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#137 - Paul Offit, M.D.: An expert perspective on COVID-19 vaccines
Manage episode 277635389 series 2432666
- How Paul’s experience as a child in a chronic care hospital as child informed his path in pediatrics and vaccine development (3:30);
- Addressing the anti-vaccination sentiment and explaining the fraudulent origins of the anti-vaccination movement (8:00);
- Lessons and insights from 26 years studying rotavirus and creating a successful rotavirus vaccine (17:00);
- Developing a new vaccine: the different phases of clinical trials, overall timeline, and financial costs (27:15);
- Operation Warp Speed: the expedited process of creating a coronavirus vaccine (32:30);
- Various vaccine strategies—RNA, DNA, virus vector—and the challenges associated (35:00);
- The Moderna and Pfizer mRNA vaccines: strategy, timeline, and Emergency Use Authorization (41:15);
- Paul’s confidence level in the safety of the first coronavirus vaccines (48:30);
- The risks associated with different types of vaccines, and updates on the Johnson & Johnson and Astrazeneca coronavirus vaccines (52:15);
- What we know about the coronavirus vaccines approved in Russia and China (55:45);
- The latest on the Merck coronavirus vaccine (57:15);
- The recombinant/purified protein vaccine approach for coronavirus—big players, risks, and the best vaccine for the elderly (57:45);
- Attenuated and inactivated vaccine strategies for coronavirus (1:02:00);
- The genetic drift of SARS-CoV-2: Impacts for protection and vaccine development (1:02:30);
- Paul’s take on the hypothesis that a previous coronavirus infection offers protection against the novel COVID-19 (1:06:45);
- Addressing the concern that antibodies fade over time (1:09:15);
- Blood type and protective against coronavirus (1:13:00);
- Distribution: the challenge of prioritizing the limited doses of vaccines after approval (1:13:15);
- Paul’s perspective on COVID-19 vaccine safety (1:16:15);
- Considerations regarding vaccinating children for coronavirus and the role of a fever immune response (1:21:45);
- Why vaccine development can be challenging and risks of current COVID-19 strategies (1:29:45); and
- More.
Learn more: https://peterattiamd.com/ Show notes page for this episode: https://peterattiamd.com/pauloffit Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on Facebook | Twitter | Instagram.
346 episodes
Manage episode 277635389 series 2432666
- How Paul’s experience as a child in a chronic care hospital as child informed his path in pediatrics and vaccine development (3:30);
- Addressing the anti-vaccination sentiment and explaining the fraudulent origins of the anti-vaccination movement (8:00);
- Lessons and insights from 26 years studying rotavirus and creating a successful rotavirus vaccine (17:00);
- Developing a new vaccine: the different phases of clinical trials, overall timeline, and financial costs (27:15);
- Operation Warp Speed: the expedited process of creating a coronavirus vaccine (32:30);
- Various vaccine strategies—RNA, DNA, virus vector—and the challenges associated (35:00);
- The Moderna and Pfizer mRNA vaccines: strategy, timeline, and Emergency Use Authorization (41:15);
- Paul’s confidence level in the safety of the first coronavirus vaccines (48:30);
- The risks associated with different types of vaccines, and updates on the Johnson & Johnson and Astrazeneca coronavirus vaccines (52:15);
- What we know about the coronavirus vaccines approved in Russia and China (55:45);
- The latest on the Merck coronavirus vaccine (57:15);
- The recombinant/purified protein vaccine approach for coronavirus—big players, risks, and the best vaccine for the elderly (57:45);
- Attenuated and inactivated vaccine strategies for coronavirus (1:02:00);
- The genetic drift of SARS-CoV-2: Impacts for protection and vaccine development (1:02:30);
- Paul’s take on the hypothesis that a previous coronavirus infection offers protection against the novel COVID-19 (1:06:45);
- Addressing the concern that antibodies fade over time (1:09:15);
- Blood type and protective against coronavirus (1:13:00);
- Distribution: the challenge of prioritizing the limited doses of vaccines after approval (1:13:15);
- Paul’s perspective on COVID-19 vaccine safety (1:16:15);
- Considerations regarding vaccinating children for coronavirus and the role of a fever immune response (1:21:45);
- Why vaccine development can be challenging and risks of current COVID-19 strategies (1:29:45); and
- More.
Learn more: https://peterattiamd.com/ Show notes page for this episode: https://peterattiamd.com/pauloffit Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on Facebook | Twitter | Instagram.
346 episodes
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