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The Chain: Protein Engineering Podcast

Cambridge Healthtech Institute

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The Chain explores the lives, careers, research, and discoveries of protein engineers and scientists, the impact their work is having on the field, and where the industry is headed. Tune in to stay up-to-date on the newest advancements and to hear the stories that are impacting the world of biologics.
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Advanced Health South Loop

Advanced Health South Loop

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South Loop Health’s state-of-the art facility is equipped with the latest technology used to apply the most advanced techniques to provide top level alternative health care services that do not rely on medication or surgery. We can provide you and your family with the health, wellness and care to help with numerous conditions. The best chiropractic services in the city can be had with Dr. Luke Stringer at Advanced Health South Loop!
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MRC talks is a podcast from the Medical Research Council, bringing you stories from inspiring scientists working to improve lives through medical research. Tune in to our seven-part 2019 career inspirations series to find out how our scientists got to where they are and what makes them tick. Part of UK Research and Innovation, we've been funding research dedicated to improving human health since 1913. More at https://mrc.ukri.org.
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Corrective Care Chiropractic Clinic (https://correctivecarechiropractic.com/) is a Chiropractic BioPhysics trained chiropractor specializing in a much more focused, complete, and detailed approach to pain relief and spinal rehabilitation in Santa Ana, California. We are focused on addressing the root cause of pain, ensuring that the source is treated, resulting in a more permanent solution to a healthier and happier life. See more about us: Phone: +1 657-218-9026 Address: 540 N Golden Cir Dr ...
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Welcome to the Fly Better Podcast, the best source to become an Ace Pilot! Every week Dee, Ryan, and Dallas bring you the latest news, tips, and deep dives into the world of X-Wing Miniatures. Awarded the Best US X-Wing podcast at the 2018 Goldies. Now with 2 out of 3 hosts having won a Regional. Skreeeeeee!
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Whether you find spiders fearful or fascinating, they are to be admired for their web-spinning and prey-catching techniques, and the remarkable methods they use to move from one place to another. In this album, researchers in Denmark and the United States use an 8-legged robot and a virtual spider, high-speed photography, a hot air balloon and a rowing boat to explore the biophysics of spiders. In the audio track, Dr David Robinson of The Open University explains how advances in technology a ...
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Whether you find spiders fearful or fascinating, they are to be admired for their web-spinning and prey-catching techniques, and the remarkable methods they use to move from one place to another. In this album, researchers in Denmark and the United States use an 8-legged robot and a virtual spider, high-speed photography, a hot air balloon and a rowing boat to explore the biophysics of spiders. In the audio track, Dr David Robinson of The Open University explains how advances in technology a ...
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In this month’s episode of The Chain, host Ben Hackel, professor of Chemical Engineering & Materials Science at the University of Minnesota, speaks with Gabriel Rocklin, assistant professor of Pharmacology at Northwestern University, about two recently published papers from Rocklin’s lab: one on advancing the ability to design challenging typologie…
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There is growing scientific literature on the benefits of red light therapy/photobiomodulation for a wide range of medical and and health optimisation strategies. This is a comprehensive introduction to the topic and great starting point for anyone looking to add this practice to their health and wellness toolkit. Andrew LaTour is an expert enginee…
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We discuss the most important factors influencing health - how light and changes man-made changes in the electromagnetic spectrum influence mitochondria, circadian rhythms and are contributing to modern chronic disease. Cameron Borg is a qualified nutritionist, practicing pulmonary scientist, podcaster and health coach from Sydney, Australia. He ho…
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In this groundbreaking interview with world expert Dermatologist Richard Weller, we discuss sunlight, skin cancer and the profound findings of large population-based studies that INCREASED ultraviolet (UV) light and greater sunlight is associated with LESS all cause mortality, less cardiovascular mortality and less cancer mortality, including skin …
