Best Biophysics Podcasts (2024)

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Episode: 64 - Peyton Greenside on AI’s Role in Antibody Engineering, Optimization, and More 32:31

2h ago32:31

32:31

In this episode of The Chain, host Nimish Gera, Ph.D., vice president of biologics at Mythic Therapeutics, speaks with Peyton Greenside, CSO and co-founder of BigHat Biosciences, about the role of AI and machine learning in antibody engineering and targeting complex modalities, including bispecifics and ADCs. Greenside also discusses the work her o…

1
Episode: 63 - Discussing Protein Signaling and Structural Biology With Andrew Kruse 38:18

28d ago38:18

38:18

In this episode of The Chain, host Brandon DeKosky, associate professor at MIT, speaks with Andrew Kruse, PhD, professor of biological chemistry and molecular pharmacology at Harvard University, about protein signaling and structural biology. Kruse explains what exactly bias signaling is and discusses the problems he and his team are working to res…

1
Episode: 62 - AI/ML in Antibody Discovery and Engineering: Reality, Hope, Future, and Hype 1:03:57

2M ago1:03:57

1:03:57

his special episode of The Chain features a panel of industry experts who discussed AI and ML in antibody discovery and engineering at this year’s PEGS Boston event. Peter Tessier, professor at the University of Michigan; Andrew Bradbury, CSO at Specifica; Andrew Waight, Senior Director of Machine Learning, Discovery Biologics & Protein Sciences at…

1
Episode: 61 - Tomoyuki Igawa Discusses Leadership and His Experiences in Discovery and Development 55:04

3M ago55:04

55:04

In this episode of The Chain, host Tariq Ghayur, PhD, consultant and entrepreneur in residence, FairJourney Biologics, speaks with Tomoyuki Igawa, PhD, chief executive officer, Chugai Pharmabody Research in Singapore, about his 20+ years of experience in drug discovery and development. Igawa possesses a unique perspective that has allowed him and h…

1
Episode: 60 - Lesley Millar-Nicholson on Technology Licensing, Navigating Patents, and Building Teams 48:14

5M ago48:14

48:14

This month The Chain shares a recent episode of the Lab Rats to Unicorns podcast. Lab Rats to Unicorns, hosted by John Flavin, aims to demystify the process of creating a great company in the life sciences, biotech, medtech, clean energy, and beyond. In this episode, Flavin speaks with Lesley Millar-Nicholson, executive director of MIT’s Technology…

1
Episode: 59 - Gabriel Rocklin on Protein Biophysics and Protein Design 33:10

5M ago33:10

33:10

In this month’s episode of The Chain, host Ben Hackel, professor of Chemical Engineering & Materials Science at the University of Minnesota, speaks with Gabriel Rocklin, assistant professor of Pharmacology at Northwestern University, about two recently published papers from Rocklin’s lab: one on advancing the ability to design challenging typologie…

1
Episode: 58 - Janine Schuurman Reflects on the Key Lessons and Accomplishments of Her 20-Year Career 55:05

7M ago55:05

55:05

How does one maintain innovation in the antibody industry? In this episode of The Chain, host Tariq Ghayur, PhD, consultant and entrepreneur in residence, FairJourney Biologics, talks with Janine Schuurman, PhD, president of The Antibody Society, independent biotech consultant and founder of Lust for Life Sciences, about her inspiration to get into…

1
Episode: 57 - The Future of Bispecific Antibody Drug Conjugates With Rakesh Dixit, Ph. D. 33:06

8M ago33:06

33:06

Bispecific antibody drug conjugates (ADCs) have been undergoing a renaissance in recent years. As big pharma continues to express more interest, what can the field expect for the future of ADCs? In this episode of The Chain, Nimish Gera, Ph. D., Vice President of Biologics of Mythic Therapeutics, speaks with Rakesh Dixit, Ph. D., President & CEO of…

1
Episode: 56 - Thomas Sakmar on the Golden Age for the Application of Biologics to GPCR Pharmacology 44:38

8M ago44:38

44:38

What can we expect from GPCRs in antibodies and biologics? In this episode of The Chain, host Rajesh Sundaresan, PhD, Scientific Leader and GSK Fellow of Protein Cell and Structural Sciences at GlaxoSmithKline, speaks with Thomas P. Sakmar, MD, Professor of Chemical Biology at Rockefeller University, about the history of GPCRs and various subunits,…

