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42. Antidepressant induced homicide (Rebroadcast)

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Manage episode 389345700 series 2934387
Content provided by Roger K. McFillin, Psy.D., ABPP, Roger K. McFillin, and ABPP. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Roger K. McFillin, Psy.D., ABPP, Roger K. McFillin, and ABPP or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

In 2011, a paper was published in Pharmacogenomics and Personalized Medicine examining the relationship of antidepressants and akathisia side effects in those with genetic mutations in the metabolizing genes of the CYP450 family. In the study, eight of the subjects had committed homicide and many more became extremely violent while on antidepressants.

On today’s podcast we welcome one of the co-authors, Christopher Crotty, and subject, David Carmichael, to share their stories.

Note: This podcast episode is designed solely for informational and educational purposes, without endorsing or promoting any specific medical treatments. We strongly advise consulting with a qualified healthcare professional before making any medical decisions or taking any actions.

*If you are in crisis or believe you have an emergency, please contact your doctor or dial 911. If you are contemplating suicide, call 1-800-273-TALK to speak with a trained and skilled counselor.

RADICALLY GENUINE PODCAST

Dr. Roger McFillin / Radically Genuine Website

YouTube @RadicallyGenuine

Dr. Roger McFillin (@DrMcFillin) / X (Twitter)

Substack | Radically Genuine | Dr. Roger McFillin

Instagram @radicallygenuine

Contact Radically Genuine

—-----------

FREE DOWNLOAD! DISTRESS TOLERANCE SKILLS

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ADDITIONAL RESOURCES

  1. Lucire, & Crotty, C. (2011). Antidepressant-induced akathisia-related homicides associated with diminishing mutations in metabolizing genes of the CYP450 family. Pharmacogenomics and Personalized Medicine, 65. https://doi.org/10.2147/pgpm.s17445

16:00 Zhou, Y., Ingelman-Sundberg, M., & Lauschke, V. (2017). Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects. Clinical Pharmacology & Therapeutics, 102(4), 688–700. https://doi.org/10.1002/cpt.690

30:00 - Know Your Drugs

39:30 - David Carmichael v. GlaxoSmithKline Inc.

40:00 - Carmichael, D. Calm, organized, homicidal behaviour – my connection to school shooters. Mad In America.

46:15 - RxISK Prescription Drug Side Effects

  continue reading

148 episodes

Artwork
iconShare
 
Manage episode 389345700 series 2934387
Content provided by Roger K. McFillin, Psy.D., ABPP, Roger K. McFillin, and ABPP. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Roger K. McFillin, Psy.D., ABPP, Roger K. McFillin, and ABPP or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

In 2011, a paper was published in Pharmacogenomics and Personalized Medicine examining the relationship of antidepressants and akathisia side effects in those with genetic mutations in the metabolizing genes of the CYP450 family. In the study, eight of the subjects had committed homicide and many more became extremely violent while on antidepressants.

On today’s podcast we welcome one of the co-authors, Christopher Crotty, and subject, David Carmichael, to share their stories.

Note: This podcast episode is designed solely for informational and educational purposes, without endorsing or promoting any specific medical treatments. We strongly advise consulting with a qualified healthcare professional before making any medical decisions or taking any actions.

*If you are in crisis or believe you have an emergency, please contact your doctor or dial 911. If you are contemplating suicide, call 1-800-273-TALK to speak with a trained and skilled counselor.

RADICALLY GENUINE PODCAST

Dr. Roger McFillin / Radically Genuine Website

YouTube @RadicallyGenuine

Dr. Roger McFillin (@DrMcFillin) / X (Twitter)

Substack | Radically Genuine | Dr. Roger McFillin

Instagram @radicallygenuine

Contact Radically Genuine

—-----------

FREE DOWNLOAD! DISTRESS TOLERANCE SKILLS

—----------

ADDITIONAL RESOURCES

  1. Lucire, & Crotty, C. (2011). Antidepressant-induced akathisia-related homicides associated with diminishing mutations in metabolizing genes of the CYP450 family. Pharmacogenomics and Personalized Medicine, 65. https://doi.org/10.2147/pgpm.s17445

16:00 Zhou, Y., Ingelman-Sundberg, M., & Lauschke, V. (2017). Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects. Clinical Pharmacology & Therapeutics, 102(4), 688–700. https://doi.org/10.1002/cpt.690

30:00 - Know Your Drugs

39:30 - David Carmichael v. GlaxoSmithKline Inc.

40:00 - Carmichael, D. Calm, organized, homicidal behaviour – my connection to school shooters. Mad In America.

46:15 - RxISK Prescription Drug Side Effects

  continue reading

148 episodes

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