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Welcome to a new era of conversation—where artificial intelligence explores what it means to live longer and better. Created and guided by Dr. Trinh, The Longevity Podcast uses AI hosts to bring scientific discovery, health innovation, and human wisdom together. Through AI-driven discussions inspired by real research and medical insight, each episode reveals practical tools for optimizing your healthspan and mindspan—rooted in science, shaped by compassion. Mind. Body. Spirit. Powered by Sci ...
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Living with Sunny

Sunny Gurpreet Singh

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I seek wellbeing, authentically, passionately, relentlessly. In my journey, I meet new people every day. From all walks of life. The Living with Sunny podcast is where I converse with the people I meet — some of the best minds on the planet from domains such as mental health, mindfulness, business, psychology, policy research, and more. Our conversations range from casual and soulful to uplifting and enlightening, touching upon the experiences that defined them; their work and passion; how t ...
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“Trở Về Chính Mình” là podcast của Đào Chi Anh, chia sẻ những câu chuyện và bài học từ hành trình làm lãnh đạo, người mẹ ba con, và một phụ nữ Việt Nam hiện đại. Cùng nhau, chúng ta sẽ khám phá cách kết nối sâu sắc với chính mình, cân bằng sự nghiệp và cuộc sống, vượt qua thử thách, và sống có mục đích. Từ kinh nghiệm làm startup, lãnh đạo trong tập đoàn lớn, và tác giả cuốn sách “Trở Về Nhà”, mỗi tập sẽ truyền cảm hứng để bạn sống chân thật và hạnh phúc hơn mỗi ngày. Hãy cùng trở về chính m ...
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Send us a text This episode breaks down the science of lasting happiness and explains why feelings are evidence—not the goal. Instead of chasing emotional highs, we map a practical, four-pillar plan across faith, family, friendship, and work to help you earn satisfaction, deepen meaning, and anchor your days in genuine connection. The goal is not m…
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Send us a text This episode reframes leadership as a biological state—not a checklist—and shows how inner stability enables courage, influence, and consistently better decisions. Instead of treating leadership as personality or tactics, we explore how the nervous system shapes mindset, emotional control, and the ability to act boldly under uncertai…
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Send us a text This episode argues that chronic disease is one story told in many dialects—and that story is stalled energy flow. We reframe health as organized, efficient energy movement through the body, and show how mitochondria act not just as fuel generators, but as highly tuned sensing and decision hubs that determine whether the system thriv…
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Send us a text This episode traces how metabolic dysfunction drives mood disorders—from brain energy failure and inflammation to insulin resistance that reshapes neural circuits—and lays out the emerging biomarkers and treatments that enable true precision mental health care. Rather than viewing depression and anxiety as purely psychological, we ex…
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Send us a text This episode trades spreadsheets for soul and maps a clear, practical path out of corporate misery through three life-changing promises: remove the nail, follow your energy, and go all in. Through story, psychology, and embodied wisdom, we reveal why two inner voices battle for control—fear mind versus intuitive intelligence—and how …
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Send us a text This episode explores why 70–90% of retreat participants show rapid, uniform shifts in inflammation, immunity, and gene expression within just seven days—and how Dr. Hemel Patel is designing blinded, large-scale studies to rigorously test those extraordinary claims. We connect epigenetic pressure, beneficial stress, mitochondrial hea…
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Send us a text This episode explores how the brain’s glymphatic system clears metabolic waste, why that drainage slows with age and APOE4 risk, and how patterned TMS may offer a breakthrough path to restoring flow and memory. Emerging evidence shows that glymphatic function is not fixed—it’s plastic—and can be selectively improved in older adults w…
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Send us a text This episode explores how the brain’s glymphatic system flushes metabolic waste during sleep—and why deep non-REM slow waves act as the pump that powers this nightly cleanup. We trace the anatomy, physiology, and aging-related vulnerabilities of this essential yet still underappreciated system, linking it to long-term cognitive healt…
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Send us a text This episode explores how a new ear-mounted impedance device finally allows real-time tracking of the brain’s glymphatic cleaning system—and what it reveals about the 20% boost in waste clearance during deep sleep. We break down the biology behind amyloid and tau removal, explain the technology, and map how continuous data may accele…
