Hi, I'm Chris Masterjohn and I have a PhD in Nutritional Sciences. I am an entrepreneur in all things fitness, health, and nutrition. In this show I combine my scientific expertise with my out-of-the-box thinking to translate complex science into new, practical ideas that you can use to help yourself on your journey to vibrant health. This show will allow you to master the science of nutrition and apply it to your own life like a pro.
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For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own performance and embrace possibility with The Human Upgrade™. You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance ...
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The go-to source for the latest cutting-edge science on overcoming fatigue and increasing your energy. The Energy Blueprint podcast brings together the world's leading researchers, doctors, and nutrition and lifestyle experts on the subject of fatigue and energy to help you get your energy back.
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"If we learn to see problems in terms of a general disorder of energy metabolism, we can begin to solve them." —Raymond Peat PhD
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The Human Upgrade with Dave Asprey


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Making Billions: Lessons Learned From the King of the Thrill Pill Cult – Shaahin Cheyene : 1110
1:09:21
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Today’s guest is nothing short of a modern-day Willy Wonka for Generation X. He built a billion-dollar ecstasy business in the '90s and did not end up behind bars. That's a story you've got to hear. Our guest today, Shaahin Cheyene, not only dabbled in the wild world of herbal ecstasy but also managed to stay out of trouble despite being investigat…
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The Human Upgrade with Dave Asprey


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Hack Your Love Life: Hormones & Happiness – John Gray : 1109
1:45:04
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I’ve been eagerly looking forward to this conversation with a dear friend and a true luminary in the realm of relationships and personal development, John Gray. for quite some time. You probably recognize his name as the author of the famous book, Men Are From Mars, Women Are From Venus. But what's especially exciting is how John has evolved his in…
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Mastering Nutrition


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Is Hair Mineral Testing Useful? | Masterjohn Q&A Files #328
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Question: How useful is hair trace mineral analysis (HTMA) for nutritional testing? Short Answer: Hair trace mineral analysis is included as an optional add-on in the comprehensive nutritional screening from Testing Nutritional Status: The Ultimate Cheat Sheet, because it can capture data for some ultra-trace minerals for which there are no better-…
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The Energy Blueprint Podcast


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Change The World By Activating Your Heroic Potential with Brian Johnson
1:24:33
1:24:33
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In this episode, I’m speaking with Brian Johnson, founder and CEO of Heroic Public Benefit Corporation and the author of Areté: Activate Your Heroic Potential. I know Brian personally, and he is one of the most thoughtful, disciplined, and all-around interesting people I’ve ever met—I can’t wait to share this episode with you! In this podcast, Bria…
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Mastering Nutrition


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Secrets to Superior Cognitive Performance (Without Drugs)
51:10
51:10
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Nutrition is far more powerful than drugs to improve cognitive performance. We start by looking at cocaine, Adderall, and Ritalin, and show why these drugs cannot possibly hold a candle to nutrition. Optimal nutrition can definitely optimize the function of dopamine, norepinephrine, acetylcholine, histamine, creatine, and the methylation system, an…
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Mastering Nutrition


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Vitamin C, Whole Food Vs. Synthetic: Does It Matter?
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7:16
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Debunking the myth that vitamin C in plants is found in a special "tyrosinase complex." For the written article with references, see here: https://chrismasterjohnphd.substack.com/p/vitamin-c-whole-food-vs-synthetic For issues of vitamin C dosing and balancing with other nutrients, see these two links: https://chrismasterjohnphd.substack.com/p/the-p…
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The Human Upgrade with Dave Asprey


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Navigating the Quantum Field: Healing & Connection – Lynne McTaggart : 1108
1:24:33
1:24:33
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Today's episode delves deeper into the captivating world of quantum field therapy and the power of intention, featuring the renowned Lynne McTaggart. Lynne, known for her books "The Power of Eight," and “The Field” offers groundbreaking insights into the profound impact of group intention. The discussion unravels the significance of the number 8, e…
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Mastering Nutrition


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Fact-Checking Gary Brecka on Rogan: A Deep Dive into MTHFR and Methylation
6:03
6:03
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Watch or listen to the full critique here: https://www.youtube.com/watch?v=kMPvCiOkEtQ
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The Human Upgrade with Dave Asprey


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Falling Down & Getting Up: Exploring the Path to Resilience – Mark Nepo : 1107
1:09:56
1:09:56
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How about we have a conversation with one of the most spiritually influential living people on earth? Yes, you heard that right! Today's guest was bestowed with this honor by Watkins MindBodySpirit, and if that's not impressive enough, AgeNation awarded him a Life Achievement Award. Today, we have the incredible privilege of sitting down with a tru…
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The Energy Blueprint Podcast


