This podcast provides you with education, tips, and useful advice. Whether it is you or a loved one, whether you are in treatment or beyond it, we strive to include everyone who has been touched by cancer. Our goal is singular: To help you. We frame it around cancer, but really, anyone can benefit. We are two naturopathic physicians with extensive experience in natural medicine and integrative oncology. Leah is the "cancer insider." Tina is the science-y one and enjoys teaching you the "why" ...
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Oncology On The Go is a biweekly podcast that talks to authors and experts to thoroughly examine featured articles in the journal ONCOLOGY. Each episode, you'll hear from one of the authors of our featured article to summarize the important takeaways from that piece. Then, an outside expert will give their perspective on the details of that article. As the home of the journal ONCOLOGY, CancerNetwork offers different perspectives on oncology/hematology through review articles, news, podcasts, ...
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Welcome to Integrative Oncology Talk! Where we discuss the latest science and opinions from leading voices in integrative oncology. Integrative oncology utilizes complementary therapies and lifestyle strategies to help those affected by cancer, using personalized approaches and evidence based recommendations. This podcast is hosted by Dr. Santosh Rao, a medical oncologist and integrative oncologist. Dr. Judith Lacey, a supportive care and integrative oncology physician. And Leigh Leibel (pro ...
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Exploring all things genetics. Dr Patrick Short, University of Cambridge alumnus and CEO of Sano Genetics, analyses the science, interviews the experts, and discusses the latest findings and breakthroughs in genetic research. To find out more about Sano Genetics and its mission to accelerate the future of precision medicine visit: www.sanogenetics.com
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Dr. Alex Hill, Pelvic Health & Oncology Physical Therapist
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Pelvic health is often overlooked, especially in cancer care. Dr. Alex Hill shares invaluable insights and practical strategies for addressing common issues like urinary incontinence, sexual dysfunction, and constipation. Join us in this enlightening discussion about the tools of the trade, types of pelvic floor exercises (Spoiler: It's not just Ke…
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S1 Ep107: Applying Novel Radiotherapy Technology for Brain Tumors and Other Cancers
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17:51
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In a conversation with CancerNetwork® at John Theurer Cancer Center, Timothy Chen, MD, highlighted various novel treatment strategies that have impacted his care of patients with brain tumors and other types of cancer. Chen, a board-certified radiation oncologist and medical director of the Central Nervous System Program at Jersey Shore University …
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EP 132: From mammoths to genome editing, trailblazing genetics with Dr. George Church
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47:41
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0:00 Introduction 1:00 George’s upcoming big projects, including developing full recycling, renewing energy, creating bioweather maps, and harnessing citizen science 6:45 Progress in engineering viral resistance in humans, including thoughts from pre- and post- pandemic 11:00 A swapped genetic code that prevents viral infections and gene transfer b…
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S1 Ep106: Moving The Needle in Lung Cancer Management With Robotic-Assisted Surgery
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The robotic-assisted biopsy platform Ion is a “game-changer” for patients with lung cancer, as it provides a quicker, less invasive surgical method for conducting a lung biopsy, according to Richard Lazzaro, MD. In a conversation with CancerNetwork, Lazzaro, the chief of Thoracic Surgery at the Southern Region of RWJBarnabas Health, spoke about his…
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EP 131: The potential of somatic genomics in drug discovery and development with Jake Rubens
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44:57
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0:00 Intro 0:40 Jake’s experiences as a serial entrepreneur starting five companies with a basis in genomic science 5:30 Opportunities for research and drug development in the realm of somatic science 9:20 Somatic evolution and how it provides valuable insights into disease mechanisms 12:30 Advantages and disadvantages of studying germline genome-w…
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S1 Ep105: Surgeons Talk Key Treatment and Institutional Advances Across Oncology Care
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During the 2024 Society of Surgical Oncology Annual Meeting (SSO), CancerNetwork® spoke with a variety of surgical oncology experts regarding the topline data they presented. Each conversation also expanded upon how these results can be implemented into the clinical space and the next research steps. First, Adrienne Bruce Shannon, MD, a complex gen…
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EP 130: Quarterly insights into noncoding variants and GWAS with Dr. Veera Rajagopal
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51:56