1
Episode: 55 - Tala Fakhouri Discusses AI/ML for Biologics Drug Discovery & Development 33:27

9M ago33:27

33:27

In this episode of The Chain, Richard Bonneau, PhD, and Marcel Hop, PhD, of Genentech interview Tala Fakhouri, PhD, of the FDA on her thoughts on the discussion paper, “Using Artificial Intelligence & Machine Learning in the Development of Drug & Biologic Products” and the evolving role of AI/ML to create models and inform decisions in biopharmaceu…

1
Episode: 54 - Enkelejda Miho on the Current State of AI: Drug Development, Research, and the Future 29:20

10M ago29:20

29:20

With the whirlwind development of AI, it can be difficult to keep track of its uses in both research and the market. In this episode of The Chain podcast, host Ben Hackel, Professor of Chemical Engineering & Materials Science at the University of Minnesota, speaks with Enkelejda “Ledi” Miho, Professor of Digital Life Sciences at the University of A…

1
Episode: 53 - Jonathan Sockolosky on Breaking Into Biotech and Making Real Progress in Ovarian Cancer Treatments 26:48

12M ago26:48

26:48

What is the first step of getting into biotech? How do you make real progress in research? In honor of Ovarian Cancer Awareness Month, host Nimish Gera discusses these topics and more with Jonathan Sockolosky, PhD, Director of CSO Partner Team at Curie.Bio, in this special episode of The Chain. Jonathan details how he got started in biotech, what i…

1
Episode 52: Entrepreneurship in Immunotherapy: Capstan’s Adrian Bot on Teambuilding 23:31

1y ago23:31

23:31

In this episode of The Chain, Brandon Dekosky, Associate Professor at MIT, speaks with Adrian Bot, Founding Chief Scientific Officer and Executive Vice President of R&D at Capstan Therapeutics, about his experiences in leadership roles, his scientific journey, and how he started work on immunotherapy for cancer. Bot also shares what it's like to be…

1
Episode: 51 - Setting the Right Strategy to Drive Engineering Parameters for Solid Tumor-Targeting T Cell-Engagers 53:45

1y ago53:45

53:45

In this special episode of The Chain, G. Jonah Rainey, Senior Director of Protein Engineering at Eli Lilly and Company, hosts a panel at PEGS 2023 to discuss strategies to engineer parameters for solid tumor-targeting T-cell-engagers. Guests Stephen J. Demarest from Tentarix Biotherapeutics, Michelle Morrow from F-Star Therapeutics, Inc., and Dario…

1
Episode: 50 - Pivoting Research with Antibody Drug Conjugates 31:20

1y ago31:20

31:20

In this month’s episode of The Chain, Greg M. Thurber, associate professor of chemical engineering and biomedical engineering at the University of Michigan, sits with moderator Nimish Gera, vice president of biologics at Mythic Therapeutics, to talk about the development of antibody drug conjugates (ADCs). Thurber details the history of ADCs and th…

1
Goodbye Better 1:11:53

1+ y ago1:11:53

1:11:53

The end of the hyperspace journey has finally arrived. We go through some of our all time favorite segments and thank those who joined us along the way...our friends.

1
S7E06 - Talking X-Wing with Duncan Howard 1:16:19

1+ y ago1:16:19

1:16:19

This week we bring on X-Wing all star Duncan Howard to discuss his recent successes. Be sure to send your extra language Store Championship prizes to Chris Allen so he can help distribut them worldwide! Chris Allen 1319 Military Cutoff Suite CC #42069 Wilmington, NC 28405

1
S7E05 - Mentally Prepping for Store Champ Season 1:06:51

1+ y ago1:06:51

1:06:51

This week we talk about how you can get ready for upcoming store champs, and in addition tips for if this is your first competitive season!

1
Episode: 49 - Building a Next Generation Bioproduction Platform 23:30

1+ y ago23:30

23:30

Kyron.Bio is revolutionizing drug production with its Next Generation Bioproduction Platform that will make the production of therapeutics easier, cheaper and faster. Voldborg and McLaughlin talk about their shared vision for using synthetic biology to improve the production of therapeutic proteins. Kyron.Bio: https://kyron.bio/…

1
S7E04 - Community Building with Geoff Moore 1:16:03

1+ y ago1:16:03

1:16:03

We bring on X-Wing Community leader Geoff Moore to talk about how you can help rebuild your local communities.

