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Each episode of AJP Audio brings you an in-depth look at one of the articles featured in that month’s issue of The American Journal of Psychiatry, the official journal of the American Psychiatric Association. Wide-ranging interviews with article authors cover the background, rationale, main findings, and future implications of the research. This podcast is subject to the Terms of Use at ww.psychiatry.org. The views and opinions expressed in this podcast are those of the individual speakers o ...
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Tips for You and Your Child from University of Iowa Hospitals and Clinics Child and Adolescent Psychiatry Clinic. Find transcripts, translations and further resources at https://medicine.uiowa.edu/psychiatry/education/byte-sized-brain-new-podcast-child-and-adolescent-psychiatry-clinic
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A resource for psychiatrists and other medical or behavioral health professionals interested in exploring the neuroscientific basis of psychiatric disorders, psychopharmacology, neuromodulation, and other psychiatric interventions, as well as discussions of pseudoscience, Bayesian reasoning, ethics, the history of psychiatry, and human psychology in general. This podcast is not medical advice. It strives to be science communication. Dr. O'Leary is a skeptical thinker who often questions what ...
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Mindhunting with Forensic Psychiatrist Dr Michael Schirripa
56:11
56:11
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56:11
Send us a Text Message. -- Dr. O’Leary interviews forensic psychiatrist and author Dr. Michael Schirripa about his career as a forensic psychiatrist, the release of his first thriller, Mindhunt, and his podcast Mindhunting. Dr. Shirripa explores how his love of literature influenced his decision to pursue forensic psychiatry and ultimately resulted…
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Psychedelics - A skeptical approach to MDMA aka Ecstasy
31:46
31:46
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Send us a Text Message. - - In the world of psychotropic medication, the question is not just whether it works or not, but whether it works better than a placebo and whether the effect size is clinically significant and the benefits outweigh the risks. In the case of MDMA (aka molly or ecstasy), the effect size for improving post-traumatic stress d…
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July 2024: Association of Occupational Dysfunction and Hospital Admissions With Different Polygenic Profiles in Bipolar Disorder
31:20
31:20
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31:20
Dr. Lina Jonsson (Sahlgrenska Academy at University of Gothenburg, Sweden) joins AJP Audio to discuss the association of occupational dysfunction and hospital admissions with polygenic profiles in patients with bipolar disorder. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the July issue of AJP. 00:45 Jonsson interview 04:35 …
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The Narrative Fallacy in Psychological and Psychiatric Clinical Practice with Dr. Alexey Tolchinsky, PsyD
55:14
55:14
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55:14
Send us a Text Message. The Narrative Fallacy describes our tendency to find meaning, connections, and causal relationships where they do not necessarily exist. In this episode, Dr. O'Leary had the pleasure of interviewing Dr. Alexey Tolchinsky. He recently published a paper called “Narrative fallacy and other limitations of psychodynamic case form…
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Psychometrics - The Dangers of Rating Scales and Screeners
31:45
31:45
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31:45
Send us a Text Message. Dr. O'Leary discusses a variety of concerns that all clinicians should have in mind when using psychometrics. In the end, he hopes you come away with some level of agreement with the statement: “Our primary concern should not be with the quantity of data, but with the quality of the data.” Statistics are conceptual machines …
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Send us a Text Message. In this episode, Dr. O'Leary discusses a word that he has struggled to understand since medical school. The word is aphasia. The root “phasia” comes from the Greek phanai which means “to speak.” When aphasia is used medically, it refers to an inability to speak, although not always. More generally it is often used to mean a …
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June 2024: Long-Term Course of Remission and Recovery in Psychotic Disorders
29:23
29:23
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Ms. Sara Tramazzo (Stony Brook University) joins AJP Audio to discuss the long-term outlook for patients with schizophrenia spectrum disorders and other psychotic disorders over the course of 25 years. Afterwards, Dr. Ned Kalin joins to discuss the rest of the June issue of AJP. 00:50 Tramazzo interview 01:55 Lower levels of recovery and remission …
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May 2024: Predictors of Substance Use Initiation by Early Adolescence
36:45
36:45
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Dr. ReJoyce Green (Medical University of South Carolina, Charleston, SC) joins AJP Audio to discuss predictors of substance use initiation in a large cohort of early adolescents. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin speaks with AJP Deputy Editor Dr. Kathleen Brady about the May issue of AJP, a special issue guest edited by Dr. Brady focusi…
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Send us a Text Message. I did not until recently even consider the cerebellum when thinking about psychiatric conditions, but the more I read, the more I wonder why the cerebellum is not considered a potential important player in nearly every psychiatric disorder. Although it can be said that all brain regions primarily function to make predictions…
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Send us a Text Message. The thalami are bilaterally symmetrical structures in the subcortical part of the brain that are cradled by the basal ganglia. They are major hubs of pretty much everything your brain does and all of the sensory information coming into the brain with the exception of smell. More primitive models of the brain visualized it as…
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Seroquel (Quetiapine) - Drugs, Sex, Money and Psychopharm
24:53
24:53
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Send us a Text Message. In this episode, I discuss a medication that patients who saw a psychiatrist or their primary care provider between about 1997 and 2015 were very likely to find themselves prescribed. More recently, it has been taken down a notch or two on prescribers lists of preferred meds. This medication is quetiapine, marketed as Seroqu…
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April 2024: Neural Responses to Intranasal Oxytocin in Youths With Severe Irritability
27:39
27:39
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Dr. Soonjo Hwang (University of Nebraska Medical Center) joins AJP Audio to discuss the response to intranasally-administered oxytocin in youths with severe irritability. 00:56 Hwang interview 02:09 Effects of oxytocin 05:45 Intranasal oxytocin 07:04 Potential adverse effects of oxytocin 08:08 Imaging 08:58 Preliminary investigations and clinical i…
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Send us a Text Message. This episode continues an intermittent series called “In a Word.” Past episodes have explored words like Akathisia, Dissociation, Perseveration, and even the difference between Impulsive and Compulsive. This episode explores Confabulation, including some of the brain circuits involved, and what might differentiate confabulat…
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How guilty are adolescents for their crimes?
