. In this episode of Translating Proteomics, Parag and Andreas discuss some of the early wins for AI in biology, practical ways AI can be applied to biology research in the near term, challenges in that application, a…
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Hiding in plain sight: The importance of a SOREMP on PSG
49:43
49:43
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Despite having more treatment options than ever before, narcolepsy remains significantly underdiagnosed. Is there a potential clue on the polysomnogram (PSG) that we are overlooking? Dr. Alyssa Cairns and her team are exploring the biophysiological phenotypes of sleep disorders, specifically central disorders of hypersomnolence. She discussed how s…
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As part of the non-sponsored sporadic "B-sides" series*, Ben and Ben sit down and talk with Dr. Mak Saito, Woods Hole Oceanographic Institution. Music: "Olympic Fog" and "Atlantis Snowfall" from The Abyss EP by Deep Six (available on all major streaming services and bandcamp). (* this series is where we put guests we want to talk to but who do not …
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EP 137: Mavis Machirori on promoting equity, diversity, and social justice in genomics research
41:40
41:40
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0:00 Intro 1:30 Mavis’ career arc, from starting as a midwife to researching medical innovation and technology with an emphasis on advocacy and equity 7:00 Systemic issues that are easily overlooked in medical research and advancements Webinar: Participant Diversity: Increasing the Impact of Biomedical Research Webinar 10:00 Addressing Eurocentrici…
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Episode 38: Seqera Pipelines & Seqera Containers
37:22
37:22
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Evan Floden (CEO and co-founder of Seqera) joins Phil Ewels (Product Manager for OSS at Seqera) to talk about two of the big announcements at the recent Nextflow Summit Boston 2024 - Seqera Pipelines and Seqera Containers.We dive into what these two new community offerings are, why we built them and how they work. Links: https://seqera.io/pipelines…
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Strategic Leadership and Autoimmune Breakthroughs, Praveen Tipimeni, CEO
34:03
34:03
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Synopsis: In this episode of Biotech2050, Praveen Tipirneni, CEO of Morphic Therapeutics, shares insights on Morphic’s strategic IPO, the rising interest in autoimmune treatments, the journey of their alpha 4 beta 7 program, and maintaining a conservative yet opportunistic approach in biotech. He also discusses the importance of building a strong t…
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EP 136: Developments in ring chromosome 20 research and advocacy with Allison Watson
40:57
40:57
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0:00 Introduction 2:00 Allison’s personal journey to researching epilepsy and ring chromosome 20 syndrome 4:00 Biggest challenges families face with ring chromosome 20 syndrome 11:00 Incidence and prevalence of r(20) syndrome, and how we can improve data reliability 21:00 Applying next generation sequencing to r(20) syndrome gene research 29:00 Eng…
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Why the Dogma around Biology's Central Dogma Is Wrong
17:37
17:37
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From high school biology on up, we're taught the central dogma of biology - that biological information flows from DNA to RNA to proteins. This representation of the central dogma is, however, very much a simplification of its original formulation by Francis Crick and over-applying it can lead us down spurious paths and faulty conclusions. In this …
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The Philips consent decree and the path forward
53:34
53:34
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After nearly three years, the Department of Justice and the Food and Drug Administration have finally agreed to the terms of a consent decree with Philips. It states that Philips Respironics cannot manufacture or distribute new sleep and respiratory care devices in the U.S. market until certain criteria are met, unless the devices are classified by…
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Ep 42 - B-sides - Drs. Leanne Wybenga-Groot and Brett Phinney
1:15:00
1:15:00
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As part of the non-sponsored sporadic "B-sides" series*, Ben and Ben sit down and talk with Drs. Leanne Wybenga-Groot, SPARC SickKids, and Brett Phinney, University of California, Davis. (* this series is where we put guests we want to talk to but who do not fit within any sponsored series, but is still proteomics.... mostly.)…
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EP 135: Integration of newborn sequencing programs into healthcare systems with Dr. Ingrid Holm
41:16
41:16
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0:00 Introduction 1:30 Ingrid’s initial interests in genetics, paediatrics, and newborn screening 2:45 How the original BabySeq project, a pioneering newborn sequencing program got started, how it’s going, and the launch of BabySeq2 8:45 Lessons from BabySeq1 and goals for BabySeq2 10:30 Potential societal and long-term considerations for those inv…
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Innovative Approaches to Cancer Therapies, Robert Ang, President and CEO
30:09
30:09
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Synopsis: In this episode of BioTech 2050, Robert Ang, CEO of Vor Bio, shares insights on the current state of cancer therapies and next-gen modalities. He discusses Vor Bio's work on shielded stem cell transplants and CAR T-cell therapies targeting hematologic malignancies like AML and MDS. Robert also talks about his experience serving on boards …
