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Weekly podcasts covering concepts key to critical appraisal. Each episode explores an area of critical appraisal relating to a recent publications. The podcast supports the full Critical Appraisal Lowdown course which is available at www.CriticalAppraisalLowdown.co.uk All papers contained within the episodes are available at The Resus Room podcast.
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JAMA editors and authors explain the methods underlying clinical research to help students, trainees, and health professionals use the published medical literature to make evidence-based decisions for patients. JAMAevidence is an evidence-based medicine (EBM) resource created and maintained by the JAMA Network to promote the use of EBM to improve patient care.
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Official podcast feed of MDedge Psychiatry, part of the Medscape Professional Network. Episodes include interviews with leaders in psychiatry and psychology, masterclass lectures, and clinical perspective. Interviews are hosted by Dr. Lorenzo Norris, MD, Clinical Correlaction featuers Dr. Renee Kohanski, MD, and lecturers are chosen by MDedge Psychiatry. The information in this podcast is provided for informational and educational purposes only.
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Interviews with authors of Rational Clinical Examination systematic reviews in JAMA about the accuracy of the medical history, physical examination, and laboratory testing for the diagnosis of common medical conditions. JAMAevidence is an evidence-based medicine (EBM) resource created and maintained by JAMA Network to promote the use of EBM to improve patient care.
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Join Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, as they interview experts on the hottest topics in healthcare ranging from COVID-19 to social determinants of health to bringing humanity back to medicine.
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Interviews with authors of Care at the Close of Life reviews in JAMA about management issues in end of life and palliative care. JAMAevidence is an evidence-based medicine (EBM) resource created and maintained by the JAMA Network to promote the use of EBM to improve patient care.
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Evidence-Based Practitioners and Evidence-Based Care With Dr Wilson
14:52
14:52
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Mark C. Wilson, MD, MPH, University of Iowa, Carver College of Medicine discusses Evidence-Based Practitioners and Evidence-Based Care with Gordon H. Guyatt, MD, MSc, McMaster University. Related Content:
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Does This Patient Have Alcohol Use Disorder? With Dr Evan Wood
20:07
20:07
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Evan Wood, MD, PhD, University of British Columbia Faculty of Medicine, discusses Does This Patient Have Alcohol Use Disorder? The Rational Clinical Examination Systematic Review with JAMA Associate Editor David L. Simel, MD, MHS. Related Content: Does This Patient Have Alcohol Use Disorder? Pharmacotherapy for Alcohol Use Disorder Treatment of Alc…
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Mark C. Wilson MD, MPH, University of Iowa, discusses Teachers’ Guides to the Users’ Guides with Gordon H. Guyatt, MD, MSc, McMaster University. Related Content: Evidence vs Consensus in Clinical Practice Guidelines How to Interpret and Use a Clinical Practice Guideline or Recommendation
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1
Clinical Diagnosis of Dislocated Hips in Newborns
12:18
12:18
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12:18
Dislocated hips in newborns can lead to complex surgery, interruption to family life, and premature osteoarthritis. Daniel Perry, MBChb(Hons), PhD, of Alder Hey Children's Hospital, University of Liverpool, discusses the clinical diagnosis of dislocated hips in newborns with JAMA Associate Editor David Simel, MD, MHS. Related Content: Does This Inf…
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Does This Child With High Blood Pressure Have Secondary Hypertension? With Dr Nugent
19:33
19:33
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19:33
JAMA Associate Editor David L. Simel, MD, MHS, discusses Does This Child With High Blood Pressure Have Secondary Hypertension? with James T. Nugent, MD, MPH. Related Content: Does This Child With High Blood Pressure Have Secondary Hypertension?
