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Intestinal Permeability, a Focus for Disease Prevention
Manage episode 344220891 series 3393796
Content provided by Lauren Kern, MS, RD, LD, IFNCP, Lauren Kern, MS, RD, LD, and IFNCP. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Lauren Kern, MS, RD, LD, IFNCP, Lauren Kern, MS, RD, LD, and IFNCP or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
Understanding another layer of the DIGIN model to potential root causes of chronic disease- intestinal permeability.
This episode discusses:
- gut barrier function
- factors that influence intestinal permeability that may lead to chronic inflammation and disease - IBD, leaky gut, and more
- current assessment and testing techniques, including specific biomarkers
- how we can regulate the gut barrier with diet, prebiotics, and probiotics
- proposed dietary factors/interventions to support the gut barrier
References:
- Camilleri M. (2019). Leaky gut: mechanisms, measurement and clinical implications in humans. Gut, 68(8), 1516–1526. https://doi.org/10.1136/gutjnl-2019-318427
- Yu, S., Sun, Y., Shao, X., Zhou, Y., Yu, Y., Kuai, X., & Zhou, C. (2022). Leaky Gut in IBD: Intestinal Barrier-Gut Microbiota Interaction. Journal of microbiology and biotechnology, 32(7), 825–834. https://doi.org/10.4014/jmb.2203.03022
- Schoultz, I., & Keita, Å. V. (2020). The Intestinal Barrier and Current Techniques for the Assessment of Gut Permeability. Cells, 9(8), 1909. https://doi.org/10.3390/cells9081909
- Bischoff, S. C., Barbara, G., Buurman, W., Ockhuizen, T., Schulzke, J. D., Serino, M., Tilg, H., Watson, A., & Wells, J. M. (2014). Intestinal permeability--a new target for disease prevention and therapy. BMC gastroenterology, 14, 189. https://doi.org/10.1186/s12876-014-0189-7
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