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Show Notes: 0:00 Introduction 1:20 How polydactyl mutations can inform research on non-coding variant mechanisms The importance of low-affinity binding between transcription factors and targets How these lessons can help us improve our understanding of drug and target discovery See Veera’s January round-up for more information: https://www.gwasstor…
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S1 Ep104: Finding Ways to Break the Mold in GU Oncology
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35:47
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As part of Breaking Barriers: Women in Oncology, Maha H. Hussain, MD, and Sarah E. Fenton, MD, PhD, spoke with CancerNetwork® about developments in their careers and the evolution of research in the genitourinary oncology (GU) field. Additionally, they discussed their personal experiences in the field, which ranged from applying key pieces of advic…
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EP 129: Patient advocacy for genetic ALS and FTD with Jean Swidler, Executive Director of End the Legacy
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38:44
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0:00 Introduction 0:45 Jean’s personal experiences with family members with genetic ALS 10:00 Jean’s thoughts on the barriers and facilitators to providing treatment for those with genetic ALS 13:20 Insights into C9orf72, a common genetic determinant of ALS, and how it can also be associated with FTD 16:10 Jean’s experiences as an active advocate f…
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Prebiotics vs. Probiotics: Supplements 101
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Prebiotics feed our probiotics. So which is more important? Should you supplement with prebiotics? In this episode Tina and Leah discuss the different types of prebiotics and where to find them. They also talk about ketogenic diets, when a probiotic may interfere with treatment, and the hidden benefits in potatoes, rice and pasta! Here are the seve…
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S1 Ep103: Achieving Health Equity in Lung Cancer Surgery
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In a conversation with CancerNetwork®, Rian M. Hasson Charles, MD, MPH, FACS, spoke about her career in thoracic surgery and her visions for increasing equitable care in the field as part of a new, first-of-its-kind role at Brigham and Women’s Hospital. She will serve as the inaugural vice chair for Diversity, Equity, and Inclusion (DEI) in the Dep…
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EP 128: Parkinson’s disease and precision medicine with Drs. James Beck and Ignacio Mata
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0:00 Introduction 1:05 Insights into the PD GENEration’s (a programme from the Parkinson's Foundation) milestones and progress points for the upcoming year 3:30 The shifting attitudes and perspectives of neurologists and healthcare workers at the PD GENEration 5:50 Insights into Nacho’s work with the genetics of Parkinson’s disease 10:20 Barriers a…
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S1 Ep102: Updated ASCO Guidelines for Optimal Small Cell Lung Cancer Management
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In a conversation with CancerNetwork®, Gregory Peter Kalemkerian, MD, spoke about the publication of updated guidelines for managing small cell lung cancer (SCLC) with systemic therapy, which was developed by the American Society of Clinical Oncology (ASCO) in collaboration with Ontario Health (Cancer Care Ontario).1 Kalemkerian, a clinical profess…
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EP 127: Insights into precision medicine, fatty liver disease, and minimally invasive diagnostic tools with Dr. Mazen Noureddin
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0:00 Intro 0:25 Mazen’s lifelong commitment to furthering the field of precision medicine in liver disease research, fueled by a personal connection of his grandmother developing MASH cirrhosis 2:30 Breakthroughs in the field of metabolic dysfunction-associated steatotic liver disease (MASLD) since the beginning of Mazen’s career 5:30 The potential…
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Interview with Alison Tierney, Cancer Dietitian
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Discover valuable insights on nutrition, self-advocacy, and overcoming challenges in this heartfelt interview with Alison Tierney, MS, RD, CD, CSO, a cancer dietitian and #cancerinsider. Tina and Leah lead an engaging conversation on navigating treatment and beyond. Whether you're a beginner in healthy eating or a seasoned health enthusiast, Alison…
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S1 Ep101: Creating a First-of-Its-Kind Integrative Oncology Program at City of Hope
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CancerNetwork® collaborated with OncLive® to speak with Edward S. Kim, MD, MBA, and Richard T. Lee, MD, about ongoing initiatives to expand integrative oncology for patients with cancer at City of Hope. Kim is the physician-in-chief and senior vice president at City of Hope Orange County as well as the Construction Industries Alliance City of Hope …
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EP 126: Patient-led research for ultra-rare disease drug development with Julia Taravella, Executive Director of Rare Trait Hope Fund
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0:00 Introduction 0:25 Julia’s personal experience with ultra-rare diseases within her family 10:25 The importance of increasing accessibility to genetic testing across populations to learn more about ultra-rare diseases 14:00 The origin story of Rare Trait Hope Fund 23:50 Current research and next steps in developing potential gene therapies for a…
