Can PTU Cause Permanent Liver Damage?

Save My Thyroid

Compared to other anti-thyroid medications such as methimazole, propylthiouracil (PTU) is not commonly prescribed by endocrinologists. It’s generally only prescribed in specific cases where the methimazole is contraindicated or not well tolerated.
It's not uncommon for PTU to cause elevated liver enzymes, and in rare cases, that can lead to liver damage. Thankfully, this is not something I’ve experienced in my practice, as it’s a rare side effect. Today, I’m sharing what the research shows about PTU's potential negative impact on the liver.
In this episode, you’ll learn about:
- PTU’s mechanism of action
- The most common scenarios where PTU is given
- Case studies on the potential connection between taking PTU and liver damage
- Recommendations for PTU use and monitoring of liver markers
- How PTU can interfere with vitamin K activity
As always, I hope you find this episode valuable, and I look forward to catching you in the next episode!
To learn more, visit the show notes at https://savemythyroid.com/podcast/can-ptu-cause-permanent-liver-damage/.

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