1
S7E03 - Mail Call! 1:13:34

1+ y ago1:13:34

1:13:34

This week we are joined by Victor Cepeda to talk about his victory in a recent tournament in Chile, then we answer YOUR burning listner questions!

1
S7E02 - Hit Hit Eye with World Champion Niklas God 1:09:15

1+ y ago1:09:15

1:09:15

This week we bring on 2023 World Champion Niklas God to talk about his tremendous run. After a bit of precarious start, Niklas managed to cement the power of the First Order as the top faction in the universe! Niklas' List https://yasb.app/?f=First%20Order&d=v9ZhZ20Z262X119W181W186WY627X119W186WWY625X119WWW11WY242X119WW186WW182WY266XWW311WWY383X124…

1
Episode: 48 - A Conversation with Peter Tessier: Classifying Antibodies to Assess Biologics Developability Features Early in the Discovery Process 48:01

1+ y ago48:01

48:01

In this month’s episode of the Chain, guest Peter Tessier, Albert M. Mattocks pharmaceutical sciences and chemical engineering professor at the University of Michigan, speaks with moderator Tariq Ghayur, scientific advisor and entrepreneur in residence at FairJourney Biologics, about expediting the developability of antibodies. He discusses the cha…

1
S7E01 - Hit Hit Blank with Worlds Finalist Andrew Cox 1:06:29

1+ y ago1:06:29

1:06:29

Worlds has concluded in spectacular fasion! This week we bring on 2023 Worlds Finalist Andrew Cox to talk about his rise from the ashes to make it to the final table. Andrew's List https://yasb.app/?f=Galactic%20Empire&d=v9ZhZ20Z564X125W204W105Y566X127W105Y565X116W381W105Y218X119WW11WWY184XW60WW&sn=Worlds%202023%20-%20Andrew%20Cox&obs= All Worlds L…

1
Episode: 47 - Bonus Episode with PEGS Young Scientist Keynote Dr. Andrew Anzalone on Engineering Prime Editor Proteins for Therapeutic Applications 40:43

1+ y ago40:43

40:43

Dr. Andrew Anzalone, head of the Prime Editing Platform and scientific co-founder at Prime Medicine, is the winner of the PEGS Boston 2023 Young Scientist Keynote. He was invited to sit down with Brandon DeKosky, assistant professor of chemical engineering at MIT, to discuss prime editing and its precision in treating inherited genetic mutations. A…

1
S6E11 - Worlds Primer 6 Imperial & CIS with Biophysical 1:11:30

1+ y ago1:11:30

1:11:30

This week we bring on Biophysical, the master of the Empire, to talk about how the bad guys can win worlds. Then we fumble in the dark trying to discuss Separatists. Check out Ryan's Game on Kickstarter! https://www.kickstarter.com/projects/almanacgames/encounters-shattered-wastes

1
Episode: 46 - Leveraging Albumin and IgG FcRn-Mediated Regulation in Therapeutic Development 36:20

1+ y ago36:20

36:20

Jan Terje Andersen, professor of biomedical innovation in the Department of Pharmacology at the University of Oslo and research group leader in the Department of Immunology at the Oslo University Hospital, has spent nearly two decades studying neonatal Fc receptors (FcRns) and their interactions with prominent blood proteins albumin and IgG. He sit…

1
S6E10 - Worlds Primer 5 Scum & Resistance with Raithos 1:11:34

1+ y ago1:11:34

1:11:34

This week we bring on Yet Another Squad Builder Man himself, Stephen Kim/Raithos, to talk about how Scum or Resistance can win worlds! Check out Ryan's Game on Kickstarter! https://www.kickstarter.com/projects/almanacgames/encounters-shattered-wastes

1
S6E09 - Worlds Primer 4 Sad Rebels with Wynand Coert 1:02:16

1+ y ago1:02:16

1:02:16

This week we bring on (mostly) loyal Rebel player Wynand Coert to discuss what the much malaigned faction can do to have a shot a worlds. (Spoilers: not a ton). Also we lament the return of the tyranny that is 3 agility. Check out Ryan's Game on Kickstarter! https://www.kickstarter.com/projects/almanacgames/encounters-shattered-wastes…