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Send us a text This episode reveals how the glymphatic system clears toxic proteins during deep sleep, why arterial pulsation acts as the engine of this process, and how your daily habits can either support or block this essential nightly rinse. We translate complex physiology into practical steps you can take tonight to protect long-term brain hea…
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Send us a text This episode explores how chronic insomnia disrupts cognition—and why repairing the brain’s glymphatic cleaning cycle may be the key to restoring mental clarity. We break down new research showing that low-frequency rTMS not only produces rapid sleep improvements but also triggers slower, durable cognitive gains tied directly to enha…
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Send us a text This episode presents a clear, data-backed breathing protocol designed to raise low HRV and strengthen stress resilience—using a method so simple it can be anchored to everyday transitions. We break down why HRV is a powerful reflection of nervous system adaptability and how slow, structured breathing can shift your physiology toward…
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Send us a text This episode maps the biology of fear and trauma and explains why the brain can lock in threat after just a single experience—then shows how real healing requires replacing, not erasing, old associations. We break down the physiology of stress, the circuitry of fear learning, and the cognitive stories that shape how we interpret dang…
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Send us a text This episode argues for a unified, metabolic model of mental health—placing mitochondria at the center of mood, cognition, hormones, and stress. Instead of treating mental illness as purely psychological, we trace how cellular energy production shapes everything from neurotransmitter synthesis to hormonal balance and epigenetic signa…
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Send us a text This episode breaks down why motivation feels scarce—and how modern habits train the brain to crave ease over effort—then offers a practical dopamine reset that rebuilds pursuit, focus, and follow-through. Instead of treating low motivation as a character flaw, we explore the neurobiology of dopamine as a pursuit signal, not a pleasu…
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Send us a text How little exercise does it really take to extend your life? This episode breaks down the science behind the minimum effective dose and reveals why small, strategic bursts of movement can create massive benefits for longevity, heart health, and brain resilience. The research shows a striking nonlinear dose–response curve, meaning the…
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Send us a text Exercise is one of the most powerful tools for brain health—and in this episode, we break down the five scientifically validated pathways that explain exactly how it protects cognition. From BDNF-driven neurogenesis to improved cerebral blood flow and lower inflammation, we explore the precise mechanisms that strengthen memory, suppo…
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Send us a text This episode reframes Alzheimer’s disease by tracing how the plaque-first narrative emerged from rare genetic mutations—and why most age-related cognitive decline is actually driven by systemic metabolic and microvascular health. We break down the evidence across neurodegenerative diseases, highlight what truly predicts risk, and out…
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Send us a text This episode argues that K-12 struggles for a simple reason: students advance by time instead of mastery, creating widening skill gaps that erode confidence and long-term performance. We explore how AI, mastery learning, and a smarter motivation model can help most students reach top-tier achievement—while freeing up time instead of …
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Send us a text This episode challenges the intensity-first mindset in fitness and reveals why complex movement—rather than harder movement—delivers the biggest cognitive rewards. Drawing on a major umbrella review, we explore how mind–body practices outperform traditional aerobic and resistance exercise for executive function, stress regulation, an…
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Send us a text We show how the minimum effective dose of exercise delivers outsized gains for heart and brain health with minutes, not hours. The science points to a steep benefit curve from zero to brief, intense movement, with clear targets you can hit today. • redefining exercise as a threshold, not a time block • nonlinear dose–response curve a…
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Send us a text This episode reframes longevity by highlighting two underappreciated pillars—kidney function and precise blood pressure control—as major determinants of how many healthy years you actually get. We walk through the labs you should request, the lifestyle stack that consistently protects renal health, and the new evidence that overturns…
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Send us a text This episode breaks down what actually happens when you drink alcohol—and why even small daily amounts meaningfully increase cancer risk. We trace the biochemical chain from ethanol to acetaldehyde, a highly reactive toxin that disrupts DNA methylation, accelerates tumor growth, and weakens immune surveillance. The goal is clarity: w…