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I speak with world expert on deuterium depletion and cancer, Dr Gabor Somylai, from Hungary. He has dedicated his professional life to understanding and treating cancer using by reducing the concentration of the heavy hydrogen isotope, deuterium, in the body. This involves drinking deuterium-depleted water adopting a very high animal fat ketogenic …
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Drawing on historical, anthropological and current scientific evidence, Dr Anthony Chaffee & I discuss the logical flaws of blaming red meat and animal-derived fats for modern chronic diseases. We also cover the true underlying causes of heart attacks (atherosclerotic cardiovascular disease (ASCVD)), with specific reference to thrombogenic hypothes…
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On Sunday April 21st, the holistic health summit is coming to Melbourne with an epic event held at the iconic Fitzroy venue, 75 Reid St. REGENERATE connects you with the most innovative speakers on health optimisation though Circadian & Quantum Health, Carnivore & ancestral diets and Regenerative Farming in Australia. Featuring a powerhouse line-up…
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How does one maintain innovation in the antibody industry? In this episode of The Chain, host Tariq Ghayur, PhD, consultant and entrepreneur in residence, FairJourney Biologics, talks with Janine Schuurman, PhD, president of The Antibody Society, independent biotech consultant and founder of Lust for Life Sciences, about her inspiration to get into…
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Fifth generation (5G) telecommunications technology is now everywhere, but what are the effects on human health? This is a question I explore with electrical engineer and EMF expert Tristan Scott. We cover the difference between 5G and previous bands, the science behind radiofrequency (RF) impacts on biology, how non-native electromagnetic fields (…
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Stephen and I explore the causes and prevention of aetherosclerotic cardiovascular disease (ASCVD) from a biophysics perspective, leaving behind the biochemical, lipid-based model of heart disease. We discuss the role of clotting in acute myocardial infarction, endothelial health, fourth phase of water, sunlight and the impact of deuterium on mitoc…
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This is a deep dive into the nuances of artificial light vs sunlight, the difference between narrow and broadband infrared light sources, how infrared light affects mitochondrial function, how we evolved to harvest IR light from our environment and much more. Scott Zimmerman is an expert optics engineer and research scientist who is raising awarene…
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Bispecific antibody drug conjugates (ADCs) have been undergoing a renaissance in recent years. As big pharma continues to express more interest, what can the field expect for the future of ADCs? In this episode of The Chain, Nimish Gera, Ph. D., Vice President of Biologics of Mythic Therapeutics, speaks with Rakesh Dixit, Ph. D., President & CEO of…
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Matthew Lysiak is an investigative journalist and author of the book 'Fiat Food'. We discuss the corrupt history of the dietary guidelines in the USA, starting with the influence of Seventh Day Adventist Church in the early 1900s, as well as the Food Industry lobbying and capture of academic institutions to further grain-based & processed food reco…
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Dr Deepa Mahananda and Dr Alex Petrushevski are General Practitioners in Sydney, Australia who are in the business of chronic disease reversal. They offer holistic care that emphasises low carb, ketogenic and other lifestyle interventions in their clinic, Low Carb Specialists. In this episode discuss why so many GPs are disillusioned and burned out…
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Morley Robbins is an expert on the role of trace minerals in health. In this episode we go deeply into the biochemical mechanisms of copper and iron use in the body, particularly how they relate to mitochondrial health. We finish with a discussion about soil mineral depletion and the effect of agricultural herbicide glyphosate in chelating copper, …
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Clive Biggs is an expert breeder of Nguni, an indigenous African Sanga cattle breed. He operates Nandi Ngunis Stud in Eastern South Africa, which has the reputation as one of the highest quality Nguni breeding operations in the world. In this podcast we discuss the breed attributes including legendary fertility, robustness and farming efficiency. W…
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In this podcast we discuss the non-visual photoreceptor system, mealonpsin, why sunlight helps your lose weight, pro-opiomelanocortin (POMC), why building melanin is an important health strategy, and much more. Zaid K. Dahhaj is a men's health coach & co-host of The 2AM Podcast with extensive self education into the underlying drivers of chronic di…