29:31
29:31
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29:31
Send us a Text Message. In 2012 the Supreme Court heard two related cases involving adolescents convicted of murder and sentenced to life in prison without parole because of mandatory minimum sentencing guidelines in their states. One of the boys, Evan Miller along with an accomplice, had beat a man unconscious with a baseball bat after a fight tha…
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March 2024: Intergenerational Effects of the Fast Track Intervention on Next-Generation Child Outcomes: A Preregistered Randomized Clinical Trial
27:55
27:55
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27:55
Dr. Drew Rothenberg (Duke University, Durham, NC) joins AJP Audio to discuss the long term, intergenerational impacts of the Fast Track program, and whether the mental health intervention lead to lasting improvements in mental health, including in the participants own children. 00:49 Rothenberg interview 04:36 A null result? 07:13 At risk children …
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Serious Mental Illness in America with Dr. Zac Brooks
45:59
45:59
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45:59
Send us a Text Message. I am lucky today to be able to bring you an interview with Dr. Zac Brooks who is passionate about serious mental illness (SMI). “What is serious mental illness?” you might ask. That is one of the things we are going to discuss, and you may be surprised when Dr. Brooks explains how it was first formally defined. We also discu…
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HIV, PrEP, and Mental Health with Dr. Jon Lindefjeld
46:48
46:48
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46:48
Send us a Text Message. PsyDactic welcomes Dr. Jon Lindefjeld for a discussion of the history of HIV and AIDS. In particular, we discuss the development of effective antiretroviral therapies, including pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP), highlighting the CDC guidelines for use and monitoring, need to treat psychiatr…
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Perspectives on the Borderline: The Most Disordered Personality
40:07
40:07
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Send us a Text Message. Dr. O'Leary discusses some of the history of the borderline personality, how different perspectives have attempted to explain its origin, how to treat it and how not to treat it. He starts in 1947 with some colorful descriptions of patients living with borderline personality disorder that would never get published today, and…
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February 2024: Trends in Prevalence of Cannabis Use Disorder Among U.S. Veterans With and Without Psychiatric Disorders Between 2005 and 2019
21:56
21:56
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Dr. Ofir Livne (Columbia University, New York) joins AJP Audio to discuss recent trends in the prevalence of cannabis use disorder in US veterans with and without psychiatric disorder diagnosis. Dr. Ned Kalin joins afterwards to discuss how the rest of the February issue of AJP touches on cannabis use disorder and other substance use disorders. 00:…
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The Ghost of Personality Disorders Future
23:27
23:27
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23:27
Send us a Text Message. Our current diagnostic criteria for personality disorders have failed to demonstrate validity or reliability. The DSM 5 encouraged psychiatrists to start considering a broad range of personality features adapted from the Five Factor Model. These are combined with global functioning measures to build a personality inventory f…
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Send us a Text Message. Humans have a history of tattooing that stretches millennia into prehistory. The western ban on tattoos by the early church resulted in a systematic effort to paint tattooed individuals as pagan, primitive, vulgar, criminal, and mentally ill. Psychiatrists have historically contributed to this characterization but are in a p…
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Attractor Networks and the Bayesian Brain
58:06
58:06
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58:06
Send us a Text Message. The brain understands the world by building models that predict the future. One of the ways that it does this is by utilizing attractor networks. These small world networks are constantly trying to determine what is a true signal from the constant noise in the neural net. Dr. O'Leary explores how attractor networks have been…
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January 2024: Predicting Acute Changes in Suicidal Ideation and Planning: A Longitudinal Study of Symptom Mediators and the Role of the Menstrual Cycle in Female Psychiatric Outpatients With Suicidality ...
35:26
35:26
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Dr. Jaclyn Ross, Ms. Jordan Barone, and Dr. Tory Eisenlohr-Moul (University of Illinois at Chicago) join AJP Audio to discuss the impact of the menstrual cycle on suicide ideation and planning in psychiatric patients with suicidality. Afterwards, American Journal of Psychiatry Editor-in-Chief Dr. Ned Kalin brings us up to date on the rest of the Ja…
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