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Send us a text This episode breaks down the strongest scientific evidence that exercise protects your brain immediately and over the long arc of your life. We translate major studies into clear, actionable steps, showing how aerobic workouts sharpen attention today, how HIIT strengthens executive function, and how decades of sustained fitness can d…
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Send us a text This episode turns sauna use from a spa luxury into a science-backed protocol for heart health, brain protection, and mood resilience. We explain how heat exposure mimics the cardiovascular effects of aerobic exercise, activates cellular repair pathways, and delivers benefits that compound when paired with your existing training. The…
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Send us a text A structured longevity system combining sleep, nutrition, protein dosing, training, and mental health—designed for outsized, measurable gains. In this episode, we unpack a highly structured, fully integrated approach to longevity that treats sleep, nutrition, exercise, and mental health as one system. The goal isn’t imitation—it’s tr…
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Send us a text A no-regret longevity blueprint: VO2 max, lipid control, insulin health, APOB, sleep, and the habits that stack the odds for a longer life. This episode breaks down the biggest levers that reliably extend lifespan—and why most longevity noise distracts from what truly moves the needle. We begin by reframing family history as a more a…
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Send us a text Creatine isn’t just for muscle—it’s a rapid ATP buffer for stressed brains, with dosing strategies that finally unlock real cognitive benefits. In this episode, we flip the creatine story from gym supplement to cognitive stabilizer. We explain the phosphocreatine system and how creatine serves as a rapid ATP buffer for neurons under …
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Send us a text Discover how to beat directed attention fatigue with nature resets, deep-work design, and Kaplan’s proven restoration principles for sharper focus and cognition. In this episode, we break down the science of directed attention fatigue, why it shows up earlier than most people realize, and how “powering through” only drains cognitive …
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Send us a text Methylene blue’s mitochondrial effects, oxidative stress repair, dosing risks, MAO inhibition, serotonin syndrome, sourcing, and the economics blocking large trials. In this episode, we trace the surprising evolution of methylene blue from a lab dye to a potential mitochondrial enhancer. We explain how it participates in electron shu…
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Send us a text Explore the biology of stress, motivation, and status—through dopamine, testosterone, estrogen, and the amygdala’s rapid threat circuits. In this episode, we map the full landscape of how stress and motivation arise in the brain and body. We start with the concept of stress as duration plus valence, showing how the amygdala makes spl…
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Send us a text Trigger adult neuroplasticity with error signals, urgency, dopamine, state control, and balance-based movement to accelerate learning. In this episode, we present a clear, actionable framework for activating adult neuroplasticity, allowing you to learn faster without burnout or endless repetition. We begin by reframing errors as the …
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Send us a text A three-layer happiness model—sensory contrast, story comparison, and meaning—turned into a practical plan using your signature strengths. In this episode, we unpack a three-level framework of happiness that makes the concept concrete and actionable. We begin with sensory-level happiness, showing how hedonic adaptation works and why …
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Send us a text A clear look at anti-aging supplements—NAD, NR, NMN, rapamycin, berberine—versus the proven longevity levers: sleep, training, nutrition, and light. In this episode, we dissect the anti-aging supplement boom and separate hype from what actually holds up in humans. We revisit resveratrol’s limitations in real-world data and how its ro…
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Send us a text This episode explains why most energy crashes have nothing to do with willpower and everything to do with mistimed biological signals. We map how the brain, hormones, and mitochondria coordinate energy—and why disruptions in these systems create fatigue that feels mysterious but is completely understandable. You’ll learn how mitochon…
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Send us a text We pull apart the engine behind David Goggins’ discipline, mapping his friction-first lifestyle to the brain’s willpower circuits and the study methods that let him learn what doesn’t come easy. Fear of comfort, not love of pain, drives a daily practice that keeps his resolve alive. • brutal origins, obesity, and a hated job • pen-an…
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Send us a text We explore how the brain fuses sight and sound into one stable reality, predicts away saccade blur, and even moves the eardrum to align hearing with vision. We connect top-down control to simulation-based thinking, environmental acoustics, deep focus, and the social power of rhythm. • superior colliculus as early multisensory hub • p…