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Mitochondria and Why We Need The Cell Danger Response | Robert Naviaux, MD
38:14
38:14
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In this episode, I’m speaking with Robert Naviaux, MD, Ph.D., the revolutionary mind behind the Cell Danger Response, a landmark contribution to the study of chronic fatigue and other long-term illnesses. In this podcast, Dr. Naviaux and I discuss: The true underlying driver of chronic illness, from myalgic encephalomyelitis to Lyme disease to depr…
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The Human Upgrade with Dave Asprey


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Human 2.0: The Cyborg Revolution Is Here – Kevin Warwick : 1106
1:07:56
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Today, we delve deep into the world of cybernetics and the potential cyberpunk future with a true pioneer and a living legend in the field, Kevin Warwick. As an Emeritus professor at Coventry and Reading Universities, Kevin is celebrated as the world's first cyborg, earning him the moniker: Captain Cyborg. In this episode, we explore the incredible…
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The Human Upgrade with Dave Asprey


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From Fog to Focus: The Hormone Hierarchy with Dr. LeBlanc : 1105
1:07:37
1:07:37
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Today, we talk about one of my favorite biohacking topics: hormones. Starting way back before I first had kids, I’ve studied hormones as they relate to fertility – leading to the first of just a few books over the years, The Better Baby Book. And it's been an area of passion ever since because hormones also control your mood and your energy levels …
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Mastering Nutrition


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Cancer, IV Drips, and the Glutathione Vitamin C Connection
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Is high-dose vitamin C good for you? High-dose intravenous vitamin C can selectively kill cancer cells in live patients and can save sepsis patients from dying, but it acts as a pro-oxidant in cancer and an antioxidant in sepsis. So what does it do in the rest of us? Oral doses of 2000 milligrams raise oxalate levels in most people, and as little a…
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Mastering Nutrition


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How to Find the Root Cause of Autoimmunity? | Masterjohn Q&A Files #327
20:38
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Question: How to Find the Root Cause of Autoimmunity? Short Answer: Autoimmune conditions are likely driven by deficiencies of vitamins A and D, which contribute to post-infectious autoimmunity by compromising the rhythmic rise and fall of myeloid-derived suppressor cells (MDSCs), and to autoimmunity regardless of infections through impaired suppre…
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The Energy Blueprint Podcast


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Foods & Supplements You NEED TO EAT For Longevity and Energy | Dr. Michael Murray
56:03
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Dr. Michael Murray talks about his favorite longevity and energy promoting foods and supplementsBy The Energy Blueprint Podcast
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The Human Upgrade with Dave Asprey


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Skin Deep: Carolina Oliveira Unveils Youth-Boosting Breakthroughs : 1104
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Today, let's delve into a topic often overlooked but crucial for our overall health: our skin. Over the past decade, I've started seeing our skin as more than just a protective layer; it's a major organ, just like our liver or heart. Its health goes beyond appearances – it profoundly influences our biology and well-being. Today, I welcome Carolina …
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The Human Upgrade with Dave Asprey


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How to Deal with Toxic People (Including Yourself) with Robert Greene : 1103
1:22:50
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In this episode of The Human Upgrade my guest fits right into the podcast transition to The Human Upgrade because he gets into the grittiness of what humans can do to level themselves up. No. 1 New York Times bestselling author Robert Greene shares science-backed knowledge about human nature. You know you want to be more powerful, more in control a…
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Mastering Nutrition


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The Powerful Duo: How Glutathione and Vitamin C IV Drips Impact Cancer
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High-dose intravenous (IV) vitamin C has the potential to kill cancer cells and prolong the survival of terminal cancer patients. This podcast is a preview, the full video is available only to Masterpass members. See the written article with links to references here: https://chrismasterjohnphd.substack.com/p/the-powerful-duo-how-glutathione Subscri…
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The Human Upgrade with Dave Asprey


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Quantum Biology: The Future of Healing and Biohacking – Dr. Catherine Clinton : 1102
1:03:51
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Let’s explore the mind-bending subject of quantum biology with Dr. Catherine Clinton, a licensed naturopathic physician with a focus on gut health, autoimmunity and psychoneuroimmunology. A respected author, speaker, health advocate, Dr. Clinton has been on the front lines of health and wellness for over 15 years, helping people overcome the very h…
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The ability to become startled is an adaptive behavior that protects us from being injured by a sudden threat, and prepares us for the fight-or-flight response when necessary. Nevertheless, getting startled too easily can be a sign that something is wrong. Here's what to do about it. For the written version with links to references and links to tes…
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The Energy Blueprint Podcast


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Heart-Brain Coherence | A Powerful Key To Healing with Dr. Christine Schaffner
1:10:47
1:10:47
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In this episode, I’m speaking with Dr. Christine Schaffner. Dr. Schaffner is a board-certified naturopathic physician who focuses on “mystery illnesses”—she’s helped thousands of patients recover from chronic, complex conditions. I’m also excited to share an invitation to her upcoming summit—The Art & Science of Cultivating Coherence Summit—FREE fr…
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Hormones matter, but they are never in charge. Their abnormalities are never the root cause of anything. All hormones do is communicate the biochemistry of one tissue to the biochemistry of another tissue. In this episode: Three Reasons For Hormones to Be Messed Up Exceptions to the Rule Leptin, Insulin, and Thyroid Hormone As an Example How to App…
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Mastering Nutrition


