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The Second Act with Michael and John

Michael Newborn, John Ballenger

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Join hosts Michael (tech veteran and former product leader) and John (ret. USMC officer and Marine One pilot) on 'The Second Act' podcast, where ordinary people with extraordinary stories share their unique journeys in life's second act. From corporate executives to military veterans, consultants to entrepreneurs, the podcast delves into the diverse backgrounds and inspiring transformations of guests to highlight the power of grit, persistence, perspective, purpose and community.
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Naturopathy Today helps you find nature’s path to health and wellness. Hosts Dr. Michael Schwartz, ND and Steve Lankford are your guides on a journey to good health using wholistic naturopathic principles. Join them on a voyage to excellent health on all levels. New episodes every Monday. Hosts: Michael Schwartz, ND and Steve Lankford Contact: DrM@michaelshealth.com Design, Production, Editing and Voiceover: S. Phillips Music: Lauren Duski
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This podcast from NEJM Resident 360 takes a deep dive into key topics with expert clinicians and educators. As we explore the details of pathophysiology and critique the evidence behind clinical practice, these conversations are intended to give you better understanding of the topic and greater confidence when treating your patients.
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Exploring all things genetics. Dr Patrick Short, University of Cambridge alumnus and CEO of Sano Genetics, analyses the science, interviews the experts, and discusses the latest findings and breakthroughs in genetic research. To find out more about Sano Genetics and its mission to accelerate the future of precision medicine visit: www.sanogenetics.com
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Interviews with authors of Rational Clinical Examination systematic reviews in JAMA about the accuracy of the medical history, physical examination, and laboratory testing for the diagnosis of common medical conditions. JAMAevidence is an evidence-based medicine (EBM) resource created and maintained by JAMA Network to promote the use of EBM to improve patient care.
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The Household Health Podcast with Michael Heuninckx RN-BSN

A weekly podcast empowering listeners to take an active role in the Health of their entire Household!

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The Household Health Podcast is a weekly podcast that is dedicated to delivering quality healthcare information and education to promote a healthy Household. Managing the health of your Household is a 24/7, 7 day a week, 365 days a year job. No matter how large the Household is, living a healthy life is not easy. It truly is a journey and one that no one should walk alone in. In episodes of The Household Health Podcast, interview are conducted with different healthcare professionals that hav ...
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Being Agile is all about being more flexible, adaptable and being ready to change and adjust in this ever changing world. The often forgotten "secret" to living a truly fulfilling and happy life lies in your ability to be agile. Join Jon Voigt, founder of Agility Inc, as he shares the tips, strategies and insights from Entrepreneurs and Digital Leaders across the country on how to make your business and overall life more Agile. Each week Jon will be sharing the stories of today’s most Agile ...
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show series
 
