#113 Gout: Uric acid targets, urate lowering therapy, and random questions from social media

The Curbsiders Internal Medicine Podcast

Master the management of gout with tips from expert, Tuhina Neogi MD, PhD, Professor of Medicine at Boston University School of Medicine. Topics include: how to initiate and titrate urate lowering therapy, guidelines controversy over uric acid targets, colchicine & NSAIDS for anti-inflammatory prophylaxis, uricosuric agents, febuxostat, HLA B5801, use of uric acid levels in the acute setting and more random gout facts.

Full show notes available at http://thecurbsiders.com/podcast. Join our mailing list and receive a PDF copy of our show notes every Monday. Rate us on iTunes, recommend a guest or topic and give feedback at [e-mail].

Credits:

• Written and produced by: Matthew Watto MD
• Hosts: Paul Williams MD, Stuart Brigham MD, Matthew Watto MD
• Guest: Tuhina Neogi MD, PhD

Time Stamps

• 00:00 Intro and guest bio
• 01:30 Allopurinol initiation and titration
• 07:10 Uricosuric therapy
• 09:10 Controversy over uric acid targets for gout
• 17:40 Parachutes and randomized controlled trials
• 19:15 Colchicine or NSAIDS for prophylaxis
• 23:20 Who needs febuxostat?
• 26:20 When to refer for gout, HLA B5801, and checking uric acid levels in the acute setting
• 33:29 Take home points
• 36:15 Outro

Tags: allopurinol, uric, urate, acid, level, therapy, management, gout, flare, crystal, arthritis, titration, probenecid, febuxostat, target, acr, acp, guidelines, nsaids, colchicine, hla b5801, septic, rheumatology, assistant, care, doctor, education, family, FOAM, FOAMim, FOAMed, health, hospitalist, hospital, internal, internist, meded, medical, medicine, nurse, practitioner, professional, primary, physician, resident, student