A Newly Discovered Dietary Hazard: TMAO

Diet Science

Trimethylamine-N-oxide (TMAO) is a harmful compound produced by gut bacteria. Elevated TMAO levels can significantly influence the development of heart disease, type 2 diabetes, chronic kidney disease, cancer, and fatty liver disease. Listen in this week as Dee explains which foods increase the production of TMAO in the gut, and how you can optimize the health of your gut.

References:

Li, X. S., Obeid, S., Klingenberg, R., Gencer, B., Mach, F., Räber, L., Windecker, S., Rodondi, N., Nanchen, D., Muller, O., Miranda, M. X., Matter, C. M., Wu, Y., Li, L., Wang, Z., Alamri, H. S., Gogonea, V., Chung, Y. M., Tang, W. H., Hazen, S. L., … Lüscher, T. F. (2017). Gut microbiota-dependent trimethylamine N-oxide in acute coronary syndromes: a prognostic marker for incident cardiovascular events beyond traditional risk factors. European Heart Journal, 38(11), 814–824. https://doi.org/10.1093/eurheartj/ehw582

Shan, Z., Sun, T., Huang, H., Chen, S., Chen, L., Luo, C., Yang, W., Yang, X., Yao, P., Cheng, J., Hu, F. B., & Liu, L. (2017). Association between microbiota-dependent metabolite trimethylamine-N-oxide and type 2 diabetes. The American Journal of Clinical Nutrition, 106(3), 888–894. https://doi.org/10.3945/ajcn.117.157107