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While the end product is quite different, brewing beer is not all that different than many other bioproduction processes used in the lab and industry. Both require skills, experience, and the right QC/QA methods to control and monitor the starting materials and the entire process, all the way to that bottle of suds you might be thirsty for. Steve a…
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Episode 37: The nf-core / EuroFAANG pre-print
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Join us as we discuss the brand new @nf-core / EuroFaang pre-print! 🔥 We chat to some of the key authors, covering the background to the paper, the main messages and how EuroFAANG and nf-core have collaborated. 🧬 👩🏻🔬
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EP 134: Prenatal genetic testing and the future of AI in genetic counselling with Kira Dineen, host of DNA Today
40:44
40:44
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0:00 Introduction 1:00 The backstory of how Kira first started DNA Today in 2012, when she was still in high school! 3:30 Some of Kira’s favourite topics she has discussed on DNA Today, including the legacy of Henrietta Lacks, and the story of a Glee actress with down syndrome 10:00 Kira’s best practices for podcasting, from over 10 years of experi…
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Protein biomarkers are proteins measured as indicators of biological processes. People often hope biomarkers will take the form of elevated or decreased amounts of single proteins, but few single protein measurements provide specific and sensitive indications of biological processes. In this episode of Translating Proteomics, Parag and Andreas disc…
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Tech-Biotech Convergence, Growth, and Global Lessons, Vik Bajaj, Co-founder and CEO
31:05
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Synopsis: In this episode of Biotech2050, Vik Bajaj, Co-founder and CEO of Foresite Labs, delves into the convergence of tech and biotech, hyper-growth phases in biotech companies, changes in finance and capital markets, and lessons from global healthcare systems, particularly the UK. He highlights the transformative potential of technology in biot…
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The world of sleep medicine has had several large recent disruptions with COVID-19 and the Philips Respironics recall. These haven’t been the only ones. If we look back almost a decade, sleep medicine was disrupted by the SERVE-HF results and field safety notice for ResMed ASV devices. Another trial was conducted around the same time as SERVE-HF bu…
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Ep 41 - B-sides - Bill Lane and John Neveu
1:09:22
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As part of the non-sponsored sporadic "B-sides" series*, Ben and Ben sit down and talk with Bill Lane, retired (former director of the Harvard Mass Spectrometry and Proteomics Resource Laboratory) and musician, and John Neveu, President of ESI Source Solutions. (* this series is where we put guests we want to talk to but who do not fit within any s…
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Advancing and Revolutionizing Sickle Cell Treatment, Ted Love, Chair and BOD
27:00
27:00
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Synopsis: In this episode of Biotech2050, Dr. Ted Love, former CEO of Global Blood Therapeutics and Current Chairman of BIO, shares insights on sickle cell breakthroughs, transitioning from academia to research, navigating a tight funding environment, and protecting an innovative ecosystem to benefit patients.Biography:Dr. Ted Love is the chair of …
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EP 133: Insights into pharmacogenomics and increasing diversity in genomics research with Dr. Emma Magavern
39:17
39:17
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0:00 Introduction 2:00 The value of an English Literature degree in designing and analysing research studies in medicine 3:45 Emma’s entrance to pharmacogenomics and her transition from practising physician to genetics research 6:00 How the East London Genes and Health program is increasing representation of diverse populations, namely South Asians…
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Episode 36: The Nextflow Ambassadors Program
24:08
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Join us in this episode of the Channels podcast for a closer look at the Nextflow Ambassadors Program. Marcel Ribeiro-Dantas and Geraldine Van der Auwera discuss the origins of the program, recent highlights and next steps, including the open call for new Ambassadors, which will close June 14. Relevant links: Call for applications: https://www.next…
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EP 132: From mammoths to genome editing, trailblazing genetics with Dr. George Church
47:41
47:41
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0:00 Introduction 1:00 George’s upcoming big projects, including developing full recycling, renewing energy, creating bioweather maps, and harnessing citizen science 6:45 Progress in engineering viral resistance in humans, including thoughts from pre- and post- pandemic 11:00 A swapped genetic code that prevents viral infections and gene transfer b…
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It's no surprise that biological systems change dramatically over space and time, but we often ignore these dynamics when comparing biological samples. In the latest episode of Translating Proteomics, Parag and Andreas discuss why it's essential to take space and time into account and envision ways we can design experiments that explicitly incorpor…
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We know that there are a billion people in the world with undiagnosed obstructive sleep apnea (OSA) and that it simply isn’t practical to have every person undergo a sleep study. Are there other methods that might be more efficient identifying those at the highest risk of OSA? Dr. Laura Castillo is a chemist who has studied biological matrices to i…
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