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S1 Ep100: Addressing Rising Cancer Incidence and Burden in Younger Populations
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15:08
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Monique Gary, DO, MSc, FACS spoke with CancerNetwork® about estimated increases in cancer burden across the world and the potential rises in cancer inequities among underserved populations, and discussed mitigating these disparities from an oncology and primary care perspective. Gary, a board-certified breast surgical oncologist and medical directo…
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EP 125: The future of UK Clinical Trial Policy: Innovation, integration, and game-changing legislation with Lord James O’Shaughnessy
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0:00 Introduction 1:25 How Lord O’Shaughnessy became involved in scientific policy making and his path to writing the UK Commercial Clinical Trials Review. 04:05 How Lord O’Shaughnessy pivoted from education to a focus on life sciences 06:38 The biggest challenges Lord O’Shaughnessy faced during his time as Parliamentary Under Secretary for Health …
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Cruciferous vegetables, like broccoli, kale, arugula, cabbage, and radishes, are sometimes called "super foods." But why? How are they good for you? In this episode, Tina and Leah answer these questions and discuss ways crucifers can be part of a healthy diet. They touch on some of the supplements that come from crucifers, too. So, hit play, and yo…
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S1 Ep99: How to Expand Health Equity in Oncology
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In a conversation with CancerNetwork®, Robert A. Winn, MD, spoke about current obstacles in achieving equitable care for patients with cancer and discussed how initiatives from community health centers and federal bodies alike may help increase access to anti-cancer therapy. Winn, director and Lipman Chair in Oncology at Virginia Commonwealth Unive…
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EP 124: How ReCode Therapeutics is pioneering tissue specific delivery of gene therapies for Primary Ciliary Dyskinesia with John Matthews
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0:00 Introduction 01:10 How growing up in Malawi planted the seeds for John’s career in medicine and transition to therapeutic development 04:35 Why John focuses on rare diseases and conditions such as asthma 06:01 What has changed over the last decade in terms of treating and understanding asthma and the progress that genetics has enabled 07:31 Wh…
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S1 Ep98: Diane M. Simeone, MD “Thrilled” To Be UCSD Moores Cancer Center Director
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Starting April 1, 2024, Diane M. Simeone, MD will start her new position as director of the University of California San Diego (UCSD) Health Moores Cancer Center.1 In a conversation with CancerNetwork®, Simeone highlighted her excitement to be working with an institution that she said aligns with her goals and values. During her time as director, s…
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EP 123: The ethics of newborn genome screening: Actionable insights and beyond with Holly Peay, Senior Research Scientist at the Research Triangle Institute
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45:34
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0:00 Introduction 0:50 Holly’s background and career so far 03:30 Complex decision-making and multiple risk factors: Family history, genetics, phenotypes and beyond 07:05 Changes within the last decade to help people make complex, sometimes subjective, healthcare decisions 09:20 Impact on people: The RTI’s mission and the Early Check Study 13:45 Ne…
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Berries are one of the most easily accessible, nutrient-packed plant foods we can eat. You may know that berries are good for you, but do you know what makes them so nutritious? Tina and Leah talk about common and exotic berries and tell you what's inside berries that makes them so awesome! You may even learn a few new plants you didn't know were t…
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S1 Ep97: Expert Perspectives on 2024 ASCO GI Cancers Symposium Trial Updates
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31:22
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After the 2024 Gastrointestinal Cancers Symposium, Jun Gong, MD, and Daneng Li, MD, sat down to discuss the most relevant trial data to have come from the conference. They convened for a live X Space hosted by CancerNetwork®. During the discussion, they covered different trials across the gastrointestinal space, which included those evaluating diff…
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EP 122: Building genome-scale engineered cells for biotechnology with Leslie Mitchell, Co-founder and CEO of Neochromosome
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Summary: 0:00 Introduction 01:01 How Leslie got into the field of synthetic biology and engineering, and her career journey so far 02:45 What Leslie accomplished during her postdoc and recent transformations in the field of genomics 05:57 The impacts of non-coding regions of the genome and the outcome of deletions 08:20 How long it takes to make ch…
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S1 Ep96: Combatting Stigmatization to Increase Lung Cancer Screening Access
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16:06