1
Finding a Chiropractor in Santa Ana 0:36

1+ y ago0:36

0:36

We hope this article has been helpful for you. While one chiropractor may be the best for one particular person you may find that another is the best for you. Using your own judgment and common sense can go a long way in the determination process. If you have any further questions please feel free to contact our Santa Ana team today at Corrective C…

1
Is It Just Back Pain in Santa Ana? 0:44

1+ y ago0:44

0:44

If you have experienced back pain in your life you are part of an overwhelming majority in Santa Ana. Most of us will experience back pain at one time or another following heavy or awkward lifting, or after a hard workout. If the pain is coming from a strained muscle, it will most likely resolve itself in a few days of rest. If the pain is not musc…

1
How Chiropractic BioPhysics® Can Help You Get Relief from Injury and Pain 1:32

1+ y ago1:32

1:32

Whether you have scoliosis, chronic back pain, or just need some general realignment work done, Chiropractic BioPhysics® offers a safe and effective way to get lasting relief from injury and pain without needing invasive or expensive treatments. All in all, Chiropractic BioPhysics® truly sets us apart at Corrective Care Chiropractic. By offering lo…

1
S6E08 - Worlds Primer 3 Republic with Liam Lee and Tyler Tippett 1:16:57

1+ y ago1:16:57

1:16:57

We have a couple Republic LVO ALL STARS on the cast today to break down the faction. Liam Lee and Tyler Tippett have different ways to approach the Jedi/Clone flyers, but both are effective! Check out Encounters: Shattered Wastes https://www.kickstarter.com/projects/almanacgames/encounters-shattered-wastes…

1
S6E07 - Worlds Primer 2 The First Order with Mitch Hurst 1:05:56

1+ y ago1:05:56

1:05:56

This week we continue our road to Worlds by talking about what the First Order has to offer! LVO Runner Up* Mitch Hurst joins us to talk about why his 6 ship FO squad could be the one to look out for come Adepticon. Check Out Encounters: Shattered Wastes, designed my host Ryan Farmer: https://www.kickstarter.com/projects/almanacgames/encounters-sha…

1
S6E06 - Worlds Primer 1 with TO Chris Allen 1:11:55

1+ y ago1:11:55

1:11:55

Worlds 2023 Tournament Organizer Chris Allen joins the podcast to talk about all the important Judging items YOU need to know before Worlds arrives next month! https://www.gofundme.com/f/help-xwing-2023-world-championship-judges-travel

1
Episode: 45 - Advances in Targeted Protein Degradation 30:16

1+ y ago30:16

30:16

In this month’s episode of the Chain, Jim Wells, professor of pharmaceutical chemistry and cellular and molecular pharmacology at the University of California, San Francisco, sits down with moderator Ben Hackel, associate professor of chemical engineering and materials science at the University of Minnesota, to discuss Wells’ work in advancing targ…

1
S6E05 - Dooku, Durge, And Bombs Win LVO with James Stumbo 1:17:19

1+ y ago1:17:19

1:17:19

This week we bring on James Stumbo to talk about his excellent run at the Las Vegas Open! We talk about why people are wrong for attacking Dooku, and how three Bombardment Drones and dream can win big events. Check out the Encounters: Shattered Wastes Kickstarter! https://www.kickstarter.com/projects/almanacgames/encounters-shattered-wastes…

1
X-Wing 2023 Beginner Guide 1:05:48

1+ y ago1:05:48

1:05:48

OFFICIALAtomic Mass Games X-Wing DocumentsRules Forum UNOFFICIALUnofficial Updated Core Set Rulebook SQUAD BUILDERS Yet Another Squad Builder 2 Launch Bay Next Infinite Arenas PODCASTS/TWITCHSTREAMS Gold Squadron Podcast Hexiled Gaming Out Of The Mines Salt Mines Thule Squadron Radio DISCORDS/COMMUNITIESFly Better Discord Fly Better Facebook Caroli…

1
S6E03 - The Annexation of POErto Rico 1:15:04

1+ y ago1:15:04

1:15:04

This week Dee returns from being sick and the Fly Better team does a deep dive into Resistance Poe Dameron, a ship that both hosts feel should be explored more.

1
S6E02 - The Taxation of Points Trade Routes with Travis and Jeremy 1:50:35

1+ y ago1:50:35

1:50:35

This week Ryan brings on Travis "A Johnson" Johnson and Jeremy Chamblee to talk about LVO Preparation. The three go over the pieces they feel are strong in each faction.

