How to interpret the pattern of high citrate, low cis-aconitate, low glutamate, and high glutamine. | Masterjohn Q&A Files #45

Mastering Nutrition

Content provided by Chris Masterjohn, PhD and Chris Masterjohn. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Chris Masterjohn, PhD and Chris Masterjohn or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

4+ y ago 1:25

MP3•Episode home

Archived series ("Inactive feed" status)

When? This feed was archived on February 29, 2024 23:14 (2M ago). Last successful fetch was on January 13, 2024 12:53 (3M ago)

Why? Inactive feed status. Our servers were unable to retrieve a valid podcast feed for a sustained period.

What now? You might be able to find a more up-to-date version using the search function. This series will no longer be checked for updates. If you believe this to be in error, please check if the publisher's feed link below is valid and contact support to request the feed be restored or if you have any other concerns about this.

Question: How to interpret the pattern of high citrate, low cis-aconitate, low glutamate, and high glutamine.

The aconitate and citric acid are markers on the citric acid cycle where we metabolize most of our energy. If citric acid is high and isocitric acid is low, (this must be the Great Plains Test which doesn't have isocitrate/cis-aconitate) that would indicate oxidative stress.

In terms of the glutamate being low --- if your glutamate is low and your glutamine is on the high side, then you probably have ammonia generation from somewhere that you're mopping up with glutamate. That would be my guess, but that's another can of worms to open.

This Q&A can also be found as part of a much longer episode, here: https://chrismasterjohnphd.com/podcast/2019/02/24/ask-anything-nutrition-feb-17-2019/

If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up with a 10% lifetime discount here: https://chrismasterjohnphd.com/q&a

Access the show notes, transcript, and comments here.

701 episodes