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In a conversation with CancerNetwork®, Lisa Carter-Bawa PhD, MPH, APRN, ANP-C, FAAN, spoke about factors that may contribute to feelings of stigmatization surrounding a lung cancer diagnosis, which may impact an individual’s decision to undergo screening for potential disease. Specifically, Carter-Bawa, director of the Cancer Prevention Precision C…
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EP 121: Breakthroughs and insights in ALS research with Dr. Michael Benatar
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Summary: 0:00 Introduction 0:50 Reflections from the 34th International Symposium on ALS/MND in Basel 1:50 Michael’s professional journey, initial challenges he encountered, and how the field of neurology has evolved over the years 3:10 An introduction to the ALS landscape, including its presentation, the genes involved, and potential treatment opt…
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Understanding Electrolytes: Supplements 101
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Electrolyte balance is essential for optimal function of all of our systems. This episode covers the electrolytes you should pay close attention to during and after treatment. We're not talking designer drinks or influencer hacks to your biology, just practical knowledge and tips to help you balance your electrolytes. Join Tina and Leah as they tal…
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S1 Ep95: Unraveling Resistance and Heterogeneity in Mantle Cell Lymphoma Management
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Although strides have been made with Bruton tyrosine kinase (BTK) inhibitors and CAR-T cell therapy, relapse and resistance remain significant hurdles in treating patients with mantle cell lymphoma (MCL). The Lymphoma Research Foundation's 2023 MCL Scientific Consortium and Workshop addressed these complexities, aiming to dissect the intricate biol…
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EP 120: Exploring the frontiers of gene therapy and AAVs with Dr. Nicole Paulk, CEO and Founder of Siren Biotechnology
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43:47
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0:00 Introduction to Dr. Nicole Paulk, a pioneer in AAV research and the founder of Siren Biotechnology 0:50 The moments that shaped Nicole’s career path and her passion for gene therapy and AAV research 9:20 Nicole’s academic research career and her transition from academia to the biotech industry 23:00 The story behind the founding of Siren Biote…
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S1 Ep94: SIO/ASCO Guidelines for Integrative Therapies to Manage Anxiety/Depression
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Integrative therapies have been proven to help reduce the adverse effects (AEs) of anxiety and depression in patients with cancer, according to Linda E. Carlson, PhD, RPsych. Carlson, Enbridge Research Chair in Psychosocial Oncology and a professor in the Department of Oncology, Cumming School of Medicine at the University of Calgary, explained how…
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EP 119: Revolutionising drug discovery: how the Pharma Proteomics Project is combining genetic and proteomic data with Chris Whelan
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38:25
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0:00 Introduction 01:00 Chris’ background and career to date 02:10 What is the Enigma Project? 04:48 How is genetics being applied to drug discovery today and how does proteomics fit in? 09:23 When the UKBiobank Pharma Proteomics Project began and how long it took to set up 10:57 54k UK Biobank participants tested - discussion of findings 14:33 The…
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Ginger "root" has been used for thousands of years. Technically a rhizome, not a root, ginger's modern-day claim to fame is its ability to prevent the onset of nausea. Ginger is so reliable and safe that it's been studied to prevent nausea during pregnancy as well as chemo-induced nausea. But that is just the beginning of the benefits of ginger. It…
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S1 Ep93: Jyoti S. Mayadev, MD, on Pembrolizumab/CRT FDA Approval in Cervical Cancer
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In a conversation with CancerNetwork® prior to the FDA approval of pembrolizumab (Keytruda) plus chemoradiotherapy in FIGO stage III to IVA cervical cancer, Jyoti S. Mayadev, MD, spoke about how the regimen’s approval would be a “major step” for the aforementioned population and how she planned to integrate it into her care.1 Mayadev, a board-certi…
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EP 118: The role of genetics in drug discovery and development with Dr. Matt Nelson
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Summary: 0:00 Introduction 5:45 Lessons learned from 15 years at GSK: How has genetics and drug discovery evolved over time? 8:10 Matt’s seminal 2015 paper: Quantifying the impact of human genetic evidence on the probability of success in drug development 11:40 Which types of genetic evidence are the best drivers of success in clinical trials? 13:3…
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S1 Ep92: Managing CDK4/6 Inhibitor, ADC Toxicity in Metastatic Breast Cancer
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In a conversation with CancerNetwork®, Sarah Donahue, MPH, NP, discussed strategies for managing adverse effects (AEs) associated with different drug classes for patients with metastatic breast cancer, ranging from antibody drug conjugates (ADCs) to CDK4/6 inhibitors. With respect to ADCs, Donahue, a nurse practitioner at University of California, …
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EP 117: Wendy Chung: whole genome newborn screening and other big opportunities in genomic medicine.