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Send us a text We map the biology of fear from the autonomic seesaw to the HPA axis, then show how the amygdala links threat to motivation and how the prefrontal cortex writes the story that guides action. We share a two-step framework to extinguish old circuits and build stronger, positive ones with therapy, breathing, and smart supplement timing.…
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Send us a text We expose why PCOS and endometriosis remain widely undiagnosed, how to spot the real signs, and what to demand from doctors to protect fertility and long-term health. Practical tools, from Rotterdam criteria to targeted treatments and fertility planning, turn confusion into action. • PCOS prevalence, underdiagnosis, and misunderstood…
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Send us a text We map the nine training adaptations, the law of progressive overload, and the exact levers that drive strength, size, and endurance. Clear protocols, simple hydration math, and smart use of breathing, heat, and cold turn guesswork into growth. • defining nine adaptations and why fat loss is a byproduct • progressive overload as the …
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Send us a text We unpack how dopamine actually governs motivation through a balance of tonic baseline and phasic peaks, why big highs lead to slumps, and how to build steady drive without crashes. We share tools like cold exposure, intermittent rewards, effort-first framing, and social connection, plus cautions on supplements and stimulants. • defi…
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Send us a text We map the brain’s universal blueprint for human connection and show why loneliness is a biological drive, not a flaw. Then we offer two levers—synchronization and cognitive empathy—to build stronger bonds that protect health and resilience. • one neural template for attachment across relationships • isolation as a stressor raising c…
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Send us a text We explain the true differences between fear, stress, anxiety, and trauma, then map the circuits that make threat memories stick and how to unwind them. The path forward is clear: extinguish the old response and build a stronger, purpose-driven one using therapy, chemistry, and practice. • operational definitions of fear, stress, anx…
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Send us a text We map a working model of a healthy mind where agency and gratitude are earned outcomes of solid inner engineering. We trace structure, function, and drives, then give a practical audit to escape overthinking, envy, and demoralization. • flipping from pathology to the engineering of a healthy self • agency and gratitude as outcomes s…
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Send us a text We trace a clear path from childhood clues to a focused life’s task, then map the social terrain where power, masks, and influence shape daily choices. Along the way we separate false highs from real flow, explore love built on values, and turn anxiety and urgency into fuel for mastery. • finding the internal radar from early impulse…
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Send us a text We unpack why many physicians feel financially stuck despite high pay: the lost decade of compounding, crushing student debt, lifestyle inflation, and time poverty that leads to reactive decisions. We show how RVU income, 1099 structures, liability risk, and the advice gap require a tailored plan that starts with protection and disci…
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Send us a text Forgiveness asks us to face real wounds without excusing them and to release bitterness into God’s hands. We draw on Scripture, Joseph’s story, and Mandela’s example, then offer simple steps and a closing prayer to help you start. • what forgiveness is and is not • why grace is greater than pain • forgiveness as a mark of spiritual m…
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Send us a text We reflect on why love stands above faith and hope, exploring how patient, humble, and sacrificial love heals relationships and realigns motives with God’s heart. We look at Jesus washing feet, Saint Francis’ embodied compassion, and three simple practices that make love concrete today. • love as the highest spiritual gift • choosing…
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Send us a text We reflect on what it means to walk by faith rather than sight, drawing insight from Peter on the water and the documented prayer life of George Mueller. We end with three practical steps and a short prayer to help you trust God when fear rises. • faith as confidence in God’s character • Peter’s focus on Jesus versus the storm • Geor…
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Send us a text We reflect on how surrender shifts the weight of life from our control to God’s care, bringing clarity, peace, and space for breakthrough. Scripture, history, and simple practices show how small daily yeses shape a trusting heart. • the meaning of surrender as trusting God over preference • peace as the fruit of releasing control • M…
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