0:00 Intro to The Genetics Podcast 1:00 Welcome to Ben Goldacre 02:22 Ben’s open data projects at the Bennett Institute and the challenges they aim to tackle 04:03 Using Electronic Health Records (EHR) to help the National Health Service improve care 06:18 The importance of software development within healthcare data and how to manage salary scales…
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0:00 Intro to The Genetics Podcast. 01:00 Welcome to Michelle. 02:00 Sstop codon diseases and how are they characterised 03:45 Diseases caused by premature stop codons in haploinsufficient genes. 04:35 The role of transfer RNA technology in finding solutions for premature stop codon diseases. 06:16 How Alltrna is engineering tRNAs which can bind to…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Ben Nelson (https://www.linkedin.com/in/bennelson303/) Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c42…
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0:00 Introduction 1:45 Almut’s research experience, including two recent publications on genome-scale metabolic reconstruction human microorganisms Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Nick Rotola (Founder & CEO of WE3 Group, Inc.) https://www.linkedin.com/in/nick-rotola-b87776149 Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/sho…
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0:00 Intro 1:30 Mavis’ career arc, from starting as a midwife to researching medical innovation and technology with an emphasis on advocacy and equity 7:00 Systemic issues that are easily overlooked in medical research and advancements Webinar: Participant Diversity: Increasing the Impact of Biomedical Research Webinar 10:00 Addressing Eurocentrici…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: John Macaskill https://www.linkedin.com/in/jonmacaskill/ Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c…
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0:00 Introduction 2:00 Allison’s personal journey to researching epilepsy and ring chromosome 20 syndrome 4:00 Biggest challenges families face with ring chromosome 20 syndrome 11:00 Incidence and prevalence of r(20) syndrome, and how we can improve data reliability 21:00 Applying next generation sequencing to r(20) syndrome gene research 29:00 Eng…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Alvin Cooper III (Founder of CStyled) Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a Apple: https:/…
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0:00 Introduction 1:30 Ingrid’s initial interests in genetics, paediatrics, and newborn screening 2:45 How the original BabySeq project, a pioneering newborn sequencing program got started, how it’s going, and the launch of BabySeq2 8:45 Lessons from BabySeq1 and goals for BabySeq2 10:30 Potential societal and long-term considerations for those inv…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Lindsey Nehls https://www.elevateleadership.com/ Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a App…
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0:00 Introduction 1:00 The backstory of how Kira first started DNA Today in 2012, when she was still in high school! 3:30 Some of Kira’s favourite topics she has discussed on DNA Today, including the legacy of Henrietta Lacks, and the story of a Glee actress with down syndrome 10:00 Kira’s best practices for podcasting, from over 10 years of experi…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Jacob Rupp (https://www.linkedin.com/in/jacobrupp/) BusinessLift (https://www.businesslift.com/) Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/sho…
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Dislocated hips in newborns can lead to complex surgery, interruption to family life, and premature osteoarthritis. Daniel Perry, MBChb(Hons), PhD, of Alder Hey Children's Hospital, University of Liverpool, discusses the clinical diagnosis of dislocated hips in newborns with JAMA Associate Editor David Simel, MD, MHS. Related Content: Does This Inf…
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0:00 Introduction 2:00 The value of an English Literature degree in designing and analysing research studies in medicine 3:45 Emma’s entrance to pharmacogenomics and her transition from practising physician to genetics research 6:00 How the East London Genes and Health program is increasing representation of diverse populations, namely South Asians…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Harley Blakeman (https://www.linkedin.com/in/harley-blakeman/) Honest Jobs (https://www.honestjobs.com/) Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify…
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0:00 Introduction 1:00 George’s upcoming big projects, including developing full recycling, renewing energy, creating bioweather maps, and harnessing citizen science 6:45 Progress in engineering viral resistance in humans, including thoughts from pre- and post- pandemic 11:00 A swapped genetic code that prevents viral infections and gene transfer b…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Marcus Long (linkedin.com/in/marcus-long-22278391) Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a A…
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0:00 Intro 0:40 Jake’s experiences as a serial entrepreneur starting five companies with a basis in genomic science 5:30 Opportunities for research and drug development in the realm of somatic science 9:20 Somatic evolution and how it provides valuable insights into disease mechanisms 12:30 Advantages and disadvantages of studying germline genome-w…
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In this episode of Curbside Consults, Dr. Andrew Dwyer, Director of Psychometrics at the American Board of Pediatrics (ABP), joins Mridula Nadamuni, former editorial fellow, to discuss the process of creating and administering pediatric board examinations. Andy Dwyer holds a PhD in educational psychology and an MS in statistics from the University …
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Todd Lancaster (https://www.linkedin.com/in/1toddlancaster) Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb6…
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Show Notes: 0:00 Introduction 1:20 How polydactyl mutations can inform research on non-coding variant mechanisms The importance of low-affinity binding between transcription factors and targets How these lessons can help us improve our understanding of drug and target discovery See Veera’s January round-up for more information: https://www.gwasstor…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a Apple: https://podcasts.apple.com/us/podcast/the-second-act…
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0:00 Introduction 0:45 Jean’s personal experiences with family members with genetic ALS 10:00 Jean’s thoughts on the barriers and facilitators to providing treatment for those with genetic ALS 13:20 Insights into C9orf72, a common genetic determinant of ALS, and how it can also be associated with FTD 16:10 Jean’s experiences as an active advocate f…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Martin Skea linkedin.com/in/martin-skea/ https://eit.europa.eu/news-events/news/eit-community-new-european-bauhaus-catalyse-programme-looking-socially-innovative Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me"…