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Summary: 0:00 Introduction 1:45 Wendy’s early career looking into the genetics of diabetes through mouse models 6:23 A high altitude view: Cutting through hype to spot the next wave of game-changing technology 8:03 The role of policy and communication: how Wendy’s work goes beyond the lab to create real-world impact 11:20 Wendy’s choice to do an MD…
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Joint pain is common, but that doesn't mean you have to suffer! There are so many natural remedies to control and relieve the discomfort. Whether you are preventing joint pain during treatment or you have ongoing arthritis-type pain, Tina & Leah talk about ways to find relief. We even tackle the tough-to-treat joint pain from aromatase inhibitors (…
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S1 Ep91: HER2CLIMB-02 Trial Shows ‘Interesting Data’ in HER2+ Breast Cancer
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In a recent conversation with CancerNetwork®, Sara A. Hurvitz, MD, FACP, senior vice president and director of the Clinical Research Division at Fred Hutch Cancer Center and head of the Division of Hematology and Oncology at the University of Washington Department of Medicine, discussed new treatment options for patients with metastatic HER2-positi…
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EP 116: Genetics and Medicine: Clonal hematopoiesis, genomics in healthcare, and a new discovery in APOL1 kidney disease with Dr. Alex Bick
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0:00 Introduction 4:23 Insights into clonal hematopoiesis from the pioneering Framingham Heart Study 8:30 Linking clonal hematopoiesis to cancer and cardiovascular health 11:22 Interplay of germline and somatic variants in clonal expansion 17:20 How the rate of clonal expansion can provide insights into cancer and cardiovascular risk 19:00 How clon…
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S1 Ep90: Frontline Chemo-Free Regimen Supported in HR+/HER2+ Breast Cancer Therapy
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In a conversation with CancerNetwork®, Amy Tiersten, MD, spoke about how findings from the phase 1/2 ASPIRE trial (NCT03304080) may support anastrozole (Arimidex) plus palbociclib (Ibrance), trastuzumab (Herceptin), and pertuzumab (Perjeta) as a first-line treatment for patients with hormone receptor (HR)–positive, HER2-positive metastatic breast c…
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EP 115: The Biggest Stories of 2023 with Dr. Veera Rajagopal (Part 2)
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In the second instalment of our annual round-up episode, we welcome back Dr. Veera Rajagopal to cover the biggest stories in genetics and precision medicine of the last 12 months. Don’t forget to give the first instalment of our 2023 round-up a listen. Veera is a scientist at Regeneron with an interest in human genetics and drug target discovery in…
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EP 114: The Biggest Stories of 2023 with Dr. Veera Rajagopal (Part 1)
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0:00 Introduction 1:30 Veera’s personal highlights of 2023 Publication in Nature Genetics: Rare coding variants in CHRNB2 reduce the likelihood of smoking, an exome-wide association study identifying rare coding variants in CHRNB2 that may reduce the likelihood of smoking. Designing cover art Genetic links to neural circuits and their role in addic…
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We've all heard that "the dose makes the poison." Nowhere is this a more apt saying than with nutmeg. Hey, don't get us wrong, just a wee bit of nutmeg can help you tolerate some of those holiday food indulgences! Nutmeg is warming, has anti-parasite and pain-relieving properties, and can be used topically for pain relief. Join us as we touch on so…
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S1 Ep89: Expert Discusses Screening Advocacy, AI, and Developments in Breast Cancer
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In a conversation with CancerNetwork®, Rakshanda Rahman, MD, FRCS, FACS, discussed a wide range of surgical therapy strategies and other developments in the breast cancer space, ranging from factors that should be considered for surgical decision-making to the evolution of artificial intelligence (AI) in the field. Rahman, a professor of Breast Sur…
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S1 Ep88: Joleen Hubbard, MD, Highlights The “Exciting Space” Of Metastatic CRC
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In a recent discussion with CancerNetwork®, Joleen Hubbard, MD, research collaborator with Mayo Clinic and deputy director for clinical research at Allina Health Cancer Institute in Minneapolis, Minnesota, discussed new opportunities for patients with colorectal cancer (CRC). In the discussion, Hubbard highlighted the potential of trastuzumab derux…
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EP 113: Harnessing human genetics to discover co-evolved small molecule medicines with Dr. Jason Park, CEO of Empress Therapeutics
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In this episode of The Genetics Podcast, we welcome Dr. Jason, founder and CEO of Empress Therapeutics, a Flagship Pioneering company. Join us as we discuss how human genetics can identify small molecules with therapeutic potential that are already created by our bodies, paving the way for faster discovery of new medicines. Summary: 0:00 Intro 1:20…
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'Tis the season! Pine trees are everywhere! From vitamin C to turpentine (yes, the paint thinner!), pine trees give us a lot to talk about. Listen in as Tina & Leah chat about the uses and cautions of the ubiquitous pine tree in this holiday minisode. And don't forget... hit those 5 stars and send this episode to someone you think would enjoy it! T…
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