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What can we expect from GPCRs in antibodies and biologics? In this episode of The Chain, host Rajesh Sundaresan, PhD, Scientific Leader and GSK Fellow of Protein Cell and Structural Sciences at GlaxoSmithKline, speaks with Thomas P. Sakmar, MD, Professor of Chemical Biology at Rockefeller University, about the history of GPCRs and various subunits,…
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Dr Lazslo Boros joins me for a deep dive into the role of deuterium in causing metabolic disease and the deposition of visceral fat. We go down to the level of the mitochondrion and learn exactly how foods enriched in deuterium, such as processed carbs and seed oils, contribute to metabolic dysfunction by wrecking the ATPase nanomotors in the inner…
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*APOLOGIES for the audio quality, Slim's connection was poor. However I have pushed this podcast out for the of the importance of the topics discussed. In this episode I talk again with Texas Slim, food sovereignty activist and founder of the decentralized beef supply movement the Beef Initiative. We discuss the industrial agricultural and processe…
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Thomas P. Seager, PhD is an engineer and Associate Professor in the School of Sustainable Engineering at Arizona State University. He is the expert in cold water therapy and the founder of the company Morozko Forge, which manufactures high quality ice baths. Thomas & I discuss the principles of cold therapy, how cold influences our physiology, usin…
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Owen Gwilliam is the owner and operator of Beef Back Better, a fully grass-fed beef supply company in El Salvador, Central America. With an extensive agricultural background in organic certification, he emigrated from Australia in 2022 seeking a new life and a new start. In this podcast we talk about the joys and challenges of starting a beef enter…
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Lily Nichols joins me to continue our exploration of optimal pregnancy and post-partum nutrition. This episode contains extremely valuable information on how to ensure your baby receives all the nutrients they need to thrive. We cover controversies surrounding seafood and raw fish consumption during pregnancy, the critical role of DHA, circadian rh…
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This is a recent interview I did with Kenford Bitana on the Lighthouse Podcast. In this episode, I am joined by Dr. Max Gulhane, a GP registrar and host of the Regenerative Health Podcast, who is also a strong proponent of circadian and nutritional strategies for optimizing health and reversing metabolic diseases. This episode provides valuable ins…
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In this episode of The Chain, Richard Bonneau, PhD, and Marcel Hop, PhD, of Genentech interview Tala Fakhouri, PhD, of the FDA on her thoughts on the discussion paper, “Using Artificial Intelligence & Machine Learning in the Development of Drug & Biologic Products” and the evolving role of AI/ML to create models and inform decisions in biopharmaceu…
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Tristan and I discuss the evidence for humans as electromagnetic organisms, the health consequences of removing ourselves the earth’s natural electromagnetic field, the science behind the harms of non-native EMF, how to mitigate non-native EMFs in your daily life, and much more. Tristan Scott is an Electrical Engineer and Health Optimization Consul…
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Dr Stephanie Seneff joins me for a deep dive into the pervasive herbicide glyphosate. We discuss four key ways glyphosate is wrecking human health, the fascinating synergies between glyphosate & deuterium, why Stephanie believes glyphosate is chiefly responsible for the autism epidemic, how we solve the glyphosate problem with regenerative ruminant…
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Andreas Chrisou is a personal trainer with a specialty in human movement and quantum/circadian health. He promotes ancestrally-appropriate exercises in outdoor settings that promote mobility and holistic health. We discuss optimizing training for our light environment, why you avoid exercising inside under artificial light, the benefits of groundin…
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With the whirlwind development of AI, it can be difficult to keep track of its uses in both research and the market. In this episode of The Chain podcast, host Ben Hackel, Professor of Chemical Engineering & Materials Science at the University of Minnesota, speaks with Enkelejda “Ledi” Miho, Professor of Digital Life Sciences at the University of A…
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In this conversation we discuss the nuances of seasonal eating, how women should do fasting and cold exposure, why leptin resistance is the first metabolic problem we should address, the effect of circadian disruption on cancer, and much more. Sarah is a leading quantum health practitioner with decade long experience in helping her clients optimise…