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0:00 Introduction 1:05 Insights into the PD GENEration’s (a programme from the Parkinson's Foundation) milestones and progress points for the upcoming year 3:30 The shifting attitudes and perspectives of neurologists and healthcare workers at the PD GENEration 5:50 Insights into Nacho’s work with the genetics of Parkinson’s disease 10:20 Barriers a…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Michelle "Mace" Curran michaelandjohn.com/mace instagram.com/mace_curran linkedin.com/in/macecurran/ Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com…
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0:00 Intro 0:25 Mazen’s lifelong commitment to furthering the field of precision medicine in liver disease research, fueled by a personal connection of his grandmother developing MASH cirrhosis 2:30 Breakthroughs in the field of metabolic dysfunction-associated steatotic liver disease (MASLD) since the beginning of Mazen’s career 5:30 The potential…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Erik Thompson (https://thompsonleadership.com/) Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a Appl…
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0:00 Introduction 0:25 Julia’s personal experience with ultra-rare diseases within her family 10:25 The importance of increasing accessibility to genetic testing across populations to learn more about ultra-rare diseases 14:00 The origin story of Rare Trait Hope Fund 23:50 Current research and next steps in developing potential gene therapies for a…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Isaac Lee (linkedin.com/in/isaaclee1) Network/Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a Apple: https:/…
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0:00 Introduction 1:25 How Lord O’Shaughnessy became involved in scientific policy making and his path to writing the UK Commercial Clinical Trials Review. 04:05 How Lord O’Shaughnessy pivoted from education to a focus on life sciences 06:38 The biggest challenges Lord O’Shaughnessy faced during his time as Parliamentary Under Secretary for Health …
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Eric Baliruno (Linkedin) Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a Apple: https://podcasts.apple.com/u…
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0:00 Introduction 01:10 How growing up in Malawi planted the seeds for John’s career in medicine and transition to therapeutic development 04:35 Why John focuses on rare diseases and conditions such as asthma 06:01 What has changed over the last decade in terms of treating and understanding asthma and the progress that genetics has enabled 07:31 Wh…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: John Buckley LinkedIn: https://www.linkedin.com/in/john-buckley-6b96288/ Military.com: 8 Hard-Earned Tips on Military Transition Better Together story LinkedIn articles Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" …
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0:00 Introduction 0:50 Holly’s background and career so far 03:30 Complex decision-making and multiple risk factors: Family history, genetics, phenotypes and beyond 07:05 Changes within the last decade to help people make complex, sometimes subjective, healthcare decisions 09:20 Impact on people: The RTI’s mission and the Early Check Study 13:45 Ne…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Mirela Mus linkedin.com/in/mirelamus Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a Apple: https://podcasts…
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Summary: 0:00 Introduction 01:01 How Leslie got into the field of synthetic biology and engineering, and her career journey so far 02:45 What Leslie accomplished during her postdoc and recent transformations in the field of genomics 05:57 The impacts of non-coding regions of the genome and the outcome of deletions 08:20 How long it takes to make ch…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Vineet Rajan https://www.linkedin.com/in/vineetrajan23 Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a Apple…
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Summary: 0:00 Introduction 0:50 Reflections from the 34th International Symposium on ALS/MND in Basel 1:50 Michael’s professional journey, initial challenges he encountered, and how the field of neurology has evolved over the years 3:10 An introduction to the ALS landscape, including its presentation, the genes involved, and potential treatment opt…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Dave Lucas https://www.linkedin.com/in/dave-lucas-a6962b179/ Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a…
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0:00 Introduction to Dr. Nicole Paulk, a pioneer in AAV research and the founder of Siren Biotechnology 0:50 The moments that shaped Nicole’s career path and her passion for gene therapy and AAV research 9:20 Nicole’s academic research career and her transition from academia to the biotech industry 23:00 The story behind the founding of Siren Biote…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Shanna Weber linkedin.com/in/shanna-weber Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a Apple: https://pod…
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0:00 Introduction 01:00 Chris’ background and career to date 02:10 What is the Enigma Project? 04:48 How is genetics being applied to drug discovery today and how does proteomics fit in? 09:23 When the UKBiobank Pharma Proteomics Project began and how long it took to set up 10:57 54k UK Biobank participants tested - discussion of findings 14:33 The…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Scott Bright (brightcheck.com) Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a Apple: https://podcasts.apple…
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Summary: 0:00 Introduction 5:45 Lessons learned from 15 years at GSK: How has genetics and drug discovery evolved over time? 8:10 Matt’s seminal 2015 paper: Quantifying the impact of human genetic evidence on the probability of success in drug development 11:40 Which types of genetic evidence are the best drivers of success in clinical trials? 13:3…
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Starring: Michael Newborn (@michaelnewborn) John Ballenger (@john-ballenger53) Guest: Ann Moul (secondactstories.com) Produced by: Seltzer Kings (@seltzerkings) (seltzerkings.com) Theme Music: "You Can't Stop Me" by Andy Mineo Listen Here: Spotify: https://open.spotify.com/show/71Uji4fPLsnGEJjeAqomiJ?si=77e3d7bb636c422a Apple: https://podcasts.appl…
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Summary: 0:00 Introduction 1:45 Wendy’s early career looking into the genetics of diabetes through mouse models 6:23 A high altitude view: Cutting through hype to spot the next wave of game-changing technology 8:03 The role of policy and communication: how Wendy’s work goes beyond the lab to create real-world impact 11:20 Wendy’s choice to do an MD…
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