1
Episode 44: Structure Forward: Using Structural Biology Pipelines to Achieve Favorable Antibody Responses 31:46

1+ y ago31:46

31:46

Over the last two decades, cryogenic electron microscopy (cryo-EM) has transformed from what Dr. Andrew Ward calls the “outcast of structural biology” to one of the most promising technologies in the field. Ward, professor of integrative structural and computational biology at Scripps Research Institute, speaks with moderator Brandon DeKosky, assis…

1
S6E1 - Welcome to 2023 X-Wing 1:32:20

1+ y ago1:32:20

1:32:20

This week we muse about the future of X-Wing and answer some burning Listener Questions! [00:00:00] Intros/Updates/Nonsense [00:20:00] Future of X-Wing musings [00:40:00] RBCD: SoC Anakin and Obi-Wan [00:55:00] Listener Q&A

1
S5E41 - Andor Discussion with Spoilers Intended 1:43:57

1+ y ago1:43:57

1:43:57

This week the Spoilers Indended crew joins the cast to take a break from X-Wing and chat about Andor! Learn more about Spoilers Indended here: https://www.spoilersintendedpodcast.com/

1
Episode: 43 - Evolution of Antibody Technologies 28:26

1+ y ago28:26

28:26

Dame Jane Osbourn, chief scientific officer at Alchemab Therapeutics, speaks with Ahuva Nissim, antibody and therapeutic engineering professor at Queen Mary University of London William Harvey Research Institute, about the career path that took her from studying molecular biology and building human phage libraries to developing therapeutics with co…

1
S5E40 - PAX Roundup with Phil Karash 1:44:43

1+ y ago1:44:43

1:44:43

This week Phil Karash comes on to talk about his PAX winning squad as well as whether Balto is more popular than Jason Derulo? [00:00:00] Intros/Updates/Balto [00:10:00] RPCD: Lin Gaava [00:25:00] ABZ with Phil [00:25:00] Vader Defender wins! [01:10:00] PAX Top 8 https://discord.gg/carolinakrayts

1
S5E39 - Tournament Structures with Chris Allen 2:25:18

2y ago2:25:18

2:25:18

This week Chris Allen joins the podcast to talk about his excellent essay on tournament structures in X-Wing. Then Hotshots and Aces II points are brought to court to be judged by all! [00:00:00] Intros/Updates [00:10:00] Tournament Structures [01:10:00] Hotshots Aces II Points Discussion https://discord.gg/carolinakrayts https://chrisalleng.substa…

1
S5E38 - Resistanning for Nimi 1:36:50

2y ago1:36:50

1:36:50

This week Ryan tried to convince Dee that Nimi is a resistance piece players are overlooking. Also, the topic of preparation and objective focused squadbuilding mindsets are brought to the table. Finally, Poe or Lando? This week we talk about some Hot Shots and Aces II reveals, followed by a couple of big WOQ Roundups! [00:00:00] Intros/Updates [00…

1
S5E37 - A Formal Apology To Ahkter 2:09:04

2y ago2:09:04

2:09:04

This week we talk about some Hot Shots and Aces II reveals, followed by a couple of big WOQ Roundups! [00:00:00] Intros/Updates [00:05:00] Hotshots Aces II Pilot Discussion [00:58:00] Nordic WOQ Top 8 [01:25:00] Australian WOQ Top 4 [01:35:00] Political(?) After Dark Isophane Initiative Nodic WOQ Replay Farmer's Reddit Post https://www.kickstarter.…

1
S5E36 - A Blessing and a Dark Curse with Herman Ruddell 2:04:03

2y ago2:04:03

2:04:03

This week we bring on Golden State Games WOC Top 4 player Herman Ruddell the Third to talk about why several of the new BoY Pilots should be taken seriously. Following that we breakdown the top 12 lists from the qualifier this past weekend with a few surprises. [00:00:00] Intros/Updates [00:07:00] Battle of Yavin Pack Review [00:18:00] RPCD: Dark C…

1
Episode: 42 - Machine Learning Informatics for Antibody Discovery 36:04

2y ago36:04

36:04

Charlotte Deane, professor of structural bioinformatics at the University of Oxford and upcoming speaker at the 14th Annual PEGS Europe Conference in Barcelona, joins moderator Brandon DeKosky, assistant professor of chemical engineering at the Massachusetts Institute of Technology, to discuss the use of machine learning in antibody structure predi…

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