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Biotin’s Health Benefits: Way Beyond Hair and Nails
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7:01
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Most people who take biotin take it for their hair and nails. Yet biotin does much more than this. Learn what to use it for, how much to take, and how to avoid adverse effects in less than ten minutes. Read the written and fully referenced version here: https://chrismasterjohnphd.substack.com/p/biotins-health-benefits-way-beyond Get my short and sw…
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The Human Upgrade with Dave Asprey


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Biohack Your Plate: Genetics, Gut & Perfect Nutrition – Matt & Wade of BiOptimizers : 1101
1:11:46
1:11:46
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Remember the days when we believed in one-size-fits-all diets? Well, thankfully those days are behind us. Today's episode is all about the crucial shift towards personalized nutrition. Our guests, Matt Gallant and Wade Lightheart from BiOptimizers, are no strangers to the show. They're also the authors of The Ultimate Nutrition Bible, a monumental …
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The Human Upgrade with Dave Asprey


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Introducing a REAL Superfood: Using Colostrum for Strong Barriers – Sarah Rahal, MD : 1100
1:09:04
1:09:04
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About ten years ago, I began working colostrum into my product development efforts – seeing its game changing nutritional value for exactly what it was, well before the mainstream sank its teeth into it. Today’s guest has the experience and intellect to take us deep into the science behind it. Dr. Sarah Rahal, MD – the brainchild of ARMRA – is a do…
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Mastering Nutrition


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Exposing Harmful Supplements: Biotin's Dark Side
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This is how to use a simple home measurement to expose the harmful effects of a supplement before they even happen. Read the article here: https://chrismasterjohnphd.substack.com/p/the-dark-side-of-biotin Subscribe to my newsletter to get my series on improving respiratory chain function as soon as new articles come out: https://chrismasterjohnphd.…
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Mastering Nutrition


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Why Would Vitamin C cause muscle pain, joint pain, and brain fog? | Masterjohn Q&A Files #326
27:44
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Question: Why Would Vitamin C cause muscle pain, joint pain, and brain fog? Short Answer: Acutely, vitamin C would likely cause these effects by generating oxalate, which could cause crystals that lead to muscle and joint pain, and could cut energy metabolism in half, leading to brain fog. This vulnerability could result from deficiencies of any of…
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The Energy Blueprint Podcast


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Dr. Gabrielle Lyon - LONGEVITY Do This To BUILD MUSCLE & LIVE Longer!
1:06:44
1:06:44
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In this episode, I’m speaking with Dr. Gabrielle Lyon, founder of the Institute for Muscle-Centric Medicine®, about her new book, Forever Strong. I believe Dr. Lyon’s message is so crucial that I bought her book for myself and my parents—this episode is a must-listen! In this podcast, Dr. Lyon and I discuss: The completely overlooked driver of card…
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The Human Upgrade with Dave Asprey


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Kids vs. Big Food: Food Babe’s Playbook for Healthy Choices - Vani Hari : 1099
1:02:22
1:02:22
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Friends, it is my great pleasure to introduce Vani Hari, aka Food Babe, someone I've had the privilege of knowing for nearly a decade. She is a relentless advocate for clean, safe, and wholesome food. She has dedicated herself to a tireless campaign aimed at eliminating harmful ingredients from our food supply, particularly in the United States, wh…
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The Human Upgrade with Dave Asprey


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How I Took 9 Years off My Age: Live From Toronto with Gene Therapy Pioneer Dr. Adeel Khan : 1098
1:50:45
1:50:45
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In this episode, we're broadcasting live from Toronto with Dr. Adeel Khan, a leading figure in the field of gene and cell therapies. Dr. Adeel Khan, who holds an M.D. and is a Canadian Board Certified Physician, specializes in regenerative and cellular medicine. He is also a recognized authority as a key opinion leader for The American College of R…
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Mastering Nutrition


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Why You Need THIS Supplement On a High-Protein Diet: Game-Changing Effects Explained by a PhD
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If you are eating a high-protein diet, you probably aren’t getting enough biotin. This is especially true if you are a protein-fueled athlete and find your skin too oily, too itchy, or too red; if your blood sugar is getting out of control; or if you simply feel down in the dumps. And it’s especially true if you find your hands or feet tingling or …
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Mastering Nutrition


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Why High-Dose Biotin Could be the Answer for Your Blood Sugar, Brains, and Beauty
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The use of high-dose biotin supplements has increased almost 30-fold over the last twenty years for such problems as diabetes, smell and taste disorders, disorders of the hair, skin, and nails, and multiple sclerosis. Studies show it can improve diabetes, and case reports show it can miraculously recover lost smell and taste even when smell and tas…
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