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Scott Zimmerman is an optics engineer and light researcher who has been studying the effect of non-visible light on the human body. He has made some fascinating and unexpected discoveries about the ways our bodies use infrared light from the sun and how melatonin, the so-called hormone of darkness, is actually being produced constantly in our mitoc…
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Ed Schroeder joins me to discuss the amazing Nguni cattle, their suitability as tools of regenerative farming & land regeneration, why they obviate the need for veterinary mRNA technology, how to conserve these animals as a endowment from nature to humanity. Ed Schroeder is a South African nature photographer and conservationist. His life mission i…
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Sara Pugh, PhD and I discuss why diabetes and obesity is a problem of circadian disruption and artificial light, the holes in centralized advice to avoid the sun, why we should eat foods low in deuterium, and MUCH much more. This is a must listen for any low-carb doctor or patient who is attempting to reverse metabolic disease or lose weight. Sara …
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What is the first step of getting into biotech? How do you make real progress in research? In honor of Ovarian Cancer Awareness Month, host Nimish Gera discusses these topics and more with Jonathan Sockolosky, PhD, Director of CSO Partner Team at Curie.Bio, in this special episode of The Chain. Jonathan details how he got started in biotech, what i…
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Dr Jalal Khan is one of Australia’s leading quantum health clinicians as well as a practicing dentist. In this fascinating conversation we cover Jalal’s thoughts on the centrality of circadian biology to health, why diet-only health paradigms lack the complete picture, role of mitochondrial dysfunction and disease, pro-opiomelanocortin (POMC), mela…
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Vivek is a world traveler, student of yoga spirituality and philosophy. I brought him on to discuss his fascinating framework of living called ‘the Five Ps”, which describes the different influences on our motivations, desires and actions in every day life. These are Paper, Pleasure, Power, Purpose and Peace. In this episode we talk about using the…
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In this episode of The Chain, Brandon Dekosky, Associate Professor at MIT, speaks with Adrian Bot, Founding Chief Scientific Officer and Executive Vice President of R&D at Capstan Therapeutics, about his experiences in leadership roles, his scientific journey, and how he started work on immunotherapy for cancer. Bot also shares what it's like to be…
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Anthony Jay, PhD is a world expert on the hidden danger of endocrine disrupting chemicals, also known as xeno-estrogens. These compounds are by-products of industrial farming, plastic manufacturing and common care products which signal like the female hormone estrogen, disrupting testosterone signaling and messing with reproductive functions in the…
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This is a recent interview I did with Meredith Oke on the Quantum Biology Collective podcast. It reflects my current thoughts on the role of light in health and how the circadian rhythm fits into optimal health. Dr Max Gulhane is a family physician based in New South Wales, Australia and is the host of the Regenerative Health Podcast. Early in his …
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Charlie Arnott joins me for an honest and self-reflective discussion on his journey from chemical farmer to biodynamic producer. We talk about Charlie’s conventional farming background, his current farming methods, the mindset of commodity agriculture, the question of feeding the world, the ethics of eating animals, and much more. Charlie Arnott is…
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In this special episode of The Chain, G. Jonah Rainey, Senior Director of Protein Engineering at Eli Lilly and Company, hosts a panel at PEGS 2023 to discuss strategies to engineer parameters for solid tumor-targeting T-cell-engagers. Guests Stephen J. Demarest from Tentarix Biotherapeutics, Michelle Morrow from F-Star Therapeutics, Inc., and Dario…
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Join us on August 6th in Albury, NSW for a holistic health summit combining CARNIVORE, REGENERATIVE FARMING and QUANTUM HEALTH. In this video @anthonychaffeemd , Dr. Max Gulhane, Dr. Jalal Khan and farmer Jacob Wolki give you a teaser into what they will be speaking about at REGENERATE Albury. From around the 10 minute mark we riff on the causes of…
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Dr Sean O’Mara joins me again to talk all things VISCERAL FAT. We cover the reasons why this key indicator of human disease is not being identified, diagnosed or treated, why you need an abdominal MRI, democratizing access to MRI, working out indoors vs outdoors and much more. Dr Sean O’Mara is a former Emergency Physician turned Lifestyle Physicia…
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