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1
Wisdom From a Scottish GP: The Lost Art of Convalescence
30:55
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30:55
The final Medicine and the Machine podcast guest, physician and author Gavin Francis, shares his approach to keeping his occupation rewarding and satisfying. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. To…
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1
His Rare Disease's Cure Was Sitting on the Pharmacy Shelf
37:28
37:28
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He's alive thanks to a repurposed drug. Now his dream is to find cures for millions of people from among drugs we already have. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Tra…
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Assessing the Strength of Recommendations: The GRADE Approach With Dr Vandvik
15:55
15:55
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Gordon H. Guyatt, MD, MSc, discusses Assessing the Strength of Recommendations: The GRADE Approach with Per Olav Vandvik, MD, PhD. Related Content: How to Interpret and Use a Clinical Practice Guideline or Recommendation
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1
Physicians: Shape Your AI Future or Someone Else Will
27:54
27:54
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Dr Eric Topol discusses the present and future of AI in medicine with historian and futurist Dr Adam Rodman. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science …
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Left-Digit Bias and Other Random Acts of Medicine
39:38
39:38
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A new book reveals how chance can change the course of a person's health, life, and death. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Profess…
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Understanding and Applying the Results of a Systematic Review With Dr Murad
16:27
16:27
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Host Gordon Guyatt, MD, MSc, discusses Understanding and Applying the Results of a Systematic Review with M. Hassan Murad, MD, MPH. Related Content: How to Read a Systematic Review and Meta-analysis and Apply the Results to Patient Care Acute Treatments for Episodic Migraine in Adults
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1
How the Modern ICU Was Galvanized By a Polio Epidemic
34:36
34:36
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34:36
The medical and dental students who kept polio patients alive by hand-ventilating them around the clock are among the cast of characters in this incredible story. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric …
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Bob Wachter's Viral Tweet and Thoughts on AI in Medicine
38:46
38:46
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38:46
The gig was up, but when he finally got COVID, it was pretty far down on his ER problem list. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Prof…
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Fixed-Effects and Random-Effects Models With Dr Murad
20:30
20:30
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Gordon H. Guyatt, MD, MSc, discusses Fixed-Effects and Random-Effects Models with M. Hassan Murad, MD. Related Content: Random-Effects Meta-analysis
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1
AI Comes to Medicine: This Time, It's Serious
38:14
38:14
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38:14
Information pollution is just the beginning. We're in for an uncomfortable ride. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Mole…
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1
Tragedy, Hope, and a Medical Mystery: 'The Covenant of Water'
43:08
43:08
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Dr Eric Topol and Dr Robert Harrington interview Dr Abraham Verghese about his fiction writing methods and Oprah's enthusiasm for his latest novel. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, D…
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Does This Patient With Acute Infectious Conjunctivitis Have a Bacterial Infection? With Dr Johnson
19:43
19:43
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David L. Simel, MD, discusses Does This Patient With Acute Infectious Conjunctivitis Have a Bacterial Infection? with Davin Johnson, MD. Related Content: Does This Patient With Acute Infectious Conjunctivitis Have a Bacterial Infection?
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There's No Place Like Home for Hospital Care
27:36
27:36
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Dr Helen Ouyang on why she writes so much about the hospital-at-home movement: It's the future, one way or another. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational S…
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1
Rogue Faculty and Academic Freedom in the Age of Misinformation
35:52
35:52
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Should our nation's academic institutions rein in faculty who amplify conspiracy theories and spread potentially harmful falsehoods? This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripp…
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How AI and Chatbots Can Make Us Healers Again
32:40
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32:40
ChatGPT and large language models offer physicians the chance to do what they went to medical school for: connect with patients and help them regain their health. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric …
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Adjusted Analyses in Studies Addressing Therapy and Harm With Dr Agoritsas
17:22
17:22
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Gordon H. Guyatt, MD, MSc, discusses Adjusted Analyses in Studies Addressing Therapy and Harm with Thomas Agoritsas, MD, PhD. Related Content: Adjusted Analyses in Studies Addressing Therapy and Harm
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Hannah Fry: The Mathematician Who Knows Uncertainty Is Unavoidable
37:58
37:58
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Eric Topol and Abraham Verghese chat with the UK's professor Hannah Fry about taking risks and asking the right questions. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translat…
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Two-way masking is pretty effective, but it's not sustainable. Environmental engineer and viral transmission expert Dr Linsey Marr reveals how we can fight COVID by tackling our contaminated air. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.…
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Gordon Guyatt, MD, MSc, discusses Spectrum Bias with Reem A. Mustafa. MD, MPH, PhD.
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How We Can Err if We Rely on Randomized Controlled Trials
40:51
40:51
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Dr Trish Greenhalgh explains how we miss the boat when we discount real-world evidence in favor of randomized trial evidence. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Trans…
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How We Create--Then Blame--A Viral Underclass
30:08
30:08
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Stephen Thrasher discusses his new book, The Viral Underclass: The Human Toll When Inequality and Disease Collide. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Sc…
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Discrimination and Calibration of Clinical Prediction Models With Dr Alba
16:46
16:46
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Gordon Guyatt, MD, MSc, discusses Discrimination and Calibration of Clinical Prediction Models with Ana Carolina Alba, MD, PhD. Related Content: Discrimination and Calibration of Clinical Prediction Models With Dr Alba Read Transcript
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The Golden Age of Virology? An Expert's Take on Polio, Monkeypox, and COVID-19
52:55
52:55
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Virologist Jeremy Kamil shares his relatively upbeat perspective on the viral threats we face today. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institut…
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1
We Are Failing to Use What We've Learned About COVID
39:17
39:17
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39:17
Another COVID-19 variant is inevitable because we aren't doing anything to stop it, says UK operational researcher Christina Pagel. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps…
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1
Hidden in Plain Sight: If AI Can Detect Race, What About Bias?
36:24
36:24
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36:24
An AI model accurately predicts a person's race from a chest radiograph with stunning accuracy. Here's why it matters, and how it poses research questions about bias in medicine. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/publ…
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How to Interpret and Use a Clinical Practice Guideline or Recommendation With Dr Gordon Guyatt and Dr Brignardello-Petersen
32:26
32:26
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Host Robert M. Golub, MD, discusses How to Interpret and Use a Clinical Practice Guideline or Recommendation with Gordon H. Guyatt, MD, MSc, and Romina Brignardello-Petersen, DDS, MSc, PhD.
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Abraham Verghese talks with Stanford's Dr Linda Geng, who is studying the puzzling and poorly understood postviral phenomenon known as long COVID. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Abraham Verghese, MD,…
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It's Not All Fun and Games: How DeepMind Unlocks Medicine's Secrets
44:19
44:19
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Eric Topol speaks with DeepMind CEO Demis Hassabis about harnessing the potential of AI in health and medicine. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Scien…
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Measuring Agreement Beyond Chance With Dr Thomas McGinn
15:00
15:00
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Gordon Guyatt, MD, discusses Measuring Agreement Beyond Chance with Thomas McGinn, MD, MPH. Related Content: Does This Patient Have Infectious Mononucleosis? The Rational Clinical Examination Systematic Review
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Pain is central to every specialty, and we all played a part in the opioid crisis, says Dr Haider Warraich, author of The Song of Our Scars: The Untold Story of Pain. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine E…
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Animal Reservoirs, Immunocompromised Hosts: COVID Dangers Ahead
34:00
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Stanford's Benjamin Pinsky on the potential for even more transmissible and pathogenic versions of the SARS-CoV-2 virus to arise. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps T…
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Why we should be shifting into high gear on treatments for long COVID and a pan-beta-coronavirus vaccine. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Ins…
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1
The Medical Model Doesn't Work for Mental Health
39:03
39:03
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Former NIMH Director Tom Insel explains how the medical model has failed the field of psychiatry. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; …
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Epidemiologist-engineer Michael Mina thinks diagnostics belong in the hands of the people. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. Topol, MD, Director, Scripps Translational Science Institute; Profess…
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1
Correlation and Regression With Dr Jaeschke
15:48
15:48
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Gordon H. Guyatt, MD, MSc, discusses
…
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'Historic Botched Job': The Narrative Mechanics of Failed COVID Communication From CDC and Elsewhere
34:07
34:07
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Randy Olson on what science can learn from Hollywood about communicating with the masses. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/viewarticle/969151 Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of …
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1
COVID Vaccines for the Under 5's: The 'Finish Line' We Need
37:41
37:41
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'Your Local Epidemiologist' Katelyn Jetelina translates the COVID science for millions. This podcast is intended for US healthcare professionals only. Eric J. Topol, MD; Abraham Verghese, MD; Katelyn K. Jetelina, PhD, MPH Your Local Epidemiologist (YLE) Newsletter: https://yourlocalepidemiologist.substack.com/about You may also like: Medscape's Chi…
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1
Dr. Glaucomflecken on Why We Can All Use a Laugh Right Now
32:33
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Two bouts with cancer and a cardiac arrest at age 35 haven't stopped this ophthalmologist-comedian from becoming a social media phenomenon for hilariously poking fun at medicine and himself. This podcast is intended for US health professionals only. Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicin…
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1
Does This Adult Patient Have Hypertension? Interview With Dr Anthony Joseph Viera
12:38
12:38
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David Simel, MD, discusses Does This Patient Have Hypertension? with Anthony J. Viera, MD, MPH. Related Content: Does This Adult Patient Have Hypertension? Interview With Dr Anthony Joseph Viera USPSTF Recommendation: Screening for Hypertension in Adults USPSTF Review: Screening for Hypertension in Adults…
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1
2021: Where We Succeeded, Where We Failed in Pandemic Year Two
27:42
27:42
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Eric Topol and Abraham Verghese reflect on 2021's extraordinary podcast guests, and how we excelled in science and healthcare but were tripped up by the vagaries of human behavior. This podcast is intended for US healthcare professionals only. For more episodes of Medicine and the Machine https://www.medscape.com/features/public/machine Eric J. Top…
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Former White House COVID Advisor: We Can All Safely Experience Joy This Holiday Season
43:40
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Andy Slavitt believes we've made real progress, despite overselling vaccines and the public's dismay with rapidly changing science. This podcast is intended for US healthcare professionals only. Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California…
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1
Dr Kimberly Manning on Twitter Teaching, Vaccine Deliberation, and Her Own Secret Sauce
32:26
32:26
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Her message to academia: If you really want diversity, equity, and inclusion in medicine, put your money where your mouth is. This podcast is intended for US healthcare professionals only. Eric J. Topol, MD, Director, Scripps Translational Science Institute; Professor of Molecular Medicine, The Scripps Research Institute, La Jolla, California; Edit…
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Gordon Guyatt, MD, discusses economic analysis with Paul Moayyedi, PhD
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1
How Pediatrician Rachel Pearson Brings Along Vaccine-Hesitant Parents
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Talking about how being vaccinated will let school-aged kids get back to normal life is paramount. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/viewarticle/960620 Eric J. Topol, MD, Director, Scripps Translational Science Institute; Prof…
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Dr Ebony Hilton Wants to Talk Herself Out of a Job
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If you want her to stop talking about racial and gender disparities in healthcare, fix the system. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/viewarticle/960379 Eric J. Topol, MD, Director, Scripps Translational